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  1. Article ; Online: Access to Telemedicine-Are We Doing All That We Can during the COVID-19 Pandemic?

    Rajasekaran, Karthik

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2020  Volume 163, Issue 1, Page(s) 104–106

    Abstract: The COVID-19 pandemic has resulted in physicians having to switch from in office visits to telemedicine. Unfortunately, physicians and patients did not have adequate time to anticipate barriers to its implementation. Over the last month, one of the major ...

    Abstract The COVID-19 pandemic has resulted in physicians having to switch from in office visits to telemedicine. Unfortunately, physicians and patients did not have adequate time to anticipate barriers to its implementation. Over the last month, one of the major problems has been patient access to telemedicine. Many patients do not own a smartphone or have broadband access. This "digital divide" is not fair to our patients in need-especially those with a cancer diagnosis. Patients deserve access to care. We need to implore insurance companies to provide tablets with wireless capabilities to patients in need.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Disease Transmission, Infectious/prevention & control ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Telemedicine/methods
    Keywords covid19
    Language English
    Publishing date 2020-05-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1177/0194599820925049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Dysphagia in Head and Neck Cancer.

    Lakshmipathy, Deepak / Allibone, Melissa / Rajasekaran, Karthik

    Otolaryngologic clinics of North America

    2024  

    Abstract: Dysphagia is a common symptom in patients with head and neck cancer that can significantly impact health outcomes and quality of life. The origin of dysphagia in these patients is often multifactorial, making diagnosis and management especially complex. ... ...

    Abstract Dysphagia is a common symptom in patients with head and neck cancer that can significantly impact health outcomes and quality of life. The origin of dysphagia in these patients is often multifactorial, making diagnosis and management especially complex. The evaluating otolaryngologist should be well versed with the patient's neoplasm, comorbidities, and treatment history alongside dysphagia-specific imaging modalities. Management is often dynamic, requiring frequent monitoring, interprofessional collaboration, and a variety of supportive and invasive measures to achieve optimal outcomes.
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 417489-6
    ISSN 1557-8259 ; 0030-6665
    ISSN (online) 1557-8259
    ISSN 0030-6665
    DOI 10.1016/j.otc.2024.02.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Delayed in diagnosis of upper aerodigestive tract cancers: A comprehensive review of medical malpractice cases.

    Fritz, Christian / Rajasekaran, Karthik

    Head & neck

    2023  Volume 45, Issue 7, Page(s) 1782–1789

    Abstract: Background: Factors that prompt litigation and influence outcomes for malpractice cases involving cancers of the upper aerodigestive tract are incompletely described.: Methods: Westlaw, a national legal database, was searched for medical malpractice ... ...

    Abstract Background: Factors that prompt litigation and influence outcomes for malpractice cases involving cancers of the upper aerodigestive tract are incompletely described.
    Methods: Westlaw, a national legal database, was searched for medical malpractice claims related to upper aerodigestive tract cancer for all years available.
    Results: Of the 122 cases meeting inclusion criteria, 106 (86.9%) involved allegations of failure to diagnose or delay in diagnosis. Tongue, larynx, and nasopharynx cancers were more frequently litigated than would be expected based on their incidence (tongue, 38.7% of aerodigestive tract litigation vs. 26.9% of aerodigestive tract cancers; larynx, 33.0% vs. 22.3%; nasopharynx, 10.4% vs. 4.6%). Payouts were made in over half of diagnosis failure lawsuits (56.6%), which carried an average award of $2840690 [IQR 850219-2537509].
    Conclusions: An awareness of litigation on cancers of the upper aerodigestive tract holds the potential to improve patient care and help otolaryngologists avoid potential risks for litigation.
    MeSH term(s) Humans ; United States ; Malpractice ; Neoplasms ; Databases, Factual
    Language English
    Publishing date 2023-05-05
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.27390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Survival Impact of Elective Neck Dissection and Adjuvant Radiation in N0 High-Grade Mucoepidermoid Carcinoma.

    Panara, Kush / Sangal, Neel / Lakshmipathy, Deepak / Rajasekaran, Karthik

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2024  

    Abstract: Objective: We aim to evaluate the role of elective neck dissection (END) and adjuvant radiation on survival in N0 high-grade mucoepidermoid carcinoma (MEC).: Study design: Retrospective cohort study.: Setting: National Cancer Institute's ... ...

