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  1. Article: Acne vulgaris: one treatment does not fit all.

    Longshore, Sharon J / Hollandsworth, Kimberly

    Cleveland Clinic journal of medicine

    2003  Volume 70, Issue 8, Page(s) 670, 672–4, 677–8 passim

    Abstract: With many treatments now available for acne vulgaris, the treatment must be tailored to the type and severity of the lesions. Most mild-to-moderate cases can be treated with a benzoyl peroxide product, a topical or oral antibiotic, a topical retinoid, or ...

    Abstract With many treatments now available for acne vulgaris, the treatment must be tailored to the type and severity of the lesions. Most mild-to-moderate cases can be treated with a benzoyl peroxide product, a topical or oral antibiotic, a topical retinoid, or a combination of these medications. Antibiotic resistance is becoming a challenge for many once-reliable topical and oral antibiotics.
    MeSH term(s) Acne Vulgaris/drug therapy ; Acne Vulgaris/etiology ; Anti-Bacterial Agents/administration & dosage ; Benzoyl Peroxide/administration & dosage ; Drug Administration Routes ; Drug Combinations ; Drug Therapy, Combination ; Humans ; Retinoids/administration & dosage
    Chemical Substances Anti-Bacterial Agents ; Drug Combinations ; Retinoids ; Benzoyl Peroxide (W9WZN9A0GM)
    Language English
    Publishing date 2003-08-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639116-3
    ISSN 0891-1150
    ISSN 0891-1150
    DOI 10.3949/ccjm.70.8.670
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.212: Show issues Location:
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  2. Article: Malignant acanthosis nigricans and endometrioid adenocarcinoma of the parametrium: the search for malignancy.

    Longshore, Sharon J / Taylor, James S / Kennedy, Alexander / Nurko, Saul

    Journal of the American Academy of Dermatology

    2003  Volume 49, Issue 3, Page(s) 541–543

    Abstract: Malignant acanthosis nigricans is recognized as a cutaneous sign of internal malignancy, usually an adenocarcinoma. Although cases of malignant acanthosis nigricans have been associated with cervical, ovarian, and endometrial neoplasms, we describe a ... ...

    Abstract Malignant acanthosis nigricans is recognized as a cutaneous sign of internal malignancy, usually an adenocarcinoma. Although cases of malignant acanthosis nigricans have been associated with cervical, ovarian, and endometrial neoplasms, we describe a case with a rarely if ever reported association, endometrioid adenocarcinoma of the parametrium.
    MeSH term(s) Acanthosis Nigricans/complications ; Acanthosis Nigricans/pathology ; Adenocarcinoma/etiology ; Adenocarcinoma/pathology ; Adenocarcinoma/therapy ; Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biopsy, Needle ; Carboplatin/administration & dosage ; Chemotherapy, Adjuvant ; Endometrial Neoplasms/etiology ; Endometrial Neoplasms/pathology ; Endometrial Neoplasms/therapy ; Female ; Follow-Up Studies ; Humans ; Hysterectomy/methods ; Immunohistochemistry ; Paclitaxel/administration & dosage ; Risk Assessment ; Treatment Outcome
    Chemical Substances Carboplatin (BG3F62OND5) ; Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2003-08-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1067/s0190-9622(03)00913-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1540: Show issues Location:
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  3. Article ; Online: Childhood dermatofibrosarcoma protuberans: role of preoperative imaging.

    Thornton, Sharon Longshore / Reid, Janet / Papay, Francis A / Vidimos, Allison T

    Journal of the American Academy of Dermatology

    2005  Volume 53, Issue 1, Page(s) 76–83

    Abstract: Dermatofibrosarcoma protuberans (DFSP) is especially challenging to recognize and diagnose in children. Prompt and definitive treatment is essential based on the tumor's high rate of recurrence. Our purpose is to increase physician awareness and ... ...

