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  1. Article ; Online: Chemical Spill Encircling Using a Quadrotor and Autonomous Surface Vehicles: A Distributed Cooperative Approach.

    Jacinto, Marcelo / Cunha, Rita / Pascoal, António

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 6

    Abstract: This article addresses the problem of formation control of a quadrotor and one (or more) marine vehicles operating at the surface of the water with the end goal of encircling the boundary of a chemical spill, enabling such vehicles to carry and release ... ...

    Abstract This article addresses the problem of formation control of a quadrotor and one (or more) marine vehicles operating at the surface of the water with the end goal of encircling the boundary of a chemical spill, enabling such vehicles to carry and release chemical dispersants used during ocean cleanup missions to break up oil molecules. Firstly, the mathematical models of the Medusa class of marine robots and quadrotor aircrafts are introduced, followed by the design of single vehicle motion controllers that allow these vehicles to follow a parameterised path individually using Lyapunov-based techniques. At a second stage, a distributed controller using event-triggered communications is introduced, enabling the vehicles to perform cooperative path following missions according to a pre-defined geometric formation. In the next step, a real-time path planning algorithm is developed that makes use of a camera sensor, installed on-board the quadrotor. This sensor enables the detection in the image of which pixels encode parts of a chemical spill boundary and use them to generate and update, in real time, a set of smooth B-spline-based paths for all the vehicles to follow cooperatively. The performance of the complete system is evaluated by resorting to 3-D simulation software, making it possible to visually simulate a chemical spill. Results from real water trials are also provided for parts of the system, where two Medusa vehicles are required to perform a static lawn-mowing path following mission cooperatively at the surface of the water.
    Language English
    Publishing date 2022-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22062178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Editorial overview: Cell reprogramming, regeneration and repair.

    Jacinto, António / Liu, Pentao

    Current opinion in genetics & development

    2020  Volume 64, Page(s) iii–vi

    MeSH term(s) Animals ; Cellular Reprogramming ; Humans ; Regeneration ; Wound Healing
    Language English
    Publishing date 2020-12-23
    Publishing country England
    Document type Editorial
    ZDB-ID 1077312-5
    ISSN 1879-0380 ; 0959-437X
    ISSN (online) 1879-0380
    ISSN 0959-437X
    DOI 10.1016/j.gde.2020.09.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effects of a 24-Week Low-Cost Multicomponent Exercise Program on Health-Related Functional Fitness in the Community-Dwelling Aged and Older Adults.

    Rodrigues, Filipe / Jacinto, Miguel / Figueiredo, Nuno / Monteiro, António Miguel / Forte, Pedro

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 2

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Aged ; Humans ; Middle Aged ; Physical Fitness ; Independent Living ; Hand Strength ; Postural Balance ; Time and Motion Studies ; Exercise Therapy
    Language English
    Publishing date 2023-02-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59020371
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: COVID-19 Myopericarditis in a Young Healthy Male.

    Bandeira, Matilde / Serrazina, Juliana / Santos, Carolina António / Jacinto, Nuno / Pais de Lacerda, António

    European journal of case reports in internal medicine

    2022  Volume 9, Issue 5, Page(s) 3361

    Abstract: SARS-CoV-2 infection can present in different clinical forms, most commonly as bilateral pneumonia, but also with pericardial/myocardial involvement. Cardiac involvement in COVID-19 is associated with worse outcomes. The authors report a case of ... ...

    Abstract SARS-CoV-2 infection can present in different clinical forms, most commonly as bilateral pneumonia, but also with pericardial/myocardial involvement. Cardiac involvement in COVID-19 is associated with worse outcomes. The authors report a case of myopericarditis as the primary manifestation of SARS-CoV-2 infection in a 20-year-old male patient with no known cardiovascular (CV) disorders or risk factors. The patient presented with pleuritic chest pain and high fever, with no respiratory symptoms. Electrocardiogram (ECG) and echocardiogram changes were consistent with pericarditis; concomitant elevation of cardiac enzymes revealed myocardial involvement. The patient had a slow but favourable evolution with no apparent impact on cardiac function. Other causes of myopericarditis were excluded and SARS-CoV-2 admitted as the most likely aetiological agent. This case highlights possible cardiac involvement in SARS-CoV-2 infection with little or no pulmonary disease in a young healthy patient. Such systemic and potentially troublesome manifestations of COVID-19 are increasingly being described.
    Learning points: Acute myopericarditis is a possible manifestation of SARS-CoV-2 infection.SARS-CoV-2 cardiac involvement may occur both in older and in younger previously healthy subjects, and could be more frequent than expected.Further investigation should address the prevalence of myocardium and pericardium involvement in COVID-19 patients, as well as its complications, sequelae and prognostic value for both older and young patients.
    Language English
    Publishing date 2022-05-23
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2022_003361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: COVID-19 Myopericarditis in a Young Healthy Male

