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  1. Article ; Online: Wildfire smoke knows no borders: Differential vulnerability to smoke effects on cardio-respiratory health in the San Diego-Tijuana region.

    Schwarz, Lara / Aguilera, Rosana / Aguilar-Dodier, L C / Castillo Quiñones, Javier Emmanuel / García, María Evarista Arellano / Benmarhnia, Tarik

    PLOS global public health

    2023  Volume 3, Issue 6, Page(s) e0001886

    Abstract: ... to different health effects across populations. While the San Diego-Tijuana border can be exposed to the same ... of wildfire smoke on cardio-respiratory hospitalizations in the Municipality of Tijuana and San Diego County ... respiratory diseases occurred in San Diego County while 37 hospital admissions were reported in the Municipality ...

    Abstract Exposure to fine particles in wildfire smoke is deleterious for human health and can increase cases of cardio-respiratory illnesses and related hospitalizations. Neighborhood-level risk factors can increase susceptibility to environmental hazards, such as air pollution from smoke, and the same exposure can lead to different health effects across populations. While the San Diego-Tijuana border can be exposed to the same wildfire smoke event, socio-demographic differences may drive differential effects on population health. We used the October 2007 wildfires, one the most devastating wildfire events in Southern California that brought smoke to the entire region, as a natural experiment to understand the differential effect of wildfire smoke on both sides of the border. We applied synthetic control methods to evaluate the effects of wildfire smoke on cardio-respiratory hospitalizations in the Municipality of Tijuana and San Diego County separately. During the study period (October 11th- October 26th, 2007), 2009 hospital admissions for cardio-respiratory diseases occurred in San Diego County while 37 hospital admissions were reported in the Municipality of Tijuana. The number of cases in Tijuana was much lower than San Diego, and a precise effect of wildfire smoke was detected in San Diego but not in Tijuana. However, social drivers can increase susceptibility to environmental hazards; the poverty rate in Tijuana is more than three times that of San Diego. Socio-demographics are important in modulating the effects of wildfire smoke and can be potentially useful in developing a concerted regional effort to protect populations on both sides of the border from the adverse health effects of wildfire smoke.
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3375
    ISSN (online) 2767-3375
    DOI 10.1371/journal.pgph.0001886
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The potential impact of wildfire smoke on COVID-19 cumulative deaths in the San Diego-Tijuana border region

    Lara Schwarz / Rosana Aguilera / Javier Emmanuel Castillo Quiñones / L C Aguilar-Dodier / María Evarista Arellano García / Tarik Benmarhnia

    Environmental Research: Health, Vol 1, Iss 2, p

    2023  Volume 021004

    Abstract: ... Capitalizing on wildfire smoke that hit the San Diego-Tijuana border region in September 2020, we applied ... as potential controls. The San Diego-Tijuana border region was covered by dense smoke by the 7th of September ... 707 COVID-19 deaths had occurred in San Diego and 1367 in Tijuana. While a slight increase ...

    Abstract 2020 broke records for the most active fire year on the West Coast, resulting in the worst air quality observed in decades. Concurrently, the public health threat of COVID-19 caused over 1 million deaths in the United States (US) and Mexico in 2020 and 2021. Due to the effect of air pollution on respiratory diseases, wildfire-specific particulate matter is a hypothesized driver of COVID-19 severity and death. Capitalizing on wildfire smoke that hit the San Diego-Tijuana border region in September 2020, we applied synthetic control methods to explore its potential differential role in affecting COVID-19 mortality on both sides of the border. Daily data on COVID-19 cumulative deaths for US counties were obtained from the CDC COVID tracker and data for Mexican municipalities was obtained from the Mexican Secretary of Health. Counties and municipalities with wildfire smoke exposure were identified using the National Oceanic and Atmospheric Administration hazard mapping smoke product (HMS); a day where 90% of the area was covered by smoke was considered exposed for the main analyses. Unexposed counties/municipalities were considered as potential controls. The San Diego-Tijuana border region was covered by dense smoke by the 7th of September; 707 COVID-19 deaths had occurred in San Diego and 1367 in Tijuana. While a slight increase in cumulative mortality was observed in San Diego, no change was found in Tijuana; neither estimate indicated a strong precise effect of wildfire smoke on COVID-19 mortality. We hope this study will serve as an illustration of how border contexts can be used to investigate differential vulnerability to wildfire smoke for infectious diseases. Examining the interactive effect of COVID-19 and smoke can help in recognizing the implications of these dual health risks which will be increasingly important as wildfires become more frequent and severe in the context of climate change.
    Keywords border health ; wildfire smoke ; COVID-19 ; synthetic control methods ; Environmental sciences ; GE1-350 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher IOP Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Racial/ethnic disparities in the association between fine particles and respiratory hospital admissions in San Diego county, CA.

