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Article ; Online: Outpatient medical management of later second trimester abortion (18-23.6 weeks) with procedural evacuation backup: A large case series.

Chandrasekaran, Sruthi / Ruggiero, Samantha / Goodrick, Gabrielle

Contraception: X

2024 Volume 6, Page(s) 100104

Abstract: Objective: Document the clinical outcomes of an outpatient medical management with procedural evacuation backup procedure for abortions between 18 weeks zero days to 23 weeks six days gestation.: Study design: We conducted a retrospective medical ... ...

Abstract	Objective: Document the clinical outcomes of an outpatient medical management with procedural evacuation backup procedure for abortions between 18 weeks zero days to 23 weeks six days gestation. Study design: We conducted a retrospective medical records review of adult patients who received mifepristone and repeated misoprostol for second trimester abortion with procedural evacuation backup at an Arizona clinic between October 2017 and November 2021. We extracted patient demographics; pregnancy and medical history; and preoperative, intraoperative, and postoperative data. We assessed abortion outcomes, including procedure timing, mode of completion (medication alone or medications and procedural evacuation), and safety. Results: All 359 patients had a complete abortion with 63.5% of patients completing with medication alone and 36.5% with procedural evacuation backup. The median time from first dose of misoprostol to fetal expulsion was six hours, among those who completed the abortion with medications alone. Of those who received procedural evacuation as backup, the median time for procedural evacuation was 10 minutes. The vast majority of patients (99.4%) did not have any adverse events. Two safety incidents (0.6%) occurred, a broad right ligament tear and a uterine rupture. Conclusion: Patients in one outpatient setting safely and effectively received medical management of second trimester abortion with procedural evacuation backup, and two thirds completed with medications alone. Implications: Outpatient settings may consider medical management of abortion between 18 and 24 weeks with procedural evacuation back-up as a safe, effective, and manageable second trimester abortion option. Additional research is needed on patient experience and satisfaction.
Language	English
Publishing date	2024-02-17
Publishing country	United States
Document type	Journal Article
ISSN	2590-1516
ISSN (online)	2590-1516
DOI	10.1016/j.conx.2024.100104
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Experiences with and unmet needs for medication abortion support: A qualitative study with US abortion support providers.

Seymour, Jane W / Ruggiero, Samantha / Ranker, Lynsie / Thompson, Terri-Ann

Perspectives on sexual and reproductive health

2024

Abstract: Introduction: Quality abortion care must be person-centered. Although academic literature has focused on full-spectrum and abortion doulas supporting instrumentation abortion (also referred to as procedural abortion) clients, clients undergoing ... ...

Abstract	Introduction: Quality abortion care must be person-centered. Although academic literature has focused on full-spectrum and abortion doulas supporting instrumentation abortion (also referred to as procedural abortion) clients, clients undergoing medication abortion remain understudied and may have unique needs. We aimed to understand United States (US) abortion support providers' perceptions of medication abortion clients' support needs by exploring which needs they address, which needs remain unmet, and how remote support provision might help address client needs. Methodology: Between April and October 2018, we conducted 60- to 90-min semi-structured, in-depth interviews by telephone with medication abortion support providers. The interviews focused on their experiences providing support to medication abortion clients in the US. We used a deductive thematic analysis approach. Results: We interviewed 16 abortion support providers affiliated with nine US-based organizations. Six participants provided in-person support to medication abortion clients, five provided remote support, and five provided both remote and in-person support. Both in-person and remote providers described offering support that addressed clients' informational, emotional, physical, spiritual, and logistical needs. Through participant narratives, we identified interwoven benefits and challenges to remote support care provision. Participants highlighted that most medication abortion clients did not have a support provider. Discussion: Participants revealed that abortion support providers, including remote support providers, can be a critical component of high-quality abortion care provision. More work is needed to ensure all abortion clients have access to support services as the abortion landscape in the US continues to evolve.
Language	English
Publishing date	2024-04-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2075205-2
ISSN	1931-2393 ; 1538-6341
ISSN (online)	1931-2393
ISSN	1538-6341
DOI	10.1111/psrh.12263
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Zs.A 943: Show issues

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bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Travel for later abortion in the USA: lived experiences, structural contributors and abortion fund support.

