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Article: Considering Burnout and Well-Being: Emergency Medicine Resident Shift Scheduling Platform and Satisfaction Insights from a Quality Improvement Project.

Nwanaji-Enwerem, Jamaji C / Ehrhardt, Tori F / Gordon, Brittney / Meyer, Hannah / Cardell, Annemarie / Selby, Maurice / Wallace, Bradley A / Gittinger, Matthew / Siegelman, Jeffrey N

Healthcare (Basel, Switzerland)

2024 Volume 12, Issue 6

Abstract: Few studies explore emergency medicine (EM) residency shift scheduling software as a mechanism to reduce administrative demands and broader resident burnout. A local needs assessment demonstrated a learning curve for chief resident schedulers and several ...

Abstract	Few studies explore emergency medicine (EM) residency shift scheduling software as a mechanism to reduce administrative demands and broader resident burnout. A local needs assessment demonstrated a learning curve for chief resident schedulers and several areas for improvement. In an institutional quality improvement project, we utilized an external online cross-sectional convenience sampling pilot survey of United States EM residency programs to collect information on manual versus software-based resident shift scheduling practices and associated scheduler and scheduler-perceived resident satisfaction. Our external survey response rate was 19/253 (8%), with all United States regions (i.e., northeast, southeast, midwest, west, and southwest) represented. Two programs (11%) reported manual scheduling without any software. ShiftAdmin was the most popularly reported scheduling software (53%). Although not statistically significant, manual scheduling had the lowest satisfaction score and programs with ≤30 residents reported the highest levels of satisfaction. Our data suggest that improvements in existing software-based technologies are needed. Artificial intelligence technologies may prove useful for reducing administrative scheduling demands and optimizing resident scheduling satisfaction.
Language	English
Publishing date	2024-03-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare12060612
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Article ; Online: Effects of familiar music exposure on deliberate retrieval of remote episodic and semantic memories in healthy aging adults.

Bloom, Paul Alexander / Bartlett, Ella / Kathios, Nicholas / Algharazi, Sameah / Siegelman, Matthew / Shen, Fan / Beresford, Lea / DiMaggio-Potter, Michaelle Evangeline / Singh, Anshita / Bennett, Sarah / Natarajan, Nandhini / Lee, Hannah / Sajid, Sumra / Joyce, Erin / Fischman, Rachel / Hutchinson, Samuel / Pan, Sophie / Tottenham, Nim / Aly, Mariam

Memory (Hove, England)

2023 Volume 31, Issue 3, Page(s) 428–456

Abstract: Familiar music facilitates memory retrieval in adults with dementia. However, mechanisms behind this effect, and its generality, are unclear because of a lack of parallel work in healthy aging. Exposure to familiar music enhances spontaneous recall of ... ...

Abstract	Familiar music facilitates memory retrieval in adults with dementia. However, mechanisms behind this effect, and its generality, are unclear because of a lack of parallel work in healthy aging. Exposure to familiar music enhances spontaneous recall of memories directly cued by the music, but it is unknown whether such effects extend to deliberate recall more generally - e.g., to memories not directly linked to the music being played. It is also unclear whether familiar music boosts recall of specific episodes versus more generalised semantic memories, or whether effects are driven by domain-general mechanisms (e.g., improved mood). In a registered report study, we examined effects of familiar music on deliberate recall in healthy adults ages 65-80 years (
MeSH term(s)	Humans ; Adult ; Aged ; Aged, 80 and over ; Healthy Aging ; Semantics ; Memory, Episodic ; Mental Recall/physiology ; Cues
Language	English
Publishing date	2023-01-18
Publishing country	England
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1147478-6
ISSN	1464-0686 ; 0965-8211
ISSN (online)	1464-0686
ISSN	0965-8211
DOI	10.1080/09658211.2023.2166078
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Article ; Online: Composition is the Core Driver of the Language-selective Network.

Mollica, Francis / Siegelman, Matthew / Diachek, Evgeniia / Piantadosi, Steven T / Mineroff, Zachary / Futrell, Richard / Kean, Hope / Qian, Peng / Fedorenko, Evelina

Neurobiology of language (Cambridge, Mass.)

2020 Volume 1, Issue 1, Page(s) 104–134

Abstract: The frontotemporal language network responds robustly and selectively to sentences. But the features of linguistic input that drive this response and the computations that these language areas support remain debated. Two key features of sentences are ... ...

