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  1. Article ; Online: Controlled human drug administration studies are necessary to define the THC-sparing effects of CBD and other cannabis constituents.

    Pabon, Elisa / Cooper, Ziva D

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2023  Volume 48, Issue 6, Page(s) 850–851

    MeSH term(s) Humans ; Cannabis ; Hallucinogens/pharmacology ; Dronabinol/pharmacology ; Cannabinoid Receptor Agonists ; Cannabidiol/pharmacology
    Chemical Substances Hallucinogens ; Dronabinol (7J8897W37S) ; Cannabinoid Receptor Agonists ; Cannabidiol (19GBJ60SN5)
    Language English
    Publishing date 2023-02-01
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-023-01538-y
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    Zs.A 2379: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Understanding Cannabis Use Disorder Diagnoses in the U.S. Veterans Health Administration in the Era of Legalization.

    Lake, Stephanie / Cooper, Ziva D

    The American journal of psychiatry

    2022  Volume 179, Issue 10, Page(s) 702–704

    MeSH term(s) Cannabis ; Humans ; Marijuana Abuse/diagnosis ; Marijuana Abuse/epidemiology ; Marijuana Smoking ; Substance-Related Disorders ; Veterans ; Veterans Health
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.20220675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui I Zs.30: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Cannabis Use and Sharing Practices Among Sexual Minority and Heterosexual Individuals During the COVID-19 Pandemic.

    Assaf, Ryan D / Javanbakht, Marjan / Gorbach, Pamina M / Cooper, Ziva D

    LGBT health

    2023  Volume 10, Issue 7, Page(s) 514–525

    Abstract: Purpose: ...

    Abstract Purpose:
    MeSH term(s) Adult ; Humans ; Male ; Female ; United States/epidemiology ; Heterosexuality ; Pandemics ; Cannabis ; COVID-19/epidemiology ; Cross-Sectional Studies ; Sexual and Gender Minorities
    Language English
    Publishing date 2023-05-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2727303-9
    ISSN 2325-8306 ; 2325-8292
    ISSN (online) 2325-8306
    ISSN 2325-8292
    DOI 10.1089/lgbt.2022.0236
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  4. Article ; Online: Sex differences in the subjective and reinforcing effects of smoked cannabis.

    Lake, Stephanie / Haney, Margaret / Cooper, Ziva D

    Addiction biology

    2023  Volume 28, Issue 7, Page(s) e13301

    Abstract: Preclinical studies have shown sex-based differences in the reinforcing effects of cannabinoid 1 receptor agonists such as delta-9-tetrahydrocannabinol (THC). This study sought to test whether these sex differences translate to humans by assessing the ... ...

    Abstract Preclinical studies have shown sex-based differences in the reinforcing effects of cannabinoid 1 receptor agonists such as delta-9-tetrahydrocannabinol (THC). This study sought to test whether these sex differences translate to humans by assessing the subjective and reinforcing effects of smoked cannabis in male and female volunteers. We pooled data (n = 68; 55M, 13F) from two within-subject randomized controlled trials of healthy, ≥weekly cannabis users comparing the subjective and reinforcing effects of smoked active (~25 mg THC) versus placebo cannabis (0-mg THC). Subjective ratings of drug effects and mood were measured using visual analogue scales, and reinforcing effects were measured with a cannabis self-administration task. Sex-dependent outcomes were explored using generalized linear mixed models. Under active cannabis conditions, female participants reported greater reductions from baseline in cannabis craving and significantly higher cannabis-specific ratings of strength, liking, willingness to take again and good effect, compared with males (interaction p < 0.05). Placebo and active cannabis were self-administered by 22% and 36% of male participants, respectively, and by 15% and 54% of female participants, respectively. Receipt of active cannabis significantly increased likelihood of self-administration (p = 0.011), but a sex difference was not detected (p = 0.176). Although females were more sensitive to certain positive subjective effects of active cannabis, they were not more likely than males to self-administer it. These findings highlight the need to test sex differences as a primary objective in experimental studies and may shed light on accelerated trajectories from initiation to cannabis use disorder observed among women.
    MeSH term(s) Female ; Humans ; Male ; Affect ; Cannabinoid Receptor Agonists/pharmacology ; Cannabis ; Marijuana Smoking ; Randomized Controlled Trials as Topic
    Chemical Substances Cannabinoid Receptor Agonists
    Language English
    Publishing date 2023-06-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1324314-7
    ISSN 1369-1600 ; 1355-6215
    ISSN (online) 1369-1600
    ISSN 1355-6215
    DOI 10.1111/adb.13301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4586: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Changes in medical and non-medical cannabis use among United States adults before and during the COVID-19 pandemic.