    Mehta, Shivani / Vashishtha, Devesh / Schwarz, Lara / Corcos, Isabel / Gershunov, Alexander / Guirguis, Kristen / Basu, Rupa / Benmarhnia, Tarik

    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering

    2021  Volume 56, Issue 4, Page(s) 473–480

    Abstract: ... with regards to respiratory hospital admissions in San Diego County, California where most days fall below ... from monitor networks. The association between daily PM 2.5 levels and respiratory hospital admissions in San Diego ...

    Abstract Ambient air pollution exposure is associated with exacerbating respiratory illnesses. Race/ethnicity (R/E) have been shown to influence an individual's vulnerability to environmental health risks such as fine particles (PM 2.5). This study aims to assess the R/E disparities in vulnerability to air pollution with regards to respiratory hospital admissions in San Diego County, California where most days fall below National Ambient Air Quality Standards (NAAQS) for daily PM 2.5 concentrations. Daily PM 2.5 levels were estimated at the zip code level using a spatial interpolation using inverse-distance weighting from monitor networks. The association between daily PM 2.5 levels and respiratory hospital admissions in San Diego County over a 15-year period from 1999 to 2013 was assessed with a time-series analysis using a multi-level Poisson regression model. Cochran Q tests were used to assess the effect modification of race/ethnicity on this association. Daily fine particle levels varied greatly from 1 μg/m
    Language English
    Publishing date 2021-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 196584-0
    ISSN 1532-4117 ; 0360-1226 ; 1077-1204 ; 1093-4529
    ISSN (online) 1532-4117
    ISSN 0360-1226 ; 1077-1204 ; 1093-4529
    DOI 10.1080/10934529.2021.1887686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Heat Waves and Emergency Department Visits Among the Homeless, San Diego, 2012-2019.

    Schwarz, Lara / Castillo, Edward M / Chan, Theodore C / Brennan, Jesse J / Sbiroli, Emily S / Carrasco-Escobar, Gabriel / Nguyen, Andrew / Clemesha, Rachel E S / Gershunov, Alexander / Benmarhnia, Tarik

    American journal of public health

    2021  Volume 112, Issue 1, Page(s) 98–106

    Abstract: Objectives. ...

    Abstract Objectives.
    MeSH term(s) Adult ; Aged ; California/epidemiology ; Cross-Over Studies ; Datasets as Topic ; Emergency Service, Hospital/statistics & numerical data ; Extreme Heat ; Ill-Housed Persons/statistics & numerical data ; Humans ; Middle Aged ; Social Determinants of Health ; Social Vulnerability ; Sociodemographic Factors
    Language English
    Publishing date 2021-12-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 121100-6
    ISSN 1541-0048 ; 0090-0036 ; 0002-9572
    ISSN (online) 1541-0048
    ISSN 0090-0036 ; 0002-9572
    DOI 10.2105/AJPH.2021.306557
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Search for Contributors to Low Rates of Recognition of Paternal Alcohol Use Disorders in Offspring From the San Diego Prospective Study.

