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  1. Article ; Online: Reducing Immunoreactivity of Gluten Peptides by Probiotic Lactic Acid Bacteria for Dietary Management of Gluten-Related Diseases.

    Leszczyńska, Joanna / Szczepankowska, Agnieszka K / Majak, Iwona / Mańkowska, Dorota / Smolińska, Beata / Ścieszka, Sylwia / Diowksz, Anna / Cukrowska, Bożena / Aleksandrzak-Piekarczyk, Tamara

    Nutrients

    2024  Volume 16, Issue 7

    Abstract: Immunoreactive gluten peptides that are not digested by peptidases produced by humans can trigger celiac disease, allergy and non-celiac gluten hypersensitivity. The aim of this study was to evaluate the ability of selected probiotic strains to hydrolyze ...

    Abstract Immunoreactive gluten peptides that are not digested by peptidases produced by humans can trigger celiac disease, allergy and non-celiac gluten hypersensitivity. The aim of this study was to evaluate the ability of selected probiotic strains to hydrolyze immunoreactive gliadin peptides and to identify peptidase-encoding genes in the genomes of the most efficient strains. Residual gliadin immunoreactivity was measured after one- or two-step hydrolysis using commercial enzymes and bacterial peptidase preparations by G12 and R5 immunoenzymatic assays. Peptidase preparations from
    MeSH term(s) Humans ; Glutens ; Lactobacillales/genetics ; Gliadin ; Peptides ; Peptide Hydrolases ; Endopeptidases ; Hypersensitivity ; Probiotics
    Chemical Substances Glutens (8002-80-0) ; Gliadin (9007-90-3) ; Peptides ; Peptide Hydrolases (EC 3.4.-) ; Endopeptidases (EC 3.4.-)
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16070976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Review paper Post-Lyme disease syndrome

    Joanna Ścieszka / Józefa Dąbek / Paweł Cieślik

    Rheumatology, Vol 53, Iss 1, Pp 46-

    2015  Volume 48

    Abstract: About 10% of patients with Lyme disease continue to experience musculoskeletal pain and cognitive dysfunction after recommended antibiotic treatment. This condition is called post-Lyme disease syndrome (PLDS) or post-treatment Lyme disease syndrome. ... ...

    Abstract About 10% of patients with Lyme disease continue to experience musculoskeletal pain and cognitive dysfunction after recommended antibiotic treatment. This condition is called post-Lyme disease syndrome (PLDS) or post-treatment Lyme disease syndrome. These two terms are used interchangeably. The pathogenesis of PLDS has been controversial. The hypothesis that patients with PLDS may harbor hidden reservoirs of Borrelia burgdorferi after their initial antibiotic treatment is difficult to accept. The prospective, double-blind studies contradict this point of view. Also, recently published research applying xenodiagnosis to PLDS supports the opinion that PLDS most likely has an autoimmune background. Lengthy courses of antibiotics are not justified in patients with PLDS because of the lack of benefit, and they are fraught with hazards. Most patients with PLDS recover from persistent symptoms with time. However, it can take months before they feel completely well.
    Keywords Lyme disease ; Borrelia burgdorferi ; xenodiagnosis ; post-Lyme disease syndrome ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2015-04-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Abnormal portal vein waveform as an indicator of constrictive pericarditis – a case report

    Joanna Ścieszka / Józefa Dąbek / Paweł Cieślik

    Journal of Ultrasonography, Vol 15, Iss 61, Pp 227-

    2015  Volume 230

    Abstract: We report a case of a 17-year-old patient referred to our outpatient Doppler Department due to clinical suspicion of liver cirrhosis. The patient presented with non-specifi c symptoms, such as malaise, pain in the right subcostal region, peripheral ... ...

