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  1. Article ; Online: A Synchronous Hybrid Team-Based Learning Class: Why and How to Do It?

    Lee, Irene Cheng Jie / Wong, Peiyan / Goh, Suzanne Pei Lin / Cook, Sandy

    Medical science educator

    2022  Volume 32, Issue 3, Page(s) 697–702

    Abstract: COVID-19 pandemic has transformed much of the medical curriculum delivery from in person to online. Given that interpersonal interaction facilitates team cohesion and professional identity formation, prolonged online learning with minimal social ... ...

    Abstract COVID-19 pandemic has transformed much of the medical curriculum delivery from in person to online. Given that interpersonal interaction facilitates team cohesion and professional identity formation, prolonged online learning with minimal social interaction might impact these competencies in medical education. To mitigate the impact of prolonged social isolation, we conducted synchronous team-based learning (TBL) classes, where half the class is physically present and the other is connected via an online platform, termed hybrid TBL. We present practical tips in implementing hybrid TBL for educators teaching in large-sized classes, should conditions exist where not all students can attend in person.
    Language English
    Publishing date 2022-04-26
    Publishing country United States
    Document type Journal Article
    ISSN 2156-8650
    ISSN (online) 2156-8650
    DOI 10.1007/s40670-022-01538-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Academic coaching of medical students during the COVID-19 pandemic.

    Lee, Irene Cheng Jie / Koh, Huishan / Lai, Siang Hui / Hwang, Nian Chih

    Medical education

    2020  Volume 54, Issue 12, Page(s) 1184–1185

    MeSH term(s) COVID-19/epidemiology ; Education, Medical/organization & administration ; Humans ; Learning ; Mentoring/organization & administration ; Motivation ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 195274-2
    ISSN 1365-2923 ; 0308-0110
    ISSN (online) 1365-2923
    ISSN 0308-0110
    DOI 10.1111/medu.14272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Academic coaching of medical students during the COVID‐19 pandemic

    Lee, Irene Cheng Jie / Koh, Huishan / Lai, Siang Hui / Hwang, Nian Chih

    Medical Education ; ISSN 0308-0110 1365-2923

    2020  

    Keywords Education ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/medu.14272
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Academic Coaching of Medical Students During COVID-19

    Lee, Irene Cheng Jie / Koh, Huishan / Lai, Siang Hui / Hwang, Nian Chih

    Med. educ

    Abstract: Social distancing measures due to the COVID-19 pandemic has required many medical schools to adapt existing on-site medical education activities to delivery via online platforms. The sudden switch to a new, unfamiliar model of learning led to additional ... ...

    Abstract Social distancing measures due to the COVID-19 pandemic has required many medical schools to adapt existing on-site medical education activities to delivery via online platforms. The sudden switch to a new, unfamiliar model of learning led to additional challenges for students. We observed that students requiring academic support often had ineffective learning strategies, poor motivation, and suboptimal communication skills, all of which were magnified by home-based learning. We therefore established a virtual academic coaching programme to engage these students and to address specific challenges that arose from an adapted educational programme.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32531804
    Database COVID19

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  5. Article ; Online: From Trial to Implementation, Bringing Team-Based Learning Online-Duke-NUS Medical School's Response to the COVID-19 Pandemic.

    Jumat, Muhammad Raihan / Wong, Peiyan / Foo, Ke Xiang / Lee, Irene Cheng Jie / Goh, Suzanne Pei Lin / Ganapathy, Sashikumar / Tan, Thean Yen / Loh, Alwin Hwai Liang / Yeo, Yen Ching / Chao, Yinxia / Cheng, Lionel Tim-Ee / Lai, Siang Hui / Goh, Sok Hong / Compton, Scott / Hwang, Nian Chih

    Medical science educator

    2020  Volume 30, Issue 4, Page(s) 1649–1654

    Keywords covid19
    Language English
    Publishing date 2020-08-04
    Publishing country United States
    Document type Editorial
    ISSN 2156-8650
    ISSN (online) 2156-8650
    DOI 10.1007/s40670-020-01039-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Redesigning team-based learning facilitation for an online platform to deliver preclinical curriculum: A response to the COVID-19 pandemic.

