LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 32466

Search options

  1. Article ; Online: University of Miami Leonard M. Miller School of Medicine.

    Mechaber, Alex J / Deshpande, Amar R / Agarwal, Gauri G / Imm, Matthew / van Zuilen, Rose Maria / Lichtstein, Daniel M / Issenberg, S Barry / Gardner, Laurence B

    Academic medicine : journal of the Association of American Medical Colleges

    2021  Volume 95, Issue 9S A Snapshot of Medical Student Education in the United States and Canada: Reports From 145 Schools, Page(s) S123–S127

    Language English
    Publishing date 2021-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 96192-9
    ISSN 1938-808X ; 1040-2446
    ISSN (online) 1938-808X
    ISSN 1040-2446
    DOI 10.1097/ACM.0000000000003459
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 112: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book: Brenner & Rector's the kidney / 2 / Barry M. Brenner

    Rector, Floyd C. / Brenner, Barry M.

    2008  

    Author's details ed. by Barry M. Brenner
    Collection Brenner & Rector's the kidney
    Language English
    Size XXII S., S. 1147 - 2241, LXIX S. : Ill., graph. Darst.
    Edition 8. ed.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015378123
    ISBN 978-1-416-03105-5 ; 1-416-03105-7
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 8396 order for loan Magazin
    2008 A 1267 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book: Brenner & Rector's the kidney / 1 / Barry M. Brenner

    Rector, Floyd C. / Brenner, Barry M.

    2008  

    Author's details ed. by Barry M. Brenner
    Collection Brenner & Rector's the kidney
    Language English
    Size XXII, 1146, LIXI S. : Ill., graph. Darst.
    Edition 8. ed.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015378111
    ISBN 978-1-416-03105-5 ; 1-416-03105-7
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 8395 order for loan Magazin
    2008 A 1266 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: A Novel Tool to Identify Bactericidal Compounds against Vulnerable Targets in Drug-Tolerant M. tuberculosis found in Caseum.

    Sarathy, Jansy P / Xie, Min / Jones, Richard M / Chang, Adrienne / Osiecki, Paulina / Weiner, Danielle / Tsao, Wen-Shan / Dougher, Maureen / Blanc, Landry / Fotouhi, Nader / Via, Laura E / Barry, Clifton E / De Vlaminck, Iwijn / Sherman, David R / Dartois, Véronique A

    mBio

    2023  Volume 14, Issue 2, Page(s) e0059823

    Abstract: Caseous necrosis is a hallmark of tuberculosis (TB) pathology and creates a niche for drug-tolerant persisters within the host. Cavitary TB and high bacterial burden in caseum require longer treatment duration. ... ...

    Abstract Caseous necrosis is a hallmark of tuberculosis (TB) pathology and creates a niche for drug-tolerant persisters within the host. Cavitary TB and high bacterial burden in caseum require longer treatment duration. An
    MeSH term(s) Animals ; Mycobacterium tuberculosis/genetics ; Antitubercular Agents/pharmacology ; Antitubercular Agents/therapeutic use ; Tuberculosis/drug therapy ; Tuberculosis/microbiology ; Tuberculosis, Multidrug-Resistant ; Lipids
    Chemical Substances Antitubercular Agents ; Lipids
    Language English
    Publishing date 2023-04-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mbio.00598-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Prevalence and risk factors of M tuberculosis infection in young people across 14 communities in Zambia and South Africa.

    Amofa-Sekyi, Modupe / Schaap, Ab / Mureithi, Linda / Kosloff, Barry / Cheeba, Maina / Kangololo, Bxyn / Vermaak, Redwaan / Paulsen, Robynn / Ruperez, Maria / Floyd, Sian / de Haas, Petra / Fidler, Sarah / Hayes, Richard / Ayles, Helen / Shanaube, Kwame

    PLOS global public health

    2023  Volume 3, Issue 9, Page(s) e0002077

    Abstract: ... communities. We describe the baseline prevalence and risk factors of Mycobacterium tuberculosis (M ... TB Gold Plus assay (QFT-Plus) was used to detect M. tuberculosis infection, following manufacturer's ...

