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Article ; Online: Breastfeeding Initiation in People With Hepatitis C Virus Infection in the United States.

Blauvelt, Christine A / Turcios, Stephanie / Wen, Timothy / Boscardin, John / Seidman, Dominika

2024 Volume 143, Issue 5, Page(s) 683–689

Abstract: Objective: To evaluate breastfeeding initiation rates among people living with and without hepatitis C virus (HCV) infection during pregnancy and to identify characteristics associated with breastfeeding initiation.: Methods: We conducted a cross- ... ...

Abstract	Objective: To evaluate breastfeeding initiation rates among people living with and without hepatitis C virus (HCV) infection during pregnancy and to identify characteristics associated with breastfeeding initiation. Methods: We conducted a cross-sectional analysis of individuals who had a live birth in the United States from 2016 to 2021 using the National Center for Health Statistics birth certificate data. We grouped participants by whether they had HCV infection during pregnancy. Using propensity-score matching, we assessed the association between breastfeeding initiation before hospital discharge , defined as neonates receiving any parental breast milk or colostrum, and HCV infection during pregnancy in a logistic regression model. We also assessed factors associated with breastfeeding initiation among those with HCV infection. Results: There were 96,896 reported cases (0.5%) of HCV infection among 19.0 million births that met inclusion criteria during the study period. Using propensity-score matching, we matched 87,761 individuals with HCV infection during pregnancy with 87,761 individuals without HCV infection. People with HCV infection during pregnancy were less likely to initiate breastfeeding compared with those without HCV infection (51.5% vs 64.2%, respectively; odds ratio 0.59, 95% CI, 0.58-0.60, P <.001). Characteristics associated with higher rates of breastfeeding initiation among individuals with HCV infection included a college degree (adjusted odds ratio [aOR] 1.22, 95% CI, 1.21-1.24); self-identified race or ethnicity as Native Hawaiian or Pacific Islander (aOR 1.22, 95% CI, 1.06-1.40), Asian (aOR 1.09, 95% CI, 1.06-1.13), or Hispanic (aOR 1.09, 95% CI, 1.08-1.11); private insurance (aOR 1.07, 95% CI, 1.06-1.08); nulliparity (aOR 1.09, 95% CI, 1.08-1.10), and being married (aOR 1.08, 95% CI, 1.07-1.09). Characteristics associated with not breastfeeding before hospital discharge included receiving no prenatal care (aOR 0.81, 95% CI, 0.79-0.82), smoking during pregnancy (aOR 0.88, 95% CI, 0.88-0.89), and neonatal intensive care unit admission (aOR 0.92, 95% CI, 0.91-0.93). Conclusion: Despite leading health organizations' support for people living with HCV infection to breastfeed, our study demonstrates low breastfeeding initiation rates in this population. Our findings highlight the need for tailored breastfeeding support for people with HCV infection and for understanding the additional effects of human immunodeficiency virus (HIV) co-infection, HCV treatment, and concurrent substance use disorders on breastfeeding initiation.
MeSH term(s)	Pregnancy ; Infant, Newborn ; Female ; Humans ; United States/epidemiology ; Hepacivirus ; Breast Feeding ; Cross-Sectional Studies ; Hepatitis C/epidemiology ; Hepatitis C/complications ; HIV Infections/complications
Language	English
Publishing date	2024-03-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	207330-4
ISSN	1873-233X ; 0029-7844
ISSN (online)	1873-233X
ISSN	0029-7844
DOI	10.1097/AOG.0000000000005555
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Article ; Online: Trends in attempted vaginal delivery among pregnancies complicated by fetal myelomeningocele in the United States.

Blauvelt, Christine A / Sobhani, Nasim C / Andrikopoulou, Maria / Friedman, Alexander M / Gonzalez-Velez, Juan M / Wen, Timothy

American journal of obstetrics & gynecology MFM

2023 Volume 5, Issue 4, Page(s) 100902

MeSH term(s)	Pregnancy ; Female ; United States/epidemiology ; Humans ; Meningomyelocele/diagnosis ; Meningomyelocele/epidemiology ; Meningomyelocele/surgery ; Delivery, Obstetric ; Cesarean Section ; Prenatal Care
Language	English
Publishing date	2023-02-10
Publishing country	United States
Document type	Letter
ISSN	2589-9333
ISSN (online)	2589-9333
DOI	10.1016/j.ajogmf.2023.100902
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Corrigendum to Trends in attempted vaginal delivery among pregnancies complicated by fetal myelomeningocele in the United States. American Journal of Obstetrics & Gynecology MFM. Volume 5, Issue 4, April 2023, 100902.