Makleff, Shelly / Blaylock, Rebecca / Ruggiero, Samantha / Key, Katherine / Chandrasekaran, Sruthi / Gerdts, Caitlin

Culture, health & sexuality

2023 Volume 25, Issue 12, Page(s) 1741–1757

Abstract: As abortion restrictions expand in the USA, pregnant people will continue to experience delays and be forced to travel for abortion. The study aims to describe later abortion travel experiences, understand structural factors influencing travel, and ... ...

Abstract	As abortion restrictions expand in the USA, pregnant people will continue to experience delays and be forced to travel for abortion. The study aims to describe later abortion travel experiences, understand structural factors influencing travel, and identify strategies to improve travel. This qualitative phenomenological study analyses data from 19 interviews with people who travelled at least 25 miles for abortion after the first trimester. Framework analysis used a structural violence lens. More than two-thirds of participants travelled interstate, and half received abortion fund support. Key considerations of travel include logistics, challenges during the journey, and physical and emotional recovery during and after travel. Restrictive laws, financial insecurity and anti-abortion infrastructure are forms of structural violence that created challenges and delays. Reliance on abortion funds facilitated access but also entailed uncertainty. Better resourced abortion funds could organise travel in advance, facilitate the travel of accompanying escorts, and tailor emotional support to reduce stress for those travelling. Clinical and practical support systems must be prepared to support people travelling for abortion, as later abortion and forced travel is increasing since the constitutional right to abortion in the USA was overturned. Findings can inform interventions to support the increasing number of people travelling for abortion.
MeSH term(s)	Pregnancy ; Female ; Humans ; Health Services Accessibility ; Abortion, Induced ; Travel ; Violence
Language	English
Publishing date	2023-03-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2023577-X
ISSN	1464-5351 ; 1369-1058
ISSN (online)	1464-5351
ISSN	1369-1058
DOI	10.1080/13691058.2023.2179666
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Article ; Online: Foley catheter and misoprostol for cervical preparation for second-trimester surgical abortion.

Chandrasekaran, Sruthi / Paul, Maureen / Ruggiero, Samantha / Monschauer, Emily / Blanchard, Kelly / Robinson, Yashica

Contraception

2021 Volume 104, Issue 4, Page(s) 437–441

Abstract: Objective: Document the effectiveness and safety of Foley balloon catheter and misoprostol use for cervical preparation before a same-day dilation and evacuation (D&E).: Study design: We conducted a retrospective medical records review of adult ... ...

