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  1. Article ; Online: Response to McMahon et al's "Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of four hundred fourteen cases".

    Poulas, Konstantinos / Farsalinos, Konstantinos

    Journal of the American Academy of Dermatology

    2021  Volume 86, Issue 4, Page(s) e163–e164

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; Registries ; SARS-CoV-2 ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-11-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2021.09.071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1540: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Article: The impact of COVID-19 lockdown on children's and adolescents' mental health in Greece.

    Magklara, Konstantina / Lazaratou, Helen / Barbouni, Anastasia / Poulas, Konstantinos / Farsalinos, Konstantinos

    Children & society

    2022  

    Abstract: The aim of the study was to investigate the impact of the COVID-19 lockdown on children's and adolescents' mental health in Greece during the lockdown of spring 2020. A cross-sectional survey of 1232 Greek parents was conducted in spring 2020. 35.1% of ... ...

    Abstract The aim of the study was to investigate the impact of the COVID-19 lockdown on children's and adolescents' mental health in Greece during the lockdown of spring 2020. A cross-sectional survey of 1232 Greek parents was conducted in spring 2020. 35.1% of parents reported that their children's psychological health was significantly affected. Parental unemployment, limited opportunity for tele-work and deteriorating psychological health, increased family conflicts and children's pre-existing physical health conditions were all significantly associated with mental health impact. Children and adolescents may experience adverse mental health effects due to the COVID-19 pandemic.
    Language English
    Publishing date 2022-07-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001233-0
    ISSN 1099-0860 ; 0951-0605
    ISSN (online) 1099-0860
    ISSN 0951-0605
    DOI 10.1111/chso.12605
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  3. Article ; Online: Patterns of flavored e-cigarette use among adult vapers in the USA: an online cross-sectional survey of 69,233 participants.

    Farsalinos, Konstantinos / Russell, Christopher / Polosa, Riccardo / Poulas, Konstantinos / Lagoumintzis, George / Barbouni, Anastasia

    Harm reduction journal

    2023  Volume 20, Issue 1, Page(s) 147

    Abstract: Background: Flavored e-cigarettes remain a controversial topic with regulators planning or already implementing restrictions worldwide. In this study, we examined patterns of flavor use in e-cigarettes among a convenience sample of US adult vapers.: ... ...

    Abstract Background: Flavored e-cigarettes remain a controversial topic with regulators planning or already implementing restrictions worldwide. In this study, we examined patterns of flavor use in e-cigarettes among a convenience sample of US adult vapers.
    Methods: Participants aged ≥ 18 years who reported ever using an e-cigarette were included in the study (N = 69,233) and responded to an online questionnaire. Their smoking status was recorded as well as patterns of flavor use at e-cigarette use initiation, at the time of the survey and at the time of smoking cessation (for participants who used to smoke and were using e-cigarettes at the time of quitting).
    Results: The most popular flavors at e-cigarette use initiation were fruit (82.8%), followed by dessert/pastry/bakery (68.6%) and candy/chocolate/sweet (52.2%). Slightly higher prevalence of using fruit and dessert/pastry/bakery flavors was observed in those who never smoked compared to those who were currently and formerly smoking. Tobacco flavors were used by 20.8% of the participants and was by far the least prevalent among participants who never smoked. Similar patterns were observed with participants' choices at the time of the survey, but tobacco flavor use was substantially reduced (7.7%). Only 2.1% reported tobacco as the single most often used flavor. The most prevalent flavor at the time of quitting smoking was again fruit (83.3%), followed by dessert/pastry/bakery (68.0%) and candy/chocolate/sweet (44.5%). These flavors were considered the most helpful for quitting smoking. Tobacco flavor use at the time of smoking cessation was reported by 15.0%, while 9.3% considered it helpful for quitting smoking.
    Conclusion: Non-tobacco flavors were popular among the US adult vapers who participated in the study, and were popular choices at the time of quitting smoking for those who formerly smoked. Tobacco flavor use prevalence was low and was further reduced over time. Regulators should consider the flavor choice of adult consumers, especially those who quit smoking, when preparing legislation on flavored e-cigarettes.
    MeSH term(s) Adult ; Humans ; United States/epidemiology ; Smokers ; Electronic Nicotine Delivery Systems ; Cross-Sectional Studies ; Vaping/epidemiology ; Flavoring Agents ; Tobacco Products
    Chemical Substances Flavoring Agents
    Language English
    Publishing date 2023-10-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2146691-9
    ISSN 1477-7517 ; 1477-7517
    ISSN (online) 1477-7517
    ISSN 1477-7517
    DOI 10.1186/s12954-023-00876-w
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  4. Article ; Online: Is SARS-CoV-2 Spike glycoprotein impairing macrophage function via α7-nicotinic acetylcholine receptors?

    Tanmay, Saraiya / Labrou, Dimitrios / Farsalinos, Konstantinos / Poulas, Konstantinos

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

    2021  Volume 152, Page(s) 112184

    Abstract: The innate immune cells play an important role in handling early infections, and can eliminate them completely up to a certain threshold. Beyond that threshold they take up their role in "The Resolution of Inflammation". The recognition of the SARS-CoV-2 ...

