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  1. Book ; Thesis: Charakterisierung der humoralen Immunantwort gegen p16INK4a,p53, HPV16 E6 und HPV16 E7 bei Zervixkarzinompatientinnen

    Reuschenbach, Miriam

    2008  

    Author's details vorgelegt von Miriam Reuschenbach
    Subject code 616.994
    Language German
    Size X, 123 S. : Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2009
    HBZ-ID HT016734708
    Database Catalogue ZB MED Medicine, Health

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    2011 E 1278 order for loan Magazin

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  2. Article ; Online: Community Health Nursing in der Gemeinde: Mittendrin statt nur dabei.

    Primig, Miriam / Reuschenbach, Bernd

    Urologie (Heidelberg, Germany)

    2023  Volume 62, Issue 8, Page(s) 825–829

    Title translation Community Health Nursing: A central part in the community.
    MeSH term(s) Humans ; Community Health Nursing
    Language German
    Publishing date 2023-06-06
    Publishing country Germany
    Document type Journal Article
    ISSN 2731-7072
    ISSN (online) 2731-7072
    DOI 10.1007/s00120-023-02110-8
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  3. Article: Correction: Goodman et al. Human Papillomavirus Vaccine Impact and Effectiveness in Six High-Risk Populations: A Systematic Literature Review.

    Goodman, Elizabeth / Reuschenbach, Miriam / Kaminski, Allysen / Ronnebaum, Sarah

    Vaccines

    2023  Volume 11, Issue 7

    Abstract: The authors wish to make the following corrections to this paper [ ... ]. ...

    Abstract The authors wish to make the following corrections to this paper [...].
    Language English
    Publishing date 2023-07-11
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines11071227
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  4. Article: Human Papillomavirus Vaccine Impact and Effectiveness in Six High-Risk Populations: A Systematic Literature Review.

    Goodman, Elizabeth / Reuschenbach, Miriam / Kaminski, Allysen / Ronnebaum, Sarah

    Vaccines

    2022  Volume 10, Issue 9

    Abstract: Specific adult populations known to be at high risk for human papillomavirus (HPV)-related disease, such as men who have sex with men, are inconsistently included in national immunization programs. No compilation of the evidence on the real-world impact ... ...

    Abstract Specific adult populations known to be at high risk for human papillomavirus (HPV)-related disease, such as men who have sex with men, are inconsistently included in national immunization programs. No compilation of the evidence on the real-world impact and effectiveness of HPV vaccines across these populations exists. This systematic literature review identifies and synthesizes the evidence of the real-world impact and effectiveness of the quadrivalent and nonavalent HPV vaccines in high-risk populations: women with prior/current HPV-related anogenital disease, men who have sex with men, immunocompromised/immunosuppressed individuals, female sex workers, transgender and non-binary individuals, and patients with recurrent respiratory papillomatosis (RRP). The outcomes included anogenital precancers/cancers, head and neck cancers, genital warts, and RRP recurrence. From the 2216 records identified, 30 studies (25 effectiveness and 5 impact studies) were included in this systematic literature review. The results, quantity, and quality of these studies were highly variable. The evidence for effectiveness was of high quality only in women with prior/current cervical disease and in individuals with RRP, the most frequently studied populations. No studies of transgender/non-binary individuals or female sex workers were identified. The real-world evidence supports HPV vaccination among women with prior cervical disease and individuals with RRP. Significant real-world data gaps remain in these high-risk populations.
    Language English
    Publishing date 2022-09-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10091543
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  5. Article: Die generalistische Pflegeausbildung in Deutschland aus Sicht Auszubildender.

    Olden, Daria / Großmann, Daniel / Dorin, Lena / Meng, Michael / Peters, Miriam / Reuschenbach, Bernd

    Pflege

    2023  Volume 36, Issue 5, Page(s) 249–257

    Abstract: Students' perspective on generalized nursing education in Germany: Results of a nationwide online ... ...

    Title translation Students' perspective on generalized nursing education in Germany: Results of a nationwide online survey.
    Abstract Students' perspective on generalized nursing education in Germany: Results of a nationwide online survey
    MeSH term(s) Humans ; Education, Nursing, Baccalaureate/methods ; Students, Nursing ; Education, Nursing ; Surveys and Questionnaires ; Learning
    Language German
    Publishing date 2023-01-25
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 645005-2
    ISSN 1664-283X ; 1012-5302
    ISSN (online) 1664-283X
    ISSN 1012-5302
    DOI 10.1024/1012-5302/a000930
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    Zs.A 2399: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Primärqualifizierende Pflegestudiengänge aus Sicht Studierender.

