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  1. Book: Cognition and acquired language disorders

    Peach, Richard K. / Shapiro, Lewis Philip

    an information processing approach

    2012  

    Author's details Richard K. Peach ; Lewis P. Shapiro
    Language English
    Size IX, 357 S. : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place St. Louis, Mo
    Publishing country United States
    Document type Book
    HBZ-ID HT017057323
    ISBN 978-0-323-07201-4 ; 0-323-07201-1
    Database Catalogue ZB MED Medicine, Health

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    2011 A 5182 order for loan Magazin

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  2. Article ; Online: Cognitive Approaches to Aphasia Treatment: Application of the Cognition of Language to Aphasia Intervention.

    Peach, Richard K

    Seminars in speech and language

    2017  Volume 38, Issue 1, Page(s) 3–4

    MeSH term(s) Aphasia/therapy ; Cognition ; Cognition Disorders/therapy ; Cognitive Therapy/methods ; Humans ; Language
    Language English
    Publishing date 2017-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604960-6
    ISSN 1098-9056 ; 0734-0478
    ISSN (online) 1098-9056
    ISSN 0734-0478
    DOI 10.1055/s-0036-1597259
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  3. Article: Cognitive Approaches to Aphasia Treatment: Application of the Cognition of Language to Aphasia Intervention

    Peach, Richard K.

    Seminars in Speech and Language

    (Cognitive Approaches to Aphasia Treatment)

    2017  Volume 38, Issue 01, Page(s) 3–4

    Series title Cognitive Approaches to Aphasia Treatment
    Language English
    Publishing date 2017-02-01
    Publisher Thieme Medical Publishers
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 604960-6
    ISSN 1098-9056 ; 0734-0478
    ISSN (online) 1098-9056
    ISSN 0734-0478
    DOI 10.1055/s-0036-1597259
    Database Thieme publisher's database

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  4. Book: Aphasia

    Peach, Richard K.

    (Clinics in communication disorders ; 2,1)

    1992  

    Author's details issue ed.: Richard K. Peach
    Series title Clinics in communication disorders ; 2,1
    Collection
    Keywords Aphasia
    Size 88 S. : Ill., graph. Darst.
    Publisher Andover
    Publishing place Reading, MA
    Publishing country United States
    Document type Book
    HBZ-ID HT004515125
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: The cognitive basis for sentence planning difficulties in discourse after traumatic brain injury.

    Peach, Richard K

    American journal of speech-language pathology

    2013  Volume 22, Issue 2, Page(s) S285–97

    Abstract: Purpose: Analyses of language production of individuals with traumatic brain injury (TBI) place increasing emphasis on microlinguistic (i.e., within-sentence) patterns. It is unknown whether the observed problems involve implementation of well-formed ... ...

    Abstract Purpose: Analyses of language production of individuals with traumatic brain injury (TBI) place increasing emphasis on microlinguistic (i.e., within-sentence) patterns. It is unknown whether the observed problems involve implementation of well-formed sentence frames or represent a fundamental linguistic disturbance in computing sentence structure. This study investigated the cognitive basis for microlinguistic deficits in individuals with TBI.
    Method: Fifteen nonaphasic individuals with severe TBI and 6 age- and education-matched non brain-injured adults participated in this study. Monologic discourse samples were analyzed for pausing patterns, mazes, errors, and abandoned utterances. Measures of cognitive abilities were correlated with the sentence measures.
    Results: The speakers with TBI produced more pauses between clauses (but not within clauses) as well as more mazes than did the non brain-injured speakers. Significant regression models were built. Raven's Coloured Progressive Matrices (Raven, 1965), a measure associated with working memory, predicted pause behavior, and Likenesses-Differences (Baker & Leland, 1967), a measure of executive function, predicted maze behavior.
    Conclusions: Sentence planning impairments following TBI are associated with deficient organization and monitoring of language representations in working memory. These findings suggest that the deficits are due to problems in the recruitment and control of attention for sentence planning. These findings bear on sentence processing models that emphasize the activation, organization, and maintenance of language representations for accurate sentence production.
    MeSH term(s) Adult ; Attention/physiology ; Brain Injuries/complications ; Brain Injuries/physiopathology ; Cognition/physiology ; Cognition Disorders/etiology ; Cognition Disorders/physiopathology ; Executive Function/physiology ; Female ; Humans ; Language Disorders/etiology ; Language Disorders/physiopathology ; Language Tests ; Linguistics ; Male ; Memory, Short-Term/physiology ; Neuropsychological Tests ; Speech Production Measurement ; Young Adult
    Language English
    Publishing date 2013-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1154406-5
    ISSN 1558-9110 ; 1058-0360
    ISSN (online) 1558-9110
    ISSN 1058-0360
    DOI 10.1044/1058-0360(2013/12-0081)
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  6. Article ; Online: Racial-Ethnic Differences in Word Fluency and Auditory Comprehension Among Persons With Poststroke Aphasia.

