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Article ; Online: Effect of acupuncture on capillary refill time in healthy adults: A clinical study.

Yeh, Bo-Yan / Chao, Yen-Lin / Chen, Yu-Sheng / Yu, Huang-Ping

2021 Volume 135, Page(s) 104135

Abstract: Background: Pulse examination, which reveals information about bodily qi and blood circulation, is an essential diagnostic tool in traditional Chinese medicine. Capillary refill time (CRT) is a simple test parameter for assessing circulation status. ... ...

Abstract	Background: Pulse examination, which reveals information about bodily qi and blood circulation, is an essential diagnostic tool in traditional Chinese medicine. Capillary refill time (CRT) is a simple test parameter for assessing circulation status. Examining the root of pulse and measuring CRT are extremely similar procedures. The objective of this study was to evaluate the effect of acupuncture on CRT. Methods: Three acupoints were selected to evaluate the effects of CRT. CRT, quantitative CRT, heart rate, core body temperature, and blood pressure were measured before acupuncture and immediately after removal of needles and 30 min after removal of needles. A total of 15 healthy adults representing both sexes were prospectively included in the study. The acupoints selected were bilateral Taixi (KI3), Hegu (LI4), and Zusanli (ST36). Each participant received acupuncture three times, interventions were separated by at least 2 days, and acupuncture was performed on only one acupoint at each intervention. Results: CRT decreased significantly after acupuncture on only KI3. Quantitative CRT decreased significantly after acupuncture on KI3 and LI4. Heart rate changed significantly after acupuncture on KI3 and ST36. Conclusion: Acupuncture on KI3 can reduce CRT in health adults.
MeSH term(s)	Acupuncture Points ; Acupuncture Therapy ; Adult ; Blood Flow Velocity ; Capillaries/physiology ; Female ; Humans ; Laser-Doppler Flowmetry ; Male ; Microcirculation ; Middle Aged ; Prospective Studies ; Time Factors
Language	English
Publishing date	2021-01-13
Publishing country	United States
Document type	Clinical Study ; Comparative Study ; Journal Article
ZDB-ID	80307-8
ISSN	1095-9319 ; 0026-2862
ISSN (online)	1095-9319
ISSN	0026-2862
DOI	10.1016/j.mvr.2021.104135
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Acupuncture helps to regain the consciousness of a COVID-19 patient complicated with hypoxic-ischemic encephalopathy: a case report.

Yeh, Bo-Yan / Chen, Yen-Lung / Chang, Shih-An / Lee, Chung-Shu / Chen, Yu-Sheng

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

2021 Volume 42, Issue 2, Page(s) 475–478

MeSH term(s)	Acupuncture Therapy/methods ; Aged ; COVID-19/complications ; Heart Arrest/virology ; Humans ; Hypoxia-Ischemia, Brain/etiology ; Hypoxia-Ischemia, Brain/therapy ; Male ; SARS-CoV-2
Language	English
Publishing date	2021-01-07
Publishing country	Italy
Document type	Case Reports ; Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	2016546-8
ISSN	1590-3478 ; 1590-1874
ISSN (online)	1590-3478
ISSN	1590-1874
DOI	10.1007/s10072-020-04980-8
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Article ; Online: Smart near infrared-responsive nanocomposite hydrogels for therapeutics and diagnostics.

Shen, Ke-Han / Lu, Cheng-Hsun / Kuo, Chih-Yu / Li, Bo-Yan / Yeh, Yi-Cheun

Journal of materials chemistry. B

2021 Volume 9, Issue 35, Page(s) 7100–7116

Abstract: Nanocomposite (NC) hydrogels are emerging biomaterials that possess desirable and defined properties and functions for therapeutics and diagnostics. Particularly, nanoparticles (NPs) are employed as stimulus-transducers in NC hydrogels to facilitate the ... ...

