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  1. Article ; Online: Impact of the gene polymorphisms in the renin-angiotensin system on cardiomyopathy risk

    Xiaoxiao Jia / Liping Meng / Weiliang Tang / Liping Sun / Fang Peng / Peng Zhang

    PLoS ONE, Vol 19, Iss

    A meta-analysis

    2024  Volume 1

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Complex Dynamics of Noise-Perturbed Excitatory-Inhibitory Neural Networks With Intra-Correlative and Inter-Independent Connections.

    Peng, Xiaoxiao / Lin, Wei

    Frontiers in physiology

    2022  Volume 13, Page(s) 915511

    Abstract: Real neural system usually contains two types of neurons, i.e., excitatory neurons and inhibitory ones. Analytical and numerical interpretation of dynamics induced by different types of interactions among the neurons of two types is beneficial to ... ...

    Abstract Real neural system usually contains two types of neurons, i.e., excitatory neurons and inhibitory ones. Analytical and numerical interpretation of dynamics induced by different types of interactions among the neurons of two types is beneficial to understanding those physiological functions of the brain. Here, we articulate a model of noise-perturbed random neural networks containing both excitatory and inhibitory (E&I) populations. Particularly, both
    Language English
    Publishing date 2022-06-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2022.915511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Investigating polymorphisms related to chronic kidney disease and the effect of health and nursing education on self-management ability and quality of life in hemodialysis patients.

    Qu, Xiaoxiao / Shen, Peng

    Cellular and molecular biology (Noisy-le-Grand, France)

    2023  Volume 69, Issue 1, Page(s) 25–29

    Abstract: The effects of health and nursing education are fundamental and essential in achieving the desired quality of life. In recent years, the impact of health and nursing education and self-management ability in many diseases, including kidney patients and ... ...

    Abstract The effects of health and nursing education are fundamental and essential in achieving the desired quality of life. In recent years, the impact of health and nursing education and self-management ability in many diseases, including kidney patients and those undergoing dialysis and hemodialysis, have been highly regarded. Studies have shown that modern nursing training and self-management ability have an influential role in the treatment process of hemodialysis patients. In general, self-management is a common term in health education and includes symptom management, treatment principles, consequences, and lifestyle changes to maintain and improve quality of life. Planning and continuity of care are necessary for self-management, and the set of these factors is an important and effective issue in kidney and hemodialysis patients and has caused hope, encouragement, and encouragement to more and more patients, improving their quality of life and correct use of healthcare services. In this study, we investigated some health management parameters in the quality of life of hemodialysis patients. The results of this study showed that family support, self-management of personnel, and the nursing system have a positive and significant correlation with the quality of life in these patients (p=0.002). This means that family and social support along with the modern nursing system and self-management can lead to an increase in the quality of life in hemodialysis patients. Also, the results of polymorphism analysis in the GATM locus related to chronic kidney disease showed that the frequency of the A allele in SNP rs2453533-GATM is higher in CKD patients independent of dialysis (non-dialysis) compared to healthy people. Also, the intronic C allele of SNP rs4293393 (UMOD) was more common in healthy subjects than in CKD patients, and the intronic T allele of SNP rs9895661 (BCAS3) is associated with a decrease in eGFRcys and eGFRcrea.
    MeSH term(s) Humans ; Quality of Life ; Self-Management ; Renal Dialysis ; Renal Insufficiency, Chronic/genetics ; Renal Insufficiency, Chronic/therapy ; Education, Nursing
    Language English
    Publishing date 2023-01-31
    Publishing country France
    Document type Journal Article
    ZDB-ID 1161779-2
    ISSN 1165-158X ; 0145-5680
    ISSN (online) 1165-158X
    ISSN 0145-5680
    DOI 10.14715/cmb/2022.69.1.5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Family Functioning and Intraindividual Reaction Time Variability Interactively Predict Children's Externalizing Problems.

    Peng, Yuan / Wang, Xiaoxiao / Hao, Yanli

    Child psychiatry and human development

    2023  

    Abstract: Family functioning including family adaptability and family cohesion, and intraindividual reaction time variability (IIV) which serves as an index of attentional control has been found to relate to children's externalizing problems. However, it remains ... ...

    Abstract Family functioning including family adaptability and family cohesion, and intraindividual reaction time variability (IIV) which serves as an index of attentional control has been found to relate to children's externalizing problems. However, it remains unknown whether family functioning interacts with children's IIV to predict their externalizing problems based on the diathesis-stress model. The present study examined this concern. Participants included 168 (M
    Language English
    Publishing date 2023-04-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 223895-0
    ISSN 1573-3327 ; 0009-398X
    ISSN (online) 1573-3327
    ISSN 0009-398X
    DOI 10.1007/s10578-023-01533-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Ewing's sarcoma of proximal femur: case report of extreme osteotomy with 3D-printed prosthesis for the reconstruction.

