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  1. Article ; Online: General versus spinal anesthesia: are we asking the right question?

    Sondekoppam, Rakesh V / Ip, Vivian H Y

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2024  

    Title translation Anesthésie générale ou rachianesthésie : nous posons-nous la bonne question?
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Editorial
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-024-02695-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Promoting practice change towards environmentally sustainable health care: more than meets the eye.

    Ip, Vivian H Y / Shelton, Clifford L / Zimmermann, Gabrielle L

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2023  Volume 70, Issue 3, Page(s) 295–300

    Title translation Promouvoir un changement de pratique vers des soins de santé durables sur le plan environnemental: plus que des apparences.
    MeSH term(s) Humans ; Conservation of Natural Resources ; Delivery of Health Care
    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-022-02391-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Carbon Footprint of Anesthesia: Comment.

    Schroeder, Kristopher M / Özelsel, Timur / Ip, Vivian

    Anesthesiology

    2022  Volume 137, Issue 1, Page(s) 122

    MeSH term(s) Anesthesia ; Anesthesiology ; Carbon ; Carbon Dioxide ; Carbon Footprint
    Chemical Substances Carbon Dioxide (142M471B3J) ; Carbon (7440-44-0)
    Language English
    Publishing date 2022-05-04
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000004224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Primary Human Cell-Derived Extracellular Matrix from Decellularized Fibroblast Microtissues with Tissue-Dependent Composition and Microstructure.

    Fonseca, Vera C / Van, Vivian / Ip, Blanche C

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Human extracellular matrix (ECM) exhibits complex protein composition and architecture depending on tissue and disease state, which remains challenging to reverse engineer. One promising approach is based on cell-secreted ECM from human fibroblasts, ... ...

    Abstract Human extracellular matrix (ECM) exhibits complex protein composition and architecture depending on tissue and disease state, which remains challenging to reverse engineer. One promising approach is based on cell-secreted ECM from human fibroblasts, which can then be decellularized into an acellular biomaterial. However, fibroblasts initially seeded on rigid tissue culture plastic or biomaterial scaffolds experience aberrant mechanical cues that influence ECM deposition. Here, we show that engineered microtissues of primary human fibroblasts seeded in low-adhesion microwells can be decellularized to produce human, tissue-specific ECM. We investigate: 1) cardiac fibroblasts, as well as 2) lung fibroblasts from healthy, idiopathic fibrosis and chronic obstructive pulmonary disease donors. We demonstrate optimized culture and decellularization conditions, then characterize gene expression and protein composition. We further characterize ECM microstructure and mechanical properties. We envision that this method could be utilized for biomanufacturing of patient and tissue-specific ECM for organoid drug screening as well as implantable scaffolds.
    Impact: In this study, we demonstrate a method for preparing decellularized matrix using primary human fibroblasts with tissue and disease-specific features. We aggregate single cell dispersions into engineered tissues using low adhesion microwells and show culture conditions that promote ECM deposition. We demonstrate this approach for cardiac fibroblasts as well as lung fibroblasts (both normal and diseased). We systematically investigate tissue morphology, matrix architecture, and mechanical properties, along with transcriptomic and proteomic analysis. This approach should be widely applicable for generating personalized ECM with features of patient tissues and disease state, relevant for culturing patient cells ex vivo as well as implantation for therapeutic treatments.
    Language English
    Publishing date 2023-08-17
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.08.15.553420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Environmental Pain Approach (EPA): Sustainability in Chronic Pain Practice.

    Nelson, Ariana M / Kelleher, Deirdre C / Ip, Vivian / Narouze, Samer

    Pain medicine (Malden, Mass.)

    2022  Volume 24, Issue 6, Page(s) 573–575

    MeSH term(s) Humans ; Chronic Pain/therapy
    Language English
    Publishing date 2022-12-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2015903-1
    ISSN 1526-4637 ; 1526-2375
    ISSN (online) 1526-4637
    ISSN 1526-2375
    DOI 10.1093/pm/pnac185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Ambulatory total hip and knee arthroplasty: a literature review and perioperative considerations.

    Ip, Vivian H Y / Uppal, Vishal / Kwofie, Kwesi / Shah, Ushma / Wong, Patrick B Y

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2024  

    Abstract: Purpose: Total joint arthroplasty (TJA), particularly for the hip and knee, is one of the most commonly performed surgical procedures. The advancement/evolution of surgical and anesthesia techniques have allowed TJA to be performed on an ambulatory/same- ...