    Assaf, Ryan D / Gorbach, Pamina M / Cooper, Ziva D

    The American journal of drug and alcohol abuse

    2022  Volume 48, Issue 3, Page(s) 321–327

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adult ; COVID-19 ; Cannabis ; Female ; Humans ; Male ; Medical Marijuana/therapeutic use ; Pandemics ; SARS-CoV-2 ; United States/epidemiology
    Chemical Substances Medical Marijuana
    Language English
    Publishing date 2022-02-07
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 193086-2
    ISSN 1097-9891 ; 0095-2990
    ISSN (online) 1097-9891
    ISSN 0095-2990
    DOI 10.1080/00952990.2021.2007257
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1137: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Changements observés au Canada dans la consommation de cannabis à des fins médicales pendant la pandémie de COVID-19

    Stephanie Lake / Ziva D. Cooper / Kaye Ong / Philippe Lucas

    Promotion de la santé et prévention des maladies chroniques au Canada, Vol 43, Iss 3, Pp 128-

    2023  Volume 139

    Abstract: ... Bien que l’on ait observé une augmentation des cas d’usage non médical de certaines substances ... Nous avons exploré les corrélats d’une augmentation de fréquence de consommation de cannabis ... à des fins médicales sont notamment le genre féminin, un âge plus jeune, une perte d’emploi liée ...

    Abstract IntroductionLa pandémie de COVID-19 a eu des effets négatifs généralisés sur la santé, notamment une perte de sécurité matérielle et une exacerbation des maladies mentales chez les populations à risque. Bien que l’on ait observé une augmentation des cas d’usage non médical de certaines substances, dont le cannabis, dans des échantillons de la population canadienne, aucune étude n’a porté sur les changements dans la consommation de cannabis à des fins médicales au Canada pendant la pandémie de COVID. MéthodologieLes données ont été tirées de l’Enquête canadienne sur le cannabis de 2021, une enquête en ligne réalisée en mai 2021 auprès de personnes autorisées à utiliser du cannabis à des fins médicales et qui ont été recrutées par le biais de l’un des deux producteurs de cannabis à usage médical autorisés au Canada. Nous avons eu recours à des tests de McNemar pour comparer la fréquence de consommation de cannabis à des fins médicales au cours des trois mois ayant précédé la pandémie et la fréquence de consommation de cannabis à des fins médicales pendant la pandémie. Nous avons exploré les corrélats d’une augmentation de fréquence de consommation de cannabis depuis le début de la pandémie dans des modèles logistiques à deux variables et à variables multiples. RésultatsAu total, 2 697 répondants (49,1 % de femmes) ont répondu à l’enquête. La consommation quotidienne de cannabis à des fins médicales a augmenté légèrement, mais de façon statistiquement significative, entre la période prépandémique (83,2 %) et la période pandémique (90,3 % au moment de l’enquête; p < 0,001). Les facteurs associés de manière statistiquement significative à l’augmentation de la fréquence de consommation de cannabis à des fins médicales sont notamment le genre féminin, un âge plus jeune, une perte d’emploi liée à la pandémie, la consommation de cannabis principalement pour la gestion de sa santé mentale, l’usage de médicaments sur ordonnance et la consommation de cannabis à des fins non médicales (p < 0,05). ConclusionDepuis le ...
    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Agence de la santé publique du Canada
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Shifts in medical cannabis use in Canada during the COVID-19 pandemic

    Stephanie Lake / Ziva D. Cooper / Kaye Ong / Philippe Lucas

    Health Promotion and Chronic Disease Prevention in Canada, Vol 43, Iss 3, Pp 119-

    2023  Volume 129

    Abstract: IntroductionThe COVID-19 pandemic has had widespread secondary negative health impacts including loss of material security and exacerbation of mental illness in at-risk populations. While increases in the nonmedical use of certain substances, including ... ...

    Abstract IntroductionThe COVID-19 pandemic has had widespread secondary negative health impacts including loss of material security and exacerbation of mental illness in at-risk populations. While increases in the nonmedical use of certain substances, including cannabis, have been observed in samples of the Canadian population, no research has documented COVID-concurrent shifts in medical cannabis use in Canada. MethodsData were derived from the 2021 Canadian Cannabis Patient Survey, an online survey administered in May 2021 to people authorized to use medical cannabis recruited from one of two Canadian licensed medical cannabis producers. McNemar tests assessed for changes in past 3-month medical cannabis frequency from before to during the pandemic. We explored correlates of increasing frequency of cannabis use since before the pandemic in bivariable and multivariable logistic models. ResultsIn total, 2697 respondents (49.1% women) completed the survey. Daily medical cannabis use increased slightly but significantly from before the pandemic (83.2%) to during the pandemic (90.3% at time of survey; p < 0.001). Factors significantly associated with increasing frequency of medical cannabis use included female gender, younger age, pandemic-related job loss, primary cannabis use to manage mental health, prescription drug use and nonmedical cannabis use (p < 0.05). ConclusionThere were slight shifts towards higher frequency of medical cannabis use after the onset of the COVID-19 pandemic. While short- and long-term impacts of cannabis use on pandemic-related mental distress are unknown, clinicians working with patients who use medical cannabis should be aware of possible changes in use patterns during the pandemic.
    Keywords Medicine (General) ; R5-920
    Subject code 310
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Public Health Agency of Canada
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Selective Changes in Medical Cannabis Use Early in the COVID-19 Pandemic: Findings from a Web-Based Sample of Adults in the United States.

