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Article: Internet Gaming Disorder and Mental Health Literacy: A Latent Profile Analysis of Korean Adolescents.

Yoon, Jiyoung / Chun, JongSerl / Bhang, Soo-Young

2024 Volume 21, Issue 3, Page(s) 300–310

Abstract: Objective: This study identified latent subtypes of mental health literacy (MHL) for Internet gaming disorder (IGD) and explored their characteristics and differences in various factors in adolescents.: Methods: This study analyzed secondary data ... ...

Abstract	Objective: This study identified latent subtypes of mental health literacy (MHL) for Internet gaming disorder (IGD) and explored their characteristics and differences in various factors in adolescents. Methods: This study analyzed secondary data from the 2019 Youth Smart Digital Media Survey and included data from 1,936 middle and high school students (14-18 years old). Thirteen items of the MHL questionnaire were used for latent profile analysis. We compared the characteristics and predictors of the identified types using various statistical analyses, including one-way ANOVA, chi-square test, and multinomial logistic regression. Results: We identified three subtypes of MHL for IGD in adolescents: "low perception-prefer informal resources," "moderate perception-preferred resources unclear," and "high perception-prefer professional resources." Subtypes showed significant differences in sex, age, family affluence, e-learning time during weekdays, mental health risks, level of problematic smartphone use, and IGD. All variables except IGD predicted one or more latent types. Conclusion: Practical interventions are required to improve IGD MHL, including customized prevention based on the differences between the three types.
Language	English
Publishing date	2024-03-25
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2414364-9
ISSN	1976-3026 ; 1738-3684
ISSN (online)	1976-3026
ISSN	1738-3684
DOI	10.30773/pi.2023.0303
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Zs.A 6598: Show issues

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Article ; Online: Optimized Method for Mycobacteria DNA Extraction from Sputum for Isothermal Amplification.

Mun, Byoung-Sun / Yoon, Jung / Yoon, Soo-Young

Annals of clinical and laboratory science

2023 Volume 53, Issue 3, Page(s) 476–481

Abstract: Objective: Sputum sample processing for mycobacterial DNA extraction are demanding process to be integrated into isothermal amplification techniques because they often require procedures with number of centrifugation steps and manual interventions. Here, ...

Abstract	Objective: Sputum sample processing for mycobacterial DNA extraction are demanding process to be integrated into isothermal amplification techniques because they often require procedures with number of centrifugation steps and manual interventions. Here, we established simple use of robust mycobacterial DNA extraction protocol from sputum samples suitable for isothermal amplification technique. Methods: The DNA extraction efficiency of each protocol was evaluated using Results: Of three mycobacteria lysis methods, the difference of cycle threshold (Ct) values between for Conclusion: DNA extraction by thermal lysis at 65°C with GuSCN followed by spin column DNA purification is simple, relatively fast (less than 50 min) and robust protocol applicable for downstream isothermal amplification.
MeSH term(s)	Humans ; Mycobacterium bovis/genetics ; Sputum/microbiology ; Genetic Techniques/standards ; Nontuberculous Mycobacteria/genetics ; DNA, Bacterial/isolation & purification
Chemical Substances	guanidine thiocyanate (593-84-0) ; DNA, Bacterial
Language	English
Publishing date	2023-07-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	193092-8
ISSN	1550-8080 ; 0091-7370 ; 0095-8905
ISSN (online)	1550-8080
ISSN	0091-7370 ; 0095-8905
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Zs.A 942: Show issues

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Article ; Online: Febrile infants: written guidelines to reduce non-essential hospitalizations.

Oh, Ji Yoon / Lee, Soo-Young

World journal of pediatrics : WJP

2021 Volume 17, Issue 5, Page(s) 555–556

MeSH term(s)	Fever/diagnosis ; Fever/epidemiology ; Fever/therapy ; Hospitalization ; Humans ; Infant
Language	English
Publishing date	2021-08-26
Publishing country	Switzerland
Document type	Letter
ZDB-ID	2236681-7
ISSN	1867-0687 ; 1708-8569
ISSN (online)	1867-0687
ISSN	1708-8569
DOI	10.1007/s12519-021-00456-7
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Zs.A 6309: Show issues

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Article ; Online: Comparative study of i-SENS glucometers in neonates using capillary blood samples.

