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  1. Article ; Online: Abdominal pelvic CT findings compared between COVID-19 positive and COVID-19 negative patients in the emergency department setting.

    Funt, Stacey A / Cohen, Stuart L / Wang, Jason J / Sanelli, Pina C / Barish, Matthew A

    Abdominal radiology (New York)

    2020  Volume 46, Issue 4, Page(s) 1498–1505

    Abstract: Purpose: Manifestations of COVID-19 are primarily respiratory based, however, gastrointestinal symptoms are now recognized as an important component of the disease. The purpose of this study is to evaluate differences in abdominal pelvic CT findings in ... ...

    Abstract Purpose: Manifestations of COVID-19 are primarily respiratory based, however, gastrointestinal symptoms are now recognized as an important component of the disease. The purpose of this study is to evaluate differences in abdominal pelvic CT findings in the emergency department by COVID-19 test result.
    Methods: This retrospective study identified patients tested by PCR for COVID-19 infection who underwent abdominal pelvic CT scan in the ED across an academic health system from March 15 to April 15, 2020. Radiology reports were reviewed for the presence of ground glass opacity in the lungs and acute abdominal pathology. A subset of patients with acute abdominal pathology were identified with inflammatory pathology in organs with high ACE2 receptor expression including bowel, pancreas, urinary bladder, and kidney. CT findings for COVID positive versus negative patients were compared with Chi-square test.
    Results: 597 patients tested by PCR for COVID-19 infection underwent abdominal pelvic CT scan, 44% were COVID-19 positive. COVID-19 positive patients demonstrated significantly more ground glass opacity at the lung bases, 65.1%, (222/341) versus 12.4% (33/266), p < 0.001), and significantly less acute abdominal findings, 23.8% (81/341) versus 45.5% (121/266), p ≤ 0.001). When abdominal pathology was present, COVID-19 positive patients had higher rate of inflammatory pathology 58% (47/81) versus 29.8% (36/121).
    Conclusions: In patients undergoing abdominopelvic CT from the ED, COVID-19 positive patients are more likely to have ground glass opacities at the lung bases and less likely to have acute abdominal pathology compared with COVID-19 negative patients. Further, COVID-19 positive patients are more likely to have inflammation of organs with high expression of ACE2 receptors than other types of acute abdominal pathology.
    MeSH term(s) COVID-19 ; Emergency Service, Hospital ; Humans ; Retrospective Studies ; SARS-CoV-2 ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-10-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2839786-1
    ISSN 2366-0058 ; 2366-004X
    ISSN (online) 2366-0058
    ISSN 2366-004X
    DOI 10.1007/s00261-020-02796-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1262: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Abdominal pelvic CT findings compared between COVID-19 positive and COVID-19 negative patients in the emergency department setting

    Funt, Stacey A / Cohen, Stuart L / Wang, Jason J / Sanelli, Pina C / Barish, Matthew A

    Abdom. radiology (Internet)

    Abstract: PURPOSE: Manifestations of COVID-19 are primarily respiratory based, however, gastrointestinal symptoms are now recognized as an important component of the disease. The purpose of this study is to evaluate differences in abdominal pelvic CT findings in ... ...

    Abstract PURPOSE: Manifestations of COVID-19 are primarily respiratory based, however, gastrointestinal symptoms are now recognized as an important component of the disease. The purpose of this study is to evaluate differences in abdominal pelvic CT findings in the emergency department by COVID-19 test result. METHODS: This retrospective study identified patients tested by PCR for COVID-19 infection who underwent abdominal pelvic CT scan in the ED across an academic health system from March 15 to April 15, 2020. Radiology reports were reviewed for the presence of ground glass opacity in the lungs and acute abdominal pathology. A subset of patients with acute abdominal pathology were identified with inflammatory pathology in organs with high ACE2 receptor expression including bowel, pancreas, urinary bladder, and kidney. CT findings for COVID positive versus negative patients were compared with Chi-square test. RESULTS: 597 patients tested by PCR for COVID-19 infection underwent abdominal pelvic CT scan, 44% were COVID-19 positive. COVID-19 positive patients demonstrated significantly more ground glass opacity at the lung bases, 65.1%, (222/341) versus 12.4% (33/266), p < 0.001), and significantly less acute abdominal findings, 23.8% (81/341) versus 45.5% (121/266), p ≤ 0.001). When abdominal pathology was present, COVID-19 positive patients had higher rate of inflammatory pathology 58% (47/81) versus 29.8% (36/121). CONCLUSIONS: In patients undergoing abdominopelvic CT from the ED, COVID-19 positive patients are more likely to have ground glass opacities at the lung bases and less likely to have acute abdominal pathology compared with COVID-19 negative patients. Further, COVID-19 positive patients are more likely to have inflammation of organs with high expression of ACE2 receptors than other types of acute abdominal pathology.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #843955
    Database COVID19