    Schuckit, Marc A / Clarke, Dennis F / Smith, Tom L / Mendoza, Lee Anne / Schoen, Lara

    Alcoholism, clinical and experimental research

    2020  Volume 44, Issue 8, Page(s) 1551–1560

    Abstract: ... informants or their AUD fathers.: Methods: Data from the San Diego Prospective Study (SDPS ...

    Abstract Background: The most efficient approach for establishing family histories (FHs) asks informants about disorders in their relatives (a Family History Method [FHM]). However, FHMs underestimate family diagnoses. We evaluated if accuracies of young adult offspring report of their father's alcohol use disorders (AUDs) related to the age, sex, education, and/or substance-related patterns/problems of either the young adult informants or their AUD fathers.
    Methods: Data from the San Diego Prospective Study (SDPS), a multigenerational 35-year investigation, compared father/offspring pairs where the proband father's alcohol problems were correctly (Group 1) or incorrectly (Group 2) noted by offspring. In the key analysis, Group 1 versus 2 results were entered into bootstrapped backward logistic regression analyses predicting Group 1 membership.
    Results: Five proband and one offspring characteristic were associated with correct identification of their father's alcohol problems. None of these related to age, education, or sex. Characteristics associated with correct FHM diagnoses included the father's FH of AUDs, self-report of drinking despite social/interpersonal or physical/psychological alcohol-related problems, spending much time related to alcohol, and his having a religious preference. The single offspring item predicting correct identification of the father's problems was the number of DSM alcohol problems of the offspring.
    Conclusions: In the SDPS, FHM sensitivity was most closely related to the father's drinking characteristics, not the offspring characteristics. While unique aspects of SDPS families potentially limit generalizability of results, the data demonstrate how the FHM can offer important initial steps in the search for genetically related AUD risks in a subset of families.
    MeSH term(s) Adult ; Age Factors ; Alcoholism ; Child of Impaired Parents ; Educational Status ; Fathers ; Female ; Humans ; Logistic Models ; Longitudinal Studies ; Male ; Medical History Taking ; Middle Aged ; Prospective Studies ; Self Report ; Sex Factors ; Young Adult
    Language English
    Publishing date 2020-07-16
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 428999-7
    ISSN 1530-0277 ; 0145-6008
    ISSN (online) 1530-0277
    ISSN 0145-6008
    DOI 10.1111/acer.14401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Predictors of Increases in Alcohol Problems and Alcohol Use Disorders in Offspring in the San Diego Prospective Study.

    Schuckit, Marc A / Smith, Tom L / Clarke, Dennis / Mendoza, Lee Anne / Kawamura, Mari / Schoen, Lara

    Alcoholism, clinical and experimental research

    2019  Volume 43, Issue 10, Page(s) 2232–2241

    Abstract: Background: The 35-year-long San Diego Prospective Study documented 2-fold increases in alcohol ...

