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  1. Article: PuCRZ1

    Han, Pengjie / Hua, Zhongyi / Zhao, Yuyang / Huang, Luqi / Yuan, Yuan

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1131605

    Abstract: Polyporus ... ...

    Abstract Polyporus umbellatus
    Language English
    Publishing date 2023-04-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1131605
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: E2/E3 and E3/E4 Genotypes of the Apolipoprotein E are Associated with Higher Risk of Diabetes Mellitus in Patients with Hypertension.

    Han, Wendao / Xiong, Nating / Zhong, Renkai / Pan, Zhongyi

    International journal of general medicine

    2023  Volume 16, Page(s) 5579–5586

    Abstract: Objective: Apolipoprotein E (APOE) plays an important role in the lipid metabolism. : Methods: The study included 808 hypertensive patients with DM and 1226 hypertensive patients without DM as controls. The : Results: The : Conclusion: ... ...

    Abstract Objective: Apolipoprotein E (APOE) plays an important role in the lipid metabolism.
    Methods: The study included 808 hypertensive patients with DM and 1226 hypertensive patients without DM as controls. The
    Results: The
    Conclusion: APOE
    Language English
    Publishing date 2023-11-24
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S438008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Nanoarchitectonics on residual carbon from gasification fine slag upon two step low temperature activation for application in supercapacitors.

    Zhu, Jiaqi / Song, Jinling / Han, Baobao / Gao, Jianmin / Liu, Zhongyi / Wang, Yao / Xin, Guoxiang

    iScience

    2023  Volume 26, Issue 11, Page(s) 108186

    Abstract: In this paper, the carbon electrode materials were prepared by the KOH- ... ...

    Abstract In this paper, the carbon electrode materials were prepared by the KOH-HNO
    Language English
    Publishing date 2023-10-12
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2023.108186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Bioinformatics reveals diagnostic potential of cuproptosis-related genes in the pathogenesis of sepsis

    Zhongyi Sun / Qiuyue Zhao / Jiahao Zhang / Yanan Hu / Jiachen Qu / Han Gao / Zhiyong Peng

    Heliyon, Vol 10, Iss 1, Pp e22664- (2024)

    1481  

    Abstract: Background: Multiple modes of cell death occur during the development of sepsis. Among these patterns, cuproptosis has recently been identified as a regulated form of cell death. However, its impact on the onset and progression of sepsis remains unclear. ...

    Abstract Background: Multiple modes of cell death occur during the development of sepsis. Among these patterns, cuproptosis has recently been identified as a regulated form of cell death. However, its impact on the onset and progression of sepsis remains unclear. Method: We screened a dataset of gene expression profiles from patients with sepsis using the GEO database. Survival analysis was performed to analyze the relationship between cuproptosis-related genes (CRGs) and prognosis. Hub genes were identified through univariate Cox regression analysis. The diagnostic value of hub genes in sepsis was tested in both training sets (GSE65682) and validation sets (GSE134347). To examine the association between hub genes and immune cells, single-sample gene set enrichment analysis (ssGSEA) and Pearson correlation analysis were employed. Additionally, the CRGs were validated in a septic mouse model using real-time quantitative PCR (qRT-PCR) and immunohistochemistry (IHC). Results: In sepsis, most CRGs were upregulated, with only DLD and MTF1 downregulated. High expression of three genes (GLE, LIAS, and PDHB) was associated with better prognosis, but only two hub genes (LIAS, PDHB) reached statistical significance. The receiver operating characteristic (ROC) analysis for diagnosing sepsis showed LIAS had a range of 0.793–0.906, while PDHB achieved values of 0.882 and 0.975 in the training and validation sets, respectively. ssGSEA analysis revealed a lower number of immune cells in the sepsis group, and there was a correlation between immune cell population and CRGs (LIAS, PDHB). Analysis in the septic mouse model demonstrated no significant difference in mRNA expression levels and IHC staining between LIAS and PDHB in heart and liver tissues, but up-regulation was observed in lung tissues. Furthermore, the mRNA expression levels and IHC staining of LIAS and PDHB were down-regulated in renal tissues. Conclusions: Cuproptosis is emerging as a significant factor in the development of sepsis. LIAS and PDHB, identified as potential ...
    Keywords Sepsis ; ssGSEA ; GEO ; Immune ; Cuproptosis ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 616
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Linking public leadership and public project success

    Naqib Ullah Khan / Peng Zhongyi / Heesup Han / Antonio Ariza-Montes

    Humanities & Social Sciences Communications, Vol 10, Iss 1, Pp 1-

    the mediating role of team building

    2023  Volume 10

    Abstract: Abstract The existing research has linked the mainstream leadership styles to project success and team building. However, there is a lack of research evidence on how public sector-specific leadership styles influence project success and team building. ... ...

