LIVIVO - Search results -

Search results

Result 1 - 10 of total 177

Search options

Article: Shannon entropy-based fingerprint similarity search strategy.

Wang, Yuan / Geppert, Hanna / Bajorath, Jürgen

Journal of chemical information and modeling

2009 Volume 49, Issue 7, Page(s) 1687–1691

Abstract: For fingerprint searching using multiple active reference compounds, an information entropy-based similarity method is introduced as an alternative to conventional similarity coefficients and search strategies. The approach involves the determination of ... ...

Abstract	For fingerprint searching using multiple active reference compounds, an information entropy-based similarity method is introduced as an alternative to conventional similarity coefficients and search strategies. The approach involves the determination of the fingerprint bit pattern entropy of a compound reference set and recalculation of the entropy following the addition of individual test compounds. If a database compound shares similar bit patterns with reference set molecules, adding this compound to the reference set only produces a small change in system entropy. By contrast, inclusion of a compound having a dissimilar fingerprint leads to a notable increase in entropy. Thus, database compounds can be screened for candidate molecules that do not cause significant changes in reference set fingerprint entropy. Compared to nearest neighbor methods, this approach has the computational advantage that it extracts reference set information only once prior to similarity searching. Test calculations on different compound data sets, fingerprints, and screening databases reveal that the ability of our entropy-based method to detect active compounds is often superior to data fusion techniques and Tanimoto similarity calculations.
MeSH term(s)	Angiotensin-Converting Enzyme Inhibitors/chemistry ; Computational Biology/methods ; Databases, Factual ; Entropy ; Molecular Structure ; Pharmaceutical Preparations/chemistry
Chemical Substances	Angiotensin-Converting Enzyme Inhibitors ; Pharmaceutical Preparations
Language	English
Publishing date	2009-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	190019-5
ISSN	1549-9596 ; 0095-2338
ISSN	1549-9596 ; 0095-2338
DOI	10.1021/ci900159f
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1230: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A Tale of Two Tumors: A Collision Tumor of Atypical Fibroxanthoma and Basal Cell Carcinoma.

Dhaliwal, Dilshad / Sayyadioskoie, Shannon / Siatecka, Hanna / Hunt, Christine / Diwan, A Hafeez

The American Journal of dermatopathology

2024 Volume 46, Issue 5, Page(s) 309–311

Abstract: Abstract: A collision tumor is an infrequent phenomenon characterized by the presence of 2 histologically distinct tumor types (either benign or malignant) occurring within the same specific anatomical site. We describe a rare case of co-occurrence of ... ...

Abstract	Abstract: A collision tumor is an infrequent phenomenon characterized by the presence of 2 histologically distinct tumor types (either benign or malignant) occurring within the same specific anatomical site. We describe a rare case of co-occurrence of basal cell carcinoma and atypical fibroxanthoma presenting as a single lesion on the scalp in a 76-year-old man. The lesion was clinically suspicious for basal cell carcinoma and biopsied. Histologic examination showed 2 distinct tumors, one with basaloid cells and the other one with pleomorphic spindle cells colliding and growing together. Immunohistochemical stains were crucial in establishing the diagnosis. This presentation is exceedingly rare and requires additional evaluation for diagnosis.
MeSH term(s)	Male ; Humans ; Aged ; Histiocytoma, Benign Fibrous/pathology ; Skin Neoplasms/diagnosis ; Carcinoma, Basal Cell/pathology ; Diagnosis, Differential ; Scalp/pathology
Language	English
Publishing date	2024-04-04
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	448469-1
ISSN	1533-0311 ; 0193-1091
ISSN (online)	1533-0311
ISSN	0193-1091
DOI	10.1097/DAD.0000000000002694
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1518: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Reaching consensus on the principles of trauma-informed care in early intervention psychosis services: A Delphi study.

Mitchell, Sinéad / Shannon, Ciaran / Mulholland, Ciaran / Hanna, Donncha

Early intervention in psychiatry

2020 Volume 15, Issue 5, Page(s) 1369–1375

Abstract: Aim: The current study sought to conceptualize and reach consensus on the principles of trauma-informed care in early intervention psychosis services.: Methods: A three-phase Delphi method was employed in this study. Experts included researchers, ... ...