    Abstract The innate immune cells play an important role in handling early infections, and can eliminate them completely up to a certain threshold. Beyond that threshold they take up their role in "The Resolution of Inflammation". The recognition of the SARS-CoV-2 antigen triggers an eicosanoid storm and initiates a robust inflammatory response. This establishes a positive feedback loop which develops into a sustained cytokine storm which interferes with the activation of adaptive immune cells. The mechanism of this interaction, and hence the pathogenesis of the virus with the immune system, is yet to be determined. In silico studies predict a direct SARS-CoV-2 spike glycoprotein interaction with nicotinic acetylcholine receptors, which could impair macrophage function and initiate the cascade of events in severe infections. We here, add to the hypothesis that immune dysregulation can be caused by the interaction of the SARS-CoV-2 spike glycoprotein via a cryptic epitope with the α7-nAChR in Type-1 macrophages, discuss its implications for the treatment of COVID-19 patients, and present better prospects for the design and dissemination of more effective vaccines and their importance.
    MeSH term(s) COVID-19/immunology ; Epitopes ; Humans ; Macrophages/virology ; Spike Glycoprotein, Coronavirus/immunology ; alpha7 Nicotinic Acetylcholine Receptor/immunology
    Chemical Substances Epitopes ; Spike Glycoprotein, Coronavirus ; alpha7 Nicotinic Acetylcholine Receptor ; spike protein, SARS-CoV-2
    Language English
    Publishing date 2021-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2021.112184
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 529: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: COVID-19 and the nicotinic cholinergic system.

    Farsalinos, Konstantinos / Angelopoulou, Athina / Alexandris, Nikos / Poulas, Konstantinos

    The European respiratory journal

    2020  Volume 56, Issue 1

    MeSH term(s) Betacoronavirus ; COVID-19 ; Cholinergic Agents ; Coronavirus Infections ; Humans ; Nicotine ; Pandemics ; Pneumonia, Viral ; Pulmonary Disease, Chronic Obstructive ; SARS-CoV-2 ; Smokers
    Chemical Substances Cholinergic Agents ; Nicotine (6M3C89ZY6R)
    Keywords covid19
    Language English
    Publishing date 2020-07-16
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01589-2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2322: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 292: Show issues

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  6. Article ; Online: Activation of TLR7 and Innate Immunity as an Efficient Method Against COVID-19 Pandemic: Imiquimod as a Potential Therapy.

    Poulas, Konstantinos / Farsalinos, Konstantinos / Zanidis, Charilaos

    Frontiers in immunology

    2020  Volume 11, Page(s) 1373

    MeSH term(s) Adjuvants, Immunologic/therapeutic use ; Betacoronavirus/drug effects ; Betacoronavirus/immunology ; Coronavirus Infections/drug therapy ; Coronavirus Infections/immunology ; Coronavirus Infections/prevention & control ; Drug Repositioning/methods ; Humans ; Imiquimod/therapeutic use ; Immunity, Innate/drug effects ; Pandemics/prevention & control ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/immunology ; Pneumonia, Viral/prevention & control ; Toll-Like Receptor 7/immunology
    Chemical Substances Adjuvants, Immunologic ; TLR7 protein, human ; Toll-Like Receptor 7 ; Imiquimod (P1QW714R7M)
    Keywords covid19
    Language English
    Publishing date 2020-06-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2020.01373
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  7. Article ; Online: First Record of Beauveria varroae , Cordyceps blackwelliae , and Purpureocillium lavendulum from Greece and Their Pathogenicity against Thaumetopoea pityocampa

    Ioannis Lagogiannis / Spiridon Mantzoukas / Panagiotis A. Eliopoulos / Konstantinos Poulas

    Diversity, Vol 15, Iss 312, p

    2023  Volume 312

    Abstract: Entomopathogenic fungi (EPF) consist of a wide range of fungi that can be used as pest control agents, endophytes, and plant growth promoters. In this study of EPF in suburban soils from Achaia, Greece, we used adult beetles as baits for trapping fungal ... ...

    Abstract Entomopathogenic fungi (EPF) consist of a wide range of fungi that can be used as pest control agents, endophytes, and plant growth promoters. In this study of EPF in suburban soils from Achaia, Greece, we used adult beetles as baits for trapping fungal isolates. According to the macroscopic and microscopic traits of the collected isolates, three species corresponded to Beauveria varroae Vuill. (Hypocreales: Cordycipitaceae); Purpureocillium lavendulum Perdomo, Gené, Cano & Guarro (Hypocreales: Ophiocordycipitaceae); and Cordyceps blackwelliae Mongkolsamrit, Noisripoom, Thanakitpipattana, Spatafora & Luangsaard (Hypocreales: Claviceptaceae). Their taxonomic identity was established by ITS-rDNA sequence amplification and sequencing, molecular database comparisons, and phylogenetic analysis. The application of these new EPF species clearly demonstrated remarkable insecticidal action on Thaumetopoea pityocampa (Lepidoptera, Notodontidae) larvae, which increased with the application dose. Our findings are important based on the enhancement of the application of new EPF species as biocontrol agents within the framework of eco-friendly pest management.
    Keywords entomopathogenic fungi ; Beauveria varroae ; Purpureocillium lavendulum ; Cordyceps blackwelliae ; Thaumetopoea pityocampa ; Greece ; Biology (General) ; QH301-705.5
    Subject code 580
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Activation of TLR7 and Innate Immunity as an Efficient Method Against COVID-19 Pandemic

    Konstantinos Poulas / Konstantinos Farsalinos / Charilaos Zanidis

    Frontiers in Immunology, Vol

    Imiquimod as a Potential Therapy

    2020  Volume 11

    Keywords Imiquimod (IMQ) ; innate immunity ; COVID-19 ; SARS - CoV-2 ; immune activation ; Immunologic diseases. Allergy ; RC581-607 ; covid19
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Activation of TLR7 and Innate Immunity as an Efficient Method Against COVID-19 Pandemic

    Poulas, Konstantinos / Farsalinos, Konstantinos / Zanidis, Charilaos

    Frontiers in Immunology

    Imiquimod as a Potential Therapy

    2020  Volume 11

    Keywords covid19
    Publisher Frontiers Media SA
    Publishing country ch
    Document type Article ; Online
    ZDB-ID 2606827-8
    ISSN 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2020.01373
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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