Abstract	Nanocomposite (NC) hydrogels are emerging biomaterials that possess desirable and defined properties and functions for therapeutics and diagnostics. Particularly, nanoparticles (NPs) are employed as stimulus-transducers in NC hydrogels to facilitate the treatment process by providing controllable structural change and payload release under internal and external simulations. Among the various external stimuli, near-infrared (NIR) light has attracted considerable interest due to its minimal photo-damage, deep tissue penetration, low auto-fluorescence in living systems, facile on/off switch, easy remote and spatiotemporal control. In this study, we discuss four types of transducing nanomaterials used in NIR-responsive NC hydrogels, including metal-based nanoparticles, carbon-based nanomaterials, polydopamine nanoparticles (PDA NPs), and upconversion nanoparticles (UCNPs). This review provides an overview of the current progress in NIR-responsive NC hydrogels, focusing on their preparation, properties, applications, and future prospects.
MeSH term(s)	Biocompatible Materials/chemical synthesis ; Biocompatible Materials/chemistry ; Biocompatible Materials/therapeutic use ; Hydrogels/chemical synthesis ; Hydrogels/chemistry ; Hydrogels/therapeutic use ; Infrared Rays ; Materials Testing ; Nanocomposites/chemistry ; Nanocomposites/therapeutic use
Chemical Substances	Biocompatible Materials ; Hydrogels
Language	English
Publishing date	2021-09-15
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2702241-9
ISSN	2050-7518 ; 2050-750X
ISSN (online)	2050-7518
ISSN	2050-750X
DOI	10.1039/d1tb00980j
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Intentional Fallers with Complex Pelvic and Acetabular Fractures Do Not Have worse Radiological and Functional Outcomes than Accidental Fallers

Yi-Hsun Yu / Ying-Chao Chou / Bo-Yan Yeh / Yung-Heng Hsu / I-Jung Chen / Lien-Chung Wei

BioMed Research International, Vol

2022 Volume 2022

Abstract: Individuals who fall from heights of ≥6 m can suffer from complex pelvic and acetabular fractures. The extent to which an intentional fall correlates with prognosis and outcome after osteosynthesis is unclear. Therefore, we aimed to investigate the ... ...

Abstract	Individuals who fall from heights of ≥6 m can suffer from complex pelvic and acetabular fractures. The extent to which an intentional fall correlates with prognosis and outcome after osteosynthesis is unclear. Therefore, we aimed to investigate the clinical outcomes of fallers with pelvic and acetabular fractures after osteosynthesis and compare the radiological and functional outcomes between intentional and accidental fallers. We retrospectively reviewed 49 fallers who fell from heights of ≥6 m, developed pelvic and acetabular fractures, survived after resuscitation, and completed surgical treatment between 2014 and 2017. Fallers were divided into intentional and accidental fallers. Sixteen patients were intentional fallers, whereas the rest of the patients were accidental fallers. Psychiatric counseling was provided to each of the intentional fallers during follow-up. All intentional fallers had preexisting mental disorders, and the most common diagnosis was adjustment disorder. The group of intentional fallers predominantly comprised females that had a higher injury and new injury severity scores and longer hospital stays. However, early loss of fixation (<3 months) and functional outcomes (Merle d’Aubigné and Majeed hip scores at 6- and 12-month follow-ups) did not significantly differ between intentional and accidental fallers. We found that intentional fallers with pelvic and acetabular fractures may have more severe combined injuries compared to accidental fallers. However, the radiological and functional outcomes of the intentional fallers after osteosynthesis were not inferior to those of the accidental fallers with the implementation of well-designed surgical protocols and individualized physical and mental rehabilitation programs.
Keywords	Medicine ; R
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Intentional Fallers with Complex Pelvic and Acetabular Fractures Do Not Have worse Radiological and Functional Outcomes than Accidental Fallers.