Abstract	Aim: The current study sought to conceptualize and reach consensus on the principles of trauma-informed care in early intervention psychosis services. Methods: A three-phase Delphi method was employed in this study. Experts included researchers, service providers and Experts by Experience in the area of early intervention in psychosis. In the initial qualitative phase, an expert panel (n = 57) shared their views on the constituents of trauma-informed care in early intervention psychosis services. Thematic analysis led to the generation of statement items. The expert panel was asked to rate the extent to which each statement item was an essential principle of trauma-informed care, leading to consensus of endorsed principles. Results: Qualitative analysis of the first phase data led to the identification of 185 distinct statements which were compiled into an online questionnaire for the panel to rate in Phase 2. The Phase 2 questionnaire was completed by 42 experts, with the endorsement of seven principles. In Phase 3, the panel were invited to re-rate 24 statements. This phase was completed by 39 panel members, with the acceptance of a further nine principles. Consensus was achieved resulting in the endorsement of 16 essential principles of trauma-informed care. Conclusions: The study offers novel understanding of the conceptualisation of trauma-informed care in early intervention services and suggests principles which are widely agreed by experts in the field. The recommendations may inform the adoption of consistently delivered trauma-informed care in early interventions in psychosis and facilitate the evaluation and development of services.
MeSH term(s)	Consensus ; Delphi Technique ; Early Intervention, Educational ; Humans ; Psychotic Disorders/diagnosis ; Psychotic Disorders/therapy ; Surveys and Questionnaires
Language	English
Publishing date	2020-11-09
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2272425-4
ISSN	1751-7893 ; 1751-7885
ISSN (online)	1751-7893
ISSN	1751-7885
DOI	10.1111/eip.13068
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article ; Online: The Structure of the Prodromal Questionnaire-16 (PQ-16): Exploratory and confirmatory factor analyses in a general non-help-seeking population sample.

Howie, Clare / Hanna, Donncha / Shannon, Ciaran / Davidson, Gavin / Mulholland, Ciaran

Early intervention in psychiatry

2021 Volume 16, Issue 3, Page(s) 239–246

Abstract: Aims: To examine the structure of the Prodromal Questionnaire (PQ-16) in a non-help-seeking population through exploratory factor analysis and confirmatory factor analysis. Previous studies have not looked at the structure of this self-report measure ... ...

Abstract	Aims: To examine the structure of the Prodromal Questionnaire (PQ-16) in a non-help-seeking population through exploratory factor analysis and confirmatory factor analysis. Previous studies have not looked at the structure of this self-report measure outside clinical settings. Methods: Participants (n = 1045) were recruited through Amazon's Mechanical Turk (MTurk), and then completed the PQ-16. The data set was split randomly in two, one being used for exploratory factor analysis (EFA) and the other for confirmatory factor analysis (CFA). A polychoric correlation matrix was created and EFA was used to explore the factor structure of the PQ-16. Four models were tested through CFA to determine best fit: one, two, three and four-factor models were all analysed. Results: EFA indicated a two-factor structure in the PQ-16 in a non-help-seeking population (with a mean age = 29.7 years). Factor 1 represented perceptual abnormalities/hallucinations and factor 2 general symptoms associated with psychosis-risk. CFA indicated that all the proposed models were suitable fits for the dataset. Fit indices for the three-factor model (factor 1 representing perceptual abnormalities/hallucinations, factor 2 unusual thought content, and factor 3 negative symptom) indicated that it appeared to be a better fit for the data than the one, two, and four factor models. Conclusions: This study suggests that a three-factor model of the PQ-16 is a better fit than other proposed models in a non-help-seeking population. Future research of the structure of the PQ-16 in this population may benefit from recruiting subjects with a lower mean age than the current study.
MeSH term(s)	Adult ; Factor Analysis, Statistical ; Humans ; Prodromal Symptoms ; Psychometrics ; Reproducibility of Results ; Surveys and Questionnaires
Language	English
Publishing date	2021-03-24
Publishing country	Australia
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2272425-4
ISSN	1751-7893 ; 1751-7885
ISSN (online)	1751-7893
ISSN	1751-7885
DOI	10.1111/eip.13147
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article ; Online: Correction to "Fibrin-Dextran Hydrogels with Tunable Porosity and Mechanical Properties".

Jung, Shannon Anna / Malyaran, Hanna / Demco, Dan Eugen / Manukanc, Anna / Häser, Leonie Sophie / Kučikas, Vytautas / van Zandvoort, Marc / Neuss, Sabine / Pich, Andrij

Biomacromolecules

2024 Volume 25, Issue 4, Page(s) 2656–2657

Language	English
Publishing date	2024-03-25
Publishing country	United States
Document type	Published Erratum
ISSN	1526-4602
ISSN (online)	1526-4602
DOI	10.1021/acs.biomac.4c00276
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: The association between sleep quality and attenuated psychotic symptoms.

