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Article ; Online: Bay

Rivas, Carlos J / Mena, Leandro D / Baumgartner, María T / Jimenez, Liliana B

2024 Volume 89, Issue 4, Page(s) 2764–2770

Abstract: In this study, we delve into the regioselectivity of nucleophilic reactions involving brominated perylene bisimides (PBIs) and various bidentate aryloxide anions, previously associated with an ... ...

Abstract	In this study, we delve into the regioselectivity of nucleophilic reactions involving brominated perylene bisimides (PBIs) and various bidentate aryloxide anions, previously associated with an S
Language	English
Publishing date	2024-01-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	123490-0
ISSN	1520-6904 ; 0022-3263
ISSN (online)	1520-6904
ISSN	0022-3263
DOI	10.1021/acs.joc.3c02002
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Article ; Online: Odontology and Artificial Intelligence

Lisneybi González González / Junior Vega Jiménez / Leandro L. Lorente Leyva

Revista Cubana de Medicina Militar, Vol 52, Iss 4, Pp e023018125-e

2023 Volume 023018125

Abstract: Odontology and Artificial ... ...

Abstract	Odontology and Artificial Intelligence
Keywords	odontología ; inteligencia artificial ; tecnología odontológica ; Medicine ; R ; Medicine (General) ; R5-920
Language	Spanish
Publishing date	2023-10-01T00:00:00Z
Publisher	ECIMED
Document type	Article ; Online
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Article ; Online: The effect of chronic high-intensity interval training programs on glycaemic control, aerobic resistance, and body composition in type 2 diabetic patients: a meta-analysis.

Arrieta-Leandro, M C / Moncada-Jiménez, J / Morales-Scholz, M G / Hernández-Elizondo, J

Journal of endocrinological investigation

2023 Volume 46, Issue 12, Page(s) 2423–2443

Abstract: Background: Type 2 diabetes is an increasing health problem worldwide. HIIT has been proposed as an exercise alternative to be part of integral type 2 diabetes treatment.: Objective: The aim of this meta-analysis was to determine the effect of ... ...

Abstract	Background: Type 2 diabetes is an increasing health problem worldwide. HIIT has been proposed as an exercise alternative to be part of integral type 2 diabetes treatment. Objective: The aim of this meta-analysis was to determine the effect of different types of chronic HIIT on glycaemic control, aerobic resistance, and body composition in individuals above 18 years with T2D. Design: This meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement and was registered with PROSPERO on November 21st, 2021. Data sources: A systematic literature search of the following databases: EbscoHost (Academic Search Ultimate, Fuente Académica Plus, MEDline and SportDiscus), Web of Science, PubMed, and EMBASE between April of 2021 and April of 2023 was conducted. Eligibility criteria for selecting studies: Eligibility criteria included (1) participants aged ≥ 18 years with a diagnosis of type 2 diabetes, (2) an HIIT protocol with detailed description, (3) control group and/or continuous aerobic training comparison group, (4) report of pre-test and post-test values for at least one of the studied variables (from glycaemic control, aerobic resistance, and/or body composition), and (5) experimental or quasi-experimental intervention design. Analyses: Meta-analysis was made by a pre-post-test between-group analysis following the inverse variance heterogeneity model for each variable, and then, a subgroup analysis by type of HIIT was conducted. Results: Of the 2817 records obtained, 180 records were included for meta-analysis. Significant improvements were found in the most part of the variables when HIIT was compared to control group, while fat-free mass kept without changes. HIIT vs. continuous aerobic training results showed and advantage in favor of HIIT for fasting blood glycemia. Subgroup analysis refers a possible advantage of SI-HIIT and SIT-HIIT in the improvement of fasting glycemia and SIT-HIIT advantage in HOMA 1-IR decrease. Conclusions: HIIT improves glycaemic control, aerobic resistance, and % fat and waist circumference, and kept fat-free mass unchanged in individuals with T2D. SI-HIIT and SIT-HIIT could be better than the other types of HIIT. HIIT benefit is similar to continuous aerobic training except for fasting blood glycemia.
MeSH term(s)	Humans ; High-Intensity Interval Training/methods ; Diabetes Mellitus, Type 2/therapy ; Glycemic Control ; Body Composition ; Exercise
Language	English
Publishing date	2023-07-15
Publishing country	Italy
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	432272-1
ISSN	1720-8386 ; 0391-4097 ; 1121-1369
ISSN (online)	1720-8386
ISSN	0391-4097 ; 1121-1369
DOI	10.1007/s40618-023-02144-x
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Article ; Online: Evolutionary analysis identifies a Golgi pathway and correlates lineage-specific factors with endomembrane organelle emergence in apicomplexans.