    Matilde Bandeira / Juliana Serrazina / Carolina António Santos / Nuno Jacinto / António Pais de Lacerda

    European Journal of Case Reports in Internal Medicine (2022)

    2022  

    Abstract: SARS-CoV-2 infection can present in different clinical forms, most commonly as bilateral pneumonia, but also with pericardial/myocardial involvement. Cardiac involvement in COVID-19 is associated with worse outcomes. The authors report a case of ... ...

    Abstract SARS-CoV-2 infection can present in different clinical forms, most commonly as bilateral pneumonia, but also with pericardial/myocardial involvement. Cardiac involvement in COVID-19 is associated with worse outcomes. The authors report a case of myopericarditis as the primary manifestation of SARS-CoV-2 infection in a 20-year-old male patient with no known cardiovascular (CV) disorders or risk factors. The patient presented with pleuritic chest pain and high fever, with no respiratory symptoms. Electrocardiogram (ECG) and echocardiogram changes were consistent with pericarditis; concomitant elevation of cardiac enzymes revealed myocardial involvement. The patient had a slow but favourable evolution with no apparent impact on cardiac function. Other causes of myopericarditis were excluded and SARS-CoV-2 admitted as the most likely aetiological agent. This case highlights possible cardiac involvement in SARS-CoV-2 infection with little or no pulmonary disease in a young healthy patient. Such systemic and potentially troublesome manifestations of COVID-19 are increasingly being described.
    Keywords myopericarditis ; covid-19 ; sars-cov-2 ; Medicine ; R
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher SMC MEDIA SRL
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Herbicide selectivity on teak seedlings (Tectona grandis L.f)

    Antônio José Plácido de Mello Mello / Cicero Jacinto da Silva Neto

    Diversitas Journal, Vol 8, Iss

    2023  Volume 2

    Abstract: One of the factors that interfere in the productivity of a forest culture, the knowledge of the selectivity of the product to the culture is essential to eliminate or limit the injuries caused by the product to the species of interest. The experiment was ...

    Abstract One of the factors that interfere in the productivity of a forest culture, the knowledge of the selectivity of the product to the culture is essential to eliminate or limit the injuries caused by the product to the species of interest. The experiment was installed at the IFAL campus Maceió, in Maceió, Alagoas, with the objective of evaluating the selectivity of saflufenacil and glyphosate in teak seedlings from seeds, through morphological, physiological and visual analysis. With Entirely Random Blocks (DBC) with five repetitions; the treatments were: Saflufenacil (100 gha-1 of active ingredient), Glyphosate (1000 gha-1 ia), association of Saflufenacil and Glyphosate (100 gha-1 ia + 1000 gha-1 ia) and the control (the control without application of herbicides). The results obtained in the variables allow us to conclude that there is selectivity between the treatments observed in the evaluation period.
    Keywords Comportamento ; Manejo ; Sustentabilidade ; Biologia ; Education ; L ; Science ; Q ; Social Sciences ; H
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher Universidade Estadual de Alagoas
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: LEVANTAMENTO ETNOBOTÂNICO DE PLANTAS MEDICINAIS UTILIZADAS PELA COMUNIDADE DE NACUALE, NO PARQUE NACIONAL DAS QUIRIMBAS, MOÇAMBIQUE

    Alexandre Jacinto Muchaia / Salvador José António Nanvonamuquitxo

    Nativa, Vol 9, Iss

    2021  Volume 5

    Abstract: A presente pesquisa teve como objectivo fazer o levantamento Etnobotânico de plantas com poder medicinal utilizadas pela comunidade de Nacuale no Distrito de Ancuabe, Cabo Delgado, Moçambique. Foram realizadas entrevistas com 88 chefes de agregados ... ...