Yu, Yi-Hsun / Chou, Ying-Chao / Yeh, Bo-Yan / Hsu, Yung-Heng / Chen, I-Jung / Wei, Lien-Chung

BioMed research international

2022 Volume 2022, Page(s) 8292345

Abstract	Individuals who fall from heights of ≥6 m can suffer from complex pelvic and acetabular fractures. The extent to which an intentional fall correlates with prognosis and outcome after osteosynthesis is unclear. Therefore, we aimed to investigate the clinical outcomes of fallers with pelvic and acetabular fractures after osteosynthesis and compare the radiological and functional outcomes between intentional and accidental fallers. We retrospectively reviewed 49 fallers who fell from heights of ≥6 m, developed pelvic and acetabular fractures, survived after resuscitation, and completed surgical treatment between 2014 and 2017. Fallers were divided into intentional and accidental fallers. Sixteen patients were intentional fallers, whereas the rest of the patients were accidental fallers. Psychiatric counseling was provided to each of the intentional fallers during follow-up. All intentional fallers had preexisting mental disorders, and the most common diagnosis was adjustment disorder. The group of intentional fallers predominantly comprised females that had a higher injury and new injury severity scores and longer hospital stays. However, early loss of fixation (<3 months) and functional outcomes (Merle d'Aubigné and Majeed hip scores at 6- and 12-month follow-ups) did not significantly differ between intentional and accidental fallers. We found that intentional fallers with pelvic and acetabular fractures may have more severe combined injuries compared to accidental fallers. However, the radiological and functional outcomes of the intentional fallers after osteosynthesis were not inferior to those of the accidental fallers with the implementation of well-designed surgical protocols and individualized physical and mental rehabilitation programs.
MeSH term(s)	Accidental Falls ; Acetabulum/diagnostic imaging ; Acetabulum/injuries ; Acetabulum/surgery ; Adult ; Female ; Fracture Fixation, Internal ; Hip Fractures/diagnostic imaging ; Hip Fractures/surgery ; Humans ; Male ; Middle Aged ; Pelvic Bones/diagnostic imaging ; Pelvic Bones/injuries ; Pelvic Bones/surgery ; Retrospective Studies
Language	English
Publishing date	2022-01-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2022/8292345
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Smart near infrared-responsive nanocomposite hydrogels for therapeutics and diagnostics

Shen, Ke-Han / Lu, Cheng-Hsun / Kuo, Chih-Yu / Li, Bo-Yan / Yeh, Yi-Cheun

Journal of materials chemistry B. 2021 Sept. 15, v. 9, no. 35

2021

Abstract	Nanocomposite (NC) hydrogels are emerging biomaterials that possess desirable and defined properties and functions for therapeutics and diagnostics. Particularly, nanoparticles (NPs) are employed as stimulus-transducers in NC hydrogels to facilitate the treatment process by providing controllable structural change and payload release under internal and external simulations. Among the various external stimuli, near-infrared (NIR) light has attracted considerable interest due to its minimal photo-damage, deep tissue penetration, low auto-fluorescence in living systems, facile on/off switch, easy remote and spatiotemporal control. In this study, we discuss four types of transducing nanomaterials used in NIR-responsive NC hydrogels, including metal-based nanoparticles, carbon-based nanomaterials, polydopamine nanoparticles (PDA NPs), and upconversion nanoparticles (UCNPs). This review provides an overview of the current progress in NIR-responsive NC hydrogels, focusing on their preparation, properties, applications, and future prospects.
Keywords	biocompatible materials ; diagnostic techniques ; hydrogels ; nanocomposites ; therapeutics
Language	English
Dates of publication	2021-0915
Size	p. 7100-7116.
Publishing place	The Royal Society of Chemistry
Document type	Article
ZDB-ID	2702241-9
ISSN	2050-7518 ; 2050-750X
ISSN (online)	2050-7518
ISSN	2050-750X
DOI	10.1039/d1tb00980j
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Efficacy of Electronic Acupuncture Shoes for Chronic Low Back Pain: Double-Blinded Randomized Controlled Trial.