    Großmann, Daniel / Olden, Daria / Dorin, Lena / Meng, Michael / Peters, Miriam / Reuschenbach, Bernd

    Pflege

    2022  Volume 36, Issue 4, Page(s) 209–219

    Abstract: German nursing study programs from the students' perspective: First results of a nationwide longitudinal ... ...

    Title translation German nursing study programs from the students' perspective: First results of a nationwide longitudinal study.
    Abstract German nursing study programs from the students' perspective: First results of a nationwide longitudinal study
    MeSH term(s) Humans ; Longitudinal Studies ; Education, Nursing/methods ; Learning ; Curriculum ; Students, Nursing ; Surveys and Questionnaires ; Education, Nursing, Baccalaureate/methods
    Language German
    Publishing date 2022-05-19
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 645005-2
    ISSN 1664-283X ; 1012-5302
    ISSN (online) 1664-283X
    ISSN 1012-5302
    DOI 10.1024/1012-5302/a000886
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2399: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Uptake of HPV vaccination among boys after the introduction of gender-neutral HPV vaccination in Germany before and during the COVID-19 pandemic.

    Wähner, Cornelia / Hübner, Johannes / Meisel, Dörte / Schelling, Jörg / Zingel, Rebecca / Mihm, Sarah / Wölle, Regine / Reuschenbach, Miriam

    Infection

    2023  Volume 51, Issue 5, Page(s) 1293–1304

    Abstract: Background: HPV vaccination has been recommended and reimbursed for girls in Germany since 2007. In June 2018 the German Standing Committee on Vaccination (STIKO) recommended the gender-neutral vaccination of adolescents aged 9 to 14 years with catch-up ...

    Abstract Background: HPV vaccination has been recommended and reimbursed for girls in Germany since 2007. In June 2018 the German Standing Committee on Vaccination (STIKO) recommended the gender-neutral vaccination of adolescents aged 9 to 14 years with catch-up through age 17. Objectives of this study were to describe the uptake of vaccination in boys before and during the COVID-19 pandemic.
    Methods: The study used data from a proprietary electronic medical record database and a database with information on nationally dispensed vaccine doses. The monthly number of first doses of HPV vaccinations in boys and girls aged 9-17 years in the period from 01/2018 to 12/2021 was determined. In addition, for boys the cumulative vaccination rates were calculated for initiated and completed vaccination series.
    Results: Four months after the introduction of mandatory reimbursement for boys, the monthly numbers of first doses were comparable to that of girls. Compared to the same month in 2019, the number of first doses declined by up to 49% (girls) in 2020 and 71% (boys) in 2021. At the end of 2021, the vaccination rate for 15-year-old boys (2006 birth cohort) reached 44.4% for initiated and 26.4% for completed series.
    Conclusion: After an initial dynamic increase in HPV vaccinations in boys, the impact of COVID-19 was particularly strong in the second year of the pandemic. At the end of 2021 vaccination rates were still low. Efforts are needed to catch-up on adolescents that missed doses during the pandemic and to increase uptake.
    MeSH term(s) Male ; Adolescent ; Female ; Humans ; Pandemics ; Papillomavirus Infections/epidemiology ; Papillomavirus Infections/prevention & control ; COVID-19/epidemiology ; COVID-19/prevention & control ; Papillomavirus Vaccines ; Vaccination ; Germany/epidemiology
    Chemical Substances Papillomavirus Vaccines
    Language English
    Publishing date 2023-02-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 185104-4
    ISSN 1439-0973 ; 0300-8126 ; 0173-2129
    ISSN (online) 1439-0973
    ISSN 0300-8126 ; 0173-2129
    DOI 10.1007/s15010-023-01978-0
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    Zs.A 881: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 528: Show issues

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  8. Article ; Online: Prophylactic HPV vaccines in patients with HPV-associated diseases and cancer.

    Reuschenbach, Miriam / Doorbar, John / Del Pino, Marta / Joura, Elmar A / Walker, Caroline / Drury, Rosybel / Rauscher, Andreas / Saah, Alfred J

    Vaccine

    2023  Volume 41, Issue 42, Page(s) 6194–6205

    Abstract: Individuals with human papillomavirus (HPV)-related disease remain at risk for subsequent HPV infection and related disease after treatment of specific lesions. Prophylactic HPV vaccines have shown benefits in preventing subsequent HPV-related disease ... ...

