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  1. Article: Pseudotumor Cerebri Presenting by Neck Rigidity and Torticollis.

    Hassanzadeh Rad, Afagh / Aminzadeh, Vahid

    Iranian journal of child neurology

    2023  Volume 17, Issue 1, Page(s) 119–123

    Abstract: Pseudotumor cerebri syndrome (PTCS) is an uncommon disease in children. On-time diagnosis and treatment can prevent irreversible visual loss. Although headache is the most common complaint of children with this syndrome, the present case report reported ... ...

    Abstract Pseudotumor cerebri syndrome (PTCS) is an uncommon disease in children. On-time diagnosis and treatment can prevent irreversible visual loss. Although headache is the most common complaint of children with this syndrome, the present case report reported a child with neck rigidity and torticollis, declined by the reduction of intracranial pressure. Despite the importance of torticollis and neck rigidity presented in various significant neurological disorders in need of thorough investigations, in the case of unexplained symptoms of those disorders, it is recommended to consider fundoscopic examinations for PTCS to prevent its vital complications.
    Language English
    Publishing date 2023-01-01
    Publishing country Iran
    Document type Case Reports
    ZDB-ID 2542305-8
    ISSN 2008-0700 ; 1735-4668
    ISSN (online) 2008-0700
    ISSN 1735-4668
    DOI 10.22037/ijcn.v17i1.32415
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The Consensus on the Diagnosis and Management of Congenital Hypothyroidism in Term Neonates.

    Hashemipour, Mahin / Rabbani, Ali / Rad, Afagh Hassanzadeh / Dalili, Setila

    International journal of preventive medicine

    2023  Volume 14, Page(s) 11

    Abstract: Congenital hypothyroidism (CH) is one of the most treatable endocrine disorders in infants and children that can influence the function of many organs in the body. On-time diagnosis and treatment can prevent the adverse effects of thyroid hormone ... ...

    Abstract Congenital hypothyroidism (CH) is one of the most treatable endocrine disorders in infants and children that can influence the function of many organs in the body. On-time diagnosis and treatment can prevent the adverse effects of thyroid hormone deficiency on the child's neurodevelopment. There are many challenges in screening, post-screening, diagnosis, and managing this disorder. Therefore, this article aimed to mention updated information on this issue. Although there are different approaches for the treatment of hypothyroidism, the authors decided to create a national approach based on the conditions of our country.
    Language English
    Publishing date 2023-01-25
    Publishing country Iran
    Document type Journal Article ; Review
    ZDB-ID 2574680-7
    ISSN 2008-8213 ; 2008-7802
    ISSN (online) 2008-8213
    ISSN 2008-7802
    DOI 10.4103/ijpvm.ijpvm_535_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Effect of Probiotics on Headaches in Children with Migraine Treated with Sodium Valproate: A Randomized Controlled Clinical Trial.

    Bidabadi, Elham / Elyasi, Mitra / Hassanzadeh Rad, Afagh / Kazemnezhad, Ehsan

    Iranian journal of child neurology

    2023  Volume 17, Issue 2, Page(s) 119–126

    Abstract: Objective: Migraine is one of the most common complaints in children. This study aimed to determine the effect of probiotics (KidiLact) on headaches in children aged six to 15 years with migraine treated with sodium valproate.: Materials & methods: ... ...

    Abstract Objective: Migraine is one of the most common complaints in children. This study aimed to determine the effect of probiotics (KidiLact) on headaches in children aged six to 15 years with migraine treated with sodium valproate.
    Materials & methods: This double-blind, randomized controlled clinical trial was performed on eighty children with migraine treated with sodium valproate. Patients were divided into two groups. All patients in the intervention and control groups received two sachets of probiotics and a placebo daily for four months, respectively. They were compared in terms of frequency and severity of headaches and painkiller consumption before and two and four months after initiating probiotics.
    Results: The mean number of headaches in the second and third visits in the probiotic group was 1.27 and 1.18, and 2 and 1.50 per month in the placebo group, respectively. The authors observed a significant difference between the two groups in the second (P = 0.010) and the third visit (P = 0.019). Moreover, the mean severity of headache in the second and third visits in the probiotic group was 1.38 and 1.23, and 1.60 and 1.53 in the placebo group, respectively. The authors demonstrated that the daily consumption of painkillers in the probiotic group was significantly reduced compared to the placebo group (P = 0.007).
    Conclusion: Using probiotic supplements seems to significantly affect the severity and frequency of migraine headaches compared to the placebo, and daily consumption of painkillers was significantly reduced in the probiotic group compared to the placebo group.
    Language English
    Publishing date 2023-03-15
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2542305-8
    ISSN 2008-0700 ; 1735-4668
    ISSN (online) 2008-0700
    ISSN 1735-4668
    DOI 10.22037/ijcn.v17i2.40369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The consensus on the diagnosis and management of congenital 2 hypothyroidism in term neonates

    Mahin Hashemipour / Ali Rabbani / Afagh Hassanzadeh Rad / Setila Dalili

    International Journal of Preventive Medicine, Vol 14, Iss 1, Pp 11-

    2023  Volume 11

    Abstract: Congenital hypothyroidism (CH) is one of the most treatable endocrine disorders in infants and children that can influence the function of many organs in the body. On-time diagnosis and treatment can prevent the adverse effects of thyroid hormone ... ...

    Abstract Congenital hypothyroidism (CH) is one of the most treatable endocrine disorders in infants and children that can influence the function of many organs in the body. On-time diagnosis and treatment can prevent the adverse effects of thyroid hormone deficiency on the child's neurodevelopment. There are many challenges in screening, post-screening, diagnosis, and managing this disorder. Therefore, this article aimed to mention updated information on this issue. Although there are different approaches for the treatment of hypothyroidism, the authors decided to create a national approach based on the conditions of our country.
    Keywords congenital hypothyroidism ; infant ; newborn ; Medicine ; R
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Micronutrients in infants suffering from cow's milk allergy fed with dietary formulas and breast milk.

    Maleknejad, Shohreh / Dashti, Kobra / Safaei-Asl, Afshin / Roshan, Zahra Atrkar / Salehi, Soodeh / Hassanzadeh-Rad, Afagh

    BMC pediatrics

    2024  Volume 24, Issue 1, Page(s) 115

    Abstract: Introduction: Cow's milk allergy (CMA) is the most common food allergy in infants. As this food allergy indicates a wide range of clinical syndromes due to immunological reactions to cow's milk proteins, we aimed to evaluate the status of micronutrients ...

    Abstract Introduction: Cow's milk allergy (CMA) is the most common food allergy in infants. As this food allergy indicates a wide range of clinical syndromes due to immunological reactions to cow's milk proteins, we aimed to evaluate the status of micronutrients in infants suffering from cow's milk allergy.
    Methods: In this historical cohort study, infants with CMA were divided into two equal groups: breastfeeding and diet formula feeding. Data were gathered by a form, including the micronutrients such as iron, selenium, calcium, phosphorus, zinc, and vitamin D. Groups were compared and data were analyzed by the IBM SPSS version 21.
    Results: This study involved 60 six-month-old infants, and the findings revealed no significant difference between the two groups concerning magnesium, phosphorus, zinc, and vitamin D. However, infants in the formula-feeding group exhibited significantly elevated mean serum levels of iron and selenium, whereas breastfed infants displayed higher levels of calcium.
    Conclusion: The findings of this research revealed a significant difference in calcium, selenium, and iron levels between formula-fed and breastfed infants, even though all variables were within the normal range for both groups. In light of these results, conducting further studies with a larger sample size and extended follow-up periods becomes imperative.
    MeSH term(s) Infant ; Female ; Animals ; Cattle ; Humans ; Milk Hypersensitivity ; Milk, Human ; Cohort Studies ; Micronutrients ; Selenium ; Calcium ; Food Hypersensitivity ; Diet ; Breast Feeding ; Vitamin D ; Iron ; Phosphorus ; Zinc
    Chemical Substances Micronutrients ; Selenium (H6241UJ22B) ; Calcium (SY7Q814VUP) ; Vitamin D (1406-16-2) ; Iron (E1UOL152H7) ; Phosphorus (27YLU75U4W) ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-024-04591-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Guideline for the Treatment of Hypothyroidism in Prematurity.

    Hashemipour, Mahin / Rad, Afagh Hassanzadeh / Dalili, Setila

    International journal of preventive medicine

    2021  Volume 12, Page(s) 123

    Abstract: Congenital hypothyroidism is one of the most common endocrine disorders in infants and children. Thyroid hormone effects the function of most organs of the body. In premature neonates, thyroid abnormalities are very common but transient. There is a ... ...

    Abstract Congenital hypothyroidism is one of the most common endocrine disorders in infants and children. Thyroid hormone effects the function of most organs of the body. In premature neonates, thyroid abnormalities are very common but transient. There is a significant difference between the appropriate time for screening in premature and term neonates and there are different viewpoints in treating hypothyroidism in prematurity. According to the probable exceptions in this issue, there is no definite guideline. Therefore, regarding this confusion, this guideline aimed to help clinicians for rapid on-time decision making.
    Language English
    Publishing date 2021-09-29
    Publishing country Iran
    Document type Journal Article ; Review
    ZDB-ID 2574680-7
    ISSN 2008-8213 ; 2008-7802
    ISSN (online) 2008-8213
    ISSN 2008-7802
    DOI 10.4103/ijpvm.IJPVM_424_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Simple Memorable Formulas for Screening Hypertension in Children: Based on the New American Academy of Pediatrics Guideline.

    Hassanzadeh Rad, Afagh / Kamalpour, Jahangir / Badeli, Behrad / Badeli, Daniel / Badeli, Hamidreza

    Iranian journal of kidney diseases

    2023  Volume 17, Issue 6, Page(s) 306–313

    Abstract: Introduction: Hypertension (HTN), also known as high blood pressure (BP), is a major global risk factor for cardiovascular and kidney diseases. Although annual BP screenings for children over three years of age are recommended, underdiagnosis of HTN in ... ...

    Abstract Introduction: Hypertension (HTN), also known as high blood pressure (BP), is a major global risk factor for cardiovascular and kidney diseases. Although annual BP screenings for children over three years of age are recommended, underdiagnosis of HTN in children is common. To address this issue, the American Academy of Pediatrics updated its guideline for screening and managing high BP in children in 2017, which can be cumbersome to implement in clinical practice due to the numerous cut-off points and tables. The purpose of our study is to design formulas to detect HTN in children based on the new Clinical Practice Guideline for screening and management of high BP in children and adolescents.
    Methods: In this research, we analyzed forty-eight cut-off points using the 90th percentile systolic and diastolic BPs for the fifth percentile height. The final mathematical model consisted of four formulas based on different ages and sex which in turn were rounded by 0.1 and 1.0 for both systolic and diastolic BPs. The formulas were further modified to be lower than the 95th percentile systolic BPs for the fifth percentile of height to minimize false negative results.
    Results: As evidenced by the tables included in this paper, except for a few exceptions, all rounded systolic and diastolic values for both sexes were equal to or lower than the 90th percentile. In a few cases where the cutoff points calculated by the formula were higher than the ones provided in the 2017 guideline, the differences were less than 2 mmHg.
    Conclusion: In this study to address the complexity of the routine guidelines, we present simplified formulas for screening children aged 1 to 12 years in figures and tables and recommend their use, particularly in office and emergency settings, as an easier-to-implement first step in screening for HTN in children.  DOI: 10.52547/ijkd.7525.
    MeSH term(s) Male ; Adolescent ; Female ; Humans ; Child ; United States ; Child, Preschool ; Hypertension/etiology ; Mass Screening/adverse effects ; Mass Screening/methods ; Risk Factors ; Blood Pressure
    Language English
    Publishing date 2023-12-03
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2388271-2
    ISSN 1735-8604 ; 1735-8582
    ISSN (online) 1735-8604
    ISSN 1735-8582
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effect of concurrent resistance-aerobic training on inflammatory factors and growth hormones in children with type 1 diabetes: a randomized controlled clinical trial.

    Nazari, Marzieh / Shabani, Ramin / Hassanzadeh-Rad, Afagh / Esfandiari, Mohammad Ali / Dalili, Setila

    Trials

    2023  Volume 24, Issue 1, Page(s) 519

    Abstract: Background: Exercise training is a major factor in controlling type 1 diabetes mellitus (T1DM) in children. The present study aimed to assess the effect of concurrent resistance-aerobic training on selected inflammatory factors and hormones related to ... ...

    Abstract Background: Exercise training is a major factor in controlling type 1 diabetes mellitus (T1DM) in children. The present study aimed to assess the effect of concurrent resistance-aerobic training on selected inflammatory factors and hormones related to blood glucose homeostasis in children with T1DM.
    Methods: In this randomized controlled clinical trial, 40 children (with the mean age of 11.11 ± 2.29 years) were randomly assigned to an experimental (N = 20) or control group (N = 20). They underwent a 16-week training program, composed of concurrent resistance-aerobic training performed intermittently for 60 min three times a week. Before and after training, blood samples were analyzed for glucose homeostasis, selected inflammatory factors, and growth factors. Data were analyzed by paired t-test and analysis of covariance (ANCOVA) in IBM SPSS version 22.
    Results: The exercise training intervention reduced fasting blood sugar index (P = 0.002) and glycosylated hemoglobin significantly (P = 0.003). The growth hormone levels were increased significantly only in the experimental group (P = 0.037), whereas no significant difference was noted in the insulin-like growth factor-1 (P = 0.712). It was also found that interleukin-1β and high-sensitivity C-reactive protein did not change in the experimental or control group as compared to the pretest (P > 0.05).
    Conclusion: As it was shown, it seems that concurrent resistance-aerobic training may improve blood glucose homeostasis and growth hormone. Therefore, these findings may suggest the benefit from exercise training of moderate intensity in children with T1DM. Besides, we recommend undertaking further clinical trials to determine if the exercise training was effective.
    Trial registration: This study was registered in the Iranian Registry of Clinical Trials under the code IRCT20150531022498N30: https://en.irct.ir/trial/41031 . Registered on July 26, 2019. All experiments on the participants were following the Declaration of Helsinki.
    MeSH term(s) Humans ; Child ; Adolescent ; Diabetes Mellitus, Type 1/diagnosis ; Diabetes Mellitus, Type 1/therapy ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 2 ; Iran ; Growth Hormone
    Chemical Substances Blood Glucose ; Growth Hormone (9002-72-6)
    Language English
    Publishing date 2023-08-12
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-023-07553-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Guideline for the treatment of hypothyroidism in prematurity

    Mahin Hashemipour / Afagh Hassanzadeh Rad / Setila Dalili

    International Journal of Preventive Medicine, Vol 12, Iss 1, Pp 123-

    2021  Volume 123

    Abstract: Congenital hypothyroidism is one of the most common endocrine disorders in infants and children. Thyroid hormone effects the function of most organs of the body. In premature neonates, thyroid abnormalities are very common but transient. There is a ... ...

    Abstract Congenital hypothyroidism is one of the most common endocrine disorders in infants and children. Thyroid hormone effects the function of most organs of the body. In premature neonates, thyroid abnormalities are very common but transient. There is a significant difference between the appropriate time for screening in premature and term neonates and there are different viewpoints in treating hypothyroidism in prematurity. According to the probable exceptions in this issue, there is no definite guideline. Therefore, regarding this confusion, this guideline aimed to help clinicians for rapid on-time decision making.
    Keywords hypothyroidism ; infant ; premature birth ; Medicine ; R
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Evaluation of therapeutic effect of oral Ursodeoxycholic Acid on indirect hyperbilirubinemia in term neonates undergoing phototherapy

    Marjaneh Zarkesh / Sadroddin Mahdipour / Safoora Aghili / Atefeh Jafari / Seyyedeh Azadeh Hoseini Nouri / Afagh Hassanzadeh Rad / Maryam Ghalandari / Manijeh Tabrizi

    PLoS ONE, Vol 18, Iss

    A randomized controlled clinical trial

    2023  Volume 12

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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