Blauvelt, Christine A / Sobhani, Nasim C / Andrikopoulou, Maria / Friedman, Alexander M / Gonzalez-Velez, Juan M / Wen, Timothy

American journal of obstetrics & gynecology MFM

2023 Volume 5, Issue 6, Page(s) 100975

Language	English
Publishing date	2023-05-03
Publishing country	United States
Document type	Published Erratum
ISSN	2589-9333
ISSN (online)	2589-9333
DOI	10.1016/j.ajogmf.2023.100975
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Article ; Online: Perinatal Outcomes Among Patients With Sepsis During Pregnancy.

Blauvelt, Christine A / Nguyen, Kiana C / Cassidy, Arianna G / Gaw, Stephanie L

JAMA network open

2021 Volume 4, Issue 9, Page(s) e2124109

Abstract: Importance: Rates of maternal sepsis are increasing, and prior studies of maternal sepsis have focused on immediate maternal morbidity and mortality associated with sepsis during delivery admission. There are no data on pregnancy outcomes among ... ...

Abstract	Importance: Rates of maternal sepsis are increasing, and prior studies of maternal sepsis have focused on immediate maternal morbidity and mortality associated with sepsis during delivery admission. There are no data on pregnancy outcomes among individuals who recover from their infections prior to delivery. Objective: To describe perinatal outcomes among patients with antepartum sepsis who did not deliver during their infection hospitalization. Design, setting, and participants: This retrospective cohort study was conducted using data from August 1, 2012, to August 1, 2018, at an academic referral center in San Francisco, California. Included patients were all individuals with nonanomalous, singleton pregnancies who delivered after 20 weeks' gestation during the study period. Data were analyzed from March 2020 through March 2021. Exposures: Antepartum admission for infection with clinical concern for sepsis and hospital discharge prior to delivery. Main outcomes and measures: The primary outcome was a composite of perinatal outcomes associated with placental dysfunction and consisted of 1 or more of the following: fetal growth restriction, oligohydramnios, hypertensive disease of pregnancy, cesarean delivery for fetal indication, child who is small for gestational age, or stillbirth. Results: Among 14 565 patients with nonanomalous singleton pregnancies (mean [SD] age at delivery, 33.1 [5.2] years), 59 individuals (0.4%) were in the sepsis group and 14 506 individuals (99.6%) were in the nonsepsis group; 8533 individuals (59.0%) were nulliparous. Patients with sepsis, compared with patients in the reference group, were younger (mean [SD] age at delivery, 30.6 [5.7] years vs 33.1 [5.2] years; P < .001), were more likely to have pregestational diabetes (5 individuals [8.5%] vs 233 individuals [1.6%]; P = .003), and had higher mean (SD) pregestational body mass index scores (26.1 [6.1] vs 24.4 [5.9]; P = .03). In the sepsis group, the most common infections were urinary tract infections (24 patients [40.7%]) and pulmonary infections (22 patients [37.3%]). Among patients with sepsis, 5 individuals (8.5%) were admitted to the intensive care unit, the mean (SD) gestational age at infection was 24.6 (9.0) weeks, and the median (interquartile range) time from infection to delivery was 82 (42-147) days. Antepartum sepsis was associated with higher odds of placental dysfunction (21 patients [35.6%] vs 3450 patients [23.8%]; odds ratio, 1.77; 95% CI, 1.04-3.02; P = .04). On multivariable logistic regression analysis, antepartum sepsis was an independent factor associated with placental dysfunction (adjusted odds ratio, 1.88; 95% CI, 1.10-3.23; P = .02) after adjusting for possible confounders. Conclusions and relevance: This study found that pregnancies complicated by antepartum sepsis were associated with higher odds of placental dysfunction. These findings suggest that increased antenatal surveillance should be considered for these patients.
MeSH term(s)	Adult ; California/epidemiology ; Female ; Humans ; Infant, Newborn ; Male ; Pregnancy ; Pregnancy Complications, Infectious ; Pregnancy Outcome ; Prenatal Care ; Stillbirth/epidemiology
Language	English
Publishing date	2021-09-01
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ISSN	2574-3805
ISSN (online)	2574-3805
DOI	10.1001/jamanetworkopen.2021.24109
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effectiveness of antepartum intravenous iron sucrose: dose timing and impact on outcomes.

Hamm, Rebecca F / Blauvelt, Christine / Wang, Eileen Y / Srinivas, Sindhu K

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

2019 Volume 34, Issue 12, Page(s) 1983–1990

Abstract: Objective: Studies have demonstrated that antepartum intravenous iron sucrose infusion (IVFe) is safe and improves predelivery hemoglobin (Hb). Yet, there is little data guiding timing of administration or number of doses required to be impactful. We ... ...