    Abstract A presente pesquisa teve como objectivo fazer o levantamento Etnobotânico de plantas com poder medicinal utilizadas pela comunidade de Nacuale no Distrito de Ancuabe, Cabo Delgado, Moçambique. Foram realizadas entrevistas com 88 chefes de agregados familiares com propósito de compreender além do perfil socio -económico, as principais plantas usadas para o tratamento de doenças mais frequentes da comunidade desta localidade. As plantas citadas como medicinal foram identificadas e organizadas em função dos valores de concordância de uso principal-CUPc. Por sua vez, foi determinada a diversidade de plantas medicinais usadas na região, bem como as doenças para a qual cada uma das plantas é usada. Cerca de 45% da população que vive na localidade de Nacuale é pobre (rendimento familiar inferior a 15 $/mês). As principais actividades de renda são a agricultura familiar (68%), caça (20%) e pequenos negócios (12%). O difícil acesso aos serviços de saúde convencional faz com que a maioria das populações optem pela medicina tradicional para tratamento de doenças. A Mangifera indica Wall (46,0%), Afizelia quanzensis Welw (37,5%), Moringa oleífera Lam (29,2%) e Carica papaya L (20,8%) foram as espécies mais citadas dentre as utilizadas para o tratamento de doenças. As populações demonstraram ainda ter conhecimento de diversas espécies de plantas medicinais da região (H’=3,04 e J’=0,93), enquanto que as doenças comumente tratadas com recurso destas plantas são a malária (20%), dores de estomago (18 %), dores de cabeça (16%) e reumatismo (13%). Na localidade de Nacuale, o uso da medicina tradicional é ainda uma opção viável pela dificuldade de acesso aos serviços de saúde convencional, agravado pelo baixo nível de escolaridade, pobreza e aspectos socioculturais. As plantas são usadas para tratamento de doenças mais frequentes nessa região. Palavra chaves: etnobotânica; plantas medicinais; Cabo Delgado - Moçambique. Ethnobotanical assessment of medicinal plants used by the community of Nacuale, in the Quirimbas National Park, ...
    Keywords Etnobotânica ; plantas medicinais ; Nacuale-Ancuabe ; Cabo Delgado-Moçambique ; Agriculture ; S ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher Universidade Federal de Mato Grosso (UFMT)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The right time for senescence.

    Paramos-de-Carvalho, Diogo / Jacinto, Antonio / Saúde, Leonor

    eLife

    2021  Volume 10

    Abstract: Cellular senescence is a highly complex and programmed cellular state with diverse and, at times, conflicting physiological and pathological roles across the lifespan of an organism. Initially considered a cell culture artifact, senescence evolved from ... ...

    Abstract Cellular senescence is a highly complex and programmed cellular state with diverse and, at times, conflicting physiological and pathological roles across the lifespan of an organism. Initially considered a cell culture artifact, senescence evolved from an age-related circumstance to an intricate cellular defense mechanism in response to stress, implicated in a wide spectrum of biological processes like tissue remodelling, injury and cancer. The development of new tools to study senescence in vivo paved the way to uncover its functional roles in various frameworks, which are sometimes hard to reconcile. Here, we review the functional impact of senescent cells on different organismal contexts. We provide updated insights on the role of senescent cells in tissue repair and regeneration, in which they essentially modulate the levels of fibrosis and inflammation, discussing how "time" seems to be the key maestro of their effects. Finally, we overview the current clinical research landscape to target senescent cells and contemplate its repercussions on this fast-evolving field.
    MeSH term(s) Aging/physiology ; Animals ; Cellular Senescence/physiology ; Fibrosis/physiopathology ; Humans ; Inflammation ; Regeneration/physiology
    Language English
    Publishing date 2021-11-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.72449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Efecto de un multivitamínico sobre la resistencia a la insulina, inflamación y estrés oxidante en un modelo de obesidad inducida en ratas Wistar.

    Palma-Jacinto, José Antonio / Santiago-Roque, Isela / Coutiño-Rodríguez, María Del Rocío / Arroyo-Helguera, Omar Elind

    Nutricion hospitalaria

    2023  Volume 40, Issue 6, Page(s) 1183–1191

    Abstract: Introduction: Introduction: excessive accumulation of adipose tissue is accompanied by alterations in the inflammatory state and increased oxidative stress, and these variables are associated with insulin resistance and increased glucose and insulin ... ...