    Ellis, Charles / Peach, Richard K

    Archives of physical medicine and rehabilitation

    2017  Volume 98, Issue 4, Page(s) 681–686

    Abstract: Objectives: To examine aphasia outcomes and to determine whether the observed language profiles vary by race-ethnicity.: Design: Retrospective cross-sectional study using a convenience sample of persons of with aphasia (PWA) obtained from AphasiaBank, ...

    Abstract Objectives: To examine aphasia outcomes and to determine whether the observed language profiles vary by race-ethnicity.
    Design: Retrospective cross-sectional study using a convenience sample of persons of with aphasia (PWA) obtained from AphasiaBank, a database designed for the study of aphasia outcomes.
    Setting: Aphasia research laboratories.
    Participants: PWA (N=381; 339 white and 42 black individuals).
    Interventions: Not applicable.
    Main outcome measures: Western Aphasia Battery-Revised (WAB-R) total scale score (Aphasia Quotient) and subtest scores were analyzed for racial-ethnic differences. The WAB-R is a comprehensive assessment of communication function designed to evaluate PWA in the areas of spontaneous speech, auditory comprehension, repetition, and naming in addition to reading, writing, apraxia, and constructional, visuospatial, and calculation skills.
    Results: In univariate comparisons, black PWA exhibited lower word fluency (5.7 vs 7.6; P=.004), auditory word comprehension (49.0 vs 53.0; P=.021), and comprehension of sequential commands (44.2 vs 52.2; P=.012) when compared with white PWA. In multivariate comparisons, adjusted for age and years of education, black PWA exhibited lower word fluency (5.5 vs 7.6; P=.015), auditory word recognition (49.3 vs 53.3; P=.02), and comprehension of sequential commands (43.7 vs 53.2; P=.017) when compared with white PWA.
    Conclusions: This study identified racial-ethnic differences in word fluency and auditory comprehension ability among PWA. Both skills are critical to effective communication, and racial-ethnic differences in outcomes must be considered in treatment approaches designed to improve overall communication ability.
    MeSH term(s) African Americans/statistics & numerical data ; Aphasia/ethnology ; Aphasia/etiology ; Aphasia/rehabilitation ; Auditory Perceptual Disorders/ethnology ; Auditory Perceptual Disorders/etiology ; Auditory Perceptual Disorders/rehabilitation ; Cross-Sectional Studies ; European Continental Ancestry Group/statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Speech Disorders/ethnology ; Speech Disorders/etiology ; Speech Disorders/rehabilitation ; Stroke/complications ; Stroke/ethnology ; Treatment Outcome
    Language English
    Publishing date 2017-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80057-0
    ISSN 1532-821X ; 0003-9993
    ISSN (online) 1532-821X
    ISSN 0003-9993
    DOI 10.1016/j.apmr.2016.10.010
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  7. Article ; Online: Linking inter- and intra-sentential processes for narrative production following traumatic brain injury: Implications for a model of discourse processing.

    Peach, Richard K / Coelho, Carl A

    Neuropsychologia

    2016  Volume 80, Page(s) 157–164

    Abstract: Some suggest that traumatic brain injury (TBI) produces dissociation between the macrolinguistic and microlinguistic levels of discourse production. This assumption is based primarily on studies that have found preserved intersentential cohesion and/or ... ...

