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  1. Book: Sex, gender, and respiratory health and disease

    Glassberg, Marilyn K.

    (Clinics in chest medicine ; 25,2)

    2004  

    Author's details guest ed. Marilyn K. Glassberg
    Series title Clinics in chest medicine ; 25,2
    Collection
    Language English
    Size XIV S., S. 237 - 407 : graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT014052813
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Overview of idiopathic pulmonary fibrosis, evidence-based guidelines, and recent developments in the treatment landscape.

    Glassberg, Marilyn K

    The American journal of managed care

    2019  Volume 25, Issue 11 Suppl, Page(s) S195–S203

    Abstract: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive-fibrosing interstitial lung disease of unknown origin that affects 3 million people worldwide and imparts substantial burdens to patients, their families, and the healthcare system. The IPF ... ...

    Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive-fibrosing interstitial lung disease of unknown origin that affects 3 million people worldwide and imparts substantial burdens to patients, their families, and the healthcare system. The IPF disease course is highly variable and presents several diagnostic and management-related challenges. Two therapies, nintedanib and pirfenidone, are FDA approved and are recommended by clinical practice guidelines for the treatment of IPF. Although neither of these treatments is curative, both slow disease progression and impact survival of patients with IPF. To ensure optimal management, this supplement will provide an overview of the epidemiology, pathophysiology, and diagnosis of IPF, along with management-based considerations including evidence-based guideline recommendations, in-depth reviews of nintedanib and pirfenidone, and outcomes from other completed clinical trials.
    MeSH term(s) Age Distribution ; Aging/physiology ; Antineoplastic Agents/economics ; Antineoplastic Agents/therapeutic use ; Chronic Disease ; Comorbidity ; Disease Progression ; Health Expenditures ; Humans ; Idiopathic Pulmonary Fibrosis/diagnosis ; Idiopathic Pulmonary Fibrosis/drug therapy ; Idiopathic Pulmonary Fibrosis/epidemiology ; Idiopathic Pulmonary Fibrosis/physiopathology ; Indoles/adverse effects ; Indoles/economics ; Indoles/therapeutic use ; Patient Education as Topic ; Practice Guidelines as Topic ; Pyridones/adverse effects ; Pyridones/economics ; Pyridones/therapeutic use ; Sex Distribution
    Chemical Substances Antineoplastic Agents ; Indoles ; Pyridones ; pirfenidone (D7NLD2JX7U) ; nintedanib (G6HRD2P839)
    Language English
    Publishing date 2019-08-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2035781-3
    ISSN 1936-2692 ; 1088-0224 ; 1096-1860
    ISSN (online) 1936-2692
    ISSN 1088-0224 ; 1096-1860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Multipotent Mesenchymal Stromal Cells and Lung Disease: Not Ready for Prime Time.

    Purdon, Stefanie / Glassberg, Marilyn K

    Annals of the American Thoracic Society

    2019  Volume 16, Issue 6, Page(s) 669–671

    MeSH term(s) Clinical Trials as Topic ; Humans ; Lung Diseases/therapy ; Mesenchymal Stem Cell Transplantation ; Mesenchymal Stem Cells/cytology ; Pluripotent Stem Cells/cytology
    Language English
    Publishing date 2019-02-18
    Publishing country United States
    Document type Editorial
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.201811-843PS
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: To be or not to be a neoplasm: what is lymphangioleiomyomatosis? Are we calling it what it really is?

    Glassberg, Marilyn K

    American journal of respiratory and critical care medicine

    2013  Volume 188, Issue 3, Page(s) 397–398

    MeSH term(s) Cell Transformation, Neoplastic/pathology ; Female ; Humans ; Lung Neoplasms/pathology ; Lymphangioleiomyomatosis/classification ; Lymphangioleiomyomatosis/pathology
    Language English
    Publishing date 2013-08-01
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201210-1912LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Corrigendum: Antifibrotics in COVID-19 Lung Disease: Let Us Stay Focused.