    Abstract Individuals with human papillomavirus (HPV)-related disease remain at risk for subsequent HPV infection and related disease after treatment of specific lesions. Prophylactic HPV vaccines have shown benefits in preventing subsequent HPV-related disease when administered before or soon after treatment. Based on our understanding of the HPV life cycle and vaccine mechanism of action, prophylactic HPV vaccination is not expected to clear active persistent HPV infection or unresected HPV-associated dysplastic tissue remaining after surgery. However, vaccination may reasonably be expected to prevent new HPV infections caused by a different HPV type as well as re-infection with the same HPV type, whether from a new exposure to an infected partner or through autoinoculation from an adjacent or distant productively infected site. In this review, we describe the evidence for using prophylactic HPV vaccines in patients with HPV-associated disease before, during, or after treatment and discuss potential mechanisms by which individuals with HPV-associated disease may or may not benefit from prophylactic vaccines. We also consider how precise terminology relating to the use of prophylactic vaccines in this population is critical to avoid the incorrect implication that prophylactic vaccines have direct therapeutic potential, which would be counter to the vaccine's mechanism of action, as well as considered off-label. In other words, the observed effects occur through the known mechanism of action of prophylactic HPV vaccines, namely by preventing virus of the same or a different HPV type from infecting the patient after the procedure.
    MeSH term(s) Female ; Humans ; Papillomavirus Vaccines ; Papillomavirus Infections/complications ; Papillomavirus Infections/prevention & control ; Papillomavirus Infections/epidemiology ; Uterine Cervical Neoplasms ; Human Papillomavirus Viruses ; Vaccination
    Chemical Substances Papillomavirus Vaccines
    Language English
    Publishing date 2023-09-12
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.08.047
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    Zs.A 1930: Show issues Location:
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    Zs.MO 458: Show issues

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  9. Article ; Online: Healthcare Costs and Resource Use Associated With Cervical Intraepithelial Neoplasia and Cervical Conization: A Retrospective Study of German Statutory Health Insurance Claims Data.

    Stephan, Anna-Janina / Reuschenbach, Miriam / Saxena, Kunal / Prabhu, Vimalanand S / Jacob, Christian / Schneider, Kim M / Greiner, Wolfgang / Wölle, Regine / Hampl, Monika

    Journal of health economics and outcomes research

    2022  Volume 9, Issue 1, Page(s) 128–139

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-05-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2746906-2
    ISSN 2327-2236 ; 2327-2236
    ISSN (online) 2327-2236
    ISSN 2327-2236
    DOI 10.36469/001c.35329
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  10. Article ; Online: Burden of CIN2+ diagnoses and conizations in women aged 18-45 years-a retrospective secondary data analysis of German statutory health insurance claims data.

    Reuschenbach, Miriam / Stephan, Anna-Janina / Saxena, Kunal / Prabhu, Vimalanand S / Jacob, Christian / Schneider, Kim Maren / Greiner, Wolfgang / Wölle, Regine / Hampl, Monika

    Archives of gynecology and obstetrics

    2022  Volume 306, Issue 6, Page(s) 2077–2092

    Abstract: Purpose: High grade cervical intraepithelial neoplasia (CIN2+) may progress to cervical cancer. They may be detected by screening and are usually treated by conization. This study aimed at assessing annual proportions of screening, prevalent and ... ...

    Abstract Purpose: High grade cervical intraepithelial neoplasia (CIN2+) may progress to cervical cancer. They may be detected by screening and are usually treated by conization. This study aimed at assessing annual proportions of screening, prevalent and incident CIN2+ diagnoses, as well as proportions of (re-)conizations during 24 months follow-up after conization in Germany.
    Methods: A descriptive retrospective claims data analysis of the years 2013-2018 was conducted using the InGef Research Database. Women aged 18-45 years with CIN2+ diagnoses were identified by ICD-10-GM codes (N87.1, N87.2, D06.-, and C53.-). Cervical conizations were identified by OPS codes (5-671.0* or 5-671.1*). Screening participation was identified by EBM codes (01730, 01733, 32819 or 32820). Annual proportions were calculated as women with the respective documented codes divided by all women in the respective age group per calendar year.
    Results: Overall annual proportions of screened women spanned from 60.01 to 61.33% between 2013 and 2018. The overall annual prevalence of CIN2+ diagnoses (regardless of screening participation) ranged from 0.72 to 0.84% between 2013 and 2018, with highest proportions observed in women aged 27-45 years. Also, CIN2+ incidence was highest in women 27-45 years. Annual proportion of women undergoing conization was 0.24% in 2013 and 0.21% in 2018. During a 24-month follow-up period after conization, 2.91% of women underwent a re-conization 3 months or later after the initial conization.
    Conclusion: This analysis demonstrates a considerable burden of CIN2+, conizations and re-conizations in Germany, especially in women aged 27-45 years. This highlights the need for intensified prevention efforts such as expanding human papillomavirus (HPV) vaccination.
    MeSH term(s) Female ; Humans ; Conization ; Retrospective Studies ; Data Analysis ; Papillomavirus Infections ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/epidemiology ; Uterine Cervical Neoplasms/surgery ; Insurance, Health ; Papillomaviridae
    Language English
    Publishing date 2022-04-14
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-022-06548-7
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