    Lake, Stephanie / Assaf, Ryan D / Gorbach, Pamina M / Cooper, Ziva D

    Cannabis and cannabinoid research

    2022  Volume 8, Issue 1, Page(s) 174–183

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adult ; Female ; Humans ; United States ; Medical Marijuana ; Pandemics ; Retrospective Studies ; COVID-19 ; Cannabis ; Hallucinogens ; Cannabinoid Receptor Agonists ; Internet
    Chemical Substances Medical Marijuana ; Hallucinogens ; Cannabinoid Receptor Agonists
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2867624-5
    ISSN 2378-8763 ; 2578-5125
    ISSN (online) 2378-8763
    ISSN 2578-5125
    DOI 10.1089/can.2021.0115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Changes in Immune-Related Biomarkers and Endocannabinoids as a Function of Frequency of Cannabis Use in People Living With and Without HIV.

    Murray, Conor H / Javanbakht, Marjan / Cho, Grace D / Gorbach, Pamina M / Fulcher, Jennifer A / Cooper, Ziva D

    Cannabis and cannabinoid research

    2023  

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-04-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2867624-5
    ISSN 2378-8763 ; 2578-5125
    ISSN (online) 2378-8763
    ISSN 2578-5125
    DOI 10.1089/can.2022.0287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Shifts in medical cannabis use in Canada during the COVID-19 pandemic.

    Lake, Stephanie / Cooper, Ziva D / Ong, Kaye / Lucas, Philippe

    Health promotion and chronic disease prevention in Canada : research, policy and practice

    2023  Volume 43, Issue 3, Page(s) 119–129

    Abstract: Introduction: The COVID-19 pandemic has had widespread secondary negative health impacts including loss of material security and exacerbation of mental illness in at-risk populations. While increases in the nonmedical use of certain substances, ... ...

    Title translation Changements observés au Canada dans la consommation de cannabis à des fins médicales pendant la pandémie de COVID-19.
    Abstract Introduction: The COVID-19 pandemic has had widespread secondary negative health impacts including loss of material security and exacerbation of mental illness in at-risk populations. While increases in the nonmedical use of certain substances, including cannabis, have been observed in samples of the Canadian population, no research has documented COVID-concurrent shifts in medical cannabis use in Canada.
    Methods: Data were derived from the 2021 Canadian Cannabis Patient Survey, an online survey administered in May 2021 to people authorized to use medical cannabis recruited from one of two Canadian licensed medical cannabis producers. McNemar tests assessed for changes in past 3-month medical cannabis frequency from before to during the pandemic. We explored correlates of increasing frequency of cannabis use since before the pandemic in bivariable and multivariable logistic models.
    Results: In total, 2697 respondents (49.1% women) completed the survey. Daily medical cannabis use increased slightly but significantly from before the pandemic (83.2%) to during the pandemic (90.3% at time of survey; p < 0.001). Factors significantly associated with increasing frequency of medical cannabis use included female gender, younger age, pandemic-related job loss, primary cannabis use to manage mental health, prescription drug use and nonmedical cannabis use (p < 0.05).
    Conclusion: There were slight shifts towards higher frequency of medical cannabis use after the onset of the COVID-19 pandemic. While short- and long-term impacts of cannabis use on pandemic-related mental distress are unknown, clinicians working with patients who use medical cannabis should be aware of possible changes in use patterns during the pandemic.
    MeSH term(s) Humans ; Female ; Male ; Medical Marijuana/therapeutic use ; COVID-19/epidemiology ; Pandemics ; Canada/epidemiology ; Substance-Related Disorders/epidemiology ; Cannabis
    Chemical Substances Medical Marijuana
    Language French
    Publishing date 2023-03-16
    Publishing country Canada
    Document type Journal Article
    ISSN 2368-738X
    ISSN (online) 2368-738X
    DOI 10.24095/hpcdp.43.3.02
    Database MEDical Literature Analysis and Retrieval System OnLINE

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