    Chaudhary, Sachin / Natt, Bhupinder / Bime, Christian / Knox, Kenneth S / Glassberg, Marilyn K

    Frontiers in medicine

    2021  Volume 7, Page(s) 604640

    Abstract: This corrects the article DOI: 10.3389/fmed.2020.00539.]. ...

    Abstract [This corrects the article DOI: 10.3389/fmed.2020.00539.].
    Language English
    Publishing date 2021-03-11
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2020.604640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Stem Cell Therapy for COPD: Hope and Exploitation.

    Glassberg, Marilyn K / Csete, Isabelle / Simonet, Emmanuelle / Elliot, Sharon J

    Chest

    2021  Volume 160, Issue 4, Page(s) 1271–1281

    Abstract: COPD is a chronic inflammatory and destructive disease characterized by progressive decline in lung function that can accelerate with aging. Preclinical studies suggest that mesenchymal stem cells (MSCs) may provide a therapeutic option for this ... ...

    Abstract COPD is a chronic inflammatory and destructive disease characterized by progressive decline in lung function that can accelerate with aging. Preclinical studies suggest that mesenchymal stem cells (MSCs) may provide a therapeutic option for this incurable disease because of their antiinflammatory, reparative, and immunomodulatory properties. To date, clinical trials using MSCs demonstrate safety in patients with COPD. However, because of the notable absence of large, multicenter randomized trials, no efficacy or evidence exists to support the possibility that MSCs can restore lung function in patients with COPD. Unfortunately, the investigational status of cell-based interventions for lung diseases has not hindered the propagation of commercial businesses, exploitation of the public, and explosion of medical tourism to promote unproven and potentially harmful cell-based interventions for COPD in the United States and worldwide. Patients with COPD constitute the largest group of patients with lung disease flocking to these unregulated clinics. This review highlights the numerous questions and concerns that remain before the establishment of cell-based interventions as safe and efficacious treatments for patients with COPD.
    MeSH term(s) Animals ; Cell- and Tissue-Based Therapy ; Clinical Trials as Topic ; Evidence-Based Medicine ; Extracellular Vesicles ; Fraud ; Humans ; Mesenchymal Stem Cell Transplantation ; Pulmonary Disease, Chronic Obstructive/therapy ; Registries
    Language English
    Publishing date 2021-04-21
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.04.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Sex and Gender in Lung Disease and Sleep Disorders: A State-of-the-Art Review.

    Sodhi, Amik / Pisani, Margaret / Glassberg, Marilyn K / Bourjeily, Ghada / D'Ambrosio, Carolyn

    Chest

    2022  Volume 162, Issue 3, Page(s) 647–658

    Abstract: The terms sex and gender often are used interchangeably, but have specific meaning when it comes to their effects on lung disease. Ample evidence is now available that sex and gender affect the incidence, susceptibility, presentation, diagnosis, and ... ...

    Abstract The terms sex and gender often are used interchangeably, but have specific meaning when it comes to their effects on lung disease. Ample evidence is now available that sex and gender affect the incidence, susceptibility, presentation, diagnosis, and severity of many lung diseases. Some conditions are more prevalent in women, such as asthma. Other conditions are seen almost exclusively in women, like lymphangioleiomyomatosis. Some life stages-such as pregnancy-are unique to women and can affect the onset and course of lung disease. Clinical presentation may differ as well, such as higher number of exacerbations experienced by women with COPD and greater cardiovascular morbidity in women with sleep-disordered breathing. In addition, response to therapy and medication safety may also differ by sex, and yet, pharmacogenomic factors often are not addressed adequately in clinical trials. Various aspects of lung and sleep biology and pathobiology are impacted by female sex and female reproductive transitions. Differential gene expression or organ development can be impacted by these biological differences. Understanding these differences is the first step in moving toward precision medicine for women. This article is a state-of-the-art review of specific effects of sex and gender focused on epidemiology, disease presentation, risk factors, and management of lung diseases. Pathobiological mechanisms explaining sex differences in these diseases are beyond the scope of this article. We review the literature and focus on recent guidelines about using sex and gender in research. We also review sex and gender differences in lung diseases.
    MeSH term(s) Asthma ; Female ; Humans ; Lung ; Lung Diseases/epidemiology ; Male ; Pregnancy ; Sex Factors ; Sleep Apnea Syndromes/epidemiology ; Sleep Wake Disorders/epidemiology
    Language English
    Publishing date 2022-03-14
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2022.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Response.