    Abstract Background: The 35-year-long San Diego Prospective Study documented 2-fold increases in alcohol problems and alcohol use disorders (AUDs) in young-adult drinking offspring compared to rates in their fathers, the original probands. The current analyses use the same interviews and questionnaires at about the same age in members of the 2 generations to explore multiple potential contributors to the generational differences in adverse alcohol outcomes.
    Methods: Using data from recent offspring interviews, multiple cross-generation differences in characteristics potentially related to alcohol problems were evaluated in 3 steps: first through direct comparisons across probands and offspring at about age 30; second by backward linear regression analyses of predictors of alcohol problems within each generation; and finally third through R-based bootstrapped linear regressions of differences in alcohol problems in randomly matched probands and offspring.
    Results: The analyses across the analytical approaches revealed 3 consistent predictors of higher alcohol problems in the second generation. These included the following: (i) a more robust relationship to alcohol problems for offspring with a low level of response to alcohol; (ii) higher offspring values for alcohol expectancies; and (iii) higher offspring impulsivity.
    Conclusions: The availability of data across generations offered a unique perspective for studying characteristics that may have contributed to a general finding in the literature of substantial increases in alcohol problems and AUDs in recent generations. If replicated, these results could suggest approaches to be used by parents, healthcare workers, insurance companies, and industry in their efforts to mitigate the increasing rates of alcohol problems in younger generations.
    MeSH term(s) Adolescent ; Adult ; Alcohol Drinking ; Alcoholism/epidemiology ; Alcoholism/genetics ; California/epidemiology ; Central Nervous System Depressants/pharmacology ; Ethanol/pharmacology ; Family Characteristics ; Female ; Humans ; Impulsive Behavior ; Longitudinal Studies ; Male ; Motivation ; Prospective Studies ; Young Adult
    Chemical Substances Central Nervous System Depressants ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2019-08-27
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 428999-7
    ISSN 1530-0277 ; 0145-6008
    ISSN (online) 1530-0277
    ISSN 0145-6008
    DOI 10.1111/acer.14164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Racial/ethnic disparities in the association between fine particles and respiratory hospital admissions in San Diego county, CA

    Mehta, Shivani / Vashishtha, Devesh / Schwarz, Lara / Corcos, Isabel / Gershunov, Alexander / Guirguis, Kristen / Basu, Rupa / Benmarhnia, Tarik

    Journal of environmental science and health. 2021 Mar. 21, v. 56, no. 4

    2021  

    Abstract: ... with regards to respiratory hospital admissions in San Diego County, California where most days fall below ... from monitor networks. The association between daily PM 2.5 levels and respiratory hospital admissions in San Diego ... that address the unequal burden of air pollution among vulnerable communities in San Diego County that exist ...

    Abstract Ambient air pollution exposure is associated with exacerbating respiratory illnesses. Race/ethnicity (R/E) have been shown to influence an individual’s vulnerability to environmental health risks such as fine particles (PM 2.5). This study aims to assess the R/E disparities in vulnerability to air pollution with regards to respiratory hospital admissions in San Diego County, California where most days fall below National Ambient Air Quality Standards (NAAQS) for daily PM 2.5 concentrations. Daily PM 2.5 levels were estimated at the zip code level using a spatial interpolation using inverse-distance weighting from monitor networks. The association between daily PM 2.5 levels and respiratory hospital admissions in San Diego County over a 15-year period from 1999 to 2013 was assessed with a time-series analysis using a multi-level Poisson regression model. Cochran Q tests were used to assess the effect modification of race/ethnicity on this association. Daily fine particle levels varied greatly from 1 μg/m³ to 75.86 μg/m³ (SD = 6.08 μg/m³) with the majority of days falling below 24-hour NAAQS for PM 2.5 of 35 μg/m³. For every 10 μg/m³ increase in PM 2.5 levels, Black and White individuals had higher rates (8.6% and 6.2%, respectively) of hospitalization for respiratory admissions than observed in the county as a whole (4.1%). Increases in PM 2.5 levels drive an overall increase in respiratory hospital admissions with a disparate burden of health effects by R/E group. These findings suggest an opportunity to design interventions that address the unequal burden of air pollution among vulnerable communities in San Diego County that exist even below NAAQS for daily PM 2.5 concentrations.
    Keywords air pollution ; air quality ; environmental health ; hospitals ; nationalities and ethnic groups ; regression analysis ; time series analysis ; California
    Language English
    Dates of publication 2021-0321
    Size p. 473-480.
    Publishing place Taylor & Francis
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 196584-0
    ISSN 1532-4117 ; 0360-1226 ; 1077-1204 ; 1093-4529
    ISSN (online) 1532-4117
    ISSN 0360-1226 ; 1077-1204 ; 1093-4529
    DOI 10.1080/10934529.2021.1887686
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Validation of the Temperament Evaluation of Memphis, Pisa, Paris and San Diego (TEMPS-A): Portuguese-Lisbon version.

