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  1. Article ; Online: Comment on "Sensing Technologies for Extravasation Detection: A Review".

    van Rens, Matheus F P T / Spencer, Timothy R

    ACS sensors

    2023  Volume 8, Issue 8, Page(s) 3272–3273

    Language English
    Publishing date 2023-07-27
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2379-3694
    ISSN (online) 2379-3694
    DOI 10.1021/acssensors.3c00838
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  2. Article: Disorder and Sorption Preferences in a Highly Stable Fluoride-Containing Rare-Earth

    Lutton-Gething, A R Bonity J / Spencer, Ben F / Whitehead, George F S / Vitorica-Yrezabal, Iñigo J / Lee, Daniel / Attfield, Martin P

    Chemistry of materials : a publication of the American Chemical Society

    2024  Volume 36, Issue 4, Page(s) 1957–1965

    Abstract: Rare-earth (RE) metal-organic frameworks (MOFs) synthesized in the presence of fluorine-donating modulators or linkers are an important new subset of functional MOFs. However, the exact nature of the ... ...

    Abstract Rare-earth (RE) metal-organic frameworks (MOFs) synthesized in the presence of fluorine-donating modulators or linkers are an important new subset of functional MOFs. However, the exact nature of the RE
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1500399-1
    ISSN 1520-5002 ; 0897-4756
    ISSN (online) 1520-5002
    ISSN 0897-4756
    DOI 10.1021/acs.chemmater.3c02849
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  3. Article: Developmental asynchrony might not reduce fitness in early life in painted turtles.

    Colbert, P L / Spencer, R-J / Janzen, F J

    Frontiers in physiology

    2022  Volume 13, Page(s) 923912

    Abstract: Synchronous hatching and emergence of turtles from nests may be adaptive in predator avoidance during dispersal. However, little is known about the phenotypic consequences of such synchrony or the generality of predator avoidance in driving the evolution ...

    Abstract Synchronous hatching and emergence of turtles from nests may be adaptive in predator avoidance during dispersal. However, little is known about the phenotypic consequences of such synchrony or the generality of predator avoidance in driving the evolution of this trait. Colbert et al. (2010) found that less advanced embryos hatched early in the presence of more advanced sibs, sustaining a persistent reduction in neuromuscular function. In this study, we experimentally assessed the influence of such accelerated embryonic development on hatching success, winter survival, and survival during terrestrial dispersal from the nest. Although we predicted that shortened incubation periods would reduce survival, early-hatching individuals suffered no detectable fitness costs at any stage considered in this study. Incubation temperature did not affect hatching success, and offspring sex did not affect survival across treatment groups. Incubation regime influenced offspring body size and was negatively correlated with dispersal time, however, there was no effect on survival during winter or terrestrial dispersal. Lack of a detectable fitness cost in these key early-life stages associated with hatching synchrony is consistent with a single, predator avoidance origin for this trait and retention in
    Language English
    Publishing date 2022-08-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2022.923912
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  4. Article ; Online: Alcohol-induced Death Rates in the United States, 2019-2020.

    Spencer, Merianne R / Curtin, Sally C / Garnett, Matthew F

    NCHS data brief

    2022  , Issue 448, Page(s) 1–8

    Abstract: Alcohol use is a known risk factor for mortality, and the rates of alcohol induced deaths have risen over the past several years (1). Alcohol use in the United States increased during the first year of the Coronavirus Disease 2019 (COVID-19) pandemic, ... ...

    Abstract Alcohol use is a known risk factor for mortality, and the rates of alcohol induced deaths have risen over the past several years (1). Alcohol use in the United States increased during the first year of the Coronavirus Disease 2019 (COVID-19) pandemic, which may have affected mortality rates, especially for alcohol-induced deaths (2). Understanding trends in alcohol-induced mortality, with a particular focus on differences from 2019 to 2020, may help identify groups particularly affected during the COVID-19 pandemic. This report presents overall and sex-specific trends in alcohol-induced death rates from 2000 to 2020, and then focuses on the rates for 2019 and 2020 by sex, age group, and underlying cause of death.
    MeSH term(s) Male ; Female ; United States/epidemiology ; Humans ; Pandemics ; COVID-19 ; Alcohol Drinking/epidemiology ; Risk Factors ; Cause of Death ; Mortality
    Language English
    Publishing date 2022-11-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2506576-2
    ISSN 1941-4927 ; 1941-4935
    ISSN (online) 1941-4927
    ISSN 1941-4935
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  5. Article ; Online: The key role of absolute risk in the disclosure risk assessment of public data releases.