    Abstract We report a case of a 17-year-old patient referred to our outpatient Doppler Department due to clinical suspicion of liver cirrhosis. The patient presented with non-specifi c symptoms, such as malaise, pain in the right subcostal region, peripheral oedema. Until then, diagnostic imaging, including echocardiography was inconclusive. We performed the Doppler sonography of the portal system, which revealed normal diameter of the portal vein with abnormal, phasic and markedly pulsatile waveform. Hepatic veins distention with pathological reverse fl ow during systole was reported. Additionally, inferior vena cava was dilated and remained unchanged through the respiratory cycle. Basing on the above image a heart disease, which had not been taken into differential diagnosis before, was suggested. The following echocardiography, together with computed tomography, enabled a diagnosis of constrictive pericarditis. Successful pericardiotomy was performed. Such a complicated diagnostics happened to demonstrate an uncommon example of the use of portal vein waveform in making the proper cardiologic diagnosis.
    Keywords portal system ; Doppler method ; constrictive pericarditis ; Medicine (General) ; R5-920 ; Medical technology ; R855-855.5
    Subject code 610
    Language English
    Publishing date 2015-06-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Health effects of arsenic environmental pollution

    Anna Skoczyńska / Anna Wojakowska / Barbara Turczyn / Joanna Banaś / Bartosz Ścieszka / Piotr Banaś / Marta Skoczyńska

    Medycyna Środowiskowa, Vol 21, Iss 3, Pp 34-

    2018  Volume 42

    Abstract: Introduction. Arsenic air concentrations are relatively low and inhalation route plays only a minor role in the total exposure. On a global scale, elevated arsenic air concentrations are registered in proximity to anthropogenic emission sources, mainly ... ...

    Abstract Introduction. Arsenic air concentrations are relatively low and inhalation route plays only a minor role in the total exposure. On a global scale, elevated arsenic air concentrations are registered in proximity to anthropogenic emission sources, mainly copper mines. The majority of studies concern occupational exposure but not other types of exposure. Aim: The purpose of this study is to present health effects of occupational and non-occupational exposure to arsenic. Material and methods. A Pub-Med database search has been performed, using keywords such as arsenic-air-toxicity/carcinogenicity, and their combinations. Results: In the years 1977–2015, 54 epidemiologic studies concerning arsenic effects on population health were published. Only in four of them were arsenic air concentrations (0.5–21.6 mg/m3) presented together with arsenic inhalation effects, mainly respiratory and cardiovascular changes in copper mines workers. An increased mortality due to lung cancer, cardiovascular diseases, hematologic cancers, and liver cirrhosis in comparison to workers not occupationally exposed to arsenic was shown. Environmental exposure to arsenic contained in air (at 0.4–30 ng/m3 concentrations) equals about 40–90 ng of arsenic inhaled daily by exposed humans. In areas free from pollution, the inhaled dose may be 50 ng and less. Exposure to arsenic even at such low doses may result in inflammation of the respiratory tract, dyspnea, and nasal septum perforation. Another issue is arsenic carcinogenicity. Conclusions. In populations exposed to arsenic emitted by copper industry, toxic and carcinogenic arsenic effects should be monitored.
    Keywords arsenic ; inhalation route ; toxicity ; carcinogenicity ; Environmental technology. Sanitary engineering ; TD1-1066 ; Medicine ; R
    Subject code 333
    Language English
    Publishing date 2018-09-01T00:00:00Z
    Publisher Institute of Occupational Medicine and Environmental Health
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Abnormal portal vein waveform as an indicator of constrictive pericarditis - a case report.

    Ścieszka, Joanna / Dąbek, Józefa / Cieślik, Paweł

    Journal of ultrasonography

    2015  Volume 15, Issue 61, Page(s) 227–230

    Abstract: We report a case of a 17-year-old patient referred to our outpatient Doppler Department due to clinical suspicion of liver cirrhosis. The patient presented with non-specific symptoms, such as malaise, pain in the right subcostal region, peripheral oedema. ...

    Abstract We report a case of a 17-year-old patient referred to our outpatient Doppler Department due to clinical suspicion of liver cirrhosis. The patient presented with non-specific symptoms, such as malaise, pain in the right subcostal region, peripheral oedema. Until then, diagnostic imaging, including echocardiography was inconclusive. We performed the Doppler sonography of the portal system, which revealed normal diameter of the portal vein with abnormal, phasic and markedly pulsatile waveform. Hepatic veins distention with pathological reverse flow during systole was reported. Additionally, inferior vena cava was dilated and remained unchanged through the respiratory cycle. Basing on the above image a heart disease, which had not been taken into differential diagnosis before, was suggested. The following echocardiography, together with computed tomography, enabled a diagnosis of constrictive pericarditis. Successful pericardiotomy was performed. Such a complicated diagnostics happened to demonstrate an uncommon example of the use of portal vein waveform in making the proper cardiologic diagnosis.
    Language English
    Publishing date 2015-06-30
    Publishing country Poland
    Document type Case Reports
    ZDB-ID 2843824-3
    ISSN 2084-8404
    ISSN 2084-8404
    DOI 10.15557/JoU.2015.0019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Post-Lyme disease syndrome.