    Figueira, M Luisa / Caeiro, Lara / Ferro, Ana / Severino, Lara / Duarte, Pedro M / Abreu, Manuela / Akiskal, Hagop S / Akiskal, Kareen K

    Journal of affective disorders

    2008  Volume 111, Issue 2-3, Page(s) 193–203

    Abstract: Background: The TEMPS-A has been validated in 8 languages, the original being American English, and includes among others such Latin languages as Italian, French, and Spanish-Buenos Aires. This is the first Portuguese-Lisbon validation.: Methods: The ...

    Abstract Background: The TEMPS-A has been validated in 8 languages, the original being American English, and includes among others such Latin languages as Italian, French, and Spanish-Buenos Aires. This is the first Portuguese-Lisbon validation.
    Methods: The sample included 1173 students from six different universities and representing most disciplines (such as medicine, law, humanities, engineering, etc.), both sexes (67% female), and ages between 17 and 58 (x+/-SD=21+/-4). Standard psychometric tests were used for internal consistency, validity, and factor analysis.
    Results: The study upheld the 5 Factor proposed structure of TEMPS-A. Cronbach alpha varied from 0.67 for the depressive and 0.83 for the anxious, with the others in-between. We could retain all 110 items of the Interview Schedule. The highest mean scores were found for the hyperthymic, and the lowest for the irritable. As expected, depressive and anxious subscales had strong correlations, followed by the cyclothymic and anxious, and cyclothymic and irritable; in exploratory factor analysis, these subscales constituted Factor I, contrasted to the depressive and the hyperthymic as a biphasic continuum (Factor II). Females scored higher on the depressive, cyclothymic and anxious, and the males on hyperthymic and irritable. Overall, however, no temperament was "dominant" in this population, all temperaments z-scores being 3.3-4%!
    Limitations: Study limited to university students of young age.
    Conclusions: TEMPS-A Lisbon is a reliable and valid instrument. The only relatively weak factor is the depressive, which is similar to other language versions. Gender differences and correlations of temperaments are generally similar to other countries. What appears relatively special to the Portuguese is the relatively "balanced" mix of temperaments in this university student population.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Anxiety Disorders/diagnosis ; Anxiety Disorders/psychology ; Cross-Cultural Comparison ; Cyclothymic Disorder/diagnosis ; Cyclothymic Disorder/psychology ; Depressive Disorder/diagnosis ; Depressive Disorder/psychology ; European Continental Ancestry Group ; Factor Analysis, Statistical ; Female ; Humans ; Irritable Mood ; Male ; Middle Aged ; Personality Inventory/statistics & numerical data ; Portugal ; Psychometrics ; Reproducibility of Results ; Sex Factors ; Students/psychology ; Students/statistics & numerical data ; Surveys and Questionnaires ; Temperament ; Translations ; Universities
    Language English
    Publishing date 2008-12
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article ; Multicenter Study
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2008.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Reseña de "Votos ponderados. Sistemas electorales y sobrerrepresentación distrital" de Diego Reynoso

    Hiram A. Ángel Lara

    Región y Sociedad, Vol 17, Iss 34, Pp 175-

    2005  Volume 179

    Keywords Social Sciences ; H ; Social sciences (General) ; H1-99
    Language Spanish
    Publishing date 2005-01-01T00:00:00Z
    Publisher El Colegio de Sonora
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Reseña de "Íconos, figuraciones, sueños. Hermenéutica de las imágenes" de Diego Lizarazo

    Mar\u00EDa Dolores Mor\u00EDn Lara

    Andamios. Revista de Investigación Social, Vol 2, Iss 3, Pp 205-

    2005  Volume 208

    Keywords Social sciences (General) ; H1-99 ; Social Sciences ; H
    Language Spanish
    Publishing date 2005-01-01T00:00:00Z
    Publisher Universidad Autónoma de la Ciudad de México
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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