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  3. Article: Ovarian malignancies.

    Funt, Stacey A / Hricak, Hedvig

    Topics in magnetic resonance imaging : TMRI

    2003  Volume 14, Issue 4, Page(s) 329–337

    Abstract: Ovarian cancer is the second most common pelvic tumor and the leading cause of death from a gynecologic malignancy. MRI plays a strategic role in patient care for initial evaluation and treatment planning in patients with ovarian cancer. This article ... ...

    Abstract Ovarian cancer is the second most common pelvic tumor and the leading cause of death from a gynecologic malignancy. MRI plays a strategic role in patient care for initial evaluation and treatment planning in patients with ovarian cancer. This article reviews the pathologic classification and characteristic findings on MRI of ovarian malignancies, patterns of tumor spread and staging, and the utility of cross-sectional imaging prior to primary and secondary to cytoreproductive surgery.
    MeSH term(s) Female ; Humans ; Magnetic Resonance Imaging/methods ; Neoplasm Recurrence, Local/diagnosis ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging ; Neoplasm, Residual ; Ovarian Neoplasms/classification ; Ovarian Neoplasms/diagnosis ; Ovarian Neoplasms/pathology ; Ovarian Neoplasms/surgery ; Reoperation
    Language English
    Publishing date 2003-10-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1112716-8
    ISSN 0899-3459
    ISSN 0899-3459
    DOI 10.1097/00002142-200308000-00005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3430: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Detection and characterization of adnexal masses.

    Funt, Stacey A / Hann, Lucy E

    Radiologic clinics of North America

    2002  Volume 40, Issue 3, Page(s) 591–608

    Abstract: The main challenge to the radiologist is to differentiate benign from malignant adnexal masses. Both US and MRI perform well for prediction of benignity. There is less specificity for diagnosis of malignancy but features, such as papillary projections, ... ...

    Abstract The main challenge to the radiologist is to differentiate benign from malignant adnexal masses. Both US and MRI perform well for prediction of benignity. There is less specificity for diagnosis of malignancy but features, such as papillary projections, thickened septations, and internal vascularity within nodules, aid in this differentiation. The combination of morphology and Doppler characteristics provide the most accurate US diagnosis. For sonographically indeterminate masses, MRI is useful for additional lesion characterization. Analysis of T1- and T2-weighted signal intensities for benign-appearing lesions with the addition of fat saturation for high signal on T1-weighted sequences may lead to an exact diagnosis or a narrow differential. For cases considered suspicious by TVUS, more specific diagnosis by MRI may obviate the need for surgery or otherwise change management by identification of benign etiology.
    MeSH term(s) Adnexal Diseases/diagnosis ; Adnexal Diseases/diagnostic imaging ; Adnexal Diseases/pathology ; Diagnosis, Differential ; Female ; Genital Neoplasms, Female/diagnosis ; Genital Neoplasms, Female/diagnostic imaging ; Genital Neoplasms, Female/pathology ; Humans ; Magnetic Resonance Imaging ; Ultrasonography, Doppler
    Language English
    Publishing date 2002-07-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 215712-3
    ISSN 1557-8275 ; 0033-8389
    ISSN (online) 1557-8275
    ISSN 0033-8389
    DOI 10.1016/s0033-8389(01)00009-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Subcutaneous nodules at the injection site of low-molecular-weight heparin: a mimic of metastatic disease at CT.