    Abstract Dermatofibrosarcoma protuberans (DFSP) is especially challenging to recognize and diagnose in children. Prompt and definitive treatment is essential based on the tumor's high rate of recurrence. Our purpose is to increase physician awareness and recognition of DFSP in the pediatric population with the largest case series of childhood DFSP to our knowledge thus reported in the literature. We also propose that magnetic resonance imaging (MRI) may be useful in the preoperative assessment. The records of 10 patients with primary DFSP between the ages of 8 months and 16 years were reviewed. Only 1 of 10 patients was given the correct diagnosis at the initial medical evaluation. Of the 10 cases, 5 were congenital. The average delay in diagnosis was 5 years. Of the patients, 5 had preoperative MRI to delineate the size and extent of the tumor. In the two cases with the largest tumors preoperative MRI significantly altered surgical planning and execution. Thus, preoperative MRI may be helpful in planning for successful surgical clearance of large tumors and preventing local recurrence. All 10 cases were treated with Mohs micrographic surgery and no recurrences were noted with a follow-up range of 6 weeks to 17 years.
    MeSH term(s) Adolescent ; Child, Preschool ; Dermatofibrosarcoma/diagnosis ; Dermatofibrosarcoma/surgery ; Female ; Humans ; Infant ; Magnetic Resonance Imaging ; Male ; Preoperative Care ; Skin Neoplasms/diagnosis ; Skin Neoplasms/surgery
    Language English
    Publishing date 2005-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2004.11.071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1540: Show issues Location:
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  4. Article: Long-term trends in self-reported HIV risk behavior: injection drug users in Los Angeles, 1987 through 1995.

    Longshore, D / Annon, J / Anglin, M D

    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association

    1998  Volume 18, Issue 1, Page(s) 64–72

    Abstract: ... occurred in the percentage who share needles. However, measured over a past-year recall period ... Among IDUs who shared needles, bleach use increased rapidly until 1991 but leveled off thereafter. No change ...

    Abstract This article reviews trends in self-reported HIV risk behaviors across serial samples of injection drug-using (IDU) arrestees interviewed in Los Angeles. Between 1987 and 1995, a gradual decrease occurred in the percentage who share needles. However, measured over a past-year recall period, the prevalence of needle sharing remained high until 1994 to 1995, when it abruptly declined. Needle sharing with strangers and needle sharing at shooting galleries declined gradually throughout the study period. Among IDUs who shared needles, bleach use increased rapidly until 1991 but leveled off thereafter. No change occurred in number of sex partners, but condom use gradually increased among IDUs with 2 or more partners. Concurrent change in local needle exchange policy and practice may explain the abrupt decline in past-year needle sharing. New strategies may be needed to promote further increases in bleach use and condom use.
    MeSH term(s) Condoms/statistics & numerical data ; Condoms/trends ; Health Behavior ; Humans ; Los Angeles/epidemiology ; Needle Sharing/statistics & numerical data ; Needle Sharing/trends ; Risk-Taking ; Sexual Behavior/statistics & numerical data ; Substance Abuse, Intravenous/psychology
    Language English
    Publishing date 1998-05-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 645053-2
    ISSN 1944-7884 ; 1077-9450 ; 1077-9450 ; 0897-5965 ; 0894-9255 ; 1525-4135
    ISSN (online) 1944-7884 ; 1077-9450
    ISSN 1077-9450 ; 0897-5965 ; 0894-9255 ; 1525-4135
    DOI 10.1097/00042560-199805010-00010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2442: Show issues Location:
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  5. Article: Localization of human elav-like neuronal protein 1 (Hel-N1) on chromosome 9p21 by chromosome microdissection polymerase chain reaction and fluorescence in situ hybridization.

    Han, J / Knops, J F / Longshore, J W / King, P H

    Genomics

    1996  Volume 36, Issue 1, Page(s) 189–191

    Abstract: Hel-N1 is a member of the highly conserved elav family of neuronal genes. It shares considerable ...