Abstract	The frontotemporal language network responds robustly and selectively to sentences. But the features of linguistic input that drive this response and the computations that these language areas support remain debated. Two key features of sentences are typically confounded in natural linguistic input: words in sentences (a) are semantically and syntactically combinable into phrase- and clause-level meanings, and (b) occur in an order licensed by the language's grammar. Inspired by recent psycholinguistic work establishing that language processing is robust to word order violations, we hypothesized that the core linguistic computation is composition, and, thus, can take place even when the word order violates the grammatical constraints of the language. This hypothesis predicts that a linguistic string should elicit a sentence-level response in the language network provided that the words in that string can enter into dependency relationships as in typical sentences. We tested this prediction across two fMRI experiments (total
Language	English
Publishing date	2020-03-01
Publishing country	United States
Document type	Journal Article
ISSN	2641-4368
ISSN (online)	2641-4368
DOI	10.1162/nol_a_00005
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Article ; Online: Global patterns of management and governance of small-scale fisheries

Basurto, Xavier / Siegelman, Ben / Navarro, Maria Isabel / del Mar Mancha-Cisneros, Maria / Burgos, Ariadna / Artaud, Hélène / Pauwelussen, Annet / Kraan, Marloes / Toonen, Hilde

Illuminating Hidden Harvests ; ISBN: 9789251376829

contributions to the implementation of the SSF Guideline

2023

Keywords	Life Science
Language	English
Publisher	FAO
Publishing country	nl
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Cooperative carbon capture and steam regeneration with tetraamine-appended metal-organic frameworks.

Kim, Eugene J / Siegelman, Rebecca L / Jiang, Henry Z H / Forse, Alexander C / Lee, Jung-Hoon / Martell, Jeffrey D / Milner, Phillip J / Falkowski, Joseph M / Neaton, Jeffrey B / Reimer, Jeffrey A / Weston, Simon C / Long, Jeffrey R

Science (New York, N.Y.)

2020 Volume 369, Issue 6502, Page(s) 392–396

Abstract: Natural gas has become the dominant source of electricity in the United States, and technologies capable of efficiently removing carbon dioxide ( ... ...

Abstract	Natural gas has become the dominant source of electricity in the United States, and technologies capable of efficiently removing carbon dioxide (CO
Language	English
Publishing date	2020-07-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	128410-1
ISSN	1095-9203 ; 0036-8075
ISSN (online)	1095-9203
ISSN	0036-8075
DOI	10.1126/science.abb3976
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Article ; Online: Cooperative Carbon Dioxide Capture in Diamine-Appended Magnesium-Olsalazine Frameworks.

Zhu, Ziting / Parker, Surya T / Forse, Alexander C / Lee, Jung-Hoon / Siegelman, Rebecca L / Milner, Phillip J / Tsai, Hsinhan / Ye, Mengshan / Xiong, Shuoyan / Paley, Maria V / Uliana, Adam A / Oktawiec, Julia / Dinakar, Bhavish / Didas, Stephanie A / Meihaus, Katie R / Reimer, Jeffrey A / Neaton, Jeffrey B / Long, Jeffrey R

Journal of the American Chemical Society

2023 Volume 145, Issue 31, Page(s) 17151–17163

Abstract: Diamine-appended ... ...

Abstract	Diamine-appended Mg
Language	English
Publishing date	2023-07-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.3c03870
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Article ; Online: MRI Phenotyping of COL9A2/Trp2 and COL9A3/Trp3 Alleles in Lumbar Disc Disease: A Case-control Study in South-Western Iranian Population Reveals a Significant Trp3-Disease Association in Males.

Bagheri, Mohammad H / Honarpisheh, Amir P / Yavarian, Majid / Alavi, Zahra / Siegelman, Jenifer / Valtchinov, Vladimir I

Spine

2016 Volume 41, Issue 21, Page(s) 1661–1667

Abstract: Study design: A case-control study of the Trp2/3 alleles of COL9A2/3 genes and their correlation with occurrence of Lumbar disc disease (DDD) as phenotyped by magnetic resonance imaging.: Objective: To establish a better understanding of relationship ...