    Ścieszka, Joanna / Dąbek, Józefa / Cieślik, Paweł

    Reumatologia

    2015  Volume 53, Issue 1, Page(s) 46–48

    Abstract: About 10% of patients with Lyme disease continue to experience musculoskeletal pain and cognitive dysfunction after recommended antibiotic treatment. This condition is called post-Lyme disease syndrome (PLDS) or post-treatment Lyme disease syndrome. ... ...

    Abstract About 10% of patients with Lyme disease continue to experience musculoskeletal pain and cognitive dysfunction after recommended antibiotic treatment. This condition is called post-Lyme disease syndrome (PLDS) or post-treatment Lyme disease syndrome. These two terms are used interchangeably. The pathogenesis of PLDS has been controversial. The hypothesis that patients with PLDS may harbor hidden reservoirs of Borrelia burgdorferi after their initial antibiotic treatment is difficult to accept. The prospective, double-blind studies contradict this point of view. Also, recently published research applying xenodiagnosis to PLDS supports the opinion that PLDS most likely has an autoimmune background. Lengthy courses of antibiotics are not justified in patients with PLDS because of the lack of benefit, and they are fraught with hazards. Most patients with PLDS recover from persistent symptoms with time. However, it can take months before they feel completely well.
    Language English
    Publishing date 2015
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 604151-6
    ISSN 0034-6233
    ISSN 0034-6233
    DOI 10.5114/reum.2015.50557
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 676: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Subcutaneous sarcoidosis on ultrasonography.

    Ścieszka, Joanna / Wojtala, Renata / Cieślik, Paweł / Lesiecka, Mieczysława / Papuga-Szela, Elżbieta

    Cutis

    2015  Volume 95, Issue 3, Page(s) E1–2

    MeSH term(s) Biopsy ; Female ; Forearm ; Humans ; Middle Aged ; Sarcoidosis/diagnostic imaging ; Sarcoidosis/pathology ; Skin Diseases/diagnostic imaging ; Skin Diseases/pathology ; Ultrasonography
    Language English
    Publishing date 2015-03
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 391840-3
    ISSN 0011-4162 ; 0151-9522
    ISSN 0011-4162 ; 0151-9522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1315: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 44: Show issues

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  8. Article: Moyamoya-like vascular pattern of the hepatic portal in primary sclerosing cholangitis associated with portal vein occlusion.

    Scieszka, Joanna / Ecieszka, Joanna / Hartleb, Marek / Pilch-Kowalczyk, Joanna / Papuga, Elzbieta / papuga, Elzbieta / Budzyńska, Agnieszka / Budzyñska, Agnieszka

    Ultraschall in der Medizin (Stuttgart, Germany : 1980)

    2007  Volume 28, Issue 4, Page(s) 341–344

    MeSH term(s) Arterial Occlusive Diseases/diagnostic imaging ; Cholestasis/diagnostic imaging ; Female ; Hepatic Artery/diagnostic imaging ; Humans ; Middle Aged ; Moyamoya Disease/diagnostic imaging ; Portal Vein/diagnostic imaging ; Ultrasonography ; Vascular Diseases/diagnostic imaging
    Language German
    Publishing date 2007-08
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 801064-x
    ISSN 1438-8782 ; 0172-4614 ; 1439-0914 ; 1431-4894
    ISSN (online) 1438-8782
    ISSN 0172-4614 ; 1439-0914 ; 1431-4894
    DOI 10.1055/s-2007-985539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1572: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Ultrasonography of the tongue in macroglossia – a case report

    Joanna Ścieszka / Sławomira Kyrcz-Krzemień / Paweł Cieślik / Dagmara Urbańska-Krawiec

    Journal of Ultrasonography, Vol 13, Iss 55, Pp 460-

    2013  Volume 463

    Abstract: This paper is an attempt to assess the usefulness of ultrasonography in the diagnosis of the enlargement of the tongue (macroglossia). The role of sonography in diagnosing local pathologies of the tongue, such as neoplasms, abscesses or granulomas, has ... ...