    Hotz, V Joseph / Bollinger, Christopher R / Komarova, Tatiana / Manski, Charles F / Moffitt, Robert A / Nekipelov, Denis / Sojourner, Aaron / Spencer, Bruce D

    Proceedings of the National Academy of Sciences of the United States of America

    2024  Volume 121, Issue 11, Page(s) e2321882121

    MeSH term(s) Disclosure
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Letter
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2321882121
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1148: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  6. Article ; Online: Reply to Hoad et al. Comment on White paper on pandemic preparedness in the blood supply.

    Strengers, Paul / O'Brien, Sheila F / Politis, Constantina / Mayr, Wolfgang / Seifried, Erhard / Spencer, Bryan R

    Vox sanguinis

    2023  Volume 118, Issue 5, Page(s) 411–412

    MeSH term(s) Humans ; Pandemics/prevention & control ; Blood Banking/supply & distribution
    Language English
    Publishing date 2023-03-15
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80313-3
    ISSN 1423-0410 ; 0042-9007
    ISSN (online) 1423-0410
    ISSN 0042-9007
    DOI 10.1111/vox.13424
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 74: Show issues Location:
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  7. Article ; Online: A teenager with adenoviral myocarditis mimicking hypertrophic cardiomyopathy.

    Aydin, Aybike / Ali, Farwa / Khariton, Megan / Spencer, Robert

    Cardiology in the young

    2023  Volume 33, Issue 10, Page(s) 2110–2112

    Abstract: A 14-year-old previously healthy female presented with chest pain and dyspnoea for 2 days in the setting of a recent upper respiratory infection. She had elevated inflammatory markers and troponin, resulting in the diagnosis of acute myocarditis. ... ...

    Abstract A 14-year-old previously healthy female presented with chest pain and dyspnoea for 2 days in the setting of a recent upper respiratory infection. She had elevated inflammatory markers and troponin, resulting in the diagnosis of acute myocarditis. Transthoracic echocardiography demonstrated mild systolic dysfunction and a moderate pericardial effusion. Additionally, her echocardiogram showed concentric left ventricular hypertrophy raising concern for hypertrophic cardiomyopathy. She was treated with intravenous immunoglobulin. Serial echocardiograms revealed rapid resolution of her ventricular hypertrophy. Cardiac magnetic resonance confirmed the diagnosis of myocarditis.
    MeSH term(s) Female ; Adolescent ; Humans ; Myocarditis/diagnosis ; Cardiomyopathy, Hypertrophic/diagnosis ; Hypertrophy, Left Ventricular/diagnosis ; Heart ; Echocardiography
    Language English
    Publishing date 2023-04-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1078466-4
    ISSN 1467-1107 ; 1047-9511
    ISSN (online) 1467-1107
    ISSN 1047-9511
    DOI 10.1017/S1047951123000975
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    Zs.A 4050: Show issues Location:
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  8. Article ; Online: Active-illumination extension to the Priest and Meier pBRDF.

    Spencer, Mark F / Hyde, Milo W / Bose-Pillai, Santasri R / Marciniak, Michael A

    Optics express

    2023  Volume 31, Issue 22, Page(s) 37105–37127

    Abstract: This paper develops a 3D vector solution for the scattering of partially coherent laser-beam illumination from statistically rough surfaces. Such a solution enables a rigorous comparison to the well-known Priest and Meier polarimetric bidirectional ... ...

    Abstract This paper develops a 3D vector solution for the scattering of partially coherent laser-beam illumination from statistically rough surfaces. Such a solution enables a rigorous comparison to the well-known Priest and Meier polarimetric bidirectional reflectance distribution function (pBRDF) [Opt. Eng.41(5), 988 (2002)10.1117/1.1467360]. Overall, the comparison shows excellent agreement for the normalized spectral density and the degree of polarization. Based on this agreement, the 3D vector solution also enables an extension to the Priest and Meier pBRDF that accounts for the effects of active illumination. In particular, the 3D vector solution enables the development of a closed-form expression for the spectral degree of coherence. This expression provides a gauge for the average speckle size based on the spatial-coherence properties of the laser source. Such an extension is of broad interest to long-range applications that deal with speckle phenomena.
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.503048
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  9. Article ; Online: A high-density 3-dimensional culture model of human glioblastoma for rapid screening of therapeutic resistance.