Abstract	Objective: Document the effectiveness and safety of Foley balloon catheter and misoprostol use for cervical preparation before a same-day dilation and evacuation (D&E). Study design: We conducted a retrospective medical records review of adult patients with viable pregnancies at 18 weeks 0 days to 21 weeks 6 days gestation who received a same-day D&E at an Alabama clinic using a 30-cc Foley balloon catheter and misoprostol for cervical preparation from January 2016 through December 2017. Patients received misoprostol 800 mcg buccally at the time of Foley placement and then every 4 hours until the physician deemed that dilation/effacement was adequate to proceed with a D&E. We extracted patient demographics, pregnancy and medical history, and preoperative, intraoperative, and postoperative data. We primarily evaluated effectiveness (D&E completion within one procedure day). Our secondary outcomes included safety, time between misoprostol and procedure start time, length of D&E, recovery time, and number of doses of misoprostol provided. Results: Two hundred and ninety patient charts met our review criteria - all of whom had a complete abortion in one day. Only one safety incident, a cervical laceration, occurred (0.3% of all procedures). The median time between Foley placement and first misoprostol dose and the procedure start was 7.2 hours (2.9-12.6 hours; interquartile range [IQR] 6.2-8.4 hours); median procedure length was 12 minutes (2-40 minutes; IQR 10-15 minutes); and median recovery time 14 minutes (4-89 minutes; IQR 14-16 minutes). Most patients needed two doses of misoprostol (n = 258, 89%), and 11 (4%) needed three doses; 21 (7%) patients needed one dose of misoprostol. Conclusion: Patients in the mid-second trimester can effectively and safely undergo cervical preparation with a Foley balloon catheter and misoprostol to facilitate completion of same-day D&E. Implications: Foley balloon catheter use with misoprostol for cervical preparation for second-trimester abortion (the Robinson Foley protocol) is effective and safe and can be completed in one day when used by an experienced physician.
MeSH term(s)	Abortifacient Agents, Nonsteroidal ; Abortion, Induced ; Adult ; Catheters ; Female ; Humans ; Misoprostol ; Pregnancy ; Pregnancy Trimester, Second ; Retrospective Studies
Chemical Substances	Abortifacient Agents, Nonsteroidal ; Misoprostol (0E43V0BB57)
Language	English
Publishing date	2021-06-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	80106-9
ISSN	1879-0518 ; 0010-7824
ISSN (online)	1879-0518
ISSN	0010-7824
DOI	10.1016/j.contraception.2021.06.015
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Zs.A 629: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article: Patient and provider experiences using a site-to-site telehealth model for medication abortion.

Ruggiero, Samantha P / Seymour, Jane W / Thompson, Terri-Ann / Kohn, Julia E / Snow, Jennifer L / Grossman, Daniel / Fix, Laura

mHealth

2022 Volume 8, Page(s) 32

Abstract: Background: In the site-to-site telehealth for medication abortion model, patients visit a health center to meet with a remote clinician using telehealth technology. This model is safe, effective, and acceptable to patients and providers. The objective ... ...

Abstract	Background: In the site-to-site telehealth for medication abortion model, patients visit a health center to meet with a remote clinician using telehealth technology. This model is safe, effective, and acceptable to patients and providers. The objective of this study was to document the experiences of patients and providers using telehealth for medication abortion in Planned Parenthood health centers across different geographical contexts in the United States. Methods: We conducted in-depth interviews with Planned Parenthood medication abortion patients who either met with a clinician at the clinic via telehealth or in-person about their experiences receiving care. We also interviewed Planned Parenthood staff members about their experiences implementing telehealth for medication abortion at their health center. Results: We interviewed 29 patients who received care at Planned Parenthood health centers in five states. Both telehealth and in-person patients described positive interactions with health center staff and clinicians. The vast majority of telehealth patients said that they felt comfortable speaking with the clinician over telehealth and had no trouble using the telehealth technology. We interviewed 12 providers, including clinicians and administrative staff, who worked in seven states. Providers largely thought that telehealth for medication abortion expanded access to medication abortion. Conclusions: Across different locations, our findings indicate that patients found telehealth for medication abortion services to be highly acceptable and providers found that telehealth services may help improve medication abortion access. As the use of telehealth for medication abortion expands, future research should include additional measures of quality to ensure that services are acceptable across different identities and experiences, including age, race, gender, and income level.
Language	English
Publishing date	2022-10-30
Publishing country	China
Document type	Journal Article
ISSN	2306-9740
ISSN	2306-9740
DOI	10.21037/mhealth-22-12
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Volleyball Competition on Consecutive Days Modifies Jump Kinetics but Not Height.

Ruggiero, Luca / Pritchard, Samantha E / Warmenhoven, John / Bruce, Tavis / MacDonald, Kerry / Klimstra, Marc / McNeil, Chris J

International journal of sports physiology and performance

2022 Volume 17, Issue 5, Page(s) 711–719

Abstract: Purpose: In volleyball, jump execution is critical for the match outcome. Game-play-related neuromuscular impairments may manifest as decreased jump height (JH) or increased jump total duration, both of which are pivotal for performance. To investigate ... ...