Kim, Ha Nui / Yoon, Soo-Young

Clinical chemistry and laboratory medicine

2021 Volume 59, Issue 6, Page(s) 1133–1141

Abstract: Objectives: The accuracy of point-of-care blood glucometers in the detection and evaluation of neonatal hypoglycemia is a concern. This study compared the performance of three i-SENS glucometers with that of the YSI 2300 STAT Plus Analyzer, which was ... ...

Abstract	Objectives: The accuracy of point-of-care blood glucometers in the detection and evaluation of neonatal hypoglycemia is a concern. This study compared the performance of three i-SENS glucometers with that of the YSI 2300 STAT Plus Analyzer, which was used as a reference. Methods: The leftover neonatal capillary blood samples of 319 patients were used in this study. The evaluation process and accuracy performance criteria were based on the International Organization for Standardization 15197:2013 guidelines. The evaluation involved three i-SENS glucometers (BAROzen H Expert plus, CareSens PRO, and CareSens H Beat) and the ACCU-CHEK Results: The accuracy evaluation yielded acceptable results as follows: a) 100 and 100% for BAROzen H Expert plus; 99.8 and 100% for CareSens PRO; 98.7%, and 97.2% for CareSens H Beat glucometers were within the range of ±0.8 mmol/L (15 mg/dL) and ±15% of the average reference values at glucose concentrations <5.55 mmol/L (100 mg/dL) and ≥5.55 mmol/L (100 mg/dL), respectively, and b) all estimated glucose values (100%) were within the zones A and B of Consensus Error Grid for all three i-SENS glucometers. There was good correlation between the glucose values estimated by the glucometers and the reference values (R>0.990). Conclusions: This study demonstrated that i-SENS glucometers exhibit acceptable performance and can be used as effective point-of-care devices in neonates.
MeSH term(s)	Blood Glucose ; Blood Glucose Self-Monitoring ; Glucose ; Humans ; Hypoglycemia ; Infant, Newborn ; Point-of-Care Systems ; Reproducibility of Results
Chemical Substances	Blood Glucose ; Glucose (IY9XDZ35W2)
Language	English
Publishing date	2021-01-22
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1418007-8
ISSN	1437-4331 ; 1434-6621 ; 1437-8523
ISSN (online)	1437-4331
ISSN	1434-6621 ; 1437-8523
DOI	10.1515/cclm-2020-1367
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Article ; Online: Simultaneous point-of-care testing of blood lipid profile and glucose: Performance evaluation of the GCare Lipid Analyzer.

Kim, Ha Nui / Yoon, Soo-Young

Journal of clinical laboratory analysis

2021 Volume 35, Issue 12, Page(s) e24055

Abstract: Background: Point-of-care (POC) testing provides quick results and includes tests for blood glucose and lipid profiles. We evaluated the newly developed POC device, the GCare Lipid Analyzer, which is used to measure glucose, total cholesterol (TC), ... ...

Abstract	Background: Point-of-care (POC) testing provides quick results and includes tests for blood glucose and lipid profiles. We evaluated the newly developed POC device, the GCare Lipid Analyzer, which is used to measure glucose, total cholesterol (TC), triglyceride (TG), and high-density lipoprotein cholesterol (HDL-C) levels. Methods: Venous and capillary blood samples were collected from patients who visited Korea University Guro Hospital. The results obtained using the GCare Lipid Analyzer were compared with those obtained using the TBA 2000FR chemistry analyzer and YSI 2300 STAT Plus analyzer. The glucose system evaluation process was based on the International Organization for Standardization 15197:2013 guidelines. Results: The correlation coefficients (R) for TC, TG, and HDL-C were 0.965, 0.969, and 0.943 in capillary blood and 0.969, 0.990, and 0.956 in venous blood, respectively. The total errors for TC, TG, and HDL-C of the lipid profile using venous blood were all acceptable at 6.6%, 9.3%, and 11.6%, respectively. For glucose concentrations <100 mg/dl, 96.1% of the measured glucose levels were within ±15 mg/dl in venous samples and 100% were within ±15 mg/dl in capillary samples. For glucose concentrations ≥100 mg/dl, 100% and 99.5% of the measured glucose levels were within 15% for venous and capillary blood, respectively. Conclusion: The performance of the GCare Lipid Analyzer is acceptable for both blood glucose and lipid profile testing, indicating that it is reliable for use in patients with diabetic dyslipidemia.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Blood Chemical Analysis/instrumentation ; Blood Chemical Analysis/methods ; Blood Chemical Analysis/standards ; Blood Glucose/analysis ; Cholesterol/blood ; Cholesterol, HDL/blood ; Humans ; Lipids/analysis ; Middle Aged ; Point-of-Care Testing ; Triglycerides/blood ; Young Adult
Chemical Substances	Blood Glucose ; Cholesterol, HDL ; Lipids ; Triglycerides ; Cholesterol (97C5T2UQ7J)
Language	English
Publishing date	2021-10-25
Publishing country	United States
Document type	Evaluation Study ; Journal Article
ZDB-ID	645095-7
ISSN	1098-2825 ; 0887-8013
ISSN (online)	1098-2825
ISSN	0887-8013
DOI	10.1002/jcla.24055
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Zs.A 2471: Show issues

