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  1. Article ; Online: The First Oxovanadium(V)-Thiolate Complex, [VO(SCH(2)CH(2))(3)N].

    Nanda, Kausik K. / Sinn, Ekkehard / Addison, Anthony W.

    Inorganic chemistry

    1996  Volume 35, Issue 1, Page(s) 1–2

    Language English
    Publishing date 1996-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/ic9512486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Atomistic, macromolecular model of the

    Addison, Bennett / Bu, Lintao / Bharadwaj, Vivek / Crowley, Meagan F / Harman-Ware, Anne E / Crowley, Michael F / Bomble, Yannick J / Ciesielski, Peter N

    Science advances

    2024  Volume 10, Issue 1, Page(s) eadi7965

    Abstract: Plant secondary cell walls (SCWs) are composed of a heterogeneous interplay of three major biopolymers: cellulose, hemicelluloses, and lignin. Details regarding specific intermolecular interactions and higher-order architecture of the SCW superstructure ... ...

    Abstract Plant secondary cell walls (SCWs) are composed of a heterogeneous interplay of three major biopolymers: cellulose, hemicelluloses, and lignin. Details regarding specific intermolecular interactions and higher-order architecture of the SCW superstructure remain ambiguous. Here, we use solid-state nuclear magnetic resonance (ssNMR) measurements to infer refined details about the structural configuration, intermolecular interactions, and relative proximity of all three major biopolymers within air-dried
    MeSH term(s) Populus ; Cellulose ; Magnetic Resonance Spectroscopy ; Biopolymers ; Plants ; Cell Wall
    Chemical Substances Cellulose (9004-34-6) ; Biopolymers
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.adi7965
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Integrating a Resilience Framework to Assess Implementation of a Novel HIV Care Re-Engagement Model in NYC.

    Baim-Lance, Abigail / Addison, Diane / Archer, Norman / Gordon, Peter / Duke, Sharen / Shubert, Virginia / Nash, Denis / Robertson, McKaylee

    Journal of acquired immune deficiency syndromes (1999)

    2023  Volume 94, Issue 4, Page(s) 308–316

    Abstract: ... incorporating resilience.: Methods: We conducted semistructured interviews with implementation staff (N = 6 ... and meeting minutes and protocols document reviews (N = 35). The Consolidated Framework ...

    Abstract Background: The Bottom Up Project, a collaboration of clinical, community, and academic partners, consists of 7 major steps that leverage a health information exchange, a system for sharing patient health information, with real-time alerts to mobilize peer outreach workers to find and re-engage persons with HIV disconnected from care. Bottom Up faced implementation challenges in its start-up phase and produced effective responses leading to Project maturation, which we explore using a novel implementation science framework incorporating resilience.
    Methods: We conducted semistructured interviews with implementation staff (N = 6) and meeting minutes and protocols document reviews (N = 35). The Consolidated Framework for Implementation Research and a novel resilience framework guided thematic and process analyses. The resilience framework consisted of the following 3 resilience types: absorptive to cope with adversity, adaptive to adjust as short-term solutions, and transformative to structurally change.
    Results: The Project experienced 20 major challenges, 2-5 challenges per step. Challenges were multilevel and of chronic and crisis intensities. Implementers overcame challenges by leveraging multilevel factors that were absorptive, adaptive (most common), and transformative.
    Discussion: Bottom Up matured by practicing consistency and flexibility. The Project maintained core operations while under crisis-level stress by strategically simplifying or "downshifting" activities. Transformational responses suggest that specific initiatives can catalyze organizational change.
    Conclusions: Bottom Up implementation demonstrates using diverse tactics to respond to challenges, thereby shaping Project development and in turn organizations. Applying resilience to Consolidated Framework for Implementation Research helps build awareness of active and dynamic processes promoting or impeding the growth and success of intervention-oriented Projects.
    MeSH term(s) Humans ; HIV Infections/drug therapy ; HIV Infections/prevention & control ; New York City ; Delivery of Health Care/organization & administration
    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 645053-2
    ISSN 1944-7884 ; 1077-9450 ; 0897-5965 ; 0894-9255 ; 1525-4135
    ISSN (online) 1944-7884 ; 1077-9450
    ISSN 0897-5965 ; 0894-9255 ; 1525-4135
    DOI 10.1097/QAI.0000000000003285
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: FAM83A is a potential biomarker for breast cancer initiation.