Abstract	Purpose: In volleyball, jump execution is critical for the match outcome. Game-play-related neuromuscular impairments may manifest as decreased jump height (JH) or increased jump total duration, both of which are pivotal for performance. To investigate changes in JH and kinetics with game play, the authors conducted a prospective exploratory analysis using minimal-effect testing (MET) and equivalence testing with the 2 one-sided tests procedure, univariate, and bivariate functional principal component analysis, respectively. Methods: Twelve male varsity athletes completed 3-set matches on 2 consecutive days. Countermovement jumps were performed on a force platform immediately prematch and postmatch on days 1 and 2 and once on days 3 and 4. Results: Across sessions, JH was equivalent (P < .022, equivalence test), while total duration reported inconclusive changes (P > .227). After match 2, MET indicated that relative force at zero velocity (P = .036) decreased, while braking duration (P = .040) and time to peak force (P = .048) increased compared with baseline. With the first and second functional principal components, these alterations, together with decreased relative braking rate of force development (P = .092), were already evident after match 1. On day 4, MET indicated that relative peak force (P = .049), relative force at zero velocity (P = .023), and relative braking rate of force development (P = .021) decreased, whereas braking duration (P = .025) increased from baseline. Conclusions: Impairments in jump kinetics were evident from variables related to the countermovement-jump braking phase, while JH was equivalent. In addition to these experimental findings, the present research provides information for the choice of sample size and smallest effect size of interest when using MET and 1- and 2-dimensional analyses for countermovement-jump height and kinetics.
MeSH term(s)	Athletic Performance ; Humans ; Kinetics ; Male ; Muscle Strength ; Prospective Studies ; Volleyball
Language	English
Publishing date	2022-02-21
Publishing country	United States
Document type	Journal Article
ISSN	1555-0273
ISSN (online)	1555-0273
DOI	10.1123/ijspp.2021-0275
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A Quantitative Method for the Study of HIV-1 and Mycobacterium tuberculosis Coinfection.

Donnellan, Samantha / Pennington, Shaun H / Ruggiero, Alessandra / Martinez-Rodriguez, Carmen / Pouget, Marion / Thomas, Jordan / Ward, Steve A / Pollakis, Georgios / Biagini, Giancarlo A / Paxton, William A

The Journal of infectious diseases

2022 Volume 227, Issue 5, Page(s) 708–713

Abstract: Mycobacterium tuberculosis and human immunodeficiency virus-1 (HIV-1) syndemic interactions are a major global health concern. Despite the clinical significance of coinfection, our understanding of the cellular pathophysiology and the therapeutic ... ...

Abstract	Mycobacterium tuberculosis and human immunodeficiency virus-1 (HIV-1) syndemic interactions are a major global health concern. Despite the clinical significance of coinfection, our understanding of the cellular pathophysiology and the therapeutic pharmacodynamic impact of coinfection is limited. Here, we use single-round infectious HIV-1 pseudotyped viral particles expressing green fluorescent protein alongside M. tuberculosis expressing mCherry to study pathogenesis and treatment. We report that HIV-1 infection inhibited intracellular replication of M. tuberculosis and demonstrate the therapeutic activity of antiviral treatment (efavirenz) and antimicrobial treatment (rifampicin). The described method could be applied for detailed mechanistic studies to inform the development of novel treatment strategies.
MeSH term(s)	Humans ; Mycobacterium tuberculosis ; Tuberculosis/microbiology ; HIV-1 ; Coinfection/drug therapy ; Rifampin/therapeutic use ; HIV Infections/drug therapy
Chemical Substances	Rifampin (VJT6J7R4TR)
Language	English
Publishing date	2022-12-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3019-3
ISSN	1537-6613 ; 0022-1899
ISSN (online)	1537-6613
ISSN	0022-1899
DOI	10.1093/infdis/jiac491
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Uh II Zs.50: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Access to later abortion in the United States during COVID-19: challenges and recommendations from providers, advocates, and researchers.