    Brown, J M C / Zaben, M / Ormonde, C / Sharouf, F / Spencer, R / Bhatt, H / Siebzehnrubl, F A / Gray, W P

    Biochemical pharmacology

    2023  Volume 208, Page(s) 115410

    Abstract: Glioblastoma is among the most lethal cancers, with no known cure. A multitude of therapeutics are being developed or in clinical trials, but currently there are no ways to predict which patient may benefit the most from which drug. Assays that allow ... ...

    Abstract Glioblastoma is among the most lethal cancers, with no known cure. A multitude of therapeutics are being developed or in clinical trials, but currently there are no ways to predict which patient may benefit the most from which drug. Assays that allow prediction of the tumor's response to anti-cancer drugs may improve clinical decision-making. Here, we present a high-density 3D primary cell culture model for short-term testing from resected glioblastoma tissue that is set up on the day of surgery, established within 7 days and viable for at least 3 weeks. High-density 3D cultures contain tumor and host cells, including microglia, and retain key histopathological characteristics of their parent tumors, including proliferative activity, expression of the marker GFAP, and presence of giant cells. This provides a proof-of-concept that 3D primary cultures may be useful to model tumor heterogeneity. Importantly, we show that high-density 3D cultures can be used to test chemotherapy response within a 2-3-week timeframe and are predictive of patient response to Temozolomide therapy. Thus, primary high-density 3D cultures could be a useful tool for brain cancer research and prediction of therapeutic resistance.
    MeSH term(s) Humans ; Glioblastoma/metabolism ; Drug Resistance, Neoplasm ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Temozolomide/pharmacology ; Temozolomide/therapeutic use ; Brain Neoplasms/drug therapy ; Brain Neoplasms/pathology ; Cell Line, Tumor
    Chemical Substances Antineoplastic Agents ; Temozolomide (YF1K15M17Y)
    Language English
    Publishing date 2023-01-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208787-x
    ISSN 1873-2968 ; 0006-2952
    ISSN (online) 1873-2968
    ISSN 0006-2952
    DOI 10.1016/j.bcp.2023.115410
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    Zs.A 19: Show issues Location:
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  10. Article ; Online: On the Initialization of Swarm Intelligence Algorithms for Vector Quantization Codebook Design.

    Severo, Verusca / Ferreira, Felipe B S / Spencer, Rodrigo / Nascimento, Arthur / Madeiro, Francisco

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 8

    Abstract: Vector Quantization (VQ) is a technique with a wide range of applications. For example, it can be used for image compression. The codebook design for VQ has great significance in the quality of the quantized signals and can benefit from the use of swarm ... ...

    Abstract Vector Quantization (VQ) is a technique with a wide range of applications. For example, it can be used for image compression. The codebook design for VQ has great significance in the quality of the quantized signals and can benefit from the use of swarm intelligence. Initialization of the Linde-Buzo-Gray (LBG) algorithm, which is the most popular VQ codebook design algorithm, is a step that directly influences VQ performance, as the convergence speed and codebook quality depend on the initial codebook. A widely used initialization alternative is random initialization, in which the initial set of codevectors is drawn randomly from the training set. Other initialization methods can lead to a better quality of the designed codebooks. The present work evaluates the impacts of initialization strategies on swarm intelligence algorithms for codebook design in terms of the quality of the designed codebooks, assessed by the quality of the reconstructed images, and in terms of the convergence speed, evaluated by the number of iterations. Initialization strategies consist of a combination of codebooks obtained by initialization algorithms from the literature with codebooks composed of vectors randomly selected from the training set. The possibility of combining different initialization techniques provides new perspectives in the search for the quality of the VQ codebooks. Nine initialization strategies are presented, which are compared with random initialization. Initialization strategies are evaluated on the following algorithms for codebook design based on swarm clustering: modified firefly algorithm-Linde-Buzo-Gray (M-FA-LBG), modified particle swarm optimization-Linde-Buzo-Gray (M-PSO-LBG), modified fish school search-Linde-Buzo-Gray (M-FSS-LBG) and their accelerated versions (M-FA-LBGa, M-PSO-LBGa and M-FSS-LBGa) which are obtained by replacing the LBG with the accelerated LBG algorithm. The simulation results point out to the benefits of the proposed initialization strategies. The results show gains up to 4.43 dB in terms of PSNR for image Clock with M-PSO-LBG codebooks of size 512 and codebook design time savings up to 67.05% for image Clock, with M-FF-LBGa codebooks with size N=512, by using initialization strategies in substitution to Random initialization.
    Language English
    Publishing date 2024-04-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24082606
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