    Title translation Arthroplastie totale de la hanche et du genou en ambulatoire : revue de la littérature et considérations périopératoires.
    Abstract Purpose: Total joint arthroplasty (TJA), particularly for the hip and knee, is one of the most commonly performed surgical procedures. The advancement/evolution of surgical and anesthesia techniques have allowed TJA to be performed on an ambulatory/same-day discharge basis. In this Continuing Professional Development module, we synthesize the perioperative evidence that may aid the development of successful ambulatory TJA pathways.
    Source: We searched MEDLINE, Embase, CENTRAL, and the Cochrane Database of Systematic Reviews for ambulatory or fast-track TJA articles. In the absence of direct evidence for the ambulatory setting, we extrapolated the evidence from the in-patient TJA literature.
    Principal findings: Patient selection encompassing patient, medical, and social factors is fundamental for successful same-day discharge of patients following TJA. Evidence for the type of intraoperative anesthesia favours neuraxial technique for achieving same day discharge criteria and reduced perioperative complications. Availability of short-acting local anesthetic for neuraxial anesthesia would affect the anesthetic choice. Nonetheless, modern general anesthesia with multimodal analgesia and antithrombotics in a well selected population can be considered. Regional analgesia forms an integral part of the multimodal analgesia regime to reduce opioid consumption and facilitate same-day hospital discharge, reducing hospital readmission. For ambulatory total knee arthroplasty, a combination of adductor canal block with local anesthetic periarticular infiltration provided is a suitable regional analgesic regimen.
    Conclusion: Anesthesia for TJA has evolved as such that same-day discharge will become the norm for selected patients. It is essential to establish pathways for early discharge to prevent adverse effects and readmission in this population. As more data are generated from an increased volume of ambulatory TJA, more robust evidence will emerge for the ideal anesthetic components to optimize outcomes.
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-024-02699-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Absence of Evidence Is Not the Evidence of Absence: Clinical Consideration when Interpreting Guidelines for the COVID-19 Pandemic.

    Ip, Vivian / Sondekoppam, Rakesh

    Journal of the American College of Surgeons

    2020  Volume 231, Issue 3, Page(s) 407–408

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Operating Rooms ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1181115-8
    ISSN 1879-1190 ; 1072-7515
    ISSN (online) 1879-1190
    ISSN 1072-7515
    DOI 10.1016/j.jamcollsurg.2020.05.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Regional Anesthesia for Athletes Undergoing Upper Extremity Procedures: Techniques and Considerations.

    Potvin, Carole-Anne / Ip, Vivian H Y

    Clinics in sports medicine

    2022  Volume 41, Issue 2, Page(s) 203–217

    Abstract: Upper extremity injuries are frequent in athletes which may require surgeries. Regional anesthesia for postoperative analgesia is important to aid recovery, and peripheral nerve blocks for surgical anesthesia enable surgeries to be performed without ... ...

    Abstract Upper extremity injuries are frequent in athletes which may require surgeries. Regional anesthesia for postoperative analgesia is important to aid recovery, and peripheral nerve blocks for surgical anesthesia enable surgeries to be performed without general anesthetics and their associated adverse effects. The relevant nerve block approaches to anesthetize the brachial plexus for elbow, wrist and hand surgeries are discussed in this article. There is very limited margin for error when performing nerve blocks and multimodal monitoring approach to reduce harm are outlined. Lastly, the importance of obtaining informed consent prior to nerve block procedures should not be overlooked.
    MeSH term(s) Anesthesia, Conduction/methods ; Athletes ; Brachial Plexus/surgery ; Humans ; Nerve Block/methods ; Upper Extremity/surgery
    Language English
    Publishing date 2022-02-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 779944-5
    ISSN 1556-228X ; 0278-5919
    ISSN (online) 1556-228X
    ISSN 0278-5919
    DOI 10.1016/j.csm.2021.11.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: COVID-19 Pandemic: Negative-Pressure Tent During Atomization of Local Anesthetic for Awake Fiberoptic Intubation.

    Ip, Vivian / Tham, Christopher

    Anesthesia and analgesia

    2020  Volume 131, Issue 3, Page(s) e178–e179

    MeSH term(s) Anesthetics, Local ; Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Fiber Optic Technology ; Humans ; Intubation, Intratracheal ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Wakefulness
    Chemical Substances Anesthetics, Local
    Keywords covid19
    Language English
    Publishing date 2020-06-24
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000005066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cryoneurolysis and Peripheral Nerve Stimulation: Comment.

    Tsui, Ban C H / Sondekoppam, Rakesh V / Ip, Vivian

    Anesthesiology

    2021  Volume 134, Issue 5, Page(s) 817–818

    MeSH term(s) Acute Pain ; Humans ; Nerve Block ; Pain Management ; Peripheral Nerves ; Transcutaneous Electric Nerve Stimulation
    Language English
    Publishing date 2021-03-14
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000003739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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