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  1. Article ; Online: Death - My enemy

    Sourabh Aggarwal

    Annals of Indian Academy of Neurology, Vol 17, Iss 1, Pp 137-

    2014  Volume 137

    Keywords Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Death - My enemy

    Sourabh Aggarwal

    Annals of Indian Academy of Neurology, Vol 17, Iss 1, Pp 137-

    2014  Volume 137

    Keywords Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Death - My enemy

    Sourabh Aggarwal

    Annals of Indian Academy of Neurology, Vol 17, Iss 1, Pp 137-

    2014  Volume 137

    Keywords Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Ambroxol

    Prajwal Dhanve / Punita Aggarwal / Sourabh Choure / Devendra K. Dhaked / Sugato Banerjee

    Health Sciences Review, Vol 7, Iss , Pp 100096- (2023)

    A potential therapeutics against neurodegeneration

    2023  

    Abstract: Ambroxol hydrochloride is a pharmacological chaperone approved by FDA as an expectorant. Currently, it is used as an antitussive and anti-asthmatic agent. Besides mucolytic properties, ambroxol has antioxidant, anti-inflammatory, and anesthetic ... ...

    Abstract Ambroxol hydrochloride is a pharmacological chaperone approved by FDA as an expectorant. Currently, it is used as an antitussive and anti-asthmatic agent. Besides mucolytic properties, ambroxol has antioxidant, anti-inflammatory, and anesthetic properties. Its effects on the central nervous system (CNS) are currently being explored. Ambroxol has been reported to inhibit microglial activation and decreases proinflammatory cytokines in the brain. It crosses the blood-brain barrier and may be neuroprotective in Parkinson's, Amyotrophic lateral sclerosis, Gaucher disease, neuroinflammation, and spinal cord injury. Here we review the CNS effects of ambroxol and its therapeutic potential against neurodegenerative disorders.
    Keywords Parkinson's disease ; Amyotrophic lateral sclerosis ; Glucocerebrosidase ; Alzheimer's disease ; Gaucher disease ; Neuroinflammation ; Medicine ; R
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Meta-analysis of Cerebrospinal Fluid Cell Count and Biochemistry to Diagnose Meningitis in Infants Aged < 90 Days.

    Anne, Rajendra P / Dutta, Sourabh / Balasubramanian, Haribalakrishna / Aggarwal, Ashutosh N / Chadha, Neelima / Kumar, Praveen

    American journal of perinatology

    2023  

    Abstract: Objective:  Cerebrospinal fluid (CSF) white blood cell (WBC) count, protein, and glucose (cytochemistry) are performed to aid in the diagnosis of meningitis in young infants. However, studies have reported varying diagnostic accuracies. We assessed the ... ...

    Abstract Objective:  Cerebrospinal fluid (CSF) white blood cell (WBC) count, protein, and glucose (cytochemistry) are performed to aid in the diagnosis of meningitis in young infants. However, studies have reported varying diagnostic accuracies. We assessed the diagnostic accuracy of CSF cytochemistry in infants below 90 days and determined the certainty of evidence.
    Study design:  We searched PubMed, Embase, Cochrane Library, Ovid, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Scopus databases in August 2021. We included studies that evaluated the diagnostic accuracy of CSF cytochemistry compared with CSF culture, Gram stain, or polymerase chain reaction in neonates and young infants <90 days with suspected meningitis. We pooled data using the hierarchical summary receiver operator characteristic (ROC) model.
    Results:  Of the 10,720 unique records, 16 studies were eligible for meta-analysis, with a cumulative sample size of 31,695 (15 studies) for WBC, 12,936 (11 studies) for protein, and 1,120 (4 studies) for glucose. The median (Q
    Conclusion:  CSF WBC and protein have good diagnostic accuracy for the diagnosis of meningitis in infants below 90 days of age. CSF glucose has good specificity but poor sensitivity. However, we could not identify enough studies to define an optimal threshold for the positivity of these tests.
    Key points: · Median specificity of CSF leucocyte count, protein and glucose are similar in young infants.. · At median specificity, CSF leukocyte count and protein are more sensitive than glucose.. · Owing to inadequate data, bivariate modelling to suggest optimal diagnostic thresholds is not possible..
    Language English
    Publishing date 2023-06-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/a-2095-6729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Dyslexic savants.

    Aggarwal, Sourabh

    Annals of Indian Academy of Neurology

    2010  Volume 13, Issue 1, Page(s) 74

    Language English
    Publishing date 2010-04-16
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/0972-2327.61288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Instantaneous Wave-free Ratio versus Fractional Flow Reserve.

    Aggarwal, Sourabh / Pavlides, Gregory

    The New England journal of medicine

    2017  Volume 377, Issue 16, Page(s) 1595

    MeSH term(s) Coronary Stenosis ; Fractional Flow Reserve, Myocardial ; Humans
    Language English
    Publishing date 2017--19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc1711333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Tobacco smoking by medical students: KAP study.

    Aggarwal, Sourabh

    Annals of thoracic medicine

    2010  Volume 5, Issue 4, Page(s) 249–50; author reply 250

    Language English
    Publishing date 2010-10-26
    Publishing country India
    Document type Comment ; Letter
    ZDB-ID 2241287-6
    ISSN 1998-3557 ; 1817-1737
    ISSN (online) 1998-3557
    ISSN 1817-1737
    DOI 10.4103/1817-1737.69121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: My first emergency duty!

    Aggarwal, Sourabh

    Annals of Indian Academy of Neurology

    2010  Volume 14, Issue 2, Page(s) 135

    Language English
    Publishing date 2010-12-29
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The peer reviewers.

    Aggarwal, Sourabh

    Indian journal of urology : IJU : journal of the Urological Society of India

    2010  Volume 26, Issue 2, Page(s) 317

    Language English
    Publishing date 2010-09-24
    Publishing country India
    Document type Journal Article
    ZDB-ID 639268-4
    ISSN 1998-3824 ; 0970-1591
    ISSN (online) 1998-3824
    ISSN 0970-1591
    DOI 10.4103/0970-1591.65418
    Database MEDical Literature Analysis and Retrieval System OnLINE

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