    Wong, Peiyan / Jumat, Muhammad Raihan / Lee, Irene Cheng Jie / Foo, Ke Xiang / Goh, Suzanne Pei Lin / Ganapathy, Sashikumar / Lai, Siang Hui / Hwang, Nian Chih

    MedEdPublish (2016)

    2020  Volume 9, Page(s) 135

    Abstract: This article was migrated. The article was marked as recommended. Due to the increasing number of COVID-19 cases globally, and the need for critical containment, Duke-NUS Medical School, Singapore, moved all of its preclinical classes online, keeping ... ...

    Abstract This article was migrated. The article was marked as recommended. Due to the increasing number of COVID-19 cases globally, and the need for critical containment, Duke-NUS Medical School, Singapore, moved all of its preclinical classes online, keeping with national and university guidelines. The sudden move from face-to-face to online learning posed several challenges to the school's team-based learning (TBL) pedagogy. In TBL, student engagement is key to promote peer-to-peer learning. The educational faculty found that it was challenging to ensure student engagement through an online platform. Additionally, online TBL is heavily dependent on the use of technology. Technological and internet connectivity issues were potential obstacles to the learning process. This manuscript proposes practical tips for a facilitator of an online TBL class to engage learners in this new format. To overcome technical complications, a dedicated centralized administrative team managed the logistics of hosting TBL online. Working synergistically, the facilitator, and the administrative team were instrumental in recreating the learning environment of a face-to-face TBL in an online platform.
    Language English
    Publishing date 2020-06-25
    Publishing country Scotland
    Document type Journal Article
    ISSN 2312-7996
    ISSN (online) 2312-7996
    DOI 10.15694/mep.2020.000135.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics.

    Lee, Irene Cheng Jie / Leung, Thomas / Tan, Ivan

    The Journal of biological chemistry

    2014  Volume 289, Issue 39, Page(s) 26989–27003

    Abstract: Myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) has been shown to localize to the lamella of mammalian cells through its interaction with an adaptor protein, leucine repeat adaptor protein 35a (LRAP35a), which links it with myosin 18A ( ... ...