Clarke, Stephen / Hanna, Donncha / Davidson, Sarah / Shannon, Ciarán / Mulholland, Ciaran

Early intervention in psychiatry

2020 Volume 15, Issue 4, Page(s) 837–848

Abstract: Aim: To determine if poor sleep makes a unique contribution in predicting the likelihood of experiencing six or more attenuated psychotic symptoms and associated distress, after examining and controlling for sociodemographic factors, depression and drug/ ...

Abstract	Aim: To determine if poor sleep makes a unique contribution in predicting the likelihood of experiencing six or more attenuated psychotic symptoms and associated distress, after examining and controlling for sociodemographic factors, depression and drug/alcohol use. Method: An online survey was conducted using Amazon's online crowdsourcing service Mechanical Turk (MTurk). The sample was 1013 adults (18 to 36 years) from the general population in the United States. The survey consisted of the Prodromal Questionnaire 16 (PQ-16), the Pittsburgh Sleep Quality Index, the Patient Health Questionnaire 9, the Drug Abuse Screening Test 10 and the Alcohol Use Disorders Identification Test. Regression analyses were performed with the PQ-16 as the dependent variable, and sleep quality as the predictor variable, holding constant sociodemographic variables, depression, and alcohol/drug abuse. Results: 37% of the sample endorsed six or more PQ-16 items, which may be suggestive of an at-risk mental state, with sleep disturbance significantly increasing the likelihood (Odds ratio 2.09 < .001) of endorsing six or more PQ-16 items. After controlling for sociodemographic variables, depression and drug/alcohol abuse, poor sleep quality made a unique contribution of 5.8% of the variance accounted for in level of distress experienced by attenuated psychotic symptoms. Conclusion: Effective treatment of sleep disturbance may reduce the likelihood ofexperiencing attenuated psychotic symptoms and associated distress.
MeSH term(s)	Adult ; Alcoholism ; Depression ; Humans ; Psychotic Disorders/diagnosis ; Psychotic Disorders/epidemiology ; Sleep ; Sleep Wake Disorders/diagnosis ; Sleep Wake Disorders/epidemiology ; Surveys and Questionnaires ; United States
Language	English
Publishing date	2020-07-16
Publishing country	Australia
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2272425-4
ISSN	1751-7893 ; 1751-7885
ISSN (online)	1751-7893
ISSN	1751-7885
DOI	10.1111/eip.13020
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article ; Online: Habitat detection, habitat choice copying or mating benefits: What drives conspecific attraction in a nomadic songbird?

Luepold, Shannon Buckley / Kokko, Hanna / Grendelmeier, Alex / Pasinelli, Gilberto

Journal of Animal Ecology. 2023 Jan., v. 92, no. 1 p.195-206

2023

Abstract: Conspecific attraction during habitat selection is common among animals, but the ultimate (i.e. fitness‐related) reasons for this behaviour often remain enigmatic. We aimed to evaluate the following three hypotheses for conspecific attraction during the ... ...

Abstract	Conspecific attraction during habitat selection is common among animals, but the ultimate (i.e. fitness‐related) reasons for this behaviour often remain enigmatic. We aimed to evaluate the following three hypotheses for conspecific attraction during the breeding season in male Wood Warblers (Phylloscopus sibilatrix): the habitat detection hypothesis, the habitat choice copying hypothesis and the female preference hypothesis. These hypotheses make different predictions with respect to the relative importance of social and nonsocial information during habitat assessment, and whether benefits accrue as a consequence of aggregation. We tested the above hypotheses using a combination of a 2‐year playback experiment, spatial statistics and mate choice models. The habitat detection hypothesis was the most likely explanation for conspecific attraction and aggregation in male Wood Warblers, based on the following results: (1) males were attracted to conspecific song playbacks, but fine‐scale habitat heterogeneity was the better predictor of spatial patterns in the density of settling males; (2) male pairing success did not increase, but instead slightly decreased, as connectivity with other males (i.e. the number and proximity of neighbouring males) increased. Our study highlights how consideration of the process by which animals detect and assess habitat, together with the potential fitness consequences of resulting aggregations, are important for understanding conspecific attraction and spatially clustered distributions.
Keywords	Phylloscopus sibilatrix ; biological assessment ; conspecificity ; females ; habitat preferences ; habitats ; males ; mating behavior ; songbirds ; statistics ; wood
Language	English
Dates of publication	2023-01
Size	p. 195-206.
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	3024-7
ISSN	1365-2656 ; 0021-8790
ISSN (online)	1365-2656
ISSN	0021-8790
DOI	10.1111/1365-2656.13844
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 72/708: Show issues
Z 2600: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A sex-based analysis of 5-year outcomes following stenting for the treatment of aorto-iliac occlusive disease.

