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  1. Article ; Online: Don't let the genie out of the bottle!

    Kumar, Shaji

    Blood

    2024  Volume 143, Issue 7, Page(s) 564–566

    MeSH term(s) Humans ; Multiple Myeloma ; Patients ; Methylmethacrylates
    Chemical Substances Genie (80106-42-9) ; Methylmethacrylates
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2023023293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: One disease, many faces.

    Kumar, Shaji

    Haematologica

    2023  Volume 108, Issue 5, Page(s) 1213–1215

    Language English
    Publishing date 2023-05-01
    Publishing country Italy
    Document type Editorial
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2022.281417
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online ; E-Book: Biology and management of unusual plasma cell dyscrasias

    Zimmerman, Todd M. / Kumar, Shaji K.

    2017  

    Author's details Todd M. Zimmerman ; Shaji K. Kumar ed
    Language English
    Size XI, 202 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place New York
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019098839
    ISBN 978-1-4419-6848-7 ; 9781441968470 ; 1-4419-6848-2 ; 1441968474
    DOI 10.1007/978-1-4419-6848-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Multiple Myeloma: From Baby Steps to Giant Strides.

    Kumar, Shaji

    JCO oncology practice

    2021  Volume 17, Issue 7, Page(s) 419–420

    MeSH term(s) Humans ; Multiple Myeloma/therapy
    Language English
    Publishing date 2021-06-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3028198-2
    ISSN 2688-1535 ; 2688-1527
    ISSN (online) 2688-1535
    ISSN 2688-1527
    DOI 10.1200/OP.21.00327
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  5. Article: Interscalene Brachial Plexus Block for Reduction of Shoulder Dislocation: Safety Concerns in the Emergency Department.

    Barik, Amiya Kumar / Mohanty, Chitta Ranjan / Radhakrishnan, Rakesh Vadakkethil / Shaji, Ijas Muhammed

    The Journal of emergency medicine

    2024  Volume 66, Issue 2, Page(s) 260–261

    MeSH term(s) Humans ; Shoulder ; Brachial Plexus Block ; Emergency Service, Hospital
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Letter
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2023.08.012
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  6. Article ; Online: High-risk multiple myeloma: Redefining genetic, clinical, and functional high-risk disease in the era of molecular medicine and immunotherapy.

    Rees, Matthew J / Kumar, Shaji

    American journal of hematology

    2024  

    Abstract: Multiple myeloma (MM) exhibits significant heterogeneity in its presentation, genetics, and treatment response. Despite therapeutic advances, some patients continue to relapse early (ER, <18-months) and rapidly cycle through therapies. Myriad prognostic ... ...

    Abstract Multiple myeloma (MM) exhibits significant heterogeneity in its presentation, genetics, and treatment response. Despite therapeutic advances, some patients continue to relapse early (ER, <18-months) and rapidly cycle through therapies. Myriad prognostic factors have been identified and incorporated into risk stratification models; however, these produce discordant, often three-tiered outputs that fail to identify many patients destined for ER. Treatment strategies are increasingly focused on disease biology and trials enriched for high-risk (HR)MM, but consensus on the minimum required testing and a succinct, specific, and clinically meaningful definition for HRMM remains elusive. We review the risk-factors, definitions, and future directions for HRMM.
    Language English
    Publishing date 2024-04-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.27327
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  7. Article ; Online: New Therapies on the Horizon for Relapsed Refractory Multiple Myeloma.

    Abdallah, Nadine / Kumar, Shaji K

    Hematology/oncology clinics of North America

    2024  Volume 38, Issue 2, Page(s) 511–532

    Abstract: Despite improved treatments, most patients with multiple myeloma (MM) will experience relapse. Several novel agents have demonstrated activity and tolerability in early phase clinical trials. Venetoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor with ... ...

    Abstract Despite improved treatments, most patients with multiple myeloma (MM) will experience relapse. Several novel agents have demonstrated activity and tolerability in early phase clinical trials. Venetoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor with activity in patients with t(11;14) and/or Bcl-2 expression. Iberdomide and mezigdomide are cereblon E3 ligase modulators with higher potency, immunomodulatory, and antiproliferative activity compared with lenalidomide and pomalidomide. They have shown promising activity in heavily pretreated patients. Modakafusp alfa is an immunocytokine that targets interferons to CD38+ cells. It has demonstrated single agent activity in relapsed/refractory MM in the phase 1 setting.
    MeSH term(s) Humans ; Multiple Myeloma/pathology ; Neoplasm Recurrence, Local/drug therapy ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents/pharmacology ; Lenalidomide/therapeutic use ; Proto-Oncogene Proteins c-bcl-2 ; Dexamethasone/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use
    Chemical Substances Antineoplastic Agents ; Lenalidomide (F0P408N6V4) ; Proto-Oncogene Proteins c-bcl-2 ; Dexamethasone (7S5I7G3JQL)
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 93115-9
    ISSN 1558-1977 ; 0889-8588
    ISSN (online) 1558-1977
    ISSN 0889-8588
    DOI 10.1016/j.hoc.2023.12.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Reply to E.R.S. Cliff et al.

    D'Souza, Anita / Kumar, Shaji

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2023  Volume 41, Issue 10, Page(s) 1951–1952

    Language English
    Publishing date 2023-01-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.22.02691
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  9. Article ; Online: Post-intubation analgesia and sedation following succinylcholine vs. rocuronium in the emergency department; some concerns.

    Barik, Amiya Kumar / Mohanty, Chitta Ranjan / Radhakrishnan, Rakesh Vadakkethil / Shaji, Ijas Muhammed

    The American journal of emergency medicine

    2023  Volume 73, Page(s) 205–206

    Language English
    Publishing date 2023-09-23
    Publishing country United States
    Document type Letter
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2023.09.028
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  10. Article ; Online: Comment on whole-body cooling effectiveness of cold intravenous saline following exercise hyperthermia: A randomized trial.

    Shaji, Ijas Muhammed / Barik, Amiya Kumar / Radhakrishnan, Rakesh Vadakkethil / Mohanty, Chitta Ranjan

    The American journal of emergency medicine

    2023  Volume 73, Page(s) 203–204

    MeSH term(s) Humans ; Body Temperature ; Exercise ; Hyperthermia, Induced
    Language English
    Publishing date 2023-09-24
    Publishing country United States
    Document type Randomized Controlled Trial ; Letter ; Comment
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2023.09.029
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