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Article ; Online: Performance of ivisen IA-1400, a new point-of-care device with an internal centrifuge system, for the measurement of cardiac troponin I levels.

Kim, Ha Nui / Yoon, Soo-Young

Journal of clinical laboratory analysis

2021 Volume 35, Issue 5, Page(s) e23747

Abstract: Background: We present the analytical performance of the ivisen IA-1400, a new point-of-care device that features a characteristic built-in centrifuge system, to measure blood cardiac troponin I (cTnI) levels.: Methods: Whole blood and plasma samples ...

Abstract	Background: We present the analytical performance of the ivisen IA-1400, a new point-of-care device that features a characteristic built-in centrifuge system, to measure blood cardiac troponin I (cTnI) levels. Methods: Whole blood and plasma samples obtained from patients who visited Korea University Guro Hospital were used to analyze measurement range, cross-reactivity, interference, and sensitivity and specificity. We performed a correlation analysis of the ivisen IA-1400 versus the Access AccuTnI+3 immunoassay using the UniCel™ DxI 800 platform and the PATHFAST™ hs-cTnI assay. Results: Within-run precisions were classified as low, 9.8%; middle, 10.2%; and high, 8.5%. The limit of blank was 3.1 ng/L for plasma samples and 4.3 ng/L for whole blood samples. The limit of detection was 8.4 ng/L for plasma samples and 10.0 ng/L for whole blood samples, respectively. The limit of quantitation at a coefficient of variation of 20% and 10% was 19.5 ng/L and 45.5 ng/L for plasma samples, respectively. The comparative evaluation between the two other assays and ivisen IA-1400 showed excellent correlation, with Spearman's correlation coefficients (R) of 0.992 and 0.985. The sensitivity and specificity of ivisen IA-1400 using the optimum cut-off value of 235 ug/L were 94.6% and 98.2%, respectively. Conclusion: The ivisen IA-1400 showed acceptable and promising performance in cTnI measurements using whole blood and plasma samples, with limited information in the clinical performance. The flexibility for sample selection using the internal centrifugation system is the main advantage of this point-of-care device.
MeSH term(s)	Centrifugation/instrumentation ; Confidence Intervals ; Cross Reactions ; Humans ; Limit of Detection ; Myocardium/metabolism ; Point-of-Care Systems ; Sensitivity and Specificity ; Troponin I/blood
Chemical Substances	Troponin I
Language	English
Publishing date	2021-03-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	645095-7
ISSN	1098-2825 ; 0887-8013
ISSN (online)	1098-2825
ISSN	0887-8013
DOI	10.1002/jcla.23747
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Zs.A 2471: Show issues

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Article ; Online: Comparison of a new enzymatic assay for serum homocysteine on Toshiba TBA-c16000 against an immunoassay on Abbott Architect.

Kim, Ha Nui / Yoon, Soo-Young

Scandinavian journal of clinical and laboratory investigation

2020 Volume 81, Issue 1, Page(s) 46–51

Abstract: Homocysteine, a risk factor for cardiovascular disease, is commonly analyzed using enzymatic measurements and immunoassays. We compared the results of a new enzymatic assay with those of an immunoassay, using new reagents for homocysteine. The 87 serum ... ...