Klinger, Christen M / Jimenez-Ruiz, Elena / Mourier, Tobias / Klingl, Andreas / Lemgruber, Leandro / Pain, Arnab / Dacks, Joel B / Meissner, Markus

Cell reports

2024 Volume 43, Issue 2, Page(s) 113740

Abstract: The organelle paralogy hypothesis (OPH) aims to explain the evolution of non-endosymbiotically derived organelles. It predicts that lineage-specific pathways or organelles should result when identity-encoding membrane-trafficking components duplicate and ...

Abstract	The organelle paralogy hypothesis (OPH) aims to explain the evolution of non-endosymbiotically derived organelles. It predicts that lineage-specific pathways or organelles should result when identity-encoding membrane-trafficking components duplicate and co-evolve. Here, we investigate the presence of such lineage-specific membrane-trafficking machinery paralogs in Apicomplexa, a globally important parasitic lineage. We are able to identify 18 paralogs of known membrane-trafficking machinery, in several cases co-incident with the presence of new endomembrane organelles in apicomplexans or their parent lineage, the Alveolata. Moreover, focused analysis of the apicomplexan Arf-like small GTPases (i.e., ArlX3) revealed a specific post-Golgi trafficking pathway. This pathway appears involved in delivery of proteins to micronemes and rhoptries, with knockdown demonstrating reduced invasion capacity. Overall, our data have identified an unforeseen post-Golgi trafficking pathway in apicomplexans and are consistent with the OPH mechanism acting to produce endomembrane pathways or organelles at various evolutionary stages across the alveolate lineage.
MeSH term(s)	Golgi Apparatus ; Apicomplexa
Language	English
Publishing date	2024-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2649101-1
ISSN	2211-1247 ; 2211-1247
ISSN (online)	2211-1247
ISSN	2211-1247
DOI	10.1016/j.celrep.2024.113740
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Article ; Online: Assessing and Understanding Arsenic Contamination in Agricultural Soils and Lake Sediments from Papallacta Rural Parish, Northeastern Ecuador, via Ecotoxicology Factors, for Environmental Embasement

Paul Andres Jimenez Jimenez / Ximena Díaz / Marx Leandro Naves Silva / Anyela Vega / Nilton Curi

Sustainability, Vol 15, Iss 3951, p

2023 Volume 3951

Abstract: The concentration of arsenic (As), considered a toxic and carcinogenic metalloid, in agricultural soils has become a global challenge. Sources of arsenic in soils can be both anthropogenic and natural. Contaminated water is used for the irrigation of ... ...

Abstract	The concentration of arsenic (As), considered a toxic and carcinogenic metalloid, in agricultural soils has become a global challenge. Sources of arsenic in soils can be both anthropogenic and natural. Contaminated water is used for the irrigation of crops and vegetables, and therefore it is the main pathway for arsenic to enter the human food chain, creating a potential health risk. This study evaluated the concentrations of arsenic in agricultural soils in the rural parish of Papallacta, located 67 km east of the city of Quito, Northeastern Ecuador, and constitutes an analysis of the problem of arsenic in agricultural soils. Shallow groundwater and geothermal water discharges laced with arsenic are frequently used for irrigation and have raised the level of arsenic in agricultural soils. This work is focused on evaluating the environmental quality and contamination of agricultural soils through environmental quality indices such as geo-accumulation index, enrichment, and contamination factor. The average arsenic levels in the agricultural soils of the four studied areas fluctuate between 20.4 and 43.0 mg kg −1 , while in the sediments of the Papallacta Lake, higher values were found in the range between 16.8 and 102.4 mg kg −1 all of which exceed the permissible limit by the Ecuadorian Environmental Legislation for agricultural use (12 mg kg −1 ). The results of the study in the five studied sites of the Papallacta civil parish indicate low to moderate levels of arsenic enrichment, soils enriched by bedrock, and moderate to considerable contamination.
Keywords	agricultural soils ; arsenic ; Papallacta ; enrichment factor ; contamination factor ; geo-accumulation ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	333
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Evolutionary and Structural Analysis of PP16 in Viridiplantae.

Jiménez-López, Domingo / Xoconostle-Cázares, Beatriz / Calderón-Pérez, Berenice / Vargas-Hernández, Brenda Yazmín / Núñez-Muñoz, Leandro Alberto / Ramírez-Pool, José Abrahán / Ruiz-Medrano, Roberto

International journal of molecular sciences

2024 Volume 25, Issue 5

Abstract: Members of the phloem protein 16 (PP16) gene family are induced by elicitors in rice and the corresponding proteins from cucurbits, which display RNA binding and intercellular transport activities, are accumulated in phloem sap. These proteins facilitate ...