    Abstract Background: From 2018-2021 the TB Reduction through Expanded Antiretroviral Treatment and TB Screening (TREATS) project took place in 21 Zambian and South African communities. The TREATS Incidence of TB Infection Cohort Study was conducted in adolescents and young people (AYP), aged 15-24 years in 14 communities. We describe the baseline prevalence and risk factors of Mycobacterium tuberculosis (M. tuberculosis) infection among this cohort and explore the quantitative QFT-Plus interferon gamma (IFN-γ) responses.
    Methods and findings: A random sample of approximately 300 AYP per community were recruited and information on TB/HIV risk factors, TB symptoms and social mixing patterns collected. QuantiFERON TB Gold Plus assay (QFT-Plus) was used to detect M. tuberculosis infection, following manufacturer's instructions. Logistic regression was used to determine factors associated with infection. 5577 eligible AYP were invited to participate across both countries, with 4648 enrolled. QFT-Plus results were available for 4529: 2552(Zambia) and 1977(South Africa). Overall, 47.6% (2156/4529) AYP had positive QFT-Plus results, the prevalence of infection in South Africa being twice that in Zambia (64.7% (1280/1977) vs 34.3% (867/2552) p<0.001). Infection was associated with age, household contact with TB and alcohol in Zambia but showed no associations in South Africa. The antigen tube differential (TB2-TB1>0.6 IU/ml) of the assay at baseline showed no evidence of association with recent TB exposure.
    Conclusion: The high prevalence of infection in AYP warrants urgent action to address TB control, especially in South Africa. Further research is required to delineate antigen tube responses of the QFT-Plus assay more precisely to fully realise the benefit of the additional TB2 tube in high TB/HIV burden settings.
    Language English
    Publishing date 2023-09-29
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3375
    ISSN (online) 2767-3375
    DOI 10.1371/journal.pgph.0002077
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Book: The M. D. Anderson surgical oncology handbook

    Feig, Barry W. / Ching, C. Denise

    (A Lippincott Williams & Wilkins handbook)

    2012  

    Title variant Surgical oncology handbook ; The MD Anderson surgical oncology handbook
    Institution M. D. Anderson Cancer Center / Department of Surgical Oncology
    Author's details ed. Barry W. Feig ; C. Denise Ching
    Series title A Lippincott Williams & Wilkins handbook
    Keywords Neoplasms / surgery
    Language English
    Size XX, 900 S. : Ill., graph. Darst.
    Edition 5. ed.
    Publisher Wolters Kluwer Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT017319397
    ISBN 978-1-60831-284-9 ; 1-60831-284-4
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 3380 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book ; Online: The M.D. Anderson surgical oncology handbook

    Feig, Barry W., 1959- / Berger, David H., 1959- / Fuhrman, George M.

    2006  

    Title variant Surgical oncology handbook
    Institution University of Texas M.D. Anderson Cancer Center. Department of Surgical Oncology
    Author's details editors, Barry W. Feig, David H. Berger, George M. Fuhrman
    Keywords Neoplasms - surgery ; Handbooks
    Language English
    Size 1 Online-Ressource (xii, 707 Seiten), Illustrationen
    Edition 4th ed.
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia
    Document type Book ; Online
    Note Includes bibliographical references and index
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 978-0-7817-5643-3 ; 0-7817-5643-X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book: Brenner & Rector's the kidney / 1 / Barry M. Brenner

    Rector, Floyd C. / Brenner, Barry M.

    2004  

    Author's details ed. by Barry M. Brenner
    Collection Brenner & Rector's the kidney
    Language English
    Size XXI, 1481, LXXII S. : Ill., graph. Darst.
    Edition 7. ed.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT013843212
    ISBN 0-7216-0164-2 ; 978-0-7216-0164-9
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 300 order for loan Magazin
    2008 A 3197 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Book: Brenner & Rector's the kidney / 2 / Barry M. Brenner

    Rector, Floyd C. / Brenner, Barry M.

