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  1. Article ; Online: Propensity score matching is needed to evaluate the clinical success rate of peroral endoscopic myotomy.

    Zhou, Yangyang / Guo, Qihang / Zheng, Shimeng / Li, Deliang

    Gastrointestinal endoscopy

    2024  Volume 99, Issue 4, Page(s) 660

    MeSH term(s) Humans ; Propensity Score ; Esophagoscopy ; Esophageal Achalasia/surgery ; Digestive System Surgical Procedures ; Myotomy ; Treatment Outcome ; Natural Orifice Endoscopic Surgery ; Esophageal Sphincter, Lower/surgery
    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Letter
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2023.10.045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 283: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 519: Show issues

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  2. Article: Preparation of a novel poly-(di-ionic liquid)/BDD-modified electrode for the detection of tetrachloro-

    Guo, Yanni / He, Deliang

    Journal of molecular liquids

    2023  Volume 385, Page(s) 122242

    Abstract: During the COVID-19 pandemic, the release of toxic disinfection by-products (DBPs) has increased due to the intensive, large-scale use of disinfectants. Halogenated benzoquinones (HBQs) are among the most toxic DBPs, but there is no rapid, convenient, ... ...

    Abstract During the COVID-19 pandemic, the release of toxic disinfection by-products (DBPs) has increased due to the intensive, large-scale use of disinfectants. Halogenated benzoquinones (HBQs) are among the most toxic DBPs, but there is no rapid, convenient, and economical detection method. In this study, a novel PDIL/BDD-modified electrode was prepared in a mixed solvent of dimethyl sulfoxide (DMSO) and acetonitrile (ACN) by electrochemical polymerization with a di-ionic ionic liquid containing alkenyl groups as the monomer. The electrochemical behavior of tetra-chloro-
    Language English
    Publishing date 2023-06-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491496-7
    ISSN 1873-3166 ; 0167-7322
    ISSN (online) 1873-3166
    ISSN 0167-7322
    DOI 10.1016/j.molliq.2023.122242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: SREBF1/SREBP-1 concurrently regulates lipid synthesis and lipophagy to maintain lipid homeostasis and tumor growth.

    Geng, Feng / Guo, Deliang

    Autophagy

    2023  , Page(s) 1–3

    Abstract: Cholesterol is an essential structural component of the cell membrane, whereas excess cholesterol can be toxic and thus is stored in intracellular lipid droplets (LDs). Malignant tumor cells grow rapidly and require abundant cholesterol to build new ... ...

    Abstract Cholesterol is an essential structural component of the cell membrane, whereas excess cholesterol can be toxic and thus is stored in intracellular lipid droplets (LDs). Malignant tumor cells grow rapidly and require abundant cholesterol to build new membranes. How they maintain cholesterol homeostasis is largely unknown. We recently revealed that SREBF1/SREBP-1 (sterol regulatory element binding transcription factor 1), a key lipogenic transcription factor, plays a critical role in maintaining cholesterol homeostasis in tumor cells. We found that in addition to activation of
    Language English
    Publishing date 2023-11-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2454135-7
    ISSN 1554-8635 ; 1554-8627
    ISSN (online) 1554-8635
    ISSN 1554-8627
    DOI 10.1080/15548627.2023.2275501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6741: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  4. Article ; Online: Glutamine-released ammonia acts as an unprecedented signaling molecule activating lipid production.

    Cheng, Chunming / Kelsey, Scott / Guo, Deliang

    Genes & diseases

    2022  Volume 10, Issue 2, Page(s) 307–309

    Language English
    Publishing date 2022-08-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2821806-1
    ISSN 2352-3042 ; 2352-3042
    ISSN (online) 2352-3042
    ISSN 2352-3042
    DOI 10.1016/j.gendis.2022.07.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Clinical Characteristics of Cancer Patients With COVID-19: A Retrospective Multicentric Study in 19 Hospitals Within Hubei, China.

    Guo, Deliang / Wang, Haitao / Zhu, Qian / Yuan, Yufeng

    Frontiers in medicine

    2021  Volume 8, Page(s) 614057

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2021-10-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2021.614057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: SCAP links glucose to lipid metabolism in cancer cells.

    Guo, Deliang

    Molecular & cellular oncology

    2016  Volume 3, Issue 2

    Abstract: We recently uncovered that glucose is a critical activator of sterol regulatory element-binding proteins (SREBPs). Glucose promotes SREBP-cleavage activating protein (SCAP)/SREBP complex trafficking from the ER to the Golgi and subsequent SREBP ... ...

    Abstract We recently uncovered that glucose is a critical activator of sterol regulatory element-binding proteins (SREBPs). Glucose promotes SREBP-cleavage activating protein (SCAP)/SREBP complex trafficking from the ER to the Golgi and subsequent SREBP activation via N-glycosylation of SCAP. Our study also demonstrated that SCAP plays a critical role in tumor growth.
    Language English
    Publishing date 2016-01-08
    Publishing country United States
    Document type Journal Article
    ISSN 2372-3556
    ISSN 2372-3556
    DOI 10.1080/23723556.2015.1132120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Distribution and bioavailability of mercury in size-fractioned atmospheric particles around an ultra-low emission power plant in Southwest China

    Zhang, Wei / Li, Jinjuan / Qiu, Hao / Guo, Xingqiang / Fei, Zhijun / Xing, Yi / Yin, Deliang

    Journal of Environmental Sciences. 2024 Apr., v. 138 p.141-152

    2024  

    Abstract: Ultra-low emission (ULE) technology retrofits significantly impact the particulate-bound mercury (Hg) emissions from coal-fired power plants (CFPPs); however, the distribution and bioavailability of Hg in size-fractioned particulate matter (PM) around ... ...