Abstract	Study design: A case-control study of the Trp2/3 alleles of COL9A2/3 genes and their correlation with occurrence of Lumbar disc disease (DDD) as phenotyped by magnetic resonance imaging. Objective: To establish a better understanding of relationship between presence of said alleles and occurrence of DDD in South-Western Iranian population. Summary of background data: A number of genetic predisposing factors have been identified in elevating the risk of developing DDD. Specifically, the Trp2 and Trp3 alleles of COL9A2 and COL9A3 genes have been suggested as DDD risk variants. Methods: A total of 108 patients (mean age = 41±11.8 yrs, range = 20-66 yrs) with 57 controls (mean age = 35±10.0 yrs, range = 20-58 yrs) participated in the study. The frequency of G/A polymorphism in COL9A2 gene on location 326 on chromosome 1 and G/A/C/ or T polymorphism in 103 location of COL9A3 gene on chromosome 20 was assessed using a PCR short-primer technique. Outcome measure was defined as presence of DDD on MRI. Odds ratios (OR) and 95% confidence intervals (CI) were used to assess the likelihood of DDD given occurrence of Trp2(3). Results: Each allele was present in both patients and controls. The Trp2 allele was positive in 28.5% of individuals (31.5% of patients; 22.8% of controls), OR 1.55 (0.71-3.56). The Trp3 allele, the frequency was 23.6% in all patients (26.9% patients; 17.5% controls), OR 1.72 (0.73-4.33). We observed a 5.8-fold increase in the odds of DDD in males when the Trp3 allele was present, OR 5.83 (1.09-9.98), P = 0.0273. Conclusion: Both Trp2 and Trp3 alleles occurred more frequently compared with other studied ethnicities. The sampled Iranian population exhibited a similar Trp2 frequency to a Southern Chinese population, and Trp3 occurrence to Finnish and Greek population. We found that male patient were much more likely to develop DDD when Trp 3 was present. Level of evidence: N/A.
MeSH term(s)	Adult ; Aged ; Alleles ; Asian Continental Ancestry Group ; Case-Control Studies ; Collagen Type IX/genetics ; European Continental Ancestry Group ; Female ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Intervertebral Disc/diagnostic imaging ; Intervertebral Disc Degeneration/diagnostic imaging ; Intervertebral Disc Degeneration/genetics ; Iran ; Lumbar Vertebrae/diagnostic imaging ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Phenotype ; Polymorphism, Single Nucleotide ; Sex Factors ; Young Adult
Chemical Substances	COL9A2 protein, human ; COL9A3 protein, human ; Collagen Type IX
Language	English
Publishing date	2016-10-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	752024-4
ISSN	1528-1159 ; 0362-2436
ISSN (online)	1528-1159
ISSN	0362-2436
DOI	10.1097/BRS.0000000000001617
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Article ; Online: MRI Phenotyping of COL9A2/Trp2 and COL9A3/Trp3 Alleles in Degenerative Disc Disease: a Case-Control Study in Southwestern Iranian Population Reveals a Significant Trp3-Disease Association in Males.

Bagheri, Mohammad H / Honarpisheh, Amir P / Yavarian, Majid / Alavi, Zahra / Siegelman, Jenifer / Valtchinov, Vladimir I

Spine

2016

Abstract: Study design: A case-control study of the Trp2(3) alleles of COL9A2(3) genes and their correlation with occurrence of Degenerative Disc Disease (DDD), as phenotyped by magnetic resonance (MR) imaging.: Objective: To establish a better understanding ... ...

Abstract	Study design: A case-control study of the Trp2(3) alleles of COL9A2(3) genes and their correlation with occurrence of Degenerative Disc Disease (DDD), as phenotyped by magnetic resonance (MR) imaging. Objective: To establish a better understanding of relationship between presence of said alleles and occurrence of DDD in Southwestern Iranian population. Summary of background data: A number of genetic pre-disposing factors have been identified in elevating the risk of developing DDD. Specifically, the Trp2 and Trp3 alleles of COL9A2 and COL9A3 genes have been suggested as DDD risk variants. Methods: 108 cases (mean age = 41±11.8, range = 20 to 66) with 57 controls (mean age = 35±10.0, range = 20 to 58) participated in the study. The frequency of G/A polymorphism in COL9A2 gene on location 326 on chromosome 1 and G/A/C/ or T polymorphism in 103 location of COL9A3 gene on chromosome 20 was assessed using a PCR short-primer technique. Outcome measure was defined as presence of DDD on MRI. Odds Ratios (OR) and 95% Confidence Intervals were used to assess the likelihood of DDD given occurrence of Trp2(3). Results: Each allele was present in both cases and controls. The Trp2 allele was positive in 28.5% of individuals (31.5% of cases; 22.8% of controls), OR 1.55 (0.71-3.56). The Trp3 allele, the frequency was 23.6% in all patients (26.9% cases; 17.5% controls), OR 1.72 (0.73-4.33). We observed a 5.8-fold increase in the odds of DDD in males when the Trp3 allele was present, OR 5.83 (1.09-9.98), p-value = 0.0273. Conclusions: Both Trp2 and Trp3 alleles occurred more frequently compared to other studied ethnicities. The sampled Iranian population exhibited a similar Trp2 frequency to a Southern Chinese population, and Trp3 occurrence to Finnish and Greek population. We found that male patient were much more likely to develop DDD when Trp 3 was present. Level of evidence: N/A.
Language	English
Publishing date	2016-04-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	752024-4
ISSN	1528-1159 ; 0362-2436
ISSN (online)	1528-1159
ISSN	0362-2436
DOI	10.1097/BRS.0000000000001617
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Article ; Online: Multiparametric magnetic resonance imaging/magnetic resonance elastography assesses progression and regression of steatosis, inflammation, and fibrosis in alcohol-associated liver disease.