Abstract	Members of the phloem protein 16 (PP16) gene family are induced by elicitors in rice and the corresponding proteins from cucurbits, which display RNA binding and intercellular transport activities, are accumulated in phloem sap. These proteins facilitate the movement of protein complexes through the phloem translocation flow and may be involved in the response to water deficit, among other functions. However, there is scant information regarding their function in other plants, including the identification of paralog genes in non-vascular plants and chlorophytes. In the present work, an evolutionary and structural analysis of the PP16 family in green plants (Viridiplantae) was carried out. Data mining in different databases indicated that
MeSH term(s)	Plant Proteins/genetics ; Phloem/metabolism ; Plants/metabolism ; Biological Transport ; Viridiplantae/metabolism
Chemical Substances	Plant Proteins
Language	English
Publishing date	2024-02-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25052839
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Article ; Online: Author Correction: The impact of transposable elements on tomato diversity.

Domínguez, Marisol / Dugas, Elise / Benchouaia, Médine / Leduque, Basile / Jiménez-Gómez, José M / Colot, Vincent / Quadrana, Leandro

Nature communications

2021 Volume 12, Issue 1, Page(s) 3203

Language	English
Publishing date	2021-05-21
Publishing country	England
Document type	Published Erratum
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-021-23578-y
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Article ; Online: Serosurveillance of Trichinella sp. in wild boar and Iberian domestic suids in Mediterranean ecosystems of southwestern Spain.

Buffoni, Leandro / Cano-Terriza, David / Jiménez-Martín, Débora / Jiménez-Ruiz, Saúl / Martínez-Moreno, Álvaro / Martínez-Moreno, Francisco Javier / Zafra, Rafael / Pérez-Caballero, Raúl / Risalde, María Ángeles / Gómez-Guillamón, Félix / García-Bocanegra, Ignacio

Zoonoses and public health

2023 Volume 71, Issue 2, Page(s) 191–199

Abstract: Aims: A cross-sectional study was carried out to assess the seroprevalence and risk factors associated with Trichinella spp. exposure in wild boar and Iberian domestic pigs from Mediterranean ecosystems of southwestern Spain.: Methods and results: ... ...

Abstract	Aims: A cross-sectional study was carried out to assess the seroprevalence and risk factors associated with Trichinella spp. exposure in wild boar and Iberian domestic pigs from Mediterranean ecosystems of southwestern Spain. Methods and results: Serum samples from 1360 wild boar and 439 Iberian domestic pigs were obtained during 2015-2020, from regions where Iberian pigs are raised under extensive conditions, hence sharing habitat with wild boar. Seropositivity was found in 7.4% (100/1360; 95% CI: 6.1-8.9) of the wild boar analysed. In this species, the individual seroprevalence ranged from 3.6% (8/223) (hunting season 2016-2017) to 11.4% (37/326) (2018-2019). A significant higher seropositivity was observed during the hunting season 2018-2019 (p < 0.009: OR = 3.07; 95% CI = 1.32-7.18) and one statistically significant cluster was detected within the studied area, in south central Andalusia [Relative Risk (RR) = 2.9; p = 0.037]. Females showed a significantly higher seroprevalence than males (8.7% vs. 5.8%) (p < 0.001: OR = 1.58; 95% CI = 1.08-2.32). No seropositivity to Trichinella spp. was detected in Iberian domestic pigs (0.0%; 95% CI: 0.0-0.9). Conclusions: Although wild boar play an important role as a reservoir of Trichinella sp. in the Mediterranean ecosystems of southwestern Spain, our results suggest that the wild boar production system does not seem to pose a risk of Trichinella exposure to domestic pigs, despite sharing habitats in these ecosystems.
MeSH term(s)	Male ; Female ; Swine ; Animals ; Spain/epidemiology ; Ecosystem ; Seroepidemiologic Studies ; Cross-Sectional Studies ; Sus scrofa ; Trichinella ; Swine Diseases/epidemiology ; Trichinellosis/epidemiology ; Trichinellosis/veterinary
Language	English
Publishing date	2023-11-27
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2271118-1
ISSN	1863-2378 ; 1863-1959
ISSN (online)	1863-2378
ISSN	1863-1959
DOI	10.1111/zph.13098
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Article ; Online: Neuroendoscopic access to the third ventricle in patients with narrow foramen of monro without stenosis/obstruction: role of foraminoplasty.

Guil-Ibáñez, José Javier / Gomar-Alba, Mario / García-Pérez, Fernando / Saucedo, Leandro / Narro-Donate, José María / Vargas-López, Antonio José / Parrón-Carreño, Tesifón / Castro-Luna, Gracia M / Contreras-Jiménez, Ascensión / Masegosa-González, José

Acta neurochirurgica

2024 Volume 166, Issue 1, Page(s) 197

Abstract: Object: One of the critical steps for the success of intraventricular neuroendoscopic procedures is the entry into the third ventricle and passage of the endoscopy system through the foramen of Monro (FM). A diameter larger than that of the instrument ... ...

