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  1. Article ; Online: Response to the letter to the editor EUPC-D-23-00318 of Jesús Daniel Martínez-Alday.

    Brignole, Michele

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2023  Volume 25, Issue 7

    MeSH term(s) Humans ; Syncope, Vasovagal ; Reflex
    Language English
    Publishing date 2023-06-26
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euad178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: About syncopal recurrences in Biosync trial.

    Brignole, Michele

    European heart journal

    2021  Volume 42, Issue 43, Page(s) 4499–4500

    MeSH term(s) Humans ; Recurrence ; Syncope ; Tilt-Table Test
    Language English
    Publishing date 2021-06-18
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehab383
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  3. Article ; Online: Establishing the Efficacy of Midodrine to Prevent Vasovagal Syncope.

    Brignole, Michele

    Annals of internal medicine

    2021  Volume 174, Issue 10, Page(s) 1460–1461

    MeSH term(s) Humans ; Midodrine/therapeutic use ; Syncope, Vasovagal/prevention & control
    Chemical Substances Midodrine (6YE7PBM15H)
    Language English
    Publishing date 2021-08-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/M21-2859
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  4. Article ; Online: Different techniques of venous access for CIEDs: advantages and disadvantages.

    Brignole, Michele / Deharo, Jean-Claude

    European heart journal

    2023  Volume 44, Issue 46, Page(s) 4859–4861

    MeSH term(s) Humans ; Venous Cutdown ; Axillary Vein ; Pacemaker, Artificial/adverse effects ; Defibrillators, Implantable/adverse effects ; Punctures ; Ultrasonography, Interventional
    Language English
    Publishing date 2023-11-10
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad749
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  5. Book: Syncope

    Brignole, Michele / Benditt, David G.

    an evidence-based approach

    2011  

    Author's details Michele Brignole ; David G. Benditt
    Language English
    Size XVII, 344 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT016748420
    ISBN 978-0-85729-200-1 ; 0-85729-200-5 ; 9780857292018 ; 0857292013
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2011 A 1099 order for loan Magazin

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  6. Article ; Online: Mechanism-based therapy of non-cardiac syncope: a practical guide.

    Brignole, Michele / Rivasi, Giulia / Fedorowski, Artur

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2024  Volume 26, Issue 4

    Abstract: The term non-cardiac syncope includes all forms of syncope, in which primary intrinsic cardiac mechanism and non-syncopal transient loss of consciousness can be ruled out. Reflex syncope and orthostatic hypotension are the most frequent aetiologies of ... ...

    Abstract The term non-cardiac syncope includes all forms of syncope, in which primary intrinsic cardiac mechanism and non-syncopal transient loss of consciousness can be ruled out. Reflex syncope and orthostatic hypotension are the most frequent aetiologies of non-cardiac syncope. As no specific therapy is effective for all types of non-cardiac syncope, identifying the underlying haemodynamic mechanism is the essential prerequisite for an effective personalized therapy and prevention of syncope recurrences. Indeed, choice of appropriate therapy and its efficacy are largely determined by the syncope mechanism rather than its aetiology and clinical presentation. The two main haemodynamic phenomena leading to non-cardiac syncope include either profound hypotension or extrinsic asystole/pronounced bradycardia, corresponding to two different haemodynamic syncope phenotypes, the hypotensive and bradycardic phenotypes. The choice of therapy-aimed at counteracting hypotension or bradycardia-depends on the given phenotype. Discontinuation of blood pressure-lowering drugs, elastic garments, and blood pressure-elevating agents such as fludrocortisone and midodrine are the most effective therapies in patients with hypotensive phenotype. Cardiac pacing, cardioneuroablation, and drugs preventing bradycardia such as theophylline are the most effective therapies in patients with bradycardic phenotype of extrinsic cause.
    MeSH term(s) Humans ; Bradycardia/diagnosis ; Bradycardia/therapy ; Bradycardia/complications ; Syncope/diagnosis ; Syncope/etiology ; Syncope/therapy ; Syncope, Vasovagal/diagnosis ; Syncope, Vasovagal/therapy ; Hypotension ; Hypotension, Orthostatic/complications
    Language English
    Publishing date 2024-03-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euae073
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  7. Article ; Online: 'Ten Commandments' of ESC Syncope Guidelines 2018: The new European Society of Cardiology (ESC) Clinical Practice Guidelines for the diagnosis and management of syncope were launched 19 March 2018 at EHRA 2018 in Barcelona.

    Brignole, Michele

    European heart journal

    2018  Volume 39, Issue 21, Page(s) 1870–1871

    Language English
    Publishing date 2018-07-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehy210
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  8. Article ; Online: Hospital admission for syncope evaluation: Can we see the forest for the trees?

    Shen, Win-Kuang / Brignole, Michele

    Heart rhythm

    2022  Volume 19, Issue 10, Page(s) 1723–1724

    MeSH term(s) Emergency Service, Hospital ; Hospitalization ; Hospitals ; Humans ; Syncope/diagnosis ; Syncope/etiology ; Syncope/therapy
    Language English
    Publishing date 2022-06-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2022.06.023
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  9. Article ; Online: Left bundle branch area pacing in perspective.

    Brignole, Michele / Sutton, Richard

    European heart journal

    2022  Volume 43, Issue 40, Page(s) 4174–4176

    MeSH term(s) Humans ; Cardiac Pacing, Artificial ; Bundle-Branch Block/therapy
    Language English
    Publishing date 2022-08-04
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehac447
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  10. Article ; Online: Pacing for vasovagal syncope: Tips for use in practice.

    Morillo, Carlos A / Brignole, Michele

    Autonomic neuroscience : basic & clinical

    2022  Volume 241, Page(s) 102998

    Abstract: Vasovagal syncope (VVS) continues to be the most frequent cause of syncope in all age groups. Recent randomized double-blinded trials (RCTs) provide further support for pacing in selected cases of patients with recurrent refractory VVS with significant ... ...

    Abstract Vasovagal syncope (VVS) continues to be the most frequent cause of syncope in all age groups. Recent randomized double-blinded trials (RCTs) provide further support for pacing in selected cases of patients with recurrent refractory VVS with significant cardio-inhibitory response either documented spontaneously or induced during head-up tilt testing (HUTT). Cardiac pacing is the only therapy of proven efficacy for the predominant cardio-inhibitory phenotype of vasovagal (reflex) syncope; however, several questions regarding the best candidates remain. The current review focuses on practical tips for use of cardiac pacing in practice.
    MeSH term(s) Cardiac Pacing, Artificial/adverse effects ; Humans ; Research Design ; Syncope/complications ; Syncope, Vasovagal/therapy ; Tilt-Table Test/adverse effects
    Language English
    Publishing date 2022-06-02
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2020105-9
    ISSN 1872-7484 ; 1566-0702
    ISSN (online) 1872-7484
    ISSN 1566-0702
    DOI 10.1016/j.autneu.2022.102998
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