Abstract	Objective: Studies have demonstrated that antepartum intravenous iron sucrose infusion (IVFe) is safe and improves predelivery hemoglobin (Hb). Yet, there is little data guiding timing of administration or number of doses required to be impactful. We sought to determine if timing of antepartum IVFe and number of doses provided impacts efficacy. Methods: We performed a retrospective cohort study of women who obtained prenatal care and delivered at our institution 10/1/2015-10/30/2017. Women with a third-trimester hemoglobin (Hb) < 9.5 g/dL were included. Women with hemoglobinopathies and those who received an antepartum blood transfusion were excluded. Women receiving ≥1 antepartum 300 mg IVFe dose were considered in the IVFe group. Results: Five-hundred-twenty-three (6.1%) of 8563 delivering women were included. Sixty-five (12.4%) of included women received IVFe. By timing of IVFe, the earlier IVFe was received before delivery, the greater the median Hb increase (No IVFe: Δ0.8g/dL, IVFe 0-1 weeks predelivery: Δ0.05 g/dL, 1-2 weeks: Δ0.9 g/dL, 2-4 weeks: Δ1.5 g/dL, 4-6 weeks: Δ1.8 g/dL, 6-8 weeks: Δ1.8 g/dL, 8-12 weeks: Δ2.75 g/dL, Conclusion: Antepartum IVFe effectively increases Hb from the third trimester to delivery admission when administered 2-12 weeks predelivery. There is increasing benefit the further out the IVFe is administered and with an increasing number of doses. Initiatives to combat antepartum anemia should focus on early detection and treatment to best optimize outcomes.
MeSH term(s)	Anemia ; Anemia, Iron-Deficiency ; Female ; Ferric Compounds ; Ferric Oxide, Saccharated ; Hemoglobins/analysis ; Humans ; Pregnancy ; Retrospective Studies
Chemical Substances	Ferric Compounds ; Hemoglobins ; Ferric Oxide, Saccharated (FZ7NYF5N8L)
Language	English
Publishing date	2019-08-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2077261-0
ISSN	1476-4954 ; 1057-0802 ; 1476-7058
ISSN (online)	1476-4954
ISSN	1057-0802 ; 1476-7058
DOI	10.1080/14767058.2019.1656189
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Article ; Online: Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19).

Blauvelt, Christine A / Chiu, Catherine / Donovan, Anne L / Prahl, Mary / Shimotake, Thomas K / George, Ronald B / Schwartz, Brian S / Farooqi, Naghma A / Ali, Syed S / Cassidy, Arianna / Gonzalez, Juan M / Gaw, Stephanie L

Obstetrics and gynecology

2020 Volume 136, Issue 1, Page(s) 46–51

Abstract: Background: Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant ... ...

Abstract	Background: Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant patients who are critically ill with coronavirus disease 2019 (COVID-19) infection is complicated by physiologic changes and other pregnancy considerations and requires balancing maternal and fetal well-being. Case: We report the case of a patient at 28 weeks of gestation with acute respiratory distress syndrome (ARDS) from COVID-19 infection, whose deteriorating respiratory condition prompted delivery. Our patient's oxygenation and respiratory mechanics improved within hours of delivery, though she required prolonged mechanical ventilation until postpartum day 10. Neonatal swabs for SARS-CoV-2 and COVID-19 immunoglobulin (Ig) G and IgM were negative. Conclusion: We describe our multidisciplinary management of a preterm pregnant patient with ARDS from COVID-19 infection and her neonate.
MeSH term(s)	Adult ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/therapy ; Coronavirus Infections/virology ; Female ; Humans ; Infant, Newborn ; Live Birth ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/therapy ; Pneumonia, Viral/virology ; Pregnancy ; Pregnancy Complications, Infectious/therapy ; Pregnancy Complications, Infectious/virology ; Premature Birth/therapy ; Premature Birth/virology ; Respiration, Artificial/methods ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-04-09
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	207330-4
ISSN	1873-233X ; 0029-7844
ISSN (online)	1873-233X
ISSN	0029-7844
DOI	10.1097/AOG.0000000000003949
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Article ; Online: Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19)

Blauvelt, Christine A. / Chiu, Catherine / Donovan, Anne L. / Prahl, Mary / Shimotake, Thomas K. / George, Ronald B. / Schwartz, Brian S. / Farooqi, Naghma A. / Ali, Syed S. / Cassidy, Arianna / Gonzalez, Juan M. / Gaw, Stephanie L.