    Abstract Myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) has been shown to localize to the lamella of mammalian cells through its interaction with an adaptor protein, leucine repeat adaptor protein 35a (LRAP35a), which links it with myosin 18A (MYO18A) for activation of the lamellar actomyosin network essential for cell migration. Here, we report the identification of another adaptor protein LRAP25 that mediates MRCK association with LIM kinase 1 (LIMK1). The lamellipodium-localized LRAP25-MRCK complex is essential for the regulation of local LIMK1 and its downstream F-actin regulatory factor cofilin. Functionally, inhibition of either MRCK or LRAP25 resulted in a marked suppression of LIMK1 activity and down-regulation of cofilin phosphorylation in response to aluminum fluoride induction in B16-F1 cells, which eventually resulted in deregulation of lamellipodial F-actin and reorganization of cytoskeletal structures causing defects in cell polarization and motility. These biochemical and functional characterizations thus underline the functional relevance of the LRAP25-MRCK complex in LIMK1-cofilin signaling and the importance of LRAP adaptors as key determinants of MRCK cellular localization and downstream specificities.
    MeSH term(s) Actin Depolymerizing Factors/genetics ; Actin Depolymerizing Factors/metabolism ; Actins/genetics ; Actins/metabolism ; Aluminum Compounds/pharmacology ; Animals ; COS Cells ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Movement/physiology ; Chlorocebus aethiops ; Down-Regulation/drug effects ; Down-Regulation/physiology ; Fluorides/pharmacology ; Gene Expression Regulation, Enzymologic/drug effects ; Gene Expression Regulation, Enzymologic/physiology ; Humans ; Lim Kinases/biosynthesis ; Lim Kinases/genetics ; Multiprotein Complexes/genetics ; Multiprotein Complexes/metabolism ; Myotonin-Protein Kinase/genetics ; Myotonin-Protein Kinase/metabolism ; Protein-Serine-Threonine Kinases/genetics ; Protein-Serine-Threonine Kinases/metabolism ; Pseudopodia/genetics ; Pseudopodia/metabolism ; Rats ; Receptors, Virus/genetics ; Receptors, Virus/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology
    Chemical Substances Actin Depolymerizing Factors ; Actins ; Aluminum Compounds ; FAM89B protein, human ; Multiprotein Complexes ; Receptors, Virus ; CDC42BPA protein, human (EC 2.7.1.-) ; Cdc42bpa protein, rat (EC 2.7.11.1) ; LIMK1 protein, human (EC 2.7.11.1) ; Lim Kinases (EC 2.7.11.1) ; Limk1 protein, rat (EC 2.7.11.1) ; Myotonin-Protein Kinase (EC 2.7.11.1) ; Protein-Serine-Threonine Kinases (EC 2.7.11.1) ; Fluorides (Q80VPU408O) ; aluminum fluoride (Z77H3IKW94)
    Language English
    Publishing date 2014-08-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1074/jbc.M114.588079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Redesigning team-based learning facilitation for an online platform to deliver preclinical curriculum

    Peiyan Wong / Muhammad Raihan Jumat / Irene Cheng Jie Lee / Ke Xiang Foo / Suzanne Pei Lin Goh / Sashikumar Ganapathy / Siang Hui Lai / Nian Chih Hwang

    MedEdPublish, Vol 9, Iss

    A response to the COVID-19 pandemic

    2020  Volume 1

    Abstract: Due to the increasing number of COVID-19 cases globally, and the need for critical containment, Duke-NUS Medical School, Singapore, moved all of its preclinical classes online, keeping with national and university guidelines. The sudden move from face-to- ...

    Abstract Due to the increasing number of COVID-19 cases globally, and the need for critical containment, Duke-NUS Medical School, Singapore, moved all of its preclinical classes online, keeping with national and university guidelines. The sudden move from face-to-face to online learning posed several challenges to the school's team-based learning (TBL) pedagogy. In TBL, student engagement is key to promote peer-to-peer learning. The educational faculty found that it was challenging to ensure student engagement through an online platform. Additionally, online TBL is heavily dependent on the use of technology. Technological and internet connectivity issues were potential obstacles to the learning process. This manuscript proposes practical tips for a facilitator of an online TBL class to engage learners in this new format. To overcome technical complications, a dedicated centralized administrative team managed the logistics of hosting TBL online. Working synergistically, the facilitator, and the administrative team were instrumental in recreating the learning environment of a face-to-face TBL in an online platform.
    Keywords eLearning ; Remote Learning ; Flipped Classroom ; Home-Based Learning ; Special aspects of education ; LC8-6691 ; Medicine ; R ; covid19
    Subject code 028 ; 370
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher F1000 Research Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: From Trial to Implementation, Bringing Team-Based Learning Online-Duke-NUS Medical School's Response to the COVID-19 Pandemic

    Jumat, Muhammad Raihan / Wong, Peiyan / Foo, Ke Xiang / Lee, Irene Cheng Jie / Goh, Suzanne Pei Lin / Ganapathy, Sashikumar / Tan, Thean Yen / Loh, Alwin Hwai Liang / Yeo, Yen Ching / Chao, Yinxia / Cheng, Lionel Tim-Ee / Lai, Siang Hui / Goh, Sok Hong / Compton, Scott / Hwang, Nian Chih

    Med Sci Educ

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #705728
    Database COVID19

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