    Abstract Objective: We aim to evaluate the role of elective neck dissection (END) and adjuvant radiation on survival in N0 high-grade mucoepidermoid carcinoma (MEC).
    Study design: Retrospective cohort study.
    Setting: National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database.
    Methods: All patients diagnosed with high-grade MEC with node-negative disease (N0) from 2004 to 2018 were included. Demographic, clinicopathologic, treatment, and outcomes were analyzed. Kaplan-Meier survival curves were used to evaluate 5-year disease-specific survival (DSS) and 5-year overall survival (OS). Multivariate Cox regression analysis was used to control for confounders.
    Results: A total of 310 patients with high-grade MEC and N0 (clinical and pathologic) disease were identified. The parotid was the most common primary site (266, 86%). Of included patients, 133 (42.9%) were T3-T4 tumors and 212 (68%) received adjuvant radiation. END was performed on 223 (71.9%) of cases. END in T3-T4 high-grade MEC led to significant improvements in DSS (74.3% vs 34.0%, P < .01) and OS (55.2% vs 20.5%, P < .01) as compared to no END. Subanalysis shows that in patients who received neck dissections and were pathologic N0, adjuvant radiation had no impact on DSS (84.0% vs 72.1%, P = .45) and OS (52.1% vs 55.8%, P = .91). Benefits persisted when controlling for confounders using multivariate Cox proportional regression.
    Conclusion: Patients with T3-T4 high-grade MEC who underwent END and found to be pathologically node-negative (pN0) had significantly improved 5-year DSS and 5-year OS than patients who were cN0 and did not undergo END. Importantly, although 68% of patients received adjuvant radiation, we show no benefit of this treatment modality on outcomes in pN0 high-grade MEC.
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1002/ohn.695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Access to Telemedicine-Are We Doing All That We Can during the COVID-19 Pandemic?

    Rajasekaran, Karthik

    Otolaryngol Head Neck Surg

    Abstract: The COVID-19 pandemic has resulted in physicians having to switch from in office visits to telemedicine. Unfortunately, physicians and patients did not have adequate time to anticipate barriers to its implementation. Over the last month, one of the major ...

    Abstract The COVID-19 pandemic has resulted in physicians having to switch from in office visits to telemedicine. Unfortunately, physicians and patients did not have adequate time to anticipate barriers to its implementation. Over the last month, one of the major problems has been patient access to telemedicine. Many patients do not own a smartphone or have broadband access. This "digital divide" is not fair to our patients in need-especially those with a cancer diagnosis. Patients deserve access to care. We need to implore insurance companies to provide tablets with wireless capabilities to patients in need.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #175747
    Database COVID19

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  6. Article ; Online: Access to Telemedicine—Are We Doing All That We Can during the COVID-19 Pandemic?

    Rajasekaran, Karthik

    Otolaryngology–Head and Neck Surgery

    2020  Volume 163, Issue 1, Page(s) 104–106

    Abstract: The COVID-19 pandemic has resulted in physicians having to switch from in office visits to telemedicine. Unfortunately, physicians and patients did not have adequate time to anticipate barriers to its implementation. Over the last month, one of the major ...

    Abstract The COVID-19 pandemic has resulted in physicians having to switch from in office visits to telemedicine. Unfortunately, physicians and patients did not have adequate time to anticipate barriers to its implementation. Over the last month, one of the major problems has been patient access to telemedicine. Many patients do not own a smartphone or have broadband access. This “digital divide” is not fair to our patients in need—especially those with a cancer diagnosis. Patients deserve access to care. We need to implore insurance companies to provide tablets with wireless capabilities to patients in need.
    Keywords Surgery ; Otorhinolaryngology ; covid19
    Language English
    Publisher SAGE Publications
    Publishing country us
    Document type Article ; Online
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1177/0194599820925049
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Development and validation of a pediatric model predicting trauma-related mortality.

    Evans, Mary / Rajasekaran, Karthik / Murala, Anish / Moreira, Alvaro

    BMC pediatrics

    2023  Volume 23, Issue 1, Page(s) 637

    Abstract: Objectives: To develop a prediction model of mortality in pediatric trauma-based injuries. Our secondary objective was to transform this model into a translational tool for clinical use.: Study design: A retrospective cohort study of children ≤ 18 ... ...

    Abstract Objectives: To develop a prediction model of mortality in pediatric trauma-based injuries. Our secondary objective was to transform this model into a translational tool for clinical use.
    Study design: A retrospective cohort study of children ≤ 18 years was derived from the National Trauma Data Bank between the years of 2007 to 2015. The goal was to identify clinical or physiologic variables that would serve as predictors for pediatric death. Data was split into a development cohort (80%) to build the model and then tested in an internal validation cohort (20%) and a temporal cohort. The area under the receiver operating characteristic curve (AUC) was assessed for the new model.
    Results: In 693,192 children, the mortality rate was 1.4% (n = 9,785). Most subjects were male (67%), White (65%), and incurred an unintentional injury (92%). The proposed model had an AUC of 96.4% (95% CI: 95.9%-96.9%). In contrast, the Injury Severity Score yielded an AUC of 92.9% (95% CI: 92.2%-93.6%), while the Revised Trauma Score resulted in an AUC of 95.0% (95% CI: 94.4%-95.6%).
    Conclusion: The TRAGIC + Model (Temperature, Race, Age, GCS, Injury Type, Cardiac-systolic blood pressure + Mechanism of Injury and Sex) is a new pediatric mortality prediction model that leverages variables easily obtained upon trauma admission.
    MeSH term(s) Humans ; Male ; Child ; Female ; Retrospective Studies ; Injury Severity Score ; Hospitalization ; ROC Curve ; Blood Pressure ; Wounds and Injuries ; Trauma Severity Indices
    Language English
    Publishing date 2023-12-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-023-04437-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Answering head and neck cancer questions: An assessment of ChatGPT responses.