Abstract	Object: One of the critical steps for the success of intraventricular neuroendoscopic procedures is the entry into the third ventricle and passage of the endoscopy system through the foramen of Monro (FM). A diameter larger than that of the instrument used is considered a prerequisite for safely performing the technique, as damage to this structure can lead to alterations in the fornix and vascular structures. When the foramen diameter is narrow and there is no obstruction/stenosis, the role of foraminoplasty in reducing the risk of complications has not been adequately assessed in the literature. Methods: A review of endoscopic procedures conducted at our center since 2018 was undertaken. Cases in which preoperative imaging indicated a FM diameter < 6 mm and foraminoplasty technique was applied were examined to determine the technical and functional success of the procedure. The technical success was determined by completing the neuroendoscopic procedure with the absence of macroscopic lesions in the various structures comprising the foramen and without complications in the follow-up imaging tests. Functional success was defined as the absence of cognitive/memory alterations during the 3-month postoperative follow-up. Additionally, a review of the various forms of foraminoplasty described in the literature is conducted. Results: In our cohort, six patients were identified with a preoperative FM diameter < 6 mm without obstruction or stenosis. Foraminoplasty was planned for these cases to facilitate various intraventricular neuroendoscopic procedures. In all instances, the technique was successfully performed without causing macroscopic damage to the structures comprising the foramen. Follow-up visits included various cognitive tests to assess potential sequelae related to microscopic damage to the fornix. None of the patients exhibited anomalies. Conclusion: Foraminoplasty in patients with a narrow FM without signs of stenosis/obstruction is a useful technique to reduce the risk of complications during the passage of the endoscopy system through this structure, enabling the safe performance of neuroendoscopic procedures.
MeSH term(s)	Humans ; Neuroendoscopy/methods ; Male ; Female ; Third Ventricle/surgery ; Third Ventricle/diagnostic imaging ; Adult ; Middle Aged ; Hydrocephalus/surgery ; Hydrocephalus/diagnostic imaging ; Adolescent ; Young Adult ; Child ; Retrospective Studies ; Treatment Outcome ; Aged
Language	English
Publishing date	2024-04-29
Publishing country	Austria
Document type	Journal Article
ZDB-ID	80010-7
ISSN	0942-0940 ; 0001-6268
ISSN (online)	0942-0940
ISSN	0001-6268
DOI	10.1007/s00701-024-06077-z
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Article ; Online: Intervención educativa sobre factores de riesgo coronarios en pacientes jóvenes

Jose Leandro Pérez Guerrero / William Arias Salazar / Carmen Paula Rodríguez Jiménez / Dora Esther Paumier Zaldívar

Medimay, Vol 30, Iss 3, Pp 309-

2023 Volume 315

Abstract: Introducción: Las enfermedades cardiovasculares constituyen un problema de salud mundial, cada vez es más frecuente en los jóvenes. Objetivo: Evaluar la efectividad de una intervención educativa, sobre los factores de riesgo coronarios en los pacientes ... ...

Abstract	Introducción: Las enfermedades cardiovasculares constituyen un problema de salud mundial, cada vez es más frecuente en los jóvenes. Objetivo: Evaluar la efectividad de una intervención educativa, sobre los factores de riesgo coronarios en los pacientes jóvenes. Métodos: Se realizó una intervención educativa con un diseño cuasiexperimental, antes y después, sin grupo control, en el consultorio No.10, del Policlínico ¨Alex Urquiola¨, del municipio de Holguín, de enero a abril de 2021. Para la selección de la muestra se utilizó un muestreo no probabilístico, intencional por criterio, quedó conformada por 140 pacientes. Las variables estudiadas fueron: edad, el sexo; el conocimiento de los factores de riesgo coronarios, la percepción del riesgo y la incidencia de los factores de riesgo modificables. Se realizó un diagnóstico inicial a través de una encuesta y se evaluó su efectividad, en la última etapa de la intervención. Resultados: Predominó el sexo masculino en el 58.15 % y el grupo de edad de 40 a 45 años, el 3.28 %. Posterior a la aplicación, el 100 % de los pacientes conocían los factores de riesgo coronarios. Antes de la estrategia, solo tuvieron una adecuada percepción del riesgo el 14.28 % y luego aumentó al 91.42 %. El 91.42 % de los jóvenes fumaban y luego de aplicada la estrategia educativa, solo el 42.85 % continuaron con el hábito. Conclusiones: Aumenta el nivel de conocimientos, sobre los factores de riego cardiovasculares, se eleva la percepción del riesgo y disminuye su prevalencia, en los pacientes jóvenes.
Keywords	factores de riesgo ; prevención ; enfermedades cardiovasculares ; Medicine ; R ; Medicine (General) ; R5-920
Language	Spanish
Publishing date	2023-09-01T00:00:00Z
Publisher	Centro Provincial de Ciencias Médicas Mayabeque
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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