Ruggiero, Samantha / Brandi, Kristyn / Mark, Alice / Paul, Maureen / Reeves, Matthew F / Schalit, Odile / Blanchard, Kelly / Key, Katherine / Chandrasekaran, Sruthi

Sexual and reproductive health matters

2020 Volume 28, Issue 1, Page(s) 1774185

MeSH term(s)	Abortion, Induced/legislation & jurisprudence ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Female ; Gestational Age ; Health Services Accessibility/legislation & jurisprudence ; Health Workforce ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pregnancy ; SARS-CoV-2 ; United States
Keywords	covid19
Language	English
Publishing date	2020-05-26
Publishing country	England
Document type	Journal Article
ISSN	2641-0397
ISSN (online)	2641-0397
DOI	10.1080/26410397.2020.1774185
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Access to later abortion in the United States during COVID-19: challenges and recommendations from providers, advocates, and researchers

Ruggiero, Samantha / Brandi, Kristyn / Mark, Alice / Paul, Maureen / Reeves, Matthew F / Schalit, Odile / Blanchard, Kelly / Key, Katherine / Chandrasekaran, Sruthi

Sex Reprod Health Matters

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32460663
Database	COVID19

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Article ; Online: Bronchiolitis and SARS-CoV-2.

Milani, Gregorio Paolo / Bollati, Valentina / Ruggiero, Luca / Bosis, Samantha / Pinzani, Raffaella Maria / Lunghi, Giovanna / Rota, Federica / Dioni, Laura / Luganini, Anna / Agostoni, Carlo / Marchisio, Paola

Archives of disease in childhood

2021 Volume 106, Issue 10, Page(s) 999–1001

Abstract: Background: It has been speculated that the SARS-CoV-2 was already widespread in western countries before February 2020.: Methods: We gauged this hypothesis by analysing the nasal swab of infants with either bronchiolitis or a non-infectious disease ... ...

Abstract	Background: It has been speculated that the SARS-CoV-2 was already widespread in western countries before February 2020. Methods: We gauged this hypothesis by analysing the nasal swab of infants with either bronchiolitis or a non-infectious disease admitted to the Ospedale Maggiore, Milan (one of the first epicentres of SARS-CoV-2 outbreak in Europe) from November 2019. Results: The SARS-CoV-2 RNA was never detected in 218 infants with bronchiolitis (95 females, median age 4.9 months) and 49 infants (22 females, median age 5.6 months) with a non-infectious disease between November 2019 and February 2020. On the contrary, two infants hospitalised for bronchiolitis between March and April 2020 tested positive for SARS-CoV-2. Conclusions: This study does not support the hypothesis that SARS-CoV-2 was already circulating among infants before the official outbreak of SARS-CoV-2 infection. However, it shows for the first time that SARS-CoV-2 might cause bronchiolitis requiring hospitalisation.
MeSH term(s)	Bronchiolitis/epidemiology ; Bronchiolitis/physiopathology ; Bronchiolitis/therapy ; Bronchiolitis/virology ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/physiopathology ; COVID-19 Testing/methods ; COVID-19 Testing/statistics & numerical data ; Causality ; Child Health Services/statistics & numerical data ; Comorbidity ; Female ; Hospitalization/statistics & numerical data ; Humans ; Infant ; Italy/epidemiology ; Male ; SARS-CoV-2/isolation & purification ; Severity of Illness Index
Language	English
Publishing date	2021-03-11
Publishing country	England
Document type	Journal Article
ZDB-ID	524-1
ISSN	1468-2044 ; 0003-9888 ; 1359-2998
ISSN (online)	1468-2044
ISSN	0003-9888 ; 1359-2998
DOI	10.1136/archdischild-2020-321108
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Zs.MA 3: Show issues

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