Mwipatayi, Bibombe Patrice / Barry, Ian Patrick / Hanna, Joseph / Macarulay, Reane / Wong, Jackie / Thomas, Shannon / Vijayan, Vikram / Puttaswamy, Vikram / Ward, Natalie C

Vascular

2023 , Page(s) 17085381231194152

Abstract: Objectives: The aim of this study was to evaluate the impact of sex on mid-term outcomes following stenting for aorto-iliac occlusive disease (AIOD).: Methods: The Covered versus Balloon Expandable Stent Trial (COBEST) compared the safety and ... ...

Abstract	Objectives: The aim of this study was to evaluate the impact of sex on mid-term outcomes following stenting for aorto-iliac occlusive disease (AIOD). Methods: The Covered versus Balloon Expandable Stent Trial (COBEST) compared the safety and efficacy of the covered stent (CS) with those of the bare metal stent (BMS) in the treatment of hemodynamically significant AIOD. It was identified that CS provided a significant benefit. The primary endpoint of our analysis was the rate of primary patency 5 years following stenting for AIOD (inclusive of both CS and BMS) in both sexes. Results: Of the 168 lesions treated, 103 (61%) were present in men and 65 (39%) were present in women. Of the concomitant comorbidities, diabetes mellitus was significantly more common in women (17.5% vs 41.5%, Conclusions: No significant difference was identified in the primary patency rate between the sexes. Further investigation is warranted to ascertain whether sex-specific interventional guidelines are required in this regard.
Language	English
Publishing date	2023-08-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2137151-9
ISSN	1708-539X ; 1708-5381
ISSN (online)	1708-539X
ISSN	1708-5381
DOI	10.1177/17085381231194152
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4277: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 590: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Habitat detection, habitat choice copying or mating benefits: What drives conspecific attraction in a nomadic songbird?

Luepold, Shannon Buckley / Kokko, Hanna / Grendelmeier, Alex / Pasinelli, Gilberto

The Journal of animal ecology

2022 Volume 92, Issue 1, Page(s) 195–206

Abstract: Conspecific attraction during habitat selection is common among animals, but the ultimate (i.e. fitness-related) reasons for this behaviour often remain enigmatic. We aimed to evaluate the following three hypotheses for conspecific attraction during the ... ...

Abstract	Conspecific attraction during habitat selection is common among animals, but the ultimate (i.e. fitness-related) reasons for this behaviour often remain enigmatic. We aimed to evaluate the following three hypotheses for conspecific attraction during the breeding season in male Wood Warblers (Phylloscopus sibilatrix): the habitat detection hypothesis, the habitat choice copying hypothesis and the female preference hypothesis. These hypotheses make different predictions with respect to the relative importance of social and nonsocial information during habitat assessment, and whether benefits accrue as a consequence of aggregation. We tested the above hypotheses using a combination of a 2-year playback experiment, spatial statistics and mate choice models. The habitat detection hypothesis was the most likely explanation for conspecific attraction and aggregation in male Wood Warblers, based on the following results: (1) males were attracted to conspecific song playbacks, but fine-scale habitat heterogeneity was the better predictor of spatial patterns in the density of settling males; (2) male pairing success did not increase, but instead slightly decreased, as connectivity with other males (i.e. the number and proximity of neighbouring males) increased. Our study highlights how consideration of the process by which animals detect and assess habitat, together with the potential fitness consequences of resulting aggregations, are important for understanding conspecific attraction and spatially clustered distributions.
MeSH term(s)	Male ; Female ; Animals ; Songbirds ; Ecosystem ; Passeriformes
Language	English
Publishing date	2022-11-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3024-7
ISSN	1365-2656 ; 0021-8790
ISSN (online)	1365-2656
ISSN	0021-8790
DOI	10.1111/1365-2656.13844
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 72/708: Show issues
Z 2600: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Effects of a Mental Health Intervention in Athletes: Applying Self-Determination Theory.

Shannon, Stephen / Hanna, Donncha / Haughey, Tandy / Leavey, Gerard / McGeown, Conor / Breslin, Gavin

Frontiers in psychology

2019 Volume 10, Page(s) 1875

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2019-08-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2019.01875
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito