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  1. Article ; Online: Acquired Hemophilia A Presenting as Intramuscular Hematoma.

    Al-Shbool, Ghassan / Vakiti, Anusha

    Journal of investigative medicine high impact case reports

    2018  Volume 6, Page(s) 2324709618817572

    Abstract: Acquired hemophilia A poses a clinical and diagnostic challenge. Although rare, it is still the most common acquired factor deficiency. We present a case of acquired hemophilia A diagnosed in a 71-year-old female who presented with a right thigh hematoma ...

    Abstract Acquired hemophilia A poses a clinical and diagnostic challenge. Although rare, it is still the most common acquired factor deficiency. We present a case of acquired hemophilia A diagnosed in a 71-year-old female who presented with a right thigh hematoma of acute onset. The diagnosis was established based on the coagulation profile along with factor VIII levels, mixing studies, and inhibitor levels. The patient received multiple lines of therapy including steroids, factor VIIa, Obizur (porcine-derived recombinant factor VIII), followed by multiple cycles of chemotherapy including cyclophosphamide and rituximab.
    MeSH term(s) Aged ; Antibodies, Monoclonal, Murine-Derived/therapeutic use ; Cyclophosphamide ; Drug Therapy, Combination ; Factor VIII/therapeutic use ; Factor VIIa/therapeutic use ; Female ; Hematoma/blood ; Hematoma/complications ; Hemophilia A/blood ; Hemophilia A/complications ; Hemophilia A/drug therapy ; Humans ; Partial Thromboplastin Time ; Rituximab
    Chemical Substances Antibodies, Monoclonal, Murine-Derived ; Rituximab (4F4X42SYQ6) ; Cyclophosphamide (8N3DW7272P) ; Factor VIII (9001-27-8) ; Factor VIIa (EC 3.4.21.21)
    Language English
    Publishing date 2018-12-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2710326-2
    ISSN 2324-7096 ; 2324-7096
    ISSN (online) 2324-7096
    ISSN 2324-7096
    DOI 10.1177/2324709618817572
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Pain in the Neck - A Case of Intramedullary Spinal Ependymoma.

    Jhaveri, Khushali / Veluru, Manasa / Vakiti, Anusha / Padala, Sandeep A

    Cureus

    2020  Volume 12, Issue 5, Page(s) e7981

    Abstract: Spinal cord tumors are sporadic and account for around 2%-4% of central nervous system neoplasms. Ependymoma is one of the most common spinal cord neoplasms and can present with different neurological signs and symptoms. They commonly present with neck ... ...

    Abstract Spinal cord tumors are sporadic and account for around 2%-4% of central nervous system neoplasms. Ependymoma is one of the most common spinal cord neoplasms and can present with different neurological signs and symptoms. They commonly present with neck or back pain and associated neurological involvement, with sensory symptoms usually antedating the motor symptoms. We now present a rare case of spinal ependymoma in a 26-year-old female who presented with isolated neck pain and the absence of other neurological symptoms. Attention to peculiar characteristics like isolated neck pain might be an essential key to early diagnosis and better prognosis.
    Language English
    Publishing date 2020-05-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.7981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Rare Presentation of Choledochoduodenal Fistula Due to Ovarian Cancer Metastasis.

    Misra, Deeksha / Mirza, Usman / Vakiti, Anusha / Padala, Sandeep Anand

    Journal of investigative medicine high impact case reports

    2020  Volume 8, Page(s) 2324709620934680

    Abstract: Choledochoduodenal fistula (CDF) is an abnormal communication between the common bile duct and the duodenum. It accounts for about 5% to 25% of the total biliary fistulas and is usually due to a perforated duodenal ulcer, choledocholithiasis, and ... ...

    Abstract Choledochoduodenal fistula (CDF) is an abnormal communication between the common bile duct and the duodenum. It accounts for about 5% to 25% of the total biliary fistulas and is usually due to a perforated duodenal ulcer, choledocholithiasis, and complications secondary to tuberculosis or could be iatrogenic. Primary intrabilliary tumors usually cause obstructive jaundice and rarely biliary metastasis arising from other organs like colon, breast, and lungs can cause obstructive jaundice. There has been a case report of metastasis from ovarian cancer to the major papilla of the duodenum but no reported cases of it causing a CDF. We report a rare case of an 83-year-old female with ovarian cancer who developed a metastatic lesion to the duodenum eventually resulting in a CDF.
    MeSH term(s) Aged, 80 and over ; Ampulla of Vater/pathology ; Biliary Fistula/etiology ; Cholangiopancreatography, Endoscopic Retrograde ; Cholangiopancreatography, Magnetic Resonance ; Common Bile Duct/pathology ; Duodenal Neoplasms/physiopathology ; Duodenal Neoplasms/secondary ; Endoscopy, Digestive System ; Female ; Humans ; Intestinal Fistula/etiology ; Ovarian Neoplasms/pathology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2020-06-15
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2710326-2
    ISSN 2324-7096 ; 2324-7096
    ISSN (online) 2324-7096
    ISSN 2324-7096
    DOI 10.1177/2324709620934680
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A Rare Case of Drug-Resistant

    Kapoor, Rajan / Adapa, Sreedhar / Vakiti, Anusha / Gani, Imran Yaseen / Mulloy, Laura / Padala, Sandeep Anand

    Journal of investigative medicine high impact case reports

    2020  Volume 8, Page(s) 2324709620909243

    Abstract: ... Nocardia ... ...

    Abstract Nocardia transvalensis
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Drug Resistance, Multiple, Bacterial ; Humans ; Immunocompromised Host ; Kidney Transplantation ; Nocardia/isolation & purification ; Nocardia Infections/drug therapy ; Nocardia Infections/microbiology ; Opportunistic Infections/complications
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2020-02-15
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2710326-2
    ISSN 2324-7096 ; 2324-7096
    ISSN (online) 2324-7096
    ISSN 2324-7096
    DOI 10.1177/2324709620909243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: First Reported Use of Highly Adsorptive Hemofilter in Critically Ill COVID-19 Patients in the USA.

    Padala, Sandeep Anand / Vakiti, Anusha / White, John Jason / Mulloy, Laura / Mohammed, Azeem

    Journal of clinical medicine research

    2020  Volume 12, Issue 7, Page(s) 454–457

    Abstract: Critically ill patients with coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) develop respiratory failure and septic shock. Extracorporeal blood purification is proposed as an adjuvant therapy for ...

    Abstract Critically ill patients with coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) develop respiratory failure and septic shock. Extracorporeal blood purification is proposed as an adjuvant therapy for sepsis and aims at controlling the dysregulated autoimmune system. We describe our experience in treating COVID-19 patients with the oXiris
    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 2548987-2
    ISSN 1918-3011 ; 1918-3003
    ISSN (online) 1918-3011
    ISSN 1918-3003
    DOI 10.14740/jocmr4228
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Rectovaginal Fistula as a Complication of Fecal Management System.

    Butts, Emily / Padala, Sandeep Anand / Vakiti, Anusha / Kota, Vamsi

    Journal of investigative medicine high impact case reports

    2019  Volume 7, Page(s) 2324709619869368

    Abstract: We report a rare complication of the use of an intrarectal catheter. An 18-year-old female with T-cell acute lymphoblastic leukemia post-matched unrelated donor allogeneic stem cell transplantation (auto-SCT) developed hepatic encephalopathy secondary to ...

    Abstract We report a rare complication of the use of an intrarectal catheter. An 18-year-old female with T-cell acute lymphoblastic leukemia post-matched unrelated donor allogeneic stem cell transplantation (auto-SCT) developed hepatic encephalopathy secondary to hepatic sinusoidal obstructive disease. A fecal management system was used to contain and divert fecal matter in this immobilized patient. Approximately 1 month after placement of an intrarectal catheter, stool was noted in the vaginal vault. Speculum examination confirmed development of a rectovaginal fistula.
    MeSH term(s) Adolescent ; Catheterization/adverse effects ; Catheters/adverse effects ; Fatal Outcome ; Female ; Graft Rejection/complications ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Multiple Organ Failure/etiology ; Multiple Organ Failure/therapy ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/complications ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/therapy ; Rectovaginal Fistula/etiology ; Rectum
    Language English
    Publishing date 2019-08-18
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2710326-2
    ISSN 2324-7096 ; 2324-7096
    ISSN (online) 2324-7096
    ISSN 2324-7096
    DOI 10.1177/2324709619869368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Management of Immunosuppression During Severe COVID-19 Infection in a Patient With Pulmonary and Cardiac Sarcoidosis.

    Padala, Sandeep A / Medepalli, Vidya M / Mohammed, Azeem / Vakiti, Anusha / Elam, Rachel / Gupta, Sandeep J

    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

    2020  Volume 26, Issue 6, Page(s) 229–232

    MeSH term(s) Betacoronavirus ; COVID-19 ; Cardiomyopathies/complications ; Cardiomyopathies/drug therapy ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Female ; Humans ; Immunosuppressive Agents/administration & dosage ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; Sarcoidosis, Pulmonary/complications ; Sarcoidosis, Pulmonary/drug therapy
    Chemical Substances Immunosuppressive Agents
    Keywords covid19
    Language English
    Publishing date 2020-07-31
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1283266-2
    ISSN 1536-7355 ; 1076-1608
    ISSN (online) 1536-7355
    ISSN 1076-1608
    DOI 10.1097/RHU.0000000000001557
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4815: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Hemophagocytic Lymphohistiocytosis Secondary to Bone Marrow Only B-Cell Lymphoma: A Very Rare Entity With an Even Rarer Presentation.