    Abstract Ultra-low emission (ULE) technology retrofits significantly impact the particulate-bound mercury (Hg) emissions from coal-fired power plants (CFPPs); however, the distribution and bioavailability of Hg in size-fractioned particulate matter (PM) around the ULE-retrofitted CFPPs are less understood. Here, total Hg and its chemical speciation in TSP (total suspended particles), PM₁₀ (aerodynamic particle diameter ≤ 10 µm) and PM₂.₅ (aerodynamic particle diameter ≤ 2.5 µm) around a ULE-retrofitted CFPP in Guizhou Province were quantified. Atmospheric PM₂.₅ concentration was higher around this ULE-retrofitted CFPP than that in the intra-regional urban cities, and it had higher mass Hg concentration than other size-fractioned PM. Total Hg concentrations in PM had multifarious sources including CFPP, vehicle exhaust and biomass combustion, while they were significantly higher in autumn and winter than those in other seasons (P < 0.05). Regardless of particulate size, atmospheric PM-bound Hg had lower residual fractions (< 21%) while higher HCl-soluble fractions (> 40%). Mass concentrations of exchangeable, HCl-soluble, elemental, and residual Hg in PM₂.₅ were higher than those in other size-fractioned PM, and were markedly elevated in autumn and winter (P < 0.05). In PM₂.₅, HCl-soluble Hg presented a significantly positive relationship with elemental Hg (P < 0.05), while residual Hg showed the significantly positive relationships with HCl-soluble Hg and elemental Hg (P < 0.01). Overall, these results suggested that atmospheric PM-bound Hg around the ULE-retrofitted CFPP tends to accumulate in finer PM, and has higher bioavailable fractions, while has potential transformation between chemical speciation.
    Keywords aerodynamics ; autumn ; bioavailability ; biomass ; chemical speciation ; coal ; combustion ; mercury ; particle size ; particulates ; power plants ; winter ; China ; Size-fractioned particles ; Coal-fired power plant ; Ultra-low emission
    Language English
    Dates of publication 2024-04
    Size p. 141-152.
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 1092300-7
    ISSN 1878-7320 ; 1001-0742
    ISSN (online) 1878-7320
    ISSN 1001-0742
    DOI 10.1016/j.jes.2023.03.029
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 7630: Show issues

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  8. Article: Lipid Metabolism in Glioblastoma: From De Novo Synthesis to Storage.

    Kou, Yongjun / Geng, Feng / Guo, Deliang

    Biomedicines

    2022  Volume 10, Issue 8

    Abstract: Glioblastoma (GBM) is the most lethal primary brain tumor. With limited therapeutic options, novel therapies are desperately needed. Recent studies have shown that GBM acquires large amounts of lipids for rapid growth through activation of sterol ... ...

    Abstract Glioblastoma (GBM) is the most lethal primary brain tumor. With limited therapeutic options, novel therapies are desperately needed. Recent studies have shown that GBM acquires large amounts of lipids for rapid growth through activation of sterol regulatory element-binding protein 1 (SREBP-1), a master transcription factor that regulates fatty acid and cholesterol synthesis, and cholesterol uptake. Interestingly, GBM cells divert substantial quantities of lipids into lipid droplets (LDs), a specific storage organelle for neutral lipids, to prevent lipotoxicity by increasing the expression of diacylglycerol acyltransferase 1 (DGAT1) and sterol-O-acyltransferase 1 (SOAT1), which convert excess fatty acids and cholesterol to triacylglycerol and cholesteryl esters, respectively. In this review, we will summarize recent progress on our understanding of lipid metabolism regulation in GBM to promote tumor growth and discuss novel strategies to specifically induce lipotoxicity to tumor cells through disrupting lipid storage, a promising new avenue for treating GBM.
    Language English
    Publishing date 2022-08-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines10081943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Mixed Neuroendocrine Carcinoma and Hepatocellular Carcinoma: A Case Report and Literature Review.

    Lan, Jianwei / Guo, Deliang / Qin, Xian / Chen, Baiyang / Liu, Quanyan

    Frontiers in surgery

    2021  Volume 8, Page(s) 678853

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-07-14
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2021.678853
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Distribution and bioavailability of mercury in size-fractioned atmospheric particles around an ultra-low emission power plant in Southwest China.

    Zhang, Wei / Li, Jinjuan / Qiu, Hao / Guo, Xingqiang / Fei, Zhijun / Xing, Yi / Yin, Deliang

    Journal of environmental sciences (China)

    2023  Volume 138, Page(s) 141–152

    Abstract: Ultra-low emission (ULE) technology retrofits significantly impact the particulate-bound mercury (Hg) emissions from coal-fired power plants (CFPPs); however, the distribution and bioavailability of Hg in size-fractioned particulate matter (PM) around ... ...

    Abstract Ultra-low emission (ULE) technology retrofits significantly impact the particulate-bound mercury (Hg) emissions from coal-fired power plants (CFPPs); however, the distribution and bioavailability of Hg in size-fractioned particulate matter (PM) around the ULE-retrofitted CFPPs are less understood. Here, total Hg and its chemical speciation in TSP (total suspended particles), PM
    MeSH term(s) Air Pollutants/analysis ; Mercury/analysis ; Biological Availability ; Environmental Monitoring/methods ; Particulate Matter/analysis ; Dust ; Power Plants ; China ; Coal ; Seasons ; Particle Size
    Chemical Substances Air Pollutants ; Mercury (FXS1BY2PGL) ; Particulate Matter ; Dust ; Coal
    Language English
    Publishing date 2023-04-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1092300-7
    ISSN 1878-7320 ; 1001-0742
    ISSN (online) 1878-7320
    ISSN 1001-0742
    DOI 10.1016/j.jes.2023.03.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7630: Show issues

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