Abstract	Homocysteine, a risk factor for cardiovascular disease, is commonly analyzed using enzymatic measurements and immunoassays. We compared the results of a new enzymatic assay with those of an immunoassay, using new reagents for homocysteine. The 87 serum samples were analyzed using the Abbott Architect i2000sr (immunoassay) and Toshiba TBA-c16000 (enzymatic assay), and the results obtained from the two assays were compared for precision, correlation, linearity, sample carryover, and reference range verification according to the Clinical and Laboratory Standards Institute guidelines. Repeatability and total imprecision were within the desirable range (Westgard QC, 4.15%). Correlation analysis revealed a strong correlation with a slope ranging from 0.9887 to 1.052, a correlation coefficient (
MeSH term(s)	Enzyme Assays/instrumentation ; Homocysteine/blood ; Humans ; Immunoassay/instrumentation ; Reference Standards ; Regression Analysis ; Time Factors
Chemical Substances	Homocysteine (0LVT1QZ0BA)
Language	English
Publishing date	2020-12-25
Publishing country	England
Document type	Comparative Study ; Journal Article
ZDB-ID	3150-1
ISSN	1502-7686 ; 0036-5513
ISSN (online)	1502-7686
ISSN	0036-5513
DOI	10.1080/00365513.2020.1852597
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Article: Fasting blood glucose and the risk of all-cause mortality in patients with diabetes mellitus undergoing hemodialysis.

Yoon, Soo-Young / Kim, Jin Sug / Ko, Gang Jee / Choi, Yun Jin / Moon, Ju Young / Jeong, Kyunghwan / Hwang, Hyeon Seok

Kidney research and clinical practice

2024

Abstract: Background: Glycemic control is particularly important in hemodialysis (HD) patients with diabetes mellitus (DM). Although fasting blood glucose (FBG) level is an important indicator of glycemic control, a clear target for reducing mortality in HD ... ...

Abstract	Background: Glycemic control is particularly important in hemodialysis (HD) patients with diabetes mellitus (DM). Although fasting blood glucose (FBG) level is an important indicator of glycemic control, a clear target for reducing mortality in HD patients with DM is lacking. Methods: A total of 26,162 maintenance HD patients with DM were recruited from the National Health Insurance Database of Korea between 2002 and 2018. We analyzed the association of FBG levels at the baseline health examination with the risk of all-cause and cause-specific mortality. Results: Patients with FBG 80100 mg/dL showed a higher survival rate compared with that of other FBG categories (p < 0.001). The risk of all-cause mortality increased with the increase in FBG levels, and adjusted hazard ratios (HRs) were 1.10 (95% confidence interval [CI], 1.04-1.17), 1.21 (95% CI, 1.13-1.29), 1.36 (95% CI, 1.26-1.46), and 1.61 (95% CI, 1.51-1.72) for patients with FBG 100-125, 125-150, 150-180, and ≥180 mg/dL, respectively. The HR for mortality was also significantly increased in patients with FBG < 80 mg/dL (adjusted HR, 1.14; 95% CI, 1.05-1.23). The analysis of cause-specific mortality also revealed a J-shaped curve between FBG levels and the risk of cardiovascular deaths. However, the risk of infection or malignancy-related deaths was not linearly increased as FBG levels increased. Conclusion: A J-shaped association was observed between FBG levels and the risk of all-cause mortality, with the lowest risk at FBG 80100 mg/dL in HD patients with DM.
Language	English
Publishing date	2024-01-26
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2656420-8
ISSN	2211-9132
ISSN	2211-9132
DOI	10.23876/j.krcp.23.098
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Article ; Online: Association of the Intensive Blood Pressure Target and Cardiovascular Outcomes in the Population With Chronic Kidney Disease: A Retrospective Study in Korea.

Yoon, Soo-Young / Kong, Ji Yoon / Jeong, Su Jin / Kim, Jin Sug / Hwang, Hyeon Seok / Jeong, Kyunghwan

Journal of the American Heart Association

2024 Volume 13, Issue 6, Page(s) e032186

Abstract: Background: Recently, the target systolic blood pressure (BP) <120 mm Hg was suggested in the population with chronic kidney disease. We aimed to determine the applicability of intensified BP and to assess the incidence of cardiovascular disease (CVD) ... ...

Abstract	Background: Recently, the target systolic blood pressure (BP) <120 mm Hg was suggested in the population with chronic kidney disease. We aimed to determine the applicability of intensified BP and to assess the incidence of cardiovascular disease (CVD) in the population with chronic kidney disease. Methods and results: Participants who were >20 years old and had estimated glomerular filtration rate 15 to 60 mL/min per 1.73 m Conclusions: The new intensive BP target proposed by 2021 Kidney Disease: Improving Global Outcomes should be applied to patients with chronic kidney disease in a personalized and advisory manner.
MeSH term(s)	Adult ; Humans ; Young Adult ; Blood Pressure/physiology ; Retrospective Studies ; Risk Factors ; Hypertension/drug therapy ; Hypertension/epidemiology ; Hypertension/complications ; Cardiovascular Diseases ; Antihypertensive Agents/therapeutic use ; Antihypertensive Agents/pharmacology ; Renal Insufficiency, Chronic/complications ; Kidney Failure, Chronic/complications ; Republic of Korea/epidemiology
Chemical Substances	Antihypertensive Agents
Language	English
Publishing date	2024-03-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2653953-6
ISSN	2047-9980 ; 2047-9980
ISSN (online)	2047-9980
ISSN	2047-9980
DOI	10.1161/JAHA.123.032186
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Article ; Online: Efficacy, tolerability, and safety of oral sulfate tablet versus 2 L-polyethylene glycol/ascorbate for bowel preparation in older patients: prospective, multicenter, investigator single-blinded, randomized study.

Kang, Ho Suk / Na, Soo-Young / Yoon, Jin Young / Jung, Yunho / Seo, Geom Seog / Cha, Jae Myung

Journal of gastroenterology

2024 Volume 59, Issue 5, Page(s) 402–410

Abstract: Background: We compared the efficacy, tolerability, and safety of oral sulfate tablets (OST, which contains simethicone) and 2 L-polyethylene glycol/ascorbate (2 L-PEG/Asc) with a split-dosing regimen in older individuals aged ≥ 70 years who underwent ... ...

Abstract	Background: We compared the efficacy, tolerability, and safety of oral sulfate tablets (OST, which contains simethicone) and 2 L-polyethylene glycol/ascorbate (2 L-PEG/Asc) with a split-dosing regimen in older individuals aged ≥ 70 years who underwent scheduled colonoscopy. Methods: This prospective, randomized, investigator-blinded, multicenter study was conducted between June 2022 and October 2023. Participants aged ≥ 70 years were randomized at a ratio of 1:1 to the OST or 2 L-PEG/Asc groups. Results: In total, 254 patients were evaluated using a modified full analysis set. Successful overall bowel preparation was excellent and similar between the OST and 2 L-PEG/Asc groups for the Boston Bowel Preparation Scale (BBPS) (96.5% vs. 96.6%) and Harefield Cleansing Scale (HCS) (96.5% vs. 97.4%). The overall high-quality preparation rate was higher in the OST group than in the 2 L-PEG/Asc group (BBPS: 55.7% vs. 28.4%, P < 0.001; HCS: 66.1% vs. 38.8%, P < 0.001). The overall adenoma detection rate (54.8% vs. 35.3, P = 0.003) was superior in the OST group compared to the 2 L-PEG/Asc group. Tolerability scores, including overall satisfaction, were generally higher in the OST group than in the 2 L-PEG/Asc group. The incidence of major solicited adverse events was comparable between the two groups (55.7% vs. 68.1, P = 0.051), and there were no clinically significant changes in the serum laboratory profiles on the day of or 7 days after colonoscopy. Conclusions: OST is an effective and safe low-volume agent for colonoscopy, with better tolerance than 2 L-PEG/Asc, in older individuals aged ≥ 70 years.
MeSH term(s)	Humans ; Aged ; Polyethylene Glycols/adverse effects ; Cathartics/adverse effects ; Sulfates ; Prospective Studies ; Laxatives ; Colonoscopy ; Ascorbic Acid/adverse effects
Chemical Substances	Polyethylene Glycols (3WJQ0SDW1A) ; Cathartics ; Sulfates ; Laxatives ; Ascorbic Acid (PQ6CK8PD0R)
Language	English
Publishing date	2024-03-16
Publishing country	Japan
Document type	Randomized Controlled Trial ; Multicenter Study ; Journal Article
ZDB-ID	1186495-3
ISSN	1435-5922 ; 0944-1174
ISSN (online)	1435-5922
ISSN	0944-1174
DOI	10.1007/s00535-024-02089-9
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