    Title translation Effect of a multivitamin on insulin resistance, inflammation, and oxidative stress in a Wistar rat model of induced obesity.
    Abstract Introduction: Introduction: excessive accumulation of adipose tissue is accompanied by alterations in the inflammatory state and increased oxidative stress, and these variables are associated with insulin resistance and increased glucose and insulin levels. On the other hand, vitamins and minerals reinforce the antioxidant and inflammatory capacity, for this reasons we propose that they could contribute to the control of insulin resistance, glucose and lipid metabolism in a rat model of obesity. Objective: to analyze the effect of a multivitamin supplement on markers of insulin resistance, inflammation, and oxidative stress in obese rats on a cafeteria diet. Methods: thirty-five 28-day-old male Wistar rats were randomly divided into four groups: 1, standard diet control; 2, standard diet plus multivitamin; 3, obese on a cafeteria diet; and 4, obese on a cafeteria diet plus multivitamin. After the treatments, glucose levels, HbA1c, insulin, TNF-α, IL-6, oxidative stress and lipid profile were analyzed by colorimetric methods, as well as the percentage of adipose tissue, Homeostasis Model Assessment (HOMA) index y Quantitative Insulin Sensitivity Check Index (QUICKI). Results: multivitamin supplementation significantly decreased visceral adipose tissue, HOMA index, glucose, HbA1c, oxidant stress, and inflammatory markers in the obese plus multivitamin rat group, compared with the obese cafeteria diet rat group and the standard diet rat control group. However, the group that was administered only the multivitamin without the cafeteria diet had increased levels of total adipose tissue, glucose, and oxidative stress, as well as the QUICKI index relative to the control group with the standard diet. Conclusion: co-administration of a multivitamin supplement may improve insulin sensitivity, glucose metabolism and lipid profile; strengthen antioxidant status; and decrease inflammation during weight gain. However, it was not expected that added sugars in multivitamin supplement can also increase total adipose tissue, oxidative stress and glucose levels, so it is suggested to use sugar-free multivitamins in the future.
    MeSH term(s) Male ; Rats ; Animals ; Rats, Wistar ; Insulin Resistance ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Glycated Hemoglobin ; Obesity/drug therapy ; Obesity/metabolism ; Oxidative Stress ; Inflammation/drug therapy ; Inflammation/metabolism ; Insulin/metabolism ; Vitamins/pharmacology ; Vitamins/therapeutic use ; Lipids ; Glucose
    Chemical Substances Antioxidants ; Glycated Hemoglobin ; Insulin ; Vitamins ; Lipids ; Glucose (IY9XDZ35W2)
    Language Spanish
    Publishing date 2023-10-29
    Publishing country Spain
    Document type English Abstract ; Journal Article
    ZDB-ID 1481223-x
    ISSN 1699-5198 ; 0212-1611
    ISSN (online) 1699-5198
    ISSN 0212-1611
    DOI 10.20960/nh.04621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The right time for senescence

    Diogo Paramos-de-Carvalho / Antonio Jacinto / Leonor Saúde

    eLife, Vol

    2021  Volume 10

    Abstract: Cellular senescence is a highly complex and programmed cellular state with diverse and, at times, conflicting physiological and pathological roles across the lifespan of an organism. Initially considered a cell culture artifact, senescence evolved from ... ...

    Abstract Cellular senescence is a highly complex and programmed cellular state with diverse and, at times, conflicting physiological and pathological roles across the lifespan of an organism. Initially considered a cell culture artifact, senescence evolved from an age-related circumstance to an intricate cellular defense mechanism in response to stress, implicated in a wide spectrum of biological processes like tissue remodelling, injury and cancer. The development of new tools to study senescence in vivo paved the way to uncover its functional roles in various frameworks, which are sometimes hard to reconcile. Here, we review the functional impact of senescent cells on different organismal contexts. We provide updated insights on the role of senescent cells in tissue repair and regeneration, in which they essentially modulate the levels of fibrosis and inflammation, discussing how “time” seems to be the key maestro of their effects. Finally, we overview the current clinical research landscape to target senescent cells and contemplate its repercussions on this fast-evolving field.
    Keywords senescence ; time ; tissue remodelling ; pathophysiology ; senotherapies ; Medicine ; R ; Science ; Q ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher eLife Sciences Publications Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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