    Abstract Hel-N1 is a member of the highly conserved elav family of neuronal genes. It shares considerable sequence homology with HuD, another human member, and both genes are expressed in brain. HuD was recently mapped to chromosome 1p34. Here, we have utilized chromosome microdissection polymerase chain reaction and fluorescence in situ hybridization to map Hel-N1 to chromosome 9p21. The different chromosomal locations of these homologous genes underscore their distinct identities.
    MeSH term(s) Chromosome Mapping/methods ; Chromosomes, Human, Pair 9/genetics ; ELAV Proteins ; ELAV-Like Protein 2 ; Genetic Techniques ; Humans ; In Situ Hybridization, Fluorescence ; Nerve Tissue Proteins/genetics ; Polymerase Chain Reaction/methods ; RNA-Binding Proteins/genetics
    Chemical Substances ELAV Proteins ; ELAV-Like Protein 2 ; ELAVL2 protein, human ; Nerve Tissue Proteins ; RNA-Binding Proteins
    Language English
    Publishing date 1996-08-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 356334-0
    ISSN 1089-8646 ; 0888-7543
    ISSN (online) 1089-8646
    ISSN 0888-7543
    DOI 10.1006/geno.1996.0444
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2367: Show issues Location:
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  6. Article: Prevalence of HIV-1 among recent arrestees in Los Angeles County, California: serial cross-sectional study, 1991-1995.

    Carpenter, C L / Longshore, D / Annon, K / Annon, J J / Anglin, M D

    Journal of acquired immune deficiency syndromes (1999)

    1999  Volume 21, Issue 2, Page(s) 172–177

    Abstract: ... estimates were relatively stable for IDU (6%), male (3%) and female arrestees (3%), arrestees who share ...

    Abstract Injection drug users (IDU), crack smokers, and commercial sex workers engage in illegal activities that place them at risk for HIV infection. The marginalized nature of these groups often limits use of customary sampling methods to assess HIV prevalence. We tested urine samples of recent arrestees to evaluate HIV prevalence of at-risk populations that are difficult to access using standard surveillance methods. We tested for HIV-1 antibodies in urine specimens of recent Los Angeles County (California, U.S.A.) arrestees as part of the Drug Use Forecasting (DUF) Program funded by the U. S. National Institute of Justice. Data are presented for 5 years of a serial cross-sectional study of arrestees. Results from 1991 through 1995 indicate a slight HIV prevalence increase among crack smokers (from 4% to 6%). Prevalence estimates were relatively stable for IDU (6%), male (3%) and female arrestees (3%), arrestees who share needles (9%), and commercial sex workers (6%). HIV status was independently associated with injection drug use, crack smoking, and ever having exchanged sex for money or drugs. Prevalence of HIV among arrestee subgroups may reflect prevalence in the community. However the benefit of using the DUF sample must be weighed against bias introduced from using nonrandom samples to estimate prevalence.
    MeSH term(s) Crack Cocaine ; Female ; HIV Antibodies/urine ; HIV Infections/epidemiology ; HIV Infections/etiology ; HIV Infections/immunology ; HIV Infections/virology ; HIV-1/immunology ; Homosexuality ; Humans ; Longitudinal Studies ; Los Angeles/epidemiology ; Male ; Odds Ratio ; Population Surveillance ; Prevalence ; Prisoners ; Prisons ; Risk Factors ; Sex Factors ; Sex Work ; Substance Abuse, Intravenous
    Chemical Substances Crack Cocaine ; HIV Antibodies
    Language English
    Publishing date 1999-06-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 645053-2
    ISSN 1944-7884 ; 1077-9450 ; 1525-4135 ; 0897-5965 ; 0894-9255
    ISSN (online) 1944-7884 ; 1077-9450
    ISSN 1525-4135 ; 0897-5965 ; 0894-9255
    Database MEDical Literature Analysis and Retrieval System OnLINE

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