    Marino, Natascia / German, Rana / Podicheti, Ram / Rockey, Pam / Sandusky, George E / Temm, Constance J / Nakshatri, Harikrishna / Addison, Rebekah J / Selman, Bryce / Althouse, Sandra K / Storniolo, Anna Maria V

    Biomarker research

    2022  Volume 10, Issue 1, Page(s) 8

    Abstract: ... in both a normal breast tissue microarray (TMA, N = 411) and a breast tumor TMA (N = 349). EGFR staining and ...

    Abstract Background: Family with sequence similarity 83 member A (FAM83A) presents oncogenic properties in several cancers including breast cancer. Recently, we reported FAM83A overexpression in normal breast tissues from women at high risk of breast cancer. We now hypothesize that FAM83A is a key factor in breast cancer initiation.
    Methods: Immunohistochemical staining was used to evaluate FAM83A protein levels in both a normal breast tissue microarray (TMA, N = 411) and a breast tumor TMA (N = 349). EGFR staining and its correlation with FAM83A expression were also assessed. Lentivirus-mediated manipulation of FAM83A expression in primary and hTERT-immortalized breast epithelial cells was employed. Biological and molecular alterations upon FAM83A overexpression/downregulation and FAM83A's interaction partners were investigated.
    Results: TMA analysis revealed a 1.5-fold increase in FAM83A expression level in breast cancer cases as compared with normal breast tissues (p < 0.0001). FAM83A protein expression was directly correlated with EGFR level in both normal and breast cancer tissues. In in vitro assays, exogenous expression of FAM83A in either primary or immortalized breast epithelial cells promoted cell viability and proliferation. Additionally, Ingenuity Pathway Analysis (IPA) revealed that FAM83A overexpression in primary cells affected the expression of genes involved in cellular morphology and metabolism. Mass spectrometry analysis identified DDX3X and LAMB3 as potential FAM83A interaction partners in primary cells, while we detected FAM83A interaction with cytoskeleton reorganization factors, including LIMA1, MYH10, PLEC, MYL6 in the immortalized cells.
    Conclusions: This study shows that FAM83A promotes metabolic activation in primary breast epithelial cells and cell proliferation in both primary and immortalized cells. These findings support its role in early breast oncogenesis.
    Language English
    Publishing date 2022-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2699926-2
    ISSN 2050-7771
    ISSN 2050-7771
    DOI 10.1186/s40364-022-00353-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Body-weight goals, trends, and weight-loss techniques among patients with peripheral arterial disease

    Addison, O / Yang, R / Serra, MC

    Nutrition and health. 2019 Mar., v. 25, no. 1

    2019  

    Abstract: ... who were overweight and obese (n = 240), to matched individuals without PAD (n = 480). Self-reported ...

    Abstract Obesity contributes to negative outcomes in peripheral arterial disease (PAD). Little is known about the body-weight goals and trends among patients with PAD. The aim of this study was to explore self-reported body-weight trends and methods used to achieve weight loss in patients with PAD. Data from the 1999–2004 National Health and Nutrition Examination Survey (NHANES) was utilized to compare individuals with PAD who were overweight and obese (n = 240), to matched individuals without PAD (n = 480). Self-reported body weight at age 25 years, 10 years prior and 1 year prior to the current assessment, and age and weight of heaviest body weight were compared. Self-reported weight-loss techniques during the past year were compared between groups. Individuals with PAD and controls reported similar weights 10 years prior (79.2 kg vs 78.5 kg; p = 0.60) and weight gain over the last 10 years of 5.7 kg. There was no significant difference in reported body weight at age 25 years, 10 years prior, 1 year prior, or heaviest weight. Compared with the control group, fewer participants with PAD reported attempted weight loss in the last year (27.50% vs 36.04%; p = 0.02) and were half as likely to report utilizing exercise as a weight-loss method (12.5% vs 21.7%; p = 0.003). These data indicate that those with PAD are less inclined to attempt weight loss, especially through means of increased physical activity. Future research is needed regarding the effectiveness of intentional weight-loss programs in this population.
    Keywords National Health and Nutrition Examination Survey ; exercise ; obesity ; patients ; weight gain ; weight loss
    Language English
    Dates of publication 2019-03
    Size p. 47-52.
    Publishing place SAGE Publications
    Document type Article
    ZDB-ID 603215-1
    ISSN 2047-945X ; 0260-1060
    ISSN (online) 2047-945X
    ISSN 0260-1060
    DOI 10.1177/0260106018817190
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: Alignment between values of dryland pastoralists and conservation needs for small mammals

    Addison, Jane / Chris R. Pavey

    Conservation biology. 2017 Apr., v. 31, no. 2

    2017  

    Abstract: ... Australia. Using semistructured surveys and open‐ended interviews (n = 43), we explored values ... to small mammals; over 80% (n = 36) agreed to strongly agreed that small mammals on their property were ... dog control (r² = 0.187, p = 0.142, n = 43). However, assigning great conservation value to small ...

