Article ; Online: Feasibility of the J-PET to monitor the range of therapeutic proton beams.
2024 Volume 118, Page(s) 103301
Abstract: ... Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring.: Methods: The Monte Carlo ... J-PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil ... geometries for the J-PET scanner prototype dedicated to the proton beam range assessment.: Results ...
Abstract | Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J-PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread-Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J-PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double-layer cylindrical and triple-layer double-head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10 |
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MeSH term(s) | Protons ; Feasibility Studies ; Positron-Emission Tomography ; Proton Therapy/methods ; Phantoms, Imaging ; Monte Carlo Method |
Chemical Substances | Protons |
Language | English |
Publishing date | 2024-01-29 |
Publishing country | Italy |
Document type | Journal Article |
ZDB-ID | 1122650-x |
ISSN | 1724-191X ; 1120-1797 |
ISSN (online) | 1724-191X |
ISSN | 1120-1797 |
DOI | 10.1016/j.ejmp.2024.103301 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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