Yeh, Bo-Yan / Liu, Geng-Hao / Lee, Tzung-Yan / Wong, Alice May-Kuen / Chang, Hen-Hong / Chen, Yu-Sheng

Journal of medical Internet research

2020 Volume 22, Issue 10, Page(s) e22324

Abstract: Background: Chronic low back pain is a common problem and is associated with high costs, including those related to health care and indirect costs due to absence at work or reduced productivity. Previous studies have demonstrated that acupuncture or ... ...

Abstract	Background: Chronic low back pain is a common problem and is associated with high costs, including those related to health care and indirect costs due to absence at work or reduced productivity. Previous studies have demonstrated that acupuncture or electroacupuncture can relieve low back pain. Electronic acupuncture shoes (EAS) are a novel device designed in this study. This device combines the properties of acupuncture and transcutaneous electrical nerve stimulation for clinical use. Objective: The aim of this study was to evaluate the efficacy of EAS in patients with chronic low back pain. Methods: In this prospective double-blinded randomized controlled study, the data of 83 patients who experienced chronic low back pain were analyzed. Patients came to our clinic for 20 visits and underwent assessment and treatment. Patients were randomly allocated to receive either EAS plus placebo nonsteroidal anti-inflammatory drugs (NSAIDs) (EAS group, n=42) or sham EAS plus NSAIDs (NSAID group, n=41). The visual analog scale (VAS) score and range of motion were assessed at baseline, before and after each EAS treatment, and 2 weeks after the last treatment. The time for achieving pain remission was recorded. Quality of life was assessed at the 2nd, 14th, and 20th visits. Results: After 6 weeks of treatment, the treatment success rate in each visit in the EAS group was higher than that in the NSAID group, as revealed by the intention-to-treat (ITT) and per-protocol (PP) analyses, but significant differences were observed only during the 16th visit in the ITT analysis (EAS group: 31/37, 84% and NSAID group: 21/34, 62%; P=.04). The change in the VAS score from baseline in each visit in the EAS group was greater than that in the NSAID group, as revealed by the ITT and PP analyses, and significant differences were observed in the 5th visit and 9th visit in the ITT analysis (P=.048 and P=.048, respectively). Significant differences were observed in the left rotation in the 2nd visit and 4th visit (P=.049 and P=.03, respectively). No significant differences were observed in the VAS score before and after treatment in each visit and in the quality of life in both groups. Conclusions: EAS might serve as a reliable alternative therapeutic tool for patients with chronic low back pain who are contraindicated for oral NSAIDs. Trial registration: ClinicalTrials.gov NCT02468297 https://clinicaltrials.gov/ct2/show/NCT02468297.
MeSH term(s)	Acupuncture Therapy/methods ; Adult ; Chronic Pain/therapy ; Double-Blind Method ; Female ; Humans ; Low Back Pain/therapy ; Male ; Middle Aged ; Pain Measurement/methods ; Prospective Studies ; Quality of Life/psychology ; Shoes/standards ; Treatment Outcome ; Young Adult
Keywords	covid19
Language	English
Publishing date	2020-10-26
Publishing country	Canada
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2028830-X
ISSN	1438-8871 ; 1439-4456
ISSN (online)	1438-8871
ISSN	1439-4456
DOI	10.2196/22324
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Using a consensus acupoints regimen to explore the relationship between acupuncture sensation and lumbar spinal postoperative analgesia: A retrospective analysis of prospective clinical cooperation.

Chao, Yen-Lin / Rau, Yi-Ai / Shiue, Hong-Sheng / Yan, Jiun-Lin / Tang, Yuan-Yun / Yu, Shao-Wen / Yeh, Bo-Yan / Chen, Yen-Lung / Yang, Tsung-Hsien / Cheng, Shu-Chen / Hsieh, Yi-Wen / Huang, Hsin-Chia / Tsai, Fu-Kuang / Chen, Yu-Sheng / Liu, Geng-Hao

Journal of integrative medicine

2022 Volume 20, Issue 4, Page(s) 329–337

Abstract: Objective: This study evaluated the effectiveness of acupuncture treatment on postoperative pain in patients with degenerative lumbar spine disease, and explored the relationship between the postoperative analgesic effect of acupuncture and the ... ...