    Funt, Stacey A / Hidalgo, Alberto / Panicek, David M

    Journal of computer assisted tomography

    2002  Volume 26, Issue 4, Page(s) 520–523

    Abstract: Purpose: To describe the appearance and prevalence of subcutaneous nodules in the anterior abdominal wall seen at CT in cancer patients receiving subcutaneous injections of low-molecular-weight heparin (LMWH).: Methods: CT examinations were reviewed ... ...

    Abstract Purpose: To describe the appearance and prevalence of subcutaneous nodules in the anterior abdominal wall seen at CT in cancer patients receiving subcutaneous injections of low-molecular-weight heparin (LMWH).
    Methods: CT examinations were reviewed in 426 patients receiving subcutaneous abdominal wall injections of LMWH for the presence of nodules. Nodules were evaluated for contour, maximal diameter, CT attenuation, and presence of hazy changes or air in the surrounding fat.
    Results: Fourteen (3%) of the 426 patients had nodules attributable to subcutaneous injections of LMWH. Findings included poorly defined borders (100%), adjacent hazy soft tissue changes (100%), adjacent air (57%), and a mean CT attenuation of -4.4 HU (range: -50-40 HU). Three (0.7%) of 426 patients had nodules caused by metastatic disease. One (33%) nodule had poorly defined borders, two (67%) had surrounding hazy changes, one (33%) had air in adjacent tissue, and there was a mean CT attenuation of 44 HU (range: 14-140 HU). One (0.2%) patient had a subcutaneous nodule of uncertain etiology.
    Conclusion: Patients receiving subcutaneous injections of LMWH may develop nodules at the injection sites. Such nodules can resemble metastatic tumor deposits at CT, and careful correlation with clinical history and growth trends of metastatic deposits elsewhere in the patient is needed to avoid misdiagnosis.
    MeSH term(s) Abdominal Muscles/diagnostic imaging ; Abdominal Muscles/drug effects ; Adult ; Aged ; Aged, 80 and over ; Diagnosis, Differential ; Drug Eruptions/diagnostic imaging ; Female ; Heparin, Low-Molecular-Weight/administration & dosage ; Heparin, Low-Molecular-Weight/adverse effects ; Humans ; Hypersensitivity, Delayed/chemically induced ; Hypersensitivity, Delayed/diagnostic imaging ; Injections, Subcutaneous/adverse effects ; Male ; Middle Aged ; Retrospective Studies ; Soft Tissue Neoplasms/diagnostic imaging ; Soft Tissue Neoplasms/secondary ; Tomography, X-Ray Computed
    Chemical Substances Heparin, Low-Molecular-Weight
    Language English
    Publishing date 2002-07
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 80392-3
    ISSN 1532-3145 ; 0363-8715
    ISSN (online) 1532-3145
    ISSN 0363-8715
    DOI 10.1097/00004728-200207000-00007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1388: Show issues Location:
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  6. Article: Role of CT in the management of recurrent ovarian cancer.

    Funt, Stacey A / Hricak, Hedvig / Abu-Rustum, Nadeem / Mazumdar, Madhu / Felderman, Howard / Chi, Dennis S

    AJR. American journal of roentgenology

    2004  Volume 182, Issue 2, Page(s) 393–398

    Abstract: Objective: The purpose of this study was to evaluate the potential role of preoperative CT in patients with recurrent ovarian cancer who undergo secondary cytoreductive surgery.: Materials and methods: Preoperative CT examinations of 36 consecutive ... ...