    Abstract Abstract The existing research has linked the mainstream leadership styles to project success and team building. However, there is a lack of research evidence on how public sector-specific leadership styles influence project success and team building. This research uses social information processing theory to explore the influence of public leadership on project success and team building. The study also explores the fundamental processes by which public leadership engenders project success via the mediating mechanism of team building. Analysis of 436 responses from both public sector projects managers-subordinates dyad showed that public leadership positively relates to project success and team building. The analysis also showed that team building positively influences project success. Moreover, the findings revealed that team building partially mediates the influence of public leadership on project success.
    Keywords History of scholarship and learning. The humanities ; AZ20-999 ; Social Sciences ; H
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Springer Nature
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: A collaborative diffusion mechanism of multiple atoms during Cu-Ag bimetal surface reconstruction.

    Yan, Xue / Wang, Xiangxiang / Han, Jingli / Du, Xiangjian / Liu, Zhongyi / Yang, Yongpeng

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 15, Page(s) 10405–10416

    Abstract: The reconstruction of bimetals under reaction conditions is critical for precisely controlling the catalytic performance of bimetallic catalysts. The surface diffusion mechanisms of Cu@Ag nanoparticles before and after CO adsorption were studied in this ... ...

    Abstract The reconstruction of bimetals under reaction conditions is critical for precisely controlling the catalytic performance of bimetallic catalysts. The surface diffusion mechanisms of Cu@Ag nanoparticles before and after CO adsorption were studied in this work. The diffusion patterns with the lowest energy barrier were determined by using
    Language English
    Publishing date 2023-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d2cp05591k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Engineering hyperthermophilic pullulanase to efficiently utilize corn starch for production of maltooligosaccharides and glucose.

    Xie, Ting / Zhou, Li / Han, Laichuang / You, Cuiping / Liu, Zhongmei / Cui, Wenjing / Cheng, Zhongyi / Guo, Junling / Zhou, Zhemin

    Food chemistry

    2024  Volume 446, Page(s) 138652

    Abstract: Pullulanase is a starch-debranching enzyme that hydrolyzes side chain of starch, oligosaccharides and pullulan. Nevertheless, the limited activities of pullulanases constrain their practical application. Herein, the hyperthermophilic type II pullulanase ... ...

    Abstract Pullulanase is a starch-debranching enzyme that hydrolyzes side chain of starch, oligosaccharides and pullulan. Nevertheless, the limited activities of pullulanases constrain their practical application. Herein, the hyperthermophilic type II pullulanase from Pyrococcus yayanosii CH1 (Pul
    MeSH term(s) Starch/chemistry ; Glucose ; Zea mays/metabolism ; Glycoside Hydrolases/metabolism ; Oligosaccharides/chemistry ; Archaea ; Substrate Specificity
    Chemical Substances Starch (9005-25-8) ; pullulanase (EC 3.2.1.41) ; maltooligosaccharides ; Glucose (IY9XDZ35W2) ; Glycoside Hydrolases (EC 3.2.1.-) ; Oligosaccharides
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2024.138652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 3634: Show issues

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  8. Article: Si-Wu Water Extracts Protect against Colonic Mucus Barrier Damage by Regulating Muc2 Mucin Expression in Mice Fed a High-Fat Diet.

    Ruan, Zheng / Yu, Yujuan / Han, Peiheng / Zhang, Li / Hu, Zhongyi

    Foods (Basel, Switzerland)

    2022  Volume 11, Issue 16

    Abstract: A high-fat diet (HFD) could cause gut barrier damage. The herbs in si-wu (SW) include dang gui ( ...

    Abstract A high-fat diet (HFD) could cause gut barrier damage. The herbs in si-wu (SW) include dang gui (
    Language English
    Publishing date 2022-08-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods11162499
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  9. Article ; Online: NMN Alleviates NP-Induced Learning and Memory Impairment Through SIRT1 Pathway in PC-12 Cell.

