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  1. Article ; Online: Recommendations for Deferred Testing in Low-Risk Chest Pain-Decades Old But Now Finally Tested.

    Gibbons, Raymond J

    JAMA cardiology

    2023  Volume 8, Issue 10, Page(s) 924–926

    MeSH term(s) Humans ; Chest Pain/diagnosis ; Chest Pain/etiology ; Risk
    Language English
    Publishing date 2023-08-22
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2023.2715
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: CT or Invasive Coronary Angiography in Stable Chest Pain.

    Gibbons, Raymond J

    The New England journal of medicine

    2022  Volume 387, Issue 4, Page(s) 378

    MeSH term(s) Chest Pain/diagnostic imaging ; Chest Pain/etiology ; Coronary Angiography ; Coronary Artery Disease/complications ; Coronary Artery Disease/diagnostic imaging ; Humans ; Tomography, X-Ray Computed
    Language English
    Publishing date 2022-08-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2206973
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  3. Article ; Online: Consistency and Generalizability of Trials for Coronary Computed Tomography Angiography-Reply.

    Gibbons, Raymond J

    JAMA cardiology

    2020  

    Language English
    Publishing date 2020-12-23
    Publishing country United States
    Document type Journal Article
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2020.6133
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  4. Article ; Online: Myocardial Ischemia in the Management of Chronic Coronary Artery Disease: Past and Present.

    Gibbons, Raymond J

    Circulation. Cardiovascular imaging

    2021  Volume 14, Issue 1, Page(s) e011615

    Abstract: For many years, stress-induced myocardial ischemia has been considered important in the management of chronic coronary artery disease. Early evidence focused on the exercise ECG and the Duke treadmill score. In the 1970s, randomized clinical trials, ... ...

    Abstract For many years, stress-induced myocardial ischemia has been considered important in the management of chronic coronary artery disease. Early evidence focused on the exercise ECG and the Duke treadmill score. In the 1970s, randomized clinical trials, which compared coronary artery bypass surgery to medical therapy, enrolled patients who were very different from contemporary practice and had inconsistent results. Surgery appeared to be of greatest benefit in high-risk patients defined by anatomy (such as left main disease) or stress-induced ischemia. However, randomized clinical trials of revascularization versus contemporary medical therapy over the past 20 years have been surprisingly negative. Nuclear cardiology substudies from these trials reported inconsistent results. Two observational studies from a single-center provided the best evidence for the use of stress-induced ischemia to identify patients who were most likely to benefit from revascularization. The recently completed ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) was designed to test the hypothesis that revascularization would improve outcomes in patients with moderate-severe ischemia on stress testing. Unfortunately, 14.2% of the randomized patients had either mild or no ischemia on core lab review. Nearly one-quarter of the patients were randomized on the basis of an exercise ECG without imaging. The negative results of the trial reflect the long-term population decline in coronary artery disease and abnormal stress tests, as well as improvements in patient outcome due to optimal medical therapy. Topics requiring further research are presented. The implications of the trial for the use of both stress imaging and coronary computed tomography angiography in clinical practice are examined.
    MeSH term(s) Chronic Disease ; Coronary Angiography ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/surgery ; Exercise Test/methods ; Humans ; Myocardial Ischemia/diagnosis ; Myocardial Ischemia/surgery ; Myocardial Revascularization/methods ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-01-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2435045-X
    ISSN 1942-0080 ; 1941-9651
    ISSN (online) 1942-0080
    ISSN 1941-9651
    DOI 10.1161/CIRCIMAGING.120.011615
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Does Every Patient With Stable Chest Pain Need Coronary Computed Tomography Angiography, Usually After a Standard Stress Electrocardiogram?

    Gibbons, Raymond J

    JAMA cardiology

    2020  Volume 5, Issue 8, Page(s) 862–863

    MeSH term(s) Chest Pain/diagnosis ; Chest Pain/etiology ; Computed Tomography Angiography ; Coronary Angiography ; Coronary Disease/diagnosis ; Coronary Disease/diagnostic imaging ; Electrocardiography/standards ; Exercise Test/standards ; Humans
    Language English
    Publishing date 2020-06-01
    Publishing country United States
    Document type Journal Article
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2020.1579
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  6. Article ; Online: Is the Search for Enough Moderate-Severe Ischemia Nearly Over?

    Gibbons, Raymond J

    JAMA cardiology

    2019  Volume 4, Issue 3, Page(s) 203–205

    MeSH term(s) Humans ; Ischemia
    Language English
    Publishing date 2019-02-27
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2019.0024
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  7. Article ; Online: Predictors of inducible ischemia with radionuclide stress testing: Choosing the right patients when the patients are changing.

    Jouni, Hayan / Gibbons, Raymond J

    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

    2021  Volume 29, Issue 6, Page(s) 2850–2852

    MeSH term(s) Humans ; Myocardial Ischemia/diagnostic imaging ; Exercise Test ; Ischemia ; Radioisotopes
    Chemical Substances Radioisotopes
    Language English
    Publishing date 2021-11-24
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1212505-2
    ISSN 1532-6551 ; 1071-3581
    ISSN (online) 1532-6551
    ISSN 1071-3581
    DOI 10.1007/s12350-021-02853-x
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    Zs.A 4121: Show issues Location:
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  8. Article ; Online: Imperfect Data Can Still Provide Important Answers.

    Gibbons, Raymond J

    JACC. Cardiovascular imaging

    2018  Volume 12, Issue 8 Pt 1, Page(s) 1427–1429

    MeSH term(s) Exercise Test ; Humans ; Medicare ; Renal Insufficiency, Chronic ; United States
    Language English
    Publishing date 2018-06-13
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2491503-8
    ISSN 1876-7591 ; 1936-878X
    ISSN (online) 1876-7591
    ISSN 1936-878X
    DOI 10.1016/j.jcmg.2018.04.017
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    Zs.A 6846: Show issues Location:
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  9. Article ; Online: High-Risk Coronary Atherosclerotic Plaque Assessment by Coronary Computed Tomography Angiography-Should We Use It?

    Gibbons, Raymond J

    JAMA cardiology

    2018  Volume 3, Issue 2, Page(s) 153–154

    MeSH term(s) Chest Pain ; Computed Tomography Angiography ; Coronary Angiography ; Humans ; Plaque, Atherosclerotic ; Risk Assessment
    Language English
    Publishing date 2018-01-10
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2017.5016
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  10. Article ; Online: Declining Accuracy of the Traditional Diamond-Forrester Estimates of Pretest Probability of Coronary Artery Disease: Time for New Methods.

    Gibbons, Raymond J / Miller, Todd D

    JAMA internal medicine

    2021  Volume 181, Issue 5, Page(s) 579–580

    MeSH term(s) Area Under Curve ; Coronary Angiography/methods ; Coronary Angiography/standards ; Coronary Angiography/statistics & numerical data ; Coronary Artery Disease/complications ; Coronary Artery Disease/epidemiology ; Coronary Artery Disease/mortality ; Humans ; Prognosis ; ROC Curve ; Risk Assessment/methods ; Risk Assessment/standards ; Risk Assessment/trends ; Sensitivity and Specificity
    Language English
    Publishing date 2021-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2021.0171
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