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  1. Article ; Online: Specificity and sensitivity of an indirect fluorescent antibody test to detect antibodies against bovine viral diarrhea virus.

    Karakida, Naoya / Murakami, Momoko / Takeda, Yohei / Ogawa, Haruko / Imai, Kunitoshi

    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

    2024  Volume 36, Issue 2, Page(s) 222–228

    Abstract: Since being reported in 1979 and 2006, indirect fluorescent antibody (IFA) tests have not been reported to detect bovine viral diarrhea virus (BVDV) antibodies to our knowledge. Thus, we re-evaluated the efficacy and usefulness of IFA tests for BVDV ... ...

    Abstract Since being reported in 1979 and 2006, indirect fluorescent antibody (IFA) tests have not been reported to detect bovine viral diarrhea virus (BVDV) antibodies to our knowledge. Thus, we re-evaluated the efficacy and usefulness of IFA tests for BVDV serology. We tested 4 combinations of 2 antibody conjugates (fluorescein isothiocyanate [FITC]-conjugated rabbit IgG anti-bovine IgG; rabbit IgG F(ab')
    MeSH term(s) Cattle ; Animals ; Rabbits ; Fluorescein-5-isothiocyanate ; Diarrhea Viruses, Bovine Viral/genetics ; Diarrhea Virus 1, Bovine Viral/genetics ; Antibodies, Viral ; Immunoglobulin G ; Diarrhea/veterinary ; Bovine Virus Diarrhea-Mucosal Disease/diagnosis ; Cattle Diseases
    Chemical Substances Fluorescein-5-isothiocyanate (I223NX31W9) ; Antibodies, Viral ; Immunoglobulin G
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 287603-6
    ISSN 1943-4936 ; 1040-6387
    ISSN (online) 1943-4936
    ISSN 1040-6387
    DOI 10.1177/10406387241229724
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Rapid Virucidal Activity of Japanese

    Murata, Toshihiro / Jamsransuren, Dulamjav / Matsuda, Sachiko / Ogawa, Haruko / Takeda, Yohei

    Applied and environmental microbiology

    2023  Volume 89, Issue 6, Page(s) e0023723

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus (IAV), and norovirus are global threats to human health. The application of effective virucidal agents, which contribute to the inactivation of viruses on hands and ... ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus (IAV), and norovirus are global threats to human health. The application of effective virucidal agents, which contribute to the inactivation of viruses on hands and environmental surfaces, is important to facilitate robust virus infection control measures. Naturally derived virucidal disinfectants have attracted attention owing to their safety and eco-friendly properties. In this study, we showed that multiple Japanese
    MeSH term(s) Disinfectants/pharmacology ; Influenza A virus/drug effects ; Norovirus/drug effects ; Proanthocyanidins/pharmacology ; SARS-CoV-2/drug effects ; Saxifragaceae/chemistry ; Tannins
    Chemical Substances Disinfectants ; Proanthocyanidins ; Tannins
    Language English
    Publishing date 2023-05-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 223011-2
    ISSN 1098-5336 ; 0099-2240
    ISSN (online) 1098-5336
    ISSN 0099-2240
    DOI 10.1128/aem.00237-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: An

    Maaroufi, Imane / Jamsransuren, Dulamjav / Hashida, Koh / Matsuda, Sachiko / Ogawa, Haruko / Takeda, Yohei

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 9

    Abstract: Researching the beneficial health properties of wood byproducts can prevent wastage by turning them into valuable resources. In this study, the virucidal activity of two extracts ... ...

    Abstract Researching the beneficial health properties of wood byproducts can prevent wastage by turning them into valuable resources. In this study, the virucidal activity of two extracts from
    Language English
    Publishing date 2023-08-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12091093
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  4. Article ; Online: Current status of molecular diagnostic approaches using liquid biopsy.

    Takahashi, Kenji / Takeda, Yohei / Ono, Yusuke / Isomoto, Hajime / Mizukami, Yusuke

    Journal of gastroenterology

    2023  Volume 58, Issue 9, Page(s) 834–847

    Abstract: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal cancers, and developing an efficient and reliable approach for its early-stage diagnosis is urgently needed. Precancerous lesions of PDAC, such as pancreatic intraepithelial ...

    Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal cancers, and developing an efficient and reliable approach for its early-stage diagnosis is urgently needed. Precancerous lesions of PDAC, such as pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasms (IPMN), arise through multiple steps of driver gene alterations in KRAS, TP53, CDKN2A, SMAD4, or GNAS. Hallmark mutations play a role in tumor initiation and progression, and their detection in bodily fluids is crucial for diagnosis. Recently, liquid biopsy has gained attention as an approach to complement pathological diagnosis, and in addition to mutation signatures in cell-free DNA, cell-free RNA, and extracellular vesicles have been investigated as potential diagnostic and prognostic markers. Integrating such molecular information to revise the diagnostic criteria for pancreatic cancer can enable a better understanding of the pathogenesis underlying inter-patient heterogeneity, such as sensitivity to chemotherapy and disease outcomes. This review discusses the current diagnostic approaches and clinical applications of genetic analysis in pancreatic cancer and diagnostic attempts by liquid biopsy and molecular analyses using pancreatic juice, duodenal fluid, and blood samples. Emerging knowledge in the rapidly advancing liquid biopsy field is promising for molecular profiling and diagnosing pancreatic diseases with significant diversity.
    MeSH term(s) Humans ; Pathology, Molecular ; Early Detection of Cancer ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/pathology ; Carcinoma, Pancreatic Ductal/diagnosis ; Carcinoma, Pancreatic Ductal/genetics ; Carcinoma, Pancreatic Ductal/pathology ; Mutation ; Liquid Biopsy ; Pancreatic Neoplasms
    Language English
    Publishing date 2023-07-20
    Publishing country Japan
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1186495-3
    ISSN 1435-5922 ; 0944-1174
    ISSN (online) 1435-5922
    ISSN 0944-1174
    DOI 10.1007/s00535-023-02024-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Conformational features and ionization states of Lys side chains in a protein studied using the stereo-array isotope labeling (SAIL) method.

    Takeda, Mitsuhiro / Miyanoiri, Yohei / Terauchi, Tsutomu / Kainosho, Masatsune

    Magnetic resonance (Gottingen, Germany)

    2021  Volume 2, Issue 1, Page(s) 223–237

    Abstract: Although both ... ...

    Abstract Although both the
    Language English
    Publishing date 2021-04-26
    Publishing country Germany
    Document type Journal Article
    ISSN 2699-0016
    ISSN (online) 2699-0016
    DOI 10.5194/mr-2-223-2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Outbreak of

    Hayama, Brian / Harada, Sohei / Suzuki, Masahiro / Doi, Yohei / Nomura, Yusuke / Aoki, Kotaro / Takehana, Kazumi / Akatsuchi, Tomomi / Enokida, Taisuke / Takeda, Koichi / Seto, Akira / Mitani, Hiroki / Ohkushi, Daisuke

    Microbiology spectrum

    2024  , Page(s) e0426023

    Abstract: Streptococcus pyogenes: Importance: This study describes an outbreak ... ...

    Abstract Streptococcus pyogenes
    Importance: This study describes an outbreak of
    Language English
    Publishing date 2024-04-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.04260-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Correction: Current status and future perspective of linked color imaging for gastric cancer screening: a literature review.

    Yashima, Kazuo / Onoyama, Takumi / Kurumi, Hiroki / Takeda, Yohei / Yoshida, Akira / Kawaguchi, Koichiro / Yamaguchi, Naoyuki / Isomoto, Hajime

    Journal of gastroenterology

    2023  Volume 58, Issue 5, Page(s) 514

    Language English
    Publishing date 2023-03-08
    Publishing country Japan
    Document type Published Erratum
    ZDB-ID 1186495-3
    ISSN 1435-5922 ; 0944-1174
    ISSN (online) 1435-5922
    ISSN 0944-1174
    DOI 10.1007/s00535-023-01971-2
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  8. Article ; Online: Validation study of the modified HEART and HEAR scores in patients with chest pain who visit the emergency department.