    Glassberg, Marilyn K / Khan, Aisha / Hare, Joshua M

    Chest

    2018  Volume 153, Issue 1, Page(s) 287–288

    MeSH term(s) Humans ; Idiopathic Pulmonary Fibrosis ; Mesenchymal Stem Cells
    Language English
    Publishing date 2018-01-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2017.10.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Trends in Idiopathic Pulmonary Fibrosis-related Mortality in the United States: 2000-2017.

    Dove, Erik P / Olson, Amy L / Glassberg, Marilyn K

    American journal of respiratory and critical care medicine

    2019  Volume 200, Issue 7, Page(s) 929–931

    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Idiopathic Pulmonary Fibrosis/epidemiology ; Idiopathic Pulmonary Fibrosis/mortality ; Incidence ; Male ; Middle Aged ; Mortality/trends ; United States/epidemiology
    Language English
    Publishing date 2019-06-21
    Publishing country United States
    Document type Letter
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201905-0958LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Arizona Surge Line: An emergent statewide COVID-19 transfer service with equity as an outcome.

    Villarroel, Lisa / Tams, Erin / Smith, Luke / Rigler, Jessica / Wilson, Dena / Hu, Chengcheng / Glassberg, Marilyn K

    Frontiers in public health

    2023  Volume 10, Page(s) 1028353

    Abstract: Introduction: The Arizona Surge Line was an emergent initiative during the COVID-19 pandemic to facilitate COVID-19 patient transfers and load-level hospitals on a statewide level. It was designed and implemented by the Arizona Department of Health ... ...

    Abstract Introduction: The Arizona Surge Line was an emergent initiative during the COVID-19 pandemic to facilitate COVID-19 patient transfers and load-level hospitals on a statewide level. It was designed and implemented by the Arizona Department of Health Services in preparation for the first hospital surge due to COVID-19, recognizing the disproportionate impact that hospital surge would have on rural and tribal populations.
    Methods: We analyzed the Arizona Surge Line transfer data for the state's first two COVID-19 surges (4/16/2020-3/6/2021). Transfer data included transfer request characteristics, patient demographics and participating hospital characteristics. When applicable, we compared this data with Arizona census data, COVID-19 case data, and the CDC/ATSDR Social Vulnerability Index. The primary outcomes studied were the proportion of COVID-19 patient requests being successfully transferred, the median transfer time, and the proportion of vulnerable populations impacted.
    Results: During the period of study, 160 hospitals in Arizona made 6,732 requests for transfer of COVID-19 patients. The majority of these patients (84%, 95% CI: 83-85%) were placed successfully with a median transfer time of 59 min (inter-quartile range 33-116). Of all transfer requests, 58% originated from rural hospitals, 53% were for patients of American Indian/Alaska Native ethnicity, and 73% of patients originated from highly vulnerable areas. The majority (98%) of receiving facilities were in urban areas. The Arizona Surge Line matched the number of transfers with licensed market shares during the period of study.
    Conclusions: The Arizona Surge Line is an equity-enhancing initiative that disproportionately benefited vulnerable populations. This statewide transfer infrastructure could become a standard public health mechanism to manage hospital surges and enhance access to care during a health emergency.
    MeSH term(s) Humans ; United States ; Arizona/epidemiology ; COVID-19/epidemiology ; Pandemics
    Language English
    Publishing date 2023-01-25
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.1028353
    Database MEDical Literature Analysis and Retrieval System OnLINE

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