    2004  

    Author's details ed. by Barry M. Brenner
    Collection Brenner & Rector's the kidney
    Language English
    Size XXI S., S. 1484 - 2870, LXXII S. : Ill., graph. Darst.
    Edition 7. ed.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    Note Systemvoraussetzungen: Minimum system requirements: Windows: Windows 98, 2000, ME, NT4 (Service Pack 3 and above), or XP operating system; Microsoft Internet Explorer v5 (or later), or Netscape Navigator v4.8 (or later); Adobe Acrobat Reader 4.05 (or later); 800x600-pixel screen resolution; 16-bit color (65000 colors); 64 MB of RAM. Macintosh: MAC OS 9 (or later), or MAC OS X with classic Enviroments operating system; Microsoft Internet Explorer v5 (or later), or Netscape Navigator v4.8 (or later); Adobe Acrobat Reader 4.05 (or later); 800x600-pixel screen resolution; 16-bit color (65000 colors); 64 MB of RAM
    Accompanying material 1 CD-ROM (12 cm) + Begleith. (7 S.)
    HBZ-ID HT013843217
    ISBN 0-7216-0164-2 ; 978-0-7216-0164-9
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 301 order for loan Magazin
    2004 MO 49 <<[Begleitmaterial]>> order for loan Magazin
    2004 MO 50 <<[Begleitmaterial]>> order for loan Magazin
    2008 A 3198 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Hepatic FoxOs link insulin signaling with plasma lipoprotein metabolism through an apolipoprotein M/sphingosine-1-phosphate pathway.

    Izquierdo, María Concepción / Shanmugarajah, Niroshan / Lee, Samuel X / Kraakman, Michael J / Westerterp, Marit / Kitamoto, Takumi / Harris, Michael / Cook, Joshua R / Gusarova, Galina A / Zhong, Kendra / Marbuary, Elijah / O-Sullivan, InSug / Rasmus, Nikolaus / Camastra, Stefania / Unterman, Terry G / Ferrannini, Ele / Hurwitz, Barry E / Haeusler, Rebecca A

    The Journal of clinical investigation

    2022  Volume 132, Issue 7

    Abstract: ... associates with HDL by binding to apolipoprotein M (ApoM). Insulin resistance is a major driver ...

    Abstract Multiple beneficial cardiovascular effects of HDL depend on sphingosine-1-phosphate (S1P). S1P associates with HDL by binding to apolipoprotein M (ApoM). Insulin resistance is a major driver of dyslipidemia and cardiovascular risk. However, the mechanisms linking alterations in insulin signaling with plasma lipoprotein metabolism are incompletely understood. The insulin-repressible FoxO transcription factors mediate key effects of hepatic insulin action on glucose and lipoprotein metabolism. This work tested whether hepatic insulin signaling regulates HDL-S1P and aimed to identify the underlying molecular mechanisms. We report that insulin-resistant, nondiabetic individuals had decreased HDL-S1P levels, but no change in total plasma S1P. This also occurred in insulin-resistant db/db mice, which had low ApoM and a specific reduction of S1P in the HDL fraction, with no change in total plasma S1P levels. Using mice lacking hepatic FoxOs (L-FoxO1,3,4), we found that hepatic FoxOs were required for ApoM expression. Total plasma S1P levels were similar to those in controls, but S1P was nearly absent from HDL and was instead increased in the lipoprotein-depleted plasma fraction. This phenotype was restored to normal by rescuing ApoM in L-FoxO1,3,4 mice. Our findings show that insulin resistance in humans and mice is associated with decreased HDL-associated S1P. Our study shows that hepatic FoxO transcription factors are regulators of the ApoM/S1P pathway.
    MeSH term(s) Animals ; Apolipoproteins M/genetics ; Apolipoproteins M/metabolism ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; Insulin/metabolism ; Lipoproteins, HDL/metabolism ; Liver/metabolism ; Lysophospholipids/metabolism ; Mice ; Sphingosine/analogs & derivatives ; Sphingosine/metabolism
    Chemical Substances ApoM protein, mouse ; Apolipoproteins M ; Forkhead Transcription Factors ; Insulin ; Lipoproteins, HDL ; Lysophospholipids ; sphingosine 1-phosphate (26993-30-6) ; Sphingosine (NGZ37HRE42)
    Language English
    Publishing date 2022-02-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 3067-3
    ISSN 1558-8238 ; 0021-9738
    ISSN (online) 1558-8238
    ISSN 0021-9738
    DOI 10.1172/JCI146219
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.184: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top