    Li, Zhongyi / Liu, Huan / Han, Wenna / Zhu, Siyu / Liu, Chunhong

    Molecular neurobiology

    2023  Volume 60, Issue 5, Page(s) 2871–2883

    Abstract: Nonylphenol (NP) is widely used in the chemical industry; it accumulates in organisms through environmental contamination and causes learning memory impairment. Nicotinamide mononucleotide (NMN) has been found to have a positive effect on the treatment ... ...

    Abstract Nonylphenol (NP) is widely used in the chemical industry; it accumulates in organisms through environmental contamination and causes learning memory impairment. Nicotinamide mononucleotide (NMN) has been found to have a positive effect on the treatment of central nervous-related diseases. This study aimed to investigate the protective effect of NMN on NP-induced learning memory-related impairment in vitro and to further identify the underlying mechanisms. The results showed that NP induced oxidative stress and impaired the cholinergic system, 5-HT system in PC-12 cells. NMN alleviated NP-induced learning and memory impairment at the molecular level through alleviating oxidative stress and protective effects on the 5-HT system and cholinergic system. The 50 μM NP group significantly reduced the NAD
    MeSH term(s) Brain-Derived Neurotrophic Factor ; Cholinergic Agents ; NAD/metabolism ; Nicotinamide Mononucleotide/metabolism ; Nicotinamide Mononucleotide/pharmacology ; Serotonin ; Sirtuin 1/metabolism ; PC12 Cells ; Animals ; Rats
    Chemical Substances Brain-Derived Neurotrophic Factor ; Cholinergic Agents ; NAD (0U46U6E8UK) ; Nicotinamide Mononucleotide (1094-61-7) ; nonylphenol (79F6A2ILP5) ; Serotonin (333DO1RDJY) ; Sirtuin 1 (EC 3.5.1.-)
    Language English
    Publishing date 2023-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645020-9
    ISSN 1559-1182 ; 0893-7648
    ISSN (online) 1559-1182
    ISSN 0893-7648
    DOI 10.1007/s12035-023-03251-9
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2411: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Learning Transferable Parameters for Unsupervised Domain Adaptation.

    Han, Zhongyi / Sun, Haoliang / Yin, Yilong

    IEEE transactions on image processing : a publication of the IEEE Signal Processing Society

    2022  Volume 31, Page(s) 6424–6439

    Abstract: Unsupervised domain adaptation (UDA) enables a learning machine to adapt from a labeled source domain to an unlabeled target domain under the distribution shift. Thanks to the strong representation ability of deep neural networks, recent remarkable ... ...

    Abstract Unsupervised domain adaptation (UDA) enables a learning machine to adapt from a labeled source domain to an unlabeled target domain under the distribution shift. Thanks to the strong representation ability of deep neural networks, recent remarkable achievements in UDA resort to learning domain-invariant features. Intuitively, the goal is that a good feature representation and the hypothesis learned from the source domain can generalize well to the target domain. However, the learning processes of domain-invariant features and source hypotheses inevitably involve domain-specific information that would degrade the generalizability of UDA models on the target domain. The lottery ticket hypothesis proves that only partial parameters are essential for generalization. Motivated by it, we find in this paper that only partial parameters are essential for learning domain-invariant information. Such parameters are termed transferable parameters that can generalize well in UDA. In contrast, the rest parameters tend to fit domain-specific details and often cause the failure of generalization, which are termed untransferable parameters. Driven by this insight, we propose Transferable Parameter Learning (TransPar) to reduce the side effect of domain-specific information in the learning process and thus enhance the memorization of domain-invariant information. Specifically, according to the distribution discrepancy degree, we divide all parameters into transferable and untransferable ones in each training iteration. We then perform separate update rules for the two types of parameters. Extensive experiments on image classification and regression tasks (keypoint detection) show that TransPar outperforms prior arts by non-trivial margins. Moreover, experiments demonstrate that TransPar can be integrated into the most popular deep UDA networks and be easily extended to handle any data distribution shift scenarios.
    MeSH term(s) Neural Networks, Computer
    Language English
    Publishing date 2022-10-21
    Publishing country United States
    Document type Journal Article
    ISSN 1941-0042
    ISSN (online) 1941-0042
    DOI 10.1109/TIP.2022.3184848
    Database MEDical Literature Analysis and Retrieval System OnLINE

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