Abstract	Objective: This study evaluated the effectiveness of acupuncture treatment on postoperative pain in patients with degenerative lumbar spine disease, and explored the relationship between the postoperative analgesic effect of acupuncture and the sensation of acupuncture experienced by the patients. Methods: This retrospective study analyzed the medical records of 97 patients who had undergone an operation by the same surgeon due to degenerative lumbar disease. These patients were divided into acupuncture group (n = 32), patient-controlled analgesia (PCA) group (n = 27), and oral analgesia group (n = 38) according to the different postoperative analgesic methods. During their hospitalization, patients completed daily evaluations of their pain using a visual analogue scale (VAS), and injection times of supplemental meperidine were recorded. Also, the Chinese version of the Massachusetts General Hospital Acupuncture Sensation Scale (C-MASS) was used in the acupuncture group. Results: Each of the three treatment groups showed significant reductions in postoperative pain, as shown by reduced VAS scores. The acupuncture group, however, had less rebound pain (P < 0.05) than the other two groups. Both the acupuncture and PCA groups experienced acute analgesic effects that were superior to those in the oral analgesia group. In addition, the higher the C-MASS index on the second day after surgery, the lower the VAS score on the fourth day after surgery. There was also a significant difference in the "dull pain" in the acupuncture sensation. Conclusion: The results demonstrated that acupuncture was beneficial for postoperative pain and discomfort after simple surgery for degenerative spinal disease. It is worth noting that there was a disproportionate relevance between the patient's acupuncture sensation and the improvement of pain VAS score.
MeSH term(s)	Acupuncture Points ; Acupuncture Therapy ; Analgesia/methods ; Analgesics/therapeutic use ; Consensus ; Humans ; Pain, Postoperative/drug therapy ; Prospective Studies ; Retrospective Studies ; Sensation
Chemical Substances	Analgesics
Language	English
Publishing date	2022-04-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2705612-0
ISSN	2095-4964
ISSN	2095-4964
DOI	10.1016/j.joim.2022.04.003
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 6322: Show issues

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Article: Associations Between Using Chinese Herbal Medicine and Long-Term Outcome Among Pre-dialysis Diabetic Nephropathy Patients: A Retrospective Population-Based Cohort Study.

Guo, Jenny Chun-Ling / Pan, Heng-Chih / Yeh, Bo-Yan / Lu, Yen Chu / Chen, Jiun-Liang / Yang, Ching-Wei / Chen, Yu-Chun / Lin, Yi-Hsuan / Chen, Hsing-Yu

Frontiers in pharmacology

2021 Volume 12, Page(s) 616522

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-02-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2021.616522
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Research on the tilt-to-length coupling noise suppression method inside the gravitational wave detection telescope.

Fan, Wen Tong / Song, Jie / Hai, Hong Wen / Fang, Si Jun / Zhao, Kai / Zhang, Rui / Li, Bo Hong / Luo, Jian / Sun, Qi Cheng / Fan, Lei / Li, Zi Zheng / Yeh, Hsien-Chi / Yan, Yong

Optics express

2024 Volume 32, Issue 7, Page(s) 12200–12212

Abstract: As an integral component of the laser interferometry measurement system, the tilt-to-length (TTL) coupling noise inside the telescope stands out as a critical noise factor that requires meticulous consideration. In the TianQin project, the non-geometric ... ...

Abstract	As an integral component of the laser interferometry measurement system, the tilt-to-length (TTL) coupling noise inside the telescope stands out as a critical noise factor that requires meticulous consideration. In the TianQin project, the non-geometric TTL-coupled noise inside the telescope should be less than 0.22 pm/Hz
Language	English
Publishing date	2024-04-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.512394
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