    Niu, Xiaoying / Tian, Wen / Liang, Xiaoxiao / Yao, Weitao / Zhang, Peng

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1248330

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-10-09
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1248330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Dihydromyricetin ameliorates oxygen‑glucose deprivation and re‑oxygenation‑induced injury in HT22 cells by activating the Wnt/β‑catenin signaling pathway.

    Tao, Xiaoxiao / Jiang, Yaping / Zheng, Xian / Ji, Xiaoxiao / Peng, Feifei

    Molecular medicine reports

    2022  Volume 25, Issue 3

    Abstract: Dihydromyricetin (DMY) is a natural flavonoid that possesses a wide range of pharmacological properties. The aim of the present study was to determine whether DMY could protect against nerve cell injury following ischemic stroke through antioxidant and ... ...

    Abstract Dihydromyricetin (DMY) is a natural flavonoid that possesses a wide range of pharmacological properties. The aim of the present study was to determine whether DMY could protect against nerve cell injury following ischemic stroke through antioxidant and neuroprotective effects. The effects of DMY on the viability, oxidative stress and apoptosis of HT22 cells following oxygen‑glucose deprivation and re‑oxygenation (OGD/R) were examined using MTT, lactate dehydrogenase (LDH), superoxide (SOD), malondialdehyde (MDA), western blot and TUNEL assays. Furthermore, Wnt/β‑catenin signaling proteins in OGD/R‑stimulated HT22 cells were detected in the presence or absence of DMY. In a separate experiment, the effect of DMY on OGD/R‑induced HT22 cell injury was also observed in the presence of the Wnt/β‑catenin inhibitor, XAV939. The results demonstrated that DMY had no impact on the survival of untreated HT22 cells, although DMY treatment significantly increased cell viability and inhibited cytotoxicity, oxidative stress and apoptosis following OGD/R. In addition, DMY upregulated the expression of Wnt/β‑catenin in OGD/R‑stimulated HT22 cells. In conclusion, DMY protected HT22 cells from OGD/R‑induced oxidative stress and apoptosis, and its effects may be mediated by the activation of the Wnt/β‑catenin signaling pathway.
    MeSH term(s) Apoptosis ; Cell Survival ; Flavonols/pharmacology ; Glucose/metabolism ; Oxidative Stress ; Oxygen/metabolism ; Wnt Signaling Pathway
    Chemical Substances Flavonols ; Glucose (IY9XDZ35W2) ; dihydromyricetin (KD8QND6427) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2022-01-28
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2469505-1
    ISSN 1791-3004 ; 1791-2997
    ISSN (online) 1791-3004
    ISSN 1791-2997
    DOI 10.3892/mmr.2022.12619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Leaf rolling precedes stomatal closure in rice (Oryza sativa) under drought conditions.

    Wang, Xiaoxiao / Huang, Jianliang / Peng, Shaobing / Xiong, Dongliang

    Journal of experimental botany

    2023  Volume 74, Issue 21, Page(s) 6650–6661

    Abstract: Leaf rolling is a physiological response to drought that may help to reduce water loss, but its significance as a contribution to drought tolerance is uncertain. We scored the leaf rolling of four rice genotypes along an experimental drought gradient ... ...

    Abstract Leaf rolling is a physiological response to drought that may help to reduce water loss, but its significance as a contribution to drought tolerance is uncertain. We scored the leaf rolling of four rice genotypes along an experimental drought gradient using an improved cryo-microscopy method. Leaf water potential (Ψleaf), gas exchange, chlorophyll fluorescence, leaf hydraulic conductance, rehydration capacity, and the bulk turgor loss point were also analysed. During the drought process, stomatal conductance declined sharply to reduce water loss, and leaves rolled up before the stomata completely closed. The leaf water loss rate of rolled leaves was significantly reduced compared with artificially flattened leaves. The Ψleaf threshold of initial leaf rolling ranged from -1.95 to -1.04 MPa across genotypes. When a leaf rolled so that the leaf edges were touching, photosynthetic rate and stomatal conductance declined more than 80%. Across genotypes, leaf hydraulic conductance declined first, followed by gas exchange and chlorophyll fluorescence parameters. However, the Ψleaf threshold for a given functional trait decline differed significantly among genotypes, with the exception of leaf hydraulic conductance. Our results suggested that leaf rolling was mechanistically linked to drought avoidance and tolerance traits and might serve as a useful phenotypic trait for rice breeding in future drought scenarios.
    MeSH term(s) Oryza/genetics ; Plant Stomata/physiology ; Droughts ; Plant Breeding ; Plant Leaves/physiology ; Water/physiology ; Chlorophyll
    Chemical Substances Water (059QF0KO0R) ; Chlorophyll (1406-65-1)
    Language English
    Publishing date 2023-08-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2976-2
    ISSN 1460-2431 ; 0022-0957
    ISSN (online) 1460-2431
    ISSN 0022-0957
    DOI 10.1093/jxb/erad316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Fe-doped V

    Peng, Xiaoxiao / Zou, Zhengguang / Ling, Wenqin / Liang, Fangan / Geng, Jing / Zhang, Shuchao / Zhong, Shenglin

    Nanotechnology

    2023  Volume 34, Issue 23

    Abstract: As a lithium-ion battery cathode material with high theoretical capacity, the application of ... ...

    Abstract As a lithium-ion battery cathode material with high theoretical capacity, the application of V
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/acbeb5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: High-MOI induces rapid CRISPR spacer acquisition in

    Bhoobalan-Chitty, Yuvaraj / Duan, Xiaoxiao / Peng, Xu

    microPublication biology

    2022  Volume 2022

    Abstract: Spacer acquisition, the first step in CRISPR-Cas adaptive immunity, plays a critical role in establishing and strengthening host defense against mobile genetic elements (MGEs). Here we present a host-virus system, where an increase in the multiplicity of ...

    Abstract Spacer acquisition, the first step in CRISPR-Cas adaptive immunity, plays a critical role in establishing and strengthening host defense against mobile genetic elements (MGEs). Here we present a host-virus system, where an increase in the multiplicity of infection (MOI), of a CRISPR-Cas susceptible virus, forces rapid spacer acquisition in the
    Language English
    Publishing date 2022-11-08
    Publishing country United States
    Document type Journal Article
    ISSN 2578-9430
    ISSN (online) 2578-9430
    DOI 10.17912/micropub.biology.000664
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Impact of the gene polymorphisms in the renin-angiotensin system on cardiomyopathy risk: A meta-analysis.

    Jia, Xiaoxiao / Meng, Liping / Tang, Weiliang / Sun, Liping / Peng, Fang / Zhang, Peng

    PloS one

    2024  Volume 19, Issue 1, Page(s) e0295626

    Abstract: Due to the inconsistent findings from various studies, the role of gene polymorphisms in the renin-angiotensin system in influencing the development of cardiomyopathy remains unclear. In this study, we conducted a systematic review and meta-analysis to ... ...

    Abstract Due to the inconsistent findings from various studies, the role of gene polymorphisms in the renin-angiotensin system in influencing the development of cardiomyopathy remains unclear. In this study, we conducted a systematic review and meta-analysis to summarize the findings regarding the impact of angiotensin converting enzyme (ACE) I/D, angiotensinogen (AGT) M235T, and angiotensin II Type 1 receptor (AGTR1) A1166C gene polymorphisms in patients with cardiomyopathy. We performed a comprehensive search of several electronic databases, including PubMed, Embase, the Cochrane Library, and Web of Science, covering articles published from the time of database creation to April 17, 2023. Studies on the assessment of genetic polymorphisms in genes related to the renin-angiotensin system in relation to cardiomyopathy were included. The primary outcome was cardiomyopathy. Risk of bias was assessed using the Newcastle-Ottawa Scale scale. The meta-analysis includes 19 studies with 4,052 cases and 5,592 controls. The ACE I/D polymorphisms were found to be associated with cardiomyopathy (allelic model D vs I: OR = 1.29, 95CI% = 1.08-1.52; dominant model DD+ID vs II: OR = 1.43, 95CI% = 1.01-2.02; recessive model DD vs ID+II: OR = 0.79, 95CI% = 0.64-0.98). AGT M235T polymorphism and cardiomyopathy were not significantly correlated (allelic model T vs M: OR = 1.26, 95CI% = 0.96-1.66; dominant model TT+MT vs MM: OR = 1.30, 95CI% = 0.98-1.73; recessive model TT vs MT+MM: OR = 0.63, 95CI% = 0.37-1.07). AGTR1 polymorphism and cardiomyopathy were not significantly associated under allelic model A vs C (OR = 0.69, 95CI% = 0.46-1.03) and recessive model AA vs CA+CC (OR = 0.89, 95CI% = 0.34-2.30), but under the dominant model AA+CA vs CC (OR = 0.51, 95CI% = 0.38-0.68). The current meta-analysis reveals that polymorphisms in ACE I/D may be a genetic risk factor for cardiomyopathy. There is an association between AGTR1 gene polymorphisms and risk of cardiomyopathy under the specific model.
    MeSH term(s) Humans ; Renin-Angiotensin System/genetics ; Risk Factors ; Polymorphism, Genetic ; Peptidyl-Dipeptidase A/genetics ; Angiotensinogen/genetics ; Cardiomyopathies/genetics ; Receptor, Angiotensin, Type 1/genetics
    Chemical Substances Peptidyl-Dipeptidase A (EC 3.4.15.1) ; Angiotensinogen (11002-13-4) ; Receptor, Angiotensin, Type 1
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0295626
    Database MEDical Literature Analysis and Retrieval System OnLINE

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