Chen, Jingbiao / Martin-Mateos, Rosa / Li, Jiahui / Yin, Ziying / Chen, Jie / Lu, Xin / Glaser, Kevin J / Mounajjed, Taofic / Yashiro, Hiroaki / Siegelman, Jenifer / Winkelmann, Christopher T / Wang, Jin / Ehman, Richard L / Shah, Vijay H / Yin, Meng

Alcoholism, clinical and experimental research

2021 Volume 45, Issue 10, Page(s) 2103–2117

Abstract: Background: Magnetic resonance imaging (MRI) and MRI-based elastography (MRE) are the most promising noninvasive techniques in assessing liver diseases. The purpose of this study was to evaluate an advanced multiparametric imaging method for staging ... ...

Abstract	Background: Magnetic resonance imaging (MRI) and MRI-based elastography (MRE) are the most promising noninvasive techniques in assessing liver diseases. The purpose of this study was to evaluate an advanced multiparametric imaging method for staging disease and assessing treatment response in realistic preclinical alcohol-associated liver disease (ALD). Methods: We utilized four different preclinical mouse models in our study: Model 1-mice were fed a fast-food diet and fructose water for 48 weeks to induce nonalcoholic fatty liver disease; Model 2-mice were fed chronic-binge ethanol (EtOH) for 10 days or 8 weeks to induce liver steatosis/inflammation. Two groups of mice were treated with interleukin-22 at different time points to induce disease regression; Model 3-mice were administered CCl Results: Multiparametric models with combinations of biomarkers (LS, LM, DR, and PDFF) used noninvasively to predict the histologic severity and regression of steatosis, inflammation, and fibrosis were highly accurate (area under the curve > 0.84 for all). A three-parameter model that incorporates LS, DR, and ALT predicted histologic fibrosis progression (r = 0.84, p < 0.0001) and regression (r = 0.79, p < 0.0001) as measured by collagen content in livers. Conclusion: This preclinical study provides evidence that multiparametric MRI/MRE can be used noninvasively to assess disease severity and monitor treatment response in ALD.
MeSH term(s)	Animals ; Carbon Tetrachloride/administration & dosage ; Collagen/analysis ; Disease Models, Animal ; Disease Progression ; Elasticity Imaging Techniques/methods ; Ethanol/administration & dosage ; Fatty Liver, Alcoholic/diagnostic imaging ; Female ; Hepatitis, Alcoholic/diagnostic imaging ; Interleukins/administration & dosage ; Liver/chemistry ; Liver Cirrhosis/diagnostic imaging ; Liver Diseases, Alcoholic/diagnostic imaging ; Male ; Mice ; Mice, Inbred C57BL ; Multiparametric Magnetic Resonance Imaging/methods ; Non-alcoholic Fatty Liver Disease/diagnostic imaging ; Sensitivity and Specificity ; Interleukin-22
Chemical Substances	Interleukins ; Ethanol (3K9958V90M) ; Collagen (9007-34-5) ; Carbon Tetrachloride (CL2T97X0V0)
Language	English
Publishing date	2021-09-05
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	428999-7
ISSN	1530-0277 ; 0145-6008
ISSN (online)	1530-0277
ISSN	0145-6008
DOI	10.1111/acer.14699
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Article ; Online: Probabilistic atlas for the language network based on precision fMRI data from >800 individuals.

Scientific data

2022 Volume 9, Issue 1, Page(s) 529

Abstract: Two analytic traditions characterize fMRI language research. One relies on averaging activations across individuals. This approach has limitations: because of inter-individual variability in the locations of language areas, any given voxel/vertex in a ... ...

Abstract	Two analytic traditions characterize fMRI language research. One relies on averaging activations across individuals. This approach has limitations: because of inter-individual variability in the locations of language areas, any given voxel/vertex in a common brain space is part of the language network in some individuals but in others, may belong to a distinct network. An alternative approach relies on identifying language areas in each individual using a functional 'localizer'. Because of its greater sensitivity, functional resolution, and interpretability, functional localization is gaining popularity, but it is not always feasible, and cannot be applied retroactively to past studies. To bridge these disjoint approaches, we created a probabilistic functional atlas using fMRI data for an extensively validated language localizer in 806 individuals. This atlas enables estimating the probability that any given location in a common space belongs to the language network, and thus can help interpret group-level activation peaks and lesion locations, or select voxels/electrodes for analysis. More meaningful comparisons of findings across studies should increase robustness and replicability in language research.
MeSH term(s)	Brain/diagnostic imaging ; Brain/physiology ; Brain Mapping ; Humans ; Language ; Magnetic Resonance Imaging
Language	English
Publishing date	2022-08-29
Publishing country	England
Document type	Dataset ; Journal Article
ZDB-ID	2775191-0
ISSN	2052-4463 ; 2052-4463
ISSN (online)	2052-4463
ISSN	2052-4463
DOI	10.1038/s41597-022-01645-3
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