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  1. Article: Roadmap to the Effective Use of Continuous Glucose Monitoring in Primary Care.

    Martens, Thomas W

    Diabetes spectrum : a publication of the American Diabetes Association

    2023  Volume 36, Issue 4, Page(s) 306–314

    Abstract: Diabetes technology has undergone a remarkable evolution in the past decade, with dramatic improvements in accuracy and ease of use. Continuous glucose monitor (CGM) technology, in particular, has evolved, and coevolved with widely available consumer ... ...

    Abstract Diabetes technology has undergone a remarkable evolution in the past decade, with dramatic improvements in accuracy and ease of use. Continuous glucose monitor (CGM) technology, in particular, has evolved, and coevolved with widely available consumer smartphone technology, to provide a unique opportunity to both improve management and decrease the burden of management for populations across nearly the entire spectrum of people living with diabetes. Capitalizing on that opportunity, however, will require both adoption of and adaptations to the use of CGM technology in the broader world of primary care. This article focuses on mechanisms to expand pathways to optimized glycemic management, thereby creating a robust roadway capable of improving care across broad populations managed in primary care settings. Recent expansions in access to devices combined with improved mechanisms for data access at the time of primary care visits and improved training and evolving systems of support within primary care, hold potential to improve glycemic management in diabetes across the health care spectrum.
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2211544-4
    ISSN 1040-9165
    ISSN 1040-9165
    DOI 10.2337/dsi23-0001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The faiths of two doctors: Thomas Browne and William Osler.

    Martens, P

    Perspectives in biology and medicine

    1992  Volume 36, Issue 1, Page(s) 120–128

    MeSH term(s) Canada ; England ; History, 19th Century ; History, 20th Century ; Physicians/history ; Religion and Medicine ; Religion and Science
    Language English
    Publishing date 1992
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 80373-x
    ISSN 1529-8795 ; 0031-5982
    ISSN (online) 1529-8795
    ISSN 0031-5982
    DOI 10.1353/pbm.1993.0048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Urgent Cardiac Surgery and COVID-19 Infection: Uncharted Territory: Reply.

    Martens, Thomas

    The Annals of thoracic surgery

    2020  Volume 111, Issue 5, Page(s) 1735

    MeSH term(s) Aneurysm, Dissecting ; COVID-19 ; Cardiac Surgical Procedures/adverse effects ; Humans ; SARS-CoV-2 ; Thoracic Surgery
    Language English
    Publishing date 2020-10-09
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Continuous glucose monitoring in primary care - are we there?

    Martens, Thomas W

    Current opinion in endocrinology, diabetes, and obesity

    2021  Volume 29, Issue 1, Page(s) 10–16

    Abstract: Purpose of review: In this review, we examine the expanding role of continuous glucose monitoring in glycaemic management in primary care.: Recent findings: Improving technology and decreasing cost have increased the uptake of use of continuous ... ...

    Abstract Purpose of review: In this review, we examine the expanding role of continuous glucose monitoring in glycaemic management in primary care.
    Recent findings: Improving technology and decreasing cost have increased the uptake of use of continuous glucose monitoring (CGM) for glycaemic management in primary care, wherein most diabetes is managed. Optimized use of this technology, however, will require a convergence of several factors. Availability of devices for people with diabetes, availability of data at the time of clinical interactions, and expertise in interpretation of CGM and ambulatory glucose profile (AGP) data, as well as optimization of therapies, will be required. Significant progress has been made in all three areas in recent years, yet creating systems of support for widespread use of CGM in primary care remains an area of active investigation.
    Summary: There has been significant uptake in the use of CGM in the management of diabetes in primary care. Optimized use, however, requires both access to CGM data and the expertise to use the data. Although promising strategies have emerged, the task of generalizing these strategies to the broad population of primary care in America is ongoing. CGM technology holds significant potential for improving glycaemic management in primary care, yet important work remains to leverage the full potential of this promising technology.
    MeSH term(s) Blood Glucose ; Blood Glucose Self-Monitoring ; Diabetes Mellitus ; Diabetes Mellitus, Type 1 ; Glucose ; Humans ; Primary Health Care
    Chemical Substances Blood Glucose ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2021-11-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2272017-0
    ISSN 1752-2978 ; 1752-296X
    ISSN (online) 1752-2978
    ISSN 1752-296X
    DOI 10.1097/MED.0000000000000689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Simulation study on high spatio-temporal resolution acousto-electrophysiological neuroimaging.

    Schoeters, Ruben / Tarnaud, Thomas / Martens, Luc / Tanghe, Emmeric

    Journal of neural engineering

    2024  Volume 20, Issue 6

    Abstract: Objective. ...

    Abstract Objective.
    MeSH term(s) Animals ; Mice ; Humans ; Brain/physiology ; Electroencephalography/methods ; Neuroimaging ; Ultrasonics ; Head
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2170901-4
    ISSN 1741-2552 ; 1741-2560
    ISSN (online) 1741-2552
    ISSN 1741-2560
    DOI 10.1088/1741-2552/ad169c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Primary Care and Diabetes Technologies and Treatments.

    Martens, Thomas W / Simonson, Gregg D / Carlson, Anders L / Bergenstal, Richard M

    Diabetes technology & therapeutics

    2024  Volume 26, Issue S1, Page(s) S153–S171

    MeSH term(s) Humans ; Diabetes Mellitus/therapy ; Primary Health Care
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2024.2510
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: How use of continuous glucose monitoring can address therapeutic inertia in primary care.