Obstetrics & Gynecology

2020 Volume Publish Ahead of Print

Keywords	Obstetrics and Gynaecology ; covid19
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publishing country	us
Document type	Article ; Online
ZDB-ID	207330-4
ISSN	1873-233X ; 0029-7844
ISSN (online)	1873-233X
ISSN	0029-7844
DOI	10.1097/aog.0000000000003949
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19)

Obstet Gynecol

Abstract: BACKGROUND: Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant ... ...

Abstract	BACKGROUND: Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant patients who are critically ill with coronavirus disease 2019 (COVID-19) infection is complicated by physiologic changes and other pregnancy considerations and requires balancing maternal and fetal well-being. CASE: We report the case of a patient at 28 weeks of gestation with acute respiratory distress syndrome (ARDS) from COVID-19 infection, whose deteriorating respiratory condition prompted delivery. Our patient's oxygenation and respiratory mechanics improved within hours of delivery, though she required prolonged mechanical ventilation until postpartum day 10. Neonatal swabs for SARS-CoV-2 and COVID-19 immunoglobulin (Ig) G and IgM were negative. CONCLUSION: We describe our multidisciplinary management of a preterm pregnant patient with ARDS from COVID-19 infection and her neonate.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #197237
Database	COVID19

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Article ; Online: Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19).

Obstetrics and gynecology, vol 136, iss 1

2020

Abstract: BACKGROUND:Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant ... ...

Abstract	BACKGROUND:Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant patients who are critically ill with coronavirus disease 2019 (COVID-19) infection is complicated by physiologic changes and other pregnancy considerations and requires balancing maternal and fetal well-being. CASE:We report the case of a patient at 28 weeks of gestation with acute respiratory distress syndrome (ARDS) from COVID-19 infection, whose deteriorating respiratory condition prompted delivery. Our patient's oxygenation and respiratory mechanics improved within hours of delivery, though she required prolonged mechanical ventilation until postpartum day 10. Neonatal swabs for SARS-CoV-2 and COVID-19 immunoglobulin (Ig) G and IgM were negative. CONCLUSION:We describe our multidisciplinary management of a preterm pregnant patient with ARDS from COVID-19 infection and her neonate.
Keywords	Adult ; Betacoronavirus ; Coronavirus Infections ; Female ; Humans ; Infant ; Newborn ; Live Birth ; Pandemics ; Pneumonia ; Viral ; Pregnancy ; Pregnancy Complications ; Infectious ; Premature Birth ; Respiration ; Artificial ; Obstetrics & Reproductive Medicine ; Paediatrics and Reproductive Medicine ; covid19
Subject code	610
Publishing date	2020-07-01
Publisher	eScholarship, University of California
Publishing country	us
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: As We Went to Press: COVID-19 Continues to SpreadAcute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19)

AJN The American Journal of Nursing

Abstract: Updates on the coronavirus BACKGROUND: Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients However, ... ...

Abstract	Updates on the coronavirus BACKGROUND: Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients However, management of pregnant patients who are critically ill with coronavirus disease 2019 (COVID-19) infection is complicated by physiologic changes and other pregnancy considerations and requires balancing maternal and fetal well-being CASE: We report the case of a patient at 28 weeks of gestation with acute respiratory distress syndrome (ARDS) from COVID-19 infection, whose deteriorating respiratory condition prompted delivery Our patient's oxygenation and respiratory mechanics improved within hours of delivery, though she required prolonged mechanical ventilation until postpartum day 10 Neonatal swabs for SARS-CoV-2 and COVID-19 immunoglobulin (Ig) G and IgM were negative CONCLUSION: We describe our multidisciplinary management of a preterm pregnant patient with ARDS from COVID-19 infection and her neonate Corresponding author: Stephanie L Gaw, MD, PhD, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA;email: Stephanie Gaw@ucsf edu Financial Disclosure Anne L Donovan disclosed that funding was provided to her institution from the Network for the Investigation of Delirium: Unifying Scientists (Pilot Grant Funding) Money was paid to her from the Agency for Healthcare Research and Quality (paid consultancy) Mary Prahl disclosed that in the article, the case involves a pregnant woman who received compassionate use remdesivir Her spouse is employed at the company that makes remdesivir Her role in this case was solely confined to the management of the neonate, and she had no involvement or influence in management of woman who received the compassionate use drug The other authors did not report any potential conflicts of interest Each author has confirmed compliance with the journal's requirements for authorship Peer reviews and author correspondence are available at http://links lww com/AOG/B897 Received April 16, 2020 Received in revised form April 23, 2020 Accepted April 29, 2020 © 2020 by The American College of Obstetricians and Gynecologists Published by Wolters Kluwer Health, Inc All rights reserved
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #594659
Database	COVID19

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