    Abstract Some suggest that traumatic brain injury (TBI) produces dissociation between the macrolinguistic and microlinguistic levels of discourse production. This assumption is based primarily on studies that have found preserved intersentential cohesion and/or intra-sentential processing in narratives produced by these individuals. However, few studies exist, if any, that have investigated the relationship between these processes in TBI speakers who do demonstrate such microlinguistic impairments. This study investigated the relationship between impairments of intersentential cohesion and intra-sentential processing in the discourse of 15 speakers with severe TBI. The results demonstrated a significant relationship between the production of cohesive ties and instances of intra-sentential impairment that suggests that utilization of resources for adequate cohesion appears to negatively affect intra-sentential processing following TBI. We propose that macrolinguistic and microlinguistic processes are not independent of one another, as has been proposed, but share cognitive resources that support the planning and production of both local (microlinguistic) and long-distance (macrolinguistic) relationships expressed through discourse.
    MeSH term(s) Adult ; Analysis of Variance ; Brain Injuries/complications ; Cognition Disorders/etiology ; Female ; Humans ; Language Disorders/etiology ; Linguistics ; Male ; Narration ; Reproducibility of Results ; Verbal Behavior/physiology ; Young Adult
    Language English
    Publishing date 2016-01-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 207151-4
    ISSN 1873-3514 ; 0028-3932
    ISSN (online) 1873-3514
    ISSN 0028-3932
    DOI 10.1016/j.neuropsychologia.2015.11.015
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  8. Article ; Online: Urban-Rural Differences in Service Utilization and Costs of Care for Racial-Ethnic Groups Hospitalized With Poststroke Aphasia.

    Hardy, Rose Y / Lindrooth, Richard C / Peach, Richard K / Ellis, Charles

    Archives of physical medicine and rehabilitation

    2018  Volume 100, Issue 2, Page(s) 254–260

    Abstract: Objective: Although residence is a key contributor to cost and utilization in stroke patient care, its contribution to the care of persons with aphasia (PWA) is unknown. The objective of this study was to use discharge-level hospital inpatient data to ... ...

    Abstract Objective: Although residence is a key contributor to cost and utilization in stroke patient care, its contribution to the care of persons with aphasia (PWA) is unknown. The objective of this study was to use discharge-level hospital inpatient data to examine the influence of patient residence (rural vs urban) and race-ethnicity on service utilization and cost of care among PWA.
    Design: Cross-sectional.
    Setting: Administrative data from acute care hospitals in the state of North Carolina.
    Participants: Individuals (N=4381) with poststroke aphasia.
    Interventions: N/A.
    Main outcome measures: Length of stay (LOS), speech-language pathology (SLP) service utilization, costs of care.
    Methods: The 2011-2012 Healthcare Cost and Utilization Project State Inpatient Database data were analyzed to examine the effect of rural or urban residence on LOS, SLP service utilization, as well as total inpatient and SLP service costs. These outcomes were further analyzed across both residence and racial groups (non-Hispanic white and non-Hispanic black). Outcomes were analyzed using generalized linear model.
    Results: Both rural and urban black PWA experienced longer average LOS after controlling for demographics, illness severity, and the hospital where they received care. Rural blacks experienced longer LOS, received greater SLP services, and incurred greater average total hospital costs than their rural white counterparts after adjusting for differences in their demographics and stroke or illness severity. The differences were attenuated after controlling for the hospital where they received care.
    Conclusions: For PWA, race-ethnicity has a larger effect on average total medical costs, SLP service utilization, and LOS than residence. It is unclear how and why blacks with aphasia have greater service utilization and costs in acute care, yet their aphasia outcomes are worse. Future studies are required to explore potential factors such as quality of care.
    MeSH term(s) Adult ; African Americans/statistics & numerical data ; Aged ; Aged, 80 and over ; Aphasia/ethnology ; Aphasia/etiology ; Aphasia/rehabilitation ; Cross-Sectional Studies ; Female ; Health Expenditures/statistics & numerical data ; Humans ; Length of Stay ; Male ; Middle Aged ; North Carolina ; Rural Population/statistics & numerical data ; Severity of Illness Index ; Socioeconomic Factors ; Speech-Language Pathology/economics ; Speech-Language Pathology/statistics & numerical data ; Stroke/complications ; Stroke/ethnology ; Urban Population/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2018-08-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80057-0
    ISSN 1532-821X ; 0003-9993
    ISSN (online) 1532-821X
    ISSN 0003-9993
    DOI 10.1016/j.apmr.2018.06.033
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  9. Article ; Online: Clinical Outcomes Following Language-Specific Attention Treatment Versus Direct Attention Training for Aphasia: A Comparative Effectiveness Study.

    Peach, Richard K / Beck, Katherine M / Gorman, Michelle / Fisher, Christine

    Journal of speech, language, and hearing research : JSLHR

    2019  Volume 62, Issue 8, Page(s) 2785–2811

    Abstract: Purpose This study was conducted to examine the comparative effectiveness of 2 different approaches, 1 domain-specific and the other domain-general, to language and attention rehabilitation in participants with stroke-induced aphasia. The domain-specific ...