    Abstract Objective: The purpose of this study was to evaluate the potential role of preoperative CT in patients with recurrent ovarian cancer who undergo secondary cytoreductive surgery.
    Materials and methods: Preoperative CT examinations of 36 consecutive patients (age range, 30-75 years; mean age, 55 years) were reviewed retrospectively. Patients had recurrent ovarian cancer and secondary cytoreduction within a mean CT-surgery interval of 22 days (range, 2-69 days). The CT findings recorded were upper abdominal metastases (e.g., peritoneal carcinomatosis; perihepatic, perisplenic, gastrohepatic or gastrosplenic ligaments; gallbladder fossa; falciform ligament; lesser sac), lymphadenopathy (above or below the renal hilum), liver metastasis, large- and small-bowel obstruction, hydronephrosis, ascites, and the presence of a pelvic mass. CT findings and cancer antigen-125 (CA-125) levels were correlated with surgical resectability.
    Results: At surgery, tumors in 27 patients were optimally debulked (residual disease of <or= 1 cm) and in nine patients were nonresectable. Using multivariate analysis, hydronephrosis (odds ratio = 19.4, p = 0.03) and invasion of pelvic sidewall (odds ratio = 35.6, p = 0.006) were found to be most indicative of tumor nonresectability. The presence of small-bowel obstruction; nodal or perihepatic liver metastasis; ascites; peritoneal carcinomatosis; bladder, rectum, sigmoid colon, or vaginal involvement; or infrarenal paraaortic adenopathy; and the level of CA-125 were not strong indicators of tumor nonresectability.<br />Conclusion: In patients with recurrent ovarian carcinoma considered for secondary cytoreductive surgery, preoperative CT can be helpful in identifying the extent of the disease and can be used as an adjunct to treatment planning and management decisions.
    MeSH term(s) Adult ; Aged ; Female ; Gynecologic Surgical Procedures ; Humans ; Middle Aged ; Neoplasm Recurrence, Local/diagnostic imaging ; Neoplasm Recurrence, Local/surgery ; Ovarian Neoplasms/diagnostic imaging ; Ovarian Neoplasms/surgery ; Ovary/diagnostic imaging ; Ovary/surgery ; Reoperation ; Retrospective Studies ; Tomography, X-Ray Computed ; Treatment Outcome
    Language English
    Publishing date 2004-02
    Publishing country United States
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/ajr.182.2.1820393
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    Ue I Zs.57: Show issues Location:
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  7. Article: Utility of sonography for small hepatic lesions found on computed tomography in patients with cancer.

    Eberhardt, Steven C / Choi, Patricia H / Bach, Ariadne M / Funt, Stacey A / Felderman, Howard E / Hann, Lucy E

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2003  Volume 22, Issue 4, Page(s) 335–43; quiz 345–6

    Abstract: Objective: To assess the performance of sonography in evaluating small indeterminate liver lesions detected on computed tomography in patients with cancer.: Methods: Radiology database review from January 1, 1998, to August 4, 2000, identified 76 ... ...

    Abstract Objective: To assess the performance of sonography in evaluating small indeterminate liver lesions detected on computed tomography in patients with cancer.
    Methods: Radiology database review from January 1, 1998, to August 4, 2000, identified 76 patients with 124 indeterminate hepatic lesions smaller than 1.5 cm on computed tomography who had abdominal sonography within 3 months. Sonographic reports and images were reviewed to assess whether lesions were referenced or specifically sought and to verify lesion correspondence, detection, and characterization. The validity of sonographic characterization was determined by histopathologic examination or follow-up imaging (mean time to follow up, 17 months; range, 6.5-38.8 months).
    Results: Sixty (48%) of 124 indeterminate lesions were evident on sonography. Detection improved when lesions were specifically sought and lesion size was greater than 0.5 cm. Forty (66%) of 61 lesions were detected when the radiologist referenced the preceding computed tomography versus 20 (32%) of 63 lesions when the computed tomographic findings were not referenced (P = .0004). Fifty-one (67%) of 76 lesions measuring 0.6 to 1.5 cm were detected on sonography versus 9 (19%) of 48 lesions measuring 0.1 to 0.5 cm. Lesion size (P < .0001) and body habitus (P = .02) were significant factors influencing lesion detection. Sonography characterized 56 (93%) of 60 detected lesions (33 cysts, 18 solid lesions/metastases, and 5 hemangiomas). Sonographic diagnoses were supported in 42 (93%) of 45 lesions by follow-up imaging (37 of 40) or histopathologic examination (5 of 5).
    Conclusions: Sonography may be useful in cancer patients with average body habitus to characterize small (0.6- to 1.5-cm) indeterminate liver lesions detected on computed tomography.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Breast Neoplasms/pathology ; Colorectal Neoplasms/pathology ; Female ; Humans ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/secondary ; Male ; Middle Aged ; Retrospective Studies ; Tomography, X-Ray Computed ; Ultrasonography
    Language English
    Publishing date 2003-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.7863/jum.2003.22.4.335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 495: Show issues

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