    Wei, Kimberly / Fritz, Christian / Rajasekaran, Karthik

    American journal of otolaryngology

    2023  Volume 45, Issue 1, Page(s) 104085

    Abstract: Purpose: To examine and compare ChatGPT versus Google websites in answering common head and neck cancer questions.: Materials and methods: Commonly asked questions about head and neck cancer were obtained and inputted into both ChatGPT-4 and Google ... ...

    Abstract Purpose: To examine and compare ChatGPT versus Google websites in answering common head and neck cancer questions.
    Materials and methods: Commonly asked questions about head and neck cancer were obtained and inputted into both ChatGPT-4 and Google search engine. For each question, the ChatGPT response and first website search result were compiled and examined. Content quality was assessed by independent reviewers using standardized grading criteria and the modified Ensuring Quality Information for Patients (EQIP) tool. Readability was determined using the Flesch reading ease scale.
    Results: In total, 49 questions related to head and neck cancer were included. Google sources were on average significantly higher quality than ChatGPT responses (4.2 vs 3.6, p = 0.005). According to the EQIP tool, Google and ChatGPT had on average similar response rates per criterion (24.4 vs 20.5, p = 0.09) while Google had a significantly higher average score per question than ChatGPT (13.8 vs 11.7, p < 0.001) According to the Flesch reading ease scale, ChatGPT and Google sources were both considered similarly difficult to read (33.1 vs 37.0, p = 0.180) and at a college level (14.3 vs 14.2, p = 0.820.) CONCLUSION: ChatGPT responses were as challenging to read as Google sources, but poorer quality due to decreased reliability and accuracy in answering questions. Though promising, ChatGPT in its current form should not be considered dependable. Google sources are a preferred resource for patient educational materials.
    MeSH term(s) Humans ; Reproducibility of Results ; Head and Neck Neoplasms/therapy ; Search Engine
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.104085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Evaluation and Management of a Neck Mass.

    Chorath, Kevin / Rajasekaran, Karthik

    The Medical clinics of North America

    2021  Volume 105, Issue 5, Page(s) 827–837

    Abstract: Neck masses are common physical examination findings seen in the outpatient setting but identifying an underlying cause can be challenging. A careful medical history should be obtained, and a thorough physical examination should be performed, which will ... ...

    Abstract Neck masses are common physical examination findings seen in the outpatient setting but identifying an underlying cause can be challenging. A careful medical history should be obtained, and a thorough physical examination should be performed, which will guide the need for follow-up examination with imaging, biopsies, and specialist referrals. The goal of this article is to provide a working framework to evaluate and manage some of the most common causes of adult neck masses.
    MeSH term(s) Age Factors ; Biomarkers ; Biopsy, Fine-Needle ; Diagnosis, Differential ; Head and Neck Neoplasms/diagnosis ; Head and Neck Neoplasms/pathology ; Humans ; Neck/diagnostic imaging ; Neck/pathology ; Physical Examination ; Primary Health Care
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-07-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 215710-x
    ISSN 1557-9859 ; 0025-7125
    ISSN (online) 1557-9859
    ISSN 0025-7125
    DOI 10.1016/j.mcna.2021.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Oral Cavity Squamous Cell Carcinoma Presenting as an Isolated Nasal Mass in the Setting of a Fixed Implant-Supported Upper Denture.

    Civantos, Alyssa / Rajasekaran, Karthik

    The Journal of oral implantology

    2021  Volume 49, Issue 1, Page(s) 25–28

    Abstract: Proper staging and diagnosing of mucosal head and neck cancers is necessary given important differences in tumor behaviors that lead to different standards of treatment. We report the unusual case of a 65-year-old woman who is a former smoker with an ... ...

    Abstract Proper staging and diagnosing of mucosal head and neck cancers is necessary given important differences in tumor behaviors that lead to different standards of treatment. We report the unusual case of a 65-year-old woman who is a former smoker with an implant-supported upper denture who developed an isolated nasal mass on examination, which was confirmed after resection to be a squamous cell carcinoma originating from the hard palate. Although this is a rare scenario, an oral cavity cancer should be taken into consideration in the differential diagnosis of a nasal cavity mass in the setting of a fixed upper dental implant.
    MeSH term(s) Female ; Humans ; Aged ; Squamous Cell Carcinoma of Head and Neck ; Dental Implants ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/surgery ; Mouth Neoplasms/diagnosis ; Mouth Neoplasms/surgery ; Head and Neck Neoplasms ; Dentures ; Dental Prosthesis, Implant-Supported
    Chemical Substances Dental Implants
    Language English
    Publishing date 2021-08-19
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 448462-9
    ISSN 1548-1336 ; 0160-6972
    ISSN (online) 1548-1336
    ISSN 0160-6972
    DOI 10.1563/aaid-joi-D-20-00392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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