    Martens, Thomas W / Parkin, Christopher G

    Postgraduate medicine

    2022  Volume 134, Issue 6, Page(s) 576–588

    Abstract: A significant proportion of individuals with diabetes have suboptimal glycemic management. Studies have shown that persistent hyperglycemia significantly increases the risks for both acute and long-term microvascular and macrovascular complications of ... ...

    Abstract A significant proportion of individuals with diabetes have suboptimal glycemic management. Studies have shown that persistent hyperglycemia significantly increases the risks for both acute and long-term microvascular and macrovascular complications of diabetes. A key contributor to suboptimal glycemic management is therapeutic inertia in which clinicians delay intensifying therapy when patients are not meeting their glycemic goals. During the past five years, an increasing number of individuals with type 1 diabetes (T1D) and insulin-treated type 2 diabetes (T2D) have adopted the use of continuous glucose monitoring (CGM) for daily measurement of glucose levels. As demonstrated in numerous clinical trials and real-world observational studies, use of CGM improves glycated hemoglobin (HbA1c) and reduces the occurrence and severity of hypoglycemia. However, for primary care clinicians who are unfamiliar with using CGM, integrating this technology into clinical practice can be daunting. In this article, we discuss the benefits and rationale for using CGM compared with traditional blood glucose monitoring (BGM), review the evidence supporting the clinical value of CGM in patients with T1D and T2D, and describe how use of CGM in primary care can facilitate appropriate and more timely therapy adjustments.
    MeSH term(s) Blood Glucose ; Blood Glucose Self-Monitoring ; Diabetes Mellitus, Type 1/chemically induced ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 2 ; Glycated Hemoglobin A/analysis ; Humans ; Hypoglycemic Agents ; Insulin/therapeutic use ; Primary Health Care
    Chemical Substances Blood Glucose ; Glycated Hemoglobin A ; Hypoglycemic Agents ; Insulin
    Language English
    Publishing date 2022-05-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 410138-8
    ISSN 1941-9260 ; 0032-5481
    ISSN (online) 1941-9260
    ISSN 0032-5481
    DOI 10.1080/00325481.2022.2080419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Urgent Cardiac Surgery and COVID-19 infection

    Martens, Thomas

    The Annals of Thoracic Surgery ; ISSN 0003-4975

    Uncharted Territory

    2020  

    Keywords Surgery ; Pulmonary and Respiratory Medicine ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.athoracsur.2020.09.007
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Sex, lies, and iron deficiency: a call to change ferritin reference ranges.

    Martens, Kylee / DeLoughery, Thomas G

    Hematology. American Society of Hematology. Education Program

    2023  Volume 2023, Issue 1, Page(s) 617–621

    Abstract: Iron deficiency is a very common and treatable disorder. Of all the tests available to diagnose iron deficiency, the serum ferritin is the most able to discriminate iron deficiency from other disorders. However, the reference range for ferritin in many ... ...

    Abstract Iron deficiency is a very common and treatable disorder. Of all the tests available to diagnose iron deficiency, the serum ferritin is the most able to discriminate iron deficiency from other disorders. However, the reference range for ferritin in many laboratories will lead to underdiagnosis of iron deficiency in women. Studies have shown that 30%-50% of healthy women will have no marrow iron stores, so basing ferritin cutoffs on the lowest 2.5% of sampled ferritins is not appropriate. In addition, several lines of evidence suggest the body physiologic ferritin "cutoff" is 50  ng/mL. Work is needed to establish more realistic ferritin ranges to avoid underdiagnosing a readily treatable disorder.
    MeSH term(s) Humans ; Female ; Ferritins ; Iron/metabolism ; Reference Values ; Iron Deficiencies ; Bone Marrow/metabolism ; Anemia, Iron-Deficiency/diagnosis ; Anemia, Iron-Deficiency/therapy
    Chemical Substances Ferritins (9007-73-2) ; Iron (E1UOL152H7)
    Language English
    Publishing date 2023-12-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2084287-9
    ISSN 1520-4383 ; 1520-4391
    ISSN (online) 1520-4383
    ISSN 1520-4391
    DOI 10.1182/hematology.2023000494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The membrane surface as a platform that organizes cellular and biochemical processes.

    Leonard, Thomas A / Loose, Martin / Martens, Sascha

    Developmental cell

    2023  Volume 58, Issue 15, Page(s) 1315–1332

    Abstract: Membranes are essential for life. They act as semi-permeable boundaries that define cells and organelles. In addition, their surfaces actively participate in biochemical reaction networks, where they confine proteins, align reaction partners, and ... ...

    Abstract Membranes are essential for life. They act as semi-permeable boundaries that define cells and organelles. In addition, their surfaces actively participate in biochemical reaction networks, where they confine proteins, align reaction partners, and directly control enzymatic activities. Membrane-localized reactions shape cellular membranes, define the identity of organelles, compartmentalize biochemical processes, and can even be the source of signaling gradients that originate at the plasma membrane and reach into the cytoplasm and nucleus. The membrane surface is, therefore, an essential platform upon which myriad cellular processes are scaffolded. In this review, we summarize our current understanding of the biophysics and biochemistry of membrane-localized reactions with particular focus on insights derived from reconstituted and cellular systems. We discuss how the interplay of cellular factors results in their self-organization, condensation, assembly, and activity, and the emergent properties derived from them.
    MeSH term(s) Cell Membrane/metabolism ; Membranes ; Signal Transduction ; Cell Nucleus
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2054967-2
    ISSN 1878-1551 ; 1534-5807
    ISSN (online) 1878-1551
    ISSN 1534-5807
    DOI 10.1016/j.devcel.2023.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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