    Abstract Policies for conservation outside protected areas, such as those designed to address the decline in Australian mammals, will not result in net improvements unless they address barriers to proenvironmental behavior. We used a mixed‐methods approach to explore potential value‐action gaps (disconnects between values and subsequent action) for small mammal conservation behaviors among pastoralists in dryland Australia. Using semistructured surveys and open‐ended interviews (n = 43), we explored values toward small mammals; uptake of a range of current and intended actions that may provide benefit to small mammals; and potential perceived barriers to their uptake. Pastoralists assigned great conservation value to small mammals; over 80% (n = 36) agreed to strongly agreed that small mammals on their property were important. These values did not translate into stated willingness to engage in voluntary cessation of wild‐dog control (r² = 0.187, p = 0.142, n = 43). However, assigning great conservation value to small mammals was strongly related to stated voluntary willingness to engage in the proenvironmental behavior most likely to result in benefits to small mammals: cat and fox control (r² = 0.558, p = 0.000, n = 43). There was no significant difference between stated voluntarily and incentivized willingness to engage in cat and fox control (p = 0.862, n = 43). The high levels of willingness to engage in voluntary cat and fox control highlight a potential entry point for addressing Australia's mammal declines because the engagement of pastoralists in conservation programs targeting cat and fox control is unlikely to be prevented by attitudinal constraints. Qualitative data suggest there is likely a subpopulation of pastoralists who value small mammals but do not wish to engage in formal conservation programs due to relational barriers with potential implementers. A long‐term commitment to engagement with pastoralists by implementers will thus be necessary for conservation success. On‐property cat and fox control programs that build and leverage trust, shared goals, collaboration, and shared learning experiences between stakeholders and that explicitly recognize the complexity of small mammal dynamics and the property‐level ecological knowledge of pastoralists are more likely to gain traction.
    Keywords arid lands ; conservation areas ; conservation programs ; foxes ; interviews ; issues and policy ; learning ; pastoralism ; small mammals ; stakeholders ; surveys ; Australia
    Language English
    Dates of publication 2017-04
    Size p. 331-342.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 58735-7
    ISSN 1523-1739 ; 0888-8892
    ISSN (online) 1523-1739
    ISSN 0888-8892
    DOI 10.1111/cobi.12803
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Evaluation of a CD206-Targeted Peptide for PET Imaging of Macrophages in Syngeneic Mouse Models of Cancer.

    Parker, Candace C / Bin Salam, Ahmad / Song, Patrick N / Gallegos, Carlos / Hunt, Addison / Yates, Clayton / Jaynes, Jesse / Lopez, Henry / Massicano, Adriana V F / Sorace, Anna G / Fernandez, Solana / Houson, Hailey A / Lapi, Suzanne E

    Molecular pharmaceutics

    2023  Volume 20, Issue 5, Page(s) 2415–2425

    Abstract: Tumor-associated macrophages (TAMs) are large phagocytic cells that play numerous roles in cancer biology and are an important component of the relationship between immune system response and tumor progression. The peptide, RP832c, targets the Mannose ... ...

    Abstract Tumor-associated macrophages (TAMs) are large phagocytic cells that play numerous roles in cancer biology and are an important component of the relationship between immune system response and tumor progression. The peptide, RP832c, targets the Mannose Receptor (CD206) expressed on M2-like macrophages and is cross-reactive to both human and murine CD206. Additionally, it exhibits therapeutic properties through its ability to shift the population of TAMs from an M2-like (protumor) toward an M1-like phenotype (antitumor) and has demonstrated promise in inhibiting tumor resistance in PD-L1 unresponsive melanoma murine models. In addition, it has shown inhibition in bleomycin-induced pulmonary fibrosis through interactions with CD206 macrophages.
    MeSH term(s) Animals ; Humans ; Mice ; Cell Line, Tumor ; Gallium Radioisotopes/chemistry ; Macrophages/metabolism ; Neoplasms/metabolism ; Peptides/metabolism ; Positron-Emission Tomography/methods ; Tissue Distribution ; Mannose Receptor/metabolism
    Chemical Substances Gallium Radioisotopes ; Peptides ; Mannose Receptor
    Language English
    Publishing date 2023-04-04
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2138405-8
    ISSN 1543-8392 ; 1543-8384
    ISSN (online) 1543-8392
    ISSN 1543-8384
    DOI 10.1021/acs.molpharmaceut.2c00977
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The Area-Wide Spatio-Temporal Distribution of Ceratitis capitata (Wiedemann) (Diptera: Tephritidae) in a Heterogenous Fruit Production Region of the Western Cape, South Africa

    Bekker, G.F.H.v.G / Addison, M.F / Addison, P / Baard, N / Niekerk, A. van

    African entomology. 2019 Apr. 25, v. 27, no. 1

    2019  

    Abstract: The area-wide spatio-temporal distribution of Ceratitis capitata (Wiedemann) (Diptera: Tephritidae) trap catches was investigated in the regions of Elgin/Grabouw, Villiersdorp and Vyeboom, collectively known as EGVV, Western Cape, South Africa. The ... ...

    Abstract The area-wide spatio-temporal distribution of Ceratitis capitata (Wiedemann) (Diptera: Tephritidae) trap catches was investigated in the regions of Elgin/Grabouw, Villiersdorp and Vyeboom, collectively known as EGVV, Western Cape, South Africa. The primary fruit crops planted in EGVV include various varieties and cultivars of pome fruit, stone fruit, citrus, wine grapes and berries. Fruit fly trapping data from four consecutive seasons were sourced from a centralised database managed by a non-profit company, which operates an area-wide integrated pest management (AW-IPM) programme, incorporating the sterile insect technique (SIT) for C. capitata fruits flies, within EGVV. Mean trap catch between regions and seasons was compared. The spatio-temporal variation of mean trap catch was also investigated. A geographic information system (GIS) was used to symbolise and map mean trap catch per trap location. There was no significant difference in the mean trap catch between regions. Significant differences did occur between some seasons in Villiersdorp and Vyeboom but not in Elgin/Grabouw. The spatial distribution of trap catches between seasons varied greatly, indicating no definitive pattern. However, traps with the highest seasonal trap catch occurred mostly in the southeastern parts of each region and traps with lower levels were distributed mostly in the northwestern parts of each region. The results suggest a relationship between the geographic characteristics of EGVV and the abundance and distribution of C. capitata. It is recommended that an in-depth spatio-temporal analysis be carried out to better understand the geographical distribution of trap catches in the study area.
    Keywords Ceratitis capitata ; Citrus ; cultivars ; databases ; fruit crops ; fruit flies ; fruits ; geographic information systems ; geographical distribution ; integrated pest management ; pome fruits ; small fruits ; spatial distribution ; spatial variation ; sterile insect technique ; stone fruits ; temporal variation ; trapping ; traps ; wine grapes ; South Africa
    Language English
    Dates of publication 2019-0425
    Size p. 97-113.
    Publishing place Entomological Society of Southern Africa
    Document type Article
    ZDB-ID 2114779-6
    ISSN 1021-3589
    ISSN 1021-3589
    DOI 10.4001/003.027.0097
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Torsion of a mesenteric lymphatic cyst.

    ADDISON, N V

    British medical journal

    2003  Volume 1, Issue 4823, Page(s) 1316

    MeSH term(s) Humans ; Lymphangioma ; Lymphocele ; Mesenteric Cyst ; Mesentery ; Neoplasms
    Language English
    Publishing date 2003-07-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 80088-0
    ISSN 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146
    ISSN 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146
    DOI 10.1136/bmj.1.4823.1316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Surgery of the colon and rectum

    Pichlmaier, Heinz / Addison, N. V.

    75 tables ; joint meeting of the Section of Proctology, The Royal Society of Medicine, London, Köln, 1978

    1980  

    Institution Royal Society of Medicine / Section of Proctology
    Author's details ed. by H. Pichlmaier ... With contrib. by N. V. Addison
    Keywords COLON / SURGERY / CONGRESSES ; RECTUM / SURGERY / CONGRESSES
    Size X, 146 S. : Ill.
    Publisher Thieme u.a.
    Publishing place Stuttgart u.a.
    Document type Book
    HBZ-ID HT000395498
    ISBN 3-13-588201-2 ; 0-913258-88-1 ; 978-3-13-588201-7 ; 978-0-913258-88-0
    Database Catalogue ZB MED Medicine, Health

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