    Otsuka, Yohei / Takeda, Satoshi

    Acute medicine & surgery

    2020  Volume 7, Issue 1, Page(s) e591

    Abstract: Aim: To validate the efficacy of the history, electrocardiogram, age, risk factors, and troponin (HEART) and history, electrocardiogram, age, and risk factors (HEAR) scores in a Japanese cohort.: Methods: We used the data of patients who visited our ... ...

    Abstract Aim: To validate the efficacy of the history, electrocardiogram, age, risk factors, and troponin (HEART) and history, electrocardiogram, age, and risk factors (HEAR) scores in a Japanese cohort.
    Methods: We used the data of patients who visited our emergency department between 1 December, 2015 and 31 May, 2017. Patients aged ≥20 years who presented with non-traumatic and undifferentiated chest pain were eligible for the study. On the basis of the total score, the patients were stratified as low risk (HEART and HEAR scores of 0-3), intermediate risk (HEART and HEAR scores of 4-6), and high risk (HEART score of 7-10 and HEAR score of 7-8). The major adverse cardiac events (MACEs) that occurred within 6 weeks were investigated, and the diagnostic value and efficiency of both scores were analyzed.
    Results: In total, 132 patients were included in the HEART score analysis and 220 patients in the HEAR score analysis. The incidence rates of MACEs in patients with low, intermediate, and high risks were 0%, 23.2%, and 63.6% in the HEART score analysis and 4.7%, 22.9%, and 62.5% in the HEAR score analysis (
    Conclusion: The modified HEART and HEAR scores were effective in identifying patients with chest pain who are at low risk of MACEs at an emergency department in Japan.
    Language English
    Publishing date 2020-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2751184-4
    ISSN 2052-8817 ; 2052-8817
    ISSN (online) 2052-8817
    ISSN 2052-8817
    DOI 10.1002/ams2.591
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Partial Stent-in-Stent Method with an Uncovered Self-Expandable Metallic Stent for Unresectable Malignant Hilar Bile Duct Obstruction.

    Shimosaka, Takuya / Takeda, Yohei / Yamashita, Taro / Seki, Yuta / Kawahara, Shiho / Hirai, Takayuki / Suto, Noriyuki / Sakamoto, Yuri / Hamamoto, Wataru / Koda, Hiroki / Onoyama, Takumi / Matsumoto, Kazuya / Yashima, Kazuo / Isomoto, Hajime / Yamaguchi, Naoyuki

    Journal of clinical medicine

    2024  Volume 13, Issue 3

    Abstract: 1) ...

    Abstract (1)
    Language English
    Publishing date 2024-01-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030820
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: In vitro virucidal activity of the theaflavin-concentrated tea extract TY-1 against influenza A virus.

    Mohamed, Israa M A / Ogawa, Haruko / Takeda, Yohei

    Journal of natural medicines

    2021  Volume 76, Issue 1, Page(s) 152–160

    Abstract: The annual spread of influenza A virus (IAV) infection is a global concern. We examined the IAV-inactivating potential of theaflavin-concentrated tea extract TY-1, which contains abundant polyphenols, including concentrated theaflavins and catechins. TY- ... ...

    Abstract The annual spread of influenza A virus (IAV) infection is a global concern. We examined the IAV-inactivating potential of theaflavin-concentrated tea extract TY-1, which contains abundant polyphenols, including concentrated theaflavins and catechins. TY-1 exhibited concentration- and time-dependent virucidal activity against IAV. Specifically, 5.0 mg/mL TY-1 induced a 1.33 and ≥ 5.17 log
    MeSH term(s) Antiviral Agents/pharmacology ; Biflavonoids ; Catechin ; Influenza A virus/drug effects ; Plant Extracts/pharmacology ; Tea/chemistry
    Chemical Substances Antiviral Agents ; Biflavonoids ; Plant Extracts ; Tea ; theaflavin (1IA46M0D13) ; Catechin (8R1V1STN48)
    Language English
    Publishing date 2021-09-22
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2227540-X
    ISSN 1861-0293 ; 1340-3443
    ISSN (online) 1861-0293
    ISSN 1340-3443
    DOI 10.1007/s11418-021-01568-0
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