    Abstract Purpose This study was conducted to examine the comparative effectiveness of 2 different approaches, 1 domain-specific and the other domain-general, to language and attention rehabilitation in participants with stroke-induced aphasia. The domain-specific treatment consisted of language-specific attention treatment (L-SAT), and the domain-general treatment consisted of direct attention training (DAT) using the computerized exercises included in Attention Process Training-3 (Sohlberg & Mateer, 2010). Method Four individuals with mild-moderate aphasia participated in this study. A randomized controlled cross-over single-subject design was used to assess the effectiveness of the 2 treatments administered in this study. Treatment outcomes were evaluated in terms of participants' task performance for each program, standardized language and attention measures, tests of functional abilities, and patient-reported outcomes. Results Visual comparisons demonstrated linear improvements following L-SAT and variable patterns following DAT. Omnibus effect sizes were statistically significant for 9 of the 13 L-SAT tasks. The weighted standardized effect sizes for posttreatment changes following L-SAT ranged from small to large, with the exception of 1 task. The average group gain following DAT was 5%. The Western Aphasia Battery-Revised Aphasia Quotients (Kertesz, 2007) demonstrated reliable improvements for 3 of the 4 participants following L-SAT, whereas only 1 of the participants improved reliably following DAT. The margins of improvements in functional language were substantially larger following L-SAT than DAT. Performance on the Test of Everyday Attention improved significantly for 2 participants following L-SAT and for 1 participant following DAT on selected Test of Everyday Attention (Robertson, Ward, Ridgeway, & Nimmo-Smith, 1994) subtests. Patient-reported outcomes for communication and attention following treatment favored L-SAT compared to DAT. Conclusions The results support the view that attention is allocated in ways that are particular to specific tasks rather than as a general resource that is allocated equivalently to all processing tasks. Domain-specific treatment for language deficits due to attentional impairment appears to be a suitable, if not preferable, approach for aphasia rehabilitation. Supplemental Material https://doi.org/10.23641/asha.8986427.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Aphasia/etiology ; Aphasia/psychology ; Aphasia/therapy ; Attention ; Comparative Effectiveness Research ; Cross-Over Studies ; Female ; Humans ; Language Therapy/methods ; Male ; Middle Aged ; Patient Reported Outcome Measures ; Stroke/complications ; Stroke/psychology ; Stroke Rehabilitation/methods ; Task Performance and Analysis ; Treatment Outcome
    Language English
    Publishing date 2019-07-25
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1364086-0
    ISSN 1558-9102 ; 1092-4388
    ISSN (online) 1558-9102
    ISSN 1092-4388
    DOI 10.1044/2019_JSLHR-L-18-0504
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  10. Article ; Online: IDH-mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation.

    Hong, Lih En / Wechalekar, Mihir D / Kutyna, Monika / Small, Annabelle / Lim, Kelly / Thompson-Peach, Chloe / Li, Joule J / Chhetri, Rakchha / Scott, Hamish S / Brown, Anna / Hahn, Christopher N / Yeung, David T / Sajid, Salvia / Robinson, Nirmal / Thomas, Ranjeny / Branford, Susan / D'Andrea, Richard J / Samaraweera, Saumya E / Patnaik, Mrinal /
    Proudman, Susanna / Thomas, Daniel / Kok, Chung Hoow / Shah, Mithun V / Hiwase, Devendra K

    Blood

    2024  Volume 143, Issue 18, Page(s) 1873–1877

    Abstract: Abstract: High prevalence of IDH mutations in seronegative rheumatoid arthritis (RA) with myeloid neoplasm, elevated 2-hydroxyglutarate, dysregulated innate immunity, and proinflammatory microenvironment suggests causative association between IDH ... ...

    Abstract Abstract: High prevalence of IDH mutations in seronegative rheumatoid arthritis (RA) with myeloid neoplasm, elevated 2-hydroxyglutarate, dysregulated innate immunity, and proinflammatory microenvironment suggests causative association between IDH mutations and seronegative RA. Our findings merit investigation of IDH inhibitors as therapeutics for seronegative IDH-mutated RA.
    MeSH term(s) Humans ; Arthritis, Rheumatoid/immunology ; Arthritis, Rheumatoid/genetics ; Immunity, Innate ; Isocitrate Dehydrogenase/genetics ; Mutation ; Male ; Female ; Middle Aged ; Aged
    Chemical Substances Isocitrate Dehydrogenase (EC 1.1.1.41) ; IDH1 protein, human (EC 1.1.1.42.)
    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2023023593
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