    Abstract This paper is an attempt to assess the usefulness of ultrasonography in the diagnosis of the enlargement of the tongue (macroglossia). The role of sonography in diagnosing local pathologies of the tongue, such as neoplasms, abscesses or granulomas, has been wellestablished for 20 years. Rarely is its usefulness considered with respect to diagnosing macroglossia with concomitant systemic diseases. The starting point of these considerations was the presented case of a 59-year-old patient with considerably enlarged tongue. The patient had difficulty speaking and ingesting meals. Moreover, he complained about swelling and pain in the carpal and proximal interphalangeal joints. Tongue ultrasound examination revealed blurred lingual structure with evident, irregular vascular pattern in the color Doppler. The obtained image helped to rule out local pathology of the tongue and directed our diagnostic considerations towards immunoglobulin-related diseases (deposition diseases). We believe that the presented ultrasound image of the tongue was helpful in the diagnostic process. Establishing the final, correct diagnosis was a particularly strenuous process. The suspicion of a deposition disease had been rejected during two previous stays in two hospitals. This was the consequence of a negative diagnostic test of staining tissue deposits with Congo red. An accurate diagnosis occurred to be a rare form of a deposition disease: lambda light chain disease with symptoms of amyloidosis. Such a diagnosis was based on a thorough hematological analysis. A high level of free lambda light chains in the serum was detected and the bone marrow biopsy showed 13% of plasma cells. The patient underwent chemotherapy.
    Keywords macroglossia ; light chain disease ; AL amyloidosis ; ultrasonography ; Doppler ultrasound examination ; Medicine (General) ; R5-920 ; Medical technology ; R855-855.5
    Subject code 610
    Language English
    Publishing date 2013-12-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article: Ultrasonography of the tongue in macroglossia - a case report.

    Ścieszka, Joanna / Kyrcz-Krzemień, Sławomira / Cieślik, Paweł / Urbańska-Krawiec, Dagmara

    Journal of ultrasonography

    2013  Volume 13, Issue 55, Page(s) 460–463

    Abstract: This paper is an attempt to assess the usefulness of ultrasonography in the diagnosis of the enlargement of the tongue (macroglossia). The role of sonography in diagnosing local pathologies of the tongue, such as neoplasms, abscesses or granulomas, has ... ...

    Abstract This paper is an attempt to assess the usefulness of ultrasonography in the diagnosis of the enlargement of the tongue (macroglossia). The role of sonography in diagnosing local pathologies of the tongue, such as neoplasms, abscesses or granulomas, has been well-established for 20 years. Rarely is its usefulness considered with respect to diagnosing macroglossia with concomitant systemic diseases. The starting point of these considerations was the presented case of a 59-year-old patient with considerably enlarged tongue. The patient had difficulty speaking and ingesting meals. Moreover, he complained about swelling and pain in the carpal and proximal interphalangeal joints. Tongue ultrasound examination revealed blurred lingual structure with evident, irregular vascular pattern in the color Doppler. The obtained image helped to rule out local pathology of the tongue and directed our diagnostic considerations towards immunoglobulin-related diseases (deposition diseases). We believe that the presented ultrasound image of the tongue was helpful in the diagnostic process. Establishing the final, correct diagnosis was a particularly strenuous process. The suspicion of a deposition disease had been rejected during two previous stays in two hospitals. This was the consequence of a negative diagnostic test of staining tissue deposits with Congo red. An accurate diagnosis occurred to be a rare form of a deposition disease: lambda light chain disease with symptoms of amyloidosis. Such a diagnosis was based on a thorough hematological analysis. A high level of free lambda light chains in the serum was detected and the bone marrow biopsy showed 13% of plasma cells. The patient underwent chemotherapy.
    Language English
    Publishing date 2013-12-30
    Publishing country Poland
    Document type Case Reports
    ZDB-ID 2843824-3
    ISSN 2084-8404
    ISSN 2084-8404
    DOI 10.15557/JoU.2013.0050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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