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Article ; Online: Evaluation of Clinical, Hormonal and Ultrasound Parameters of Male Reproductive System in Leprosy: A Cross-Sectional Study.

Hegde, Manasa / Kanathur, Shilpa / Shanmukhappa, Asha G / Srinivas, M R

2024 Volume 68, Issue 6, Page(s) 723

Abstract: Background and objectives: Testicular involvement in leprosy is neglected as it is insidious and silent, although it can have an impact on quality of life. Our study aimed at evaluating and estimating the frequency of the hormonal, radiological and ... ...

Abstract	Background and objectives: Testicular involvement in leprosy is neglected as it is insidious and silent, although it can have an impact on quality of life. Our study aimed at evaluating and estimating the frequency of the hormonal, radiological and clinical parameters in these patients. Materials and methods: A cross-sectional study was conducted including 31 male leprosy patients attending our OPD. After detailed clinical assessment, patients were subjected to ultrasonological with Doppler examination of the scrotum and hormonal evaluation by ELISA technique for serum follicle-stimulating hormone (FSH), luteinising hormone (LH) and total testosterone. Results: Thirty-one patients were included with ages ranging from 19 to 54 with a mean of 34 years. Decreased libido (19.3%) was significantly observed in the abnormal FSH ( Conclusion: A sizeable proportion (74%) of the study sample had testicular atrophy. The significant association between increased RI and testicular atrophy, especially in patients with infertility, emphasises the ancillary role of Doppler indices in methodical diagnosis. Risk factors noted in the study include increased bacillary index, delayed initiation of treatment and recurrent ENL. Early detection, early initiation of MDT and specific therapies such as testosterone replacement can help improve the quality of life.
Language	English
Publishing date	2024-01-09
Publishing country	India
Document type	Journal Article
ZDB-ID	416069-1
ISSN	1998-3611 ; 0019-5154
ISSN (online)	1998-3611
ISSN	0019-5154
DOI	10.4103/ijd.ijd_539_23
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Article ; Online: The influence of digital technologies on resilient performance: Contributions, drawbacks, and a research agenda.

Saurin, Tarcisio Abreu / Patriarca, Riccardo / Hegde, Sudeep / Rayo, Mike

Applied ergonomