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  1. Article: Rapidly progressive and fatal distant spontaneous gas gangrene due to

    Sivasubramanian, Geetha

    IDCases

    2021  Volume 24, Page(s) e01129

    Abstract: ... ...

    Abstract Clostridium
    Language English
    Publishing date 2021-04-22
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2021.e01129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Generalized tetanus in a landscaper without obvious wounds.

    Sivasubramanian, Geetha

    IDCases

    2020  Volume 22, Page(s) e01005

    Abstract: Tetanus is rare and potentially fatal infection in the US. Its incidence has declined dramatically over the years in developed countries due to robust immunization programs. We describe a case of generalized tetanus in a 66-year-old inadequately ... ...

    Abstract Tetanus is rare and potentially fatal infection in the US. Its incidence has declined dramatically over the years in developed countries due to robust immunization programs. We describe a case of generalized tetanus in a 66-year-old inadequately vaccinated landscaper who presented with classical symptoms but did not have any open wounds leading to delay in initial diagnosis but was successfully managed once the diagnosis was established.
    Language English
    Publishing date 2020-11-02
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2020.e01005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Delayed clearance of monkeypox virus in a patient with co infection with secondary syphilis.

    Opardija, Almira / Sivasubramanian, Geetha

    IDCases

    2023  Volume 31, Page(s) e01707

    Abstract: Several studies from the current 2022 monkeypox (MPX) outbreak have documented co-infections with sexually transmitted infections (STIs), such as gonorrhea, chlamydia, and syphilis. We present a patient with MPX and secondary syphilis who failed to clear ...

    Abstract Several studies from the current 2022 monkeypox (MPX) outbreak have documented co-infections with sexually transmitted infections (STIs), such as gonorrhea, chlamydia, and syphilis. We present a patient with MPX and secondary syphilis who failed to clear the MPX virus 30 days after illness onset despite a 14-day course of tecovirimat therapy.
    Language English
    Publishing date 2023-02-01
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2023.e01707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Diagnostic delays in cutaneous coccidioidomycosis: A report from Central California.

    Policepatil, Seema M / Sivasubramanian, Geetha

    Medical mycology

    2023  Volume 61, Issue 11

    Abstract: Cutaneous Coccidioidomycosis (CC) infection can present with a wide variety of clinical presentations and is well known as a 'great imitator'. We performed a retrospective analysis of patients with CC in a large referral center in Central Valley, ... ...

    Abstract Cutaneous Coccidioidomycosis (CC) infection can present with a wide variety of clinical presentations and is well known as a 'great imitator'. We performed a retrospective analysis of patients with CC in a large referral center in Central Valley, California, from 2010 to 2022 using the ICD9 and ICD10 codes for coccidioidomycosis and CC. We identified 40 patients with CC during the study period. The mean age of the study population was 43 years (with standard deviation of 14.08). Among these, 60% were men and 40% women. The appearance of the lesions varied from ulcers, plaques, nodules, blisters, cellulitis, and abscesses. The most common site of CC lesions was in the lower extremities (42.5%), followed by upper extremities (30%), chest and abdomen, head and neck (25% each). Only 22.5% of the 40 cases were diagnosed as CC and 15% were diagnosed as erythema nodosum. Rest were diagnosed initially as bacterial cellulitis in 37.5%, tinea in 7.5%, and others in 12.5%. There was resolution of the cutaneous lesions in all patients with antifungal treatment. The mean time of diagnosis from onset of symptoms on an average was 12 weeks (8-16 weeks) in our study with 75% cases initially misdiagnosed. Comprehensive knowledge about the manifestations and evaluation of CC among primary care providers and emergency room physicians is essential to prevent delays in diagnosis and treatment.
    MeSH term(s) Male ; Humans ; Female ; Adult ; Coccidioidomycosis/diagnosis ; Coccidioidomycosis/drug therapy ; Coccidioidomycosis/epidemiology ; Coccidioidomycosis/veterinary ; Delayed Diagnosis/veterinary ; Cellulitis/veterinary ; Retrospective Studies ; California/epidemiology ; Coccidioides
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1421796-x
    ISSN 1460-2709 ; 1369-3786
    ISSN (online) 1460-2709
    ISSN 1369-3786
    DOI 10.1093/mmy/myad107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 520: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Cryptococcus neoformans

    Ghanem, Hebah / Sivasubramanian, Geetha

    Case reports in infectious diseases

    2021  Volume 2021, Page(s) 5597473

    Abstract: Cryptococcus ... ...

    Abstract Cryptococcus neoformans
    Language English
    Publishing date 2021-06-04
    Publishing country Egypt
    Document type Case Reports
    ZDB-ID 2627642-2
    ISSN 2090-6633 ; 2090-6625
    ISSN (online) 2090-6633
    ISSN 2090-6625
    DOI 10.1155/2021/5597473
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Strongyloides Hyperinfection Syndrome among COVID-19 Patients Treated with Corticosteroids.

    Kim, Jani M / Sivasubramanian, Geetha

    Emerging infectious diseases

    2022  Volume 28, Issue 7, Page(s) 1531–1533

    Abstract: Widespread use of corticosteroids for COVID-19 treatment has led to Strongyloides reactivation and severe disease in patients from endemic areas. We describe a US patient with COVID-19 and Strongyloides hyperinfection syndrome and review other reported ... ...

    Abstract Widespread use of corticosteroids for COVID-19 treatment has led to Strongyloides reactivation and severe disease in patients from endemic areas. We describe a US patient with COVID-19 and Strongyloides hyperinfection syndrome and review other reported cases. Our findings highlight the need for Strongyloides screening and treatment in high-risk populations.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Animals ; COVID-19/drug therapy ; Humans ; Strongyloides stercoralis ; Strongyloidiasis/diagnosis ; Strongyloidiasis/drug therapy ; Strongyloidiasis/epidemiology ; Syndrome
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2022-06-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2807.220198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Double Trouble: A Primary Epstein-Barr Virus Infection Causing Cholestatic Hepatitis and Hemophagocytic Lymphohistiocytosis.

    Lin, Joanne / Sivasubramanian, Geetha

    Cureus

    2022  Volume 14, Issue 11, Page(s) e31014

    Abstract: Primary infection with Epstein-Barr virus (EBV) is very common, often manifesting as mononucleosis syndrome with fatigue, sore throat, fever, and enlarged lymph nodes. Liver involvement occurs in many cases with mildly elevated liver enzymes. However, it ...

    Abstract Primary infection with Epstein-Barr virus (EBV) is very common, often manifesting as mononucleosis syndrome with fatigue, sore throat, fever, and enlarged lymph nodes. Liver involvement occurs in many cases with mildly elevated liver enzymes. However, it is rare to see EBV infection present as cholestatic hepatitis. Another rare complication of primary EBV infection is hemophagocytic lymphohistiocytosis (HLH). We describe a patient with primary EBV infection who presented with fatigue and jaundice, subsequent rash, and reactive lymphocytosis. The patient was noted to have cholestatic hepatitis and was highly suspected to have HLH based on laboratory values, including elevated ferritin, triglyceride, and interleukin-2 levels. He showed clinical improvement with HLH treatment using dexamethasone, etoposide, and rituximab. We further review the clinical manifestations, pathogenesis, and management of EBV-associated cholestatic hepatitis and EBV-HLH. Early diagnosis of primary EBV infection is emphasized in order to properly recognize and treat potentially life-threatening complications.
    Language English
    Publishing date 2022-11-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.31014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Coccidioidal meningitis and neurosyphilis co-infection in a non-HIV patient.

    Kim, Jani M / Sivasubramanian, Geetha

    Medical mycology case reports

    2021  Volume 34, Page(s) 5–7

    Abstract: ... ...

    Abstract Coccidioides
    Language English
    Publishing date 2021-08-09
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2670415-8
    ISSN 2211-7539
    ISSN 2211-7539
    DOI 10.1016/j.mmcr.2021.08.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Efficacy and safety of Isavuconazole for the treatment of invasive

    Sivasubramanian, Geetha / Chandrasekar, Pranatharthi H

    Expert opinion on pharmacotherapy

    2022  Volume 23, Issue 5, Page(s) 543–549

    Abstract: Introduction: Invasive aspergillosis is associated with high morbidity and mortality in immunocompromised patients. It is now increasingly reported in critically ill patients, including those with respiratory viral infections, such as influenza and ... ...

    Abstract Introduction: Invasive aspergillosis is associated with high morbidity and mortality in immunocompromised patients. It is now increasingly reported in critically ill patients, including those with respiratory viral infections, such as influenza and COVID-19. Antifungal management is challenging due to diagnostic delay, adverse drug reactions, drug-drug interactions, narrow therapeutic window, and the emergence of resistance. Isavuconazole is the most recent FDA approved azole for the treatment of invasive aspergillosis, with data continuing to accumulate.
    Areas covered: The authors review the safety and efficacy of isavuconazole in the management of invasive aspergillosis based on the currently available evidence. The authors also report on the structure, mechanism of action, pharmacokinetic properties, in vitro and in vivo studies as well as clinical safety and efficacy reports of isavuconazole since its FDA approval.
    Expert opinion: Isavuconazole is non-inferior to voriconazole and is a safe, effective, and better tolerated option for the treatment of invasive aspergillosis. It offers several advantages over other antifungal agents, including having a better adverse event profile with respect to hepatotoxicity, neuro-visual toxicity, QTc prolongation, as well as a stable pharmacokinetic profile obviating the need for therapeutic drug monitoring. Further studies are needed to evaluate its performance in prophylaxis against invasive aspergillosis as well as in the treatment of aspergillosis in critically ill patients without underlying cancer or transplant.
    MeSH term(s) Antifungal Agents/adverse effects ; Aspergillosis/chemically induced ; Aspergillosis/drug therapy ; COVID-19/drug therapy ; Delayed Diagnosis ; Humans ; Nitriles/adverse effects ; Pyridines ; Triazoles/adverse effects
    Chemical Substances Antifungal Agents ; Nitriles ; Pyridines ; Triazoles ; isavuconazole (60UTO373KE)
    Language English
    Publishing date 2022-01-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001535-5
    ISSN 1744-7666 ; 1465-6566
    ISSN (online) 1744-7666
    ISSN 1465-6566
    DOI 10.1080/14656566.2022.2032645
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5130: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Strongyloides Hyperinfection Syndrome among COVID-19 Patients Treated with Corticosteroids

    Jani M. Kim / Geetha Sivasubramanian

    Emerging Infectious Diseases, Vol 28, Iss 7, Pp 1531-

    2022  Volume 1533

    Abstract: Widespread use of corticosteroids for COVID-19 treatment has led to Strongyloides reactivation and severe disease in patients from endemic areas. We describe a US patient with COVID-19 and Strongyloides hyperinfection syndrome and review other reported ... ...

    Abstract Widespread use of corticosteroids for COVID-19 treatment has led to Strongyloides reactivation and severe disease in patients from endemic areas. We describe a US patient with COVID-19 and Strongyloides hyperinfection syndrome and review other reported cases. Our findings highlight the need for Strongyloides screening and treatment in high-risk populations.
    Keywords parasites ; Strongyloides stercoralis ; COVID-19 ; respiratory infections ; Strongyloides ; severe acute respiratory syndrome coronavirus 2 ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
    Language English
    Publishing date 2022-07-01T00:00:00Z
    Publisher Centers for Disease Control and Prevention
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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