    Patel, Ami / Vakiti, Anusha / Chilkulwar, Abhishek / Mewawalla, Prerna

    Journal of hematology

    2017  Volume 6, Issue 2-3, Page(s) 49–51

    Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome. It is categorized as familial or acquired, most commonly caused by infections, malignancies, rheumatologic and immunodeficiency disorders. Irrespective of the etiology, the ... ...

    Abstract Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome. It is categorized as familial or acquired, most commonly caused by infections, malignancies, rheumatologic and immunodeficiency disorders. Irrespective of the etiology, the age at the onset is the strongest prognostic factor, hence it is extremely important to have a high suspicion for HLH, diagnose it promptly and initiate treatment without any delay. We encountered a 70-year-old female patient who initially presented with left-sided facial weakness and pancytopenia, secondary to diffuse stage IV B diffuse large B-cell lymphoma with isolated bone marrow involvement with secondary HLH.
    Language English
    Publishing date 2017-07-20
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 2662519-2
    ISSN 1927-1220 ; 1927-1212
    ISSN (online) 1927-1220
    ISSN 1927-1212
    DOI 10.14740/jh324w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Acquired Hemophilia A Presenting as Intramuscular Hematoma

    Ghassan Al-Shbool MD / Anusha Vakiti MD

    Journal of Investigative Medicine High Impact Case Reports, Vol

    2018  Volume 6

    Abstract: Acquired hemophilia A poses a clinical and diagnostic challenge. Although rare, it is still the most common acquired factor deficiency. We present a case of acquired hemophilia A diagnosed in a 71-year-old female who presented with a right thigh hematoma ...

    Abstract Acquired hemophilia A poses a clinical and diagnostic challenge. Although rare, it is still the most common acquired factor deficiency. We present a case of acquired hemophilia A diagnosed in a 71-year-old female who presented with a right thigh hematoma of acute onset. The diagnosis was established based on the coagulation profile along with factor VIII levels, mixing studies, and inhibitor levels. The patient received multiple lines of therapy including steroids, factor VIIa, Obizur (porcine-derived recombinant factor VIII), followed by multiple cycles of chemotherapy including cyclophosphamide and rituximab.
    Keywords Medicine (General) ; R5-920 ; Pathology ; RB1-214
    Language English
    Publishing date 2018-12-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Efficacy and Safety of Direct-Acting Oral Anticoagulants (DOACs) in the Overweight and Obese.

    Doucette, Kimberley / Latif, Hira / Vakiti, Anusha / Tefera, Eshetu / Patel, Bhavisha / Fitzpatrick, Kelly

    Advances in hematology

    2020  Volume 2020, Page(s) 3890706

    Abstract: Obesity plays an essential role in the safety of pharmacologic drugs. There is paucity of data for direct oral anticoagulants (DOACs) in the obese, despite these agents becoming more widely used. The primary and secondary objectives of this study were to ...

    Abstract Obesity plays an essential role in the safety of pharmacologic drugs. There is paucity of data for direct oral anticoagulants (DOACs) in the obese, despite these agents becoming more widely used. The primary and secondary objectives of this study were to assess the safety and efficacy of DOACs in the overweight and obese populations when used for primary prophylaxis in the setting of non-valvular atrial fibrillation (NVAF) and for treatment of venous thromboembolisms (VTE). We conducted a retrospective cohort study in a large tertiary care center and obtained data through review of electronic health records. Among patients with NVAF and VTE on apixaban, there were no differences in rates of major bleeding (MB) and clinically relevant nonmajor bleeding (CRNMB) in the overweight and obese populations when compared to normal weight and underweight individuals. The multivariate adjusted analysis for rivaroxaban found that the odds of CRNMB for patients with BMI <25 was 5.37 (95% CI 1.50-19.32) times higher than that of BMI ≥25. Moreover, patients on medications that had known interactions with DOACs had 6.40 times higher odds of CRNMB than patients without such interactions (95% CI 1.49-27.57), which was not accounted for by the effects of aspirin and plavix alone. Efficacy was similar between all weight groups, for both apixaban and rivaroxaban. These results support previous analyses preformed in the large phase III trials and confirm that apixaban and rivaroxaban are safe in the overweight and obese.
    Language English
    Publishing date 2020-05-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2494501-8
    ISSN 1687-9112 ; 1687-9104
    ISSN (online) 1687-9112
    ISSN 1687-9104
    DOI 10.1155/2020/3890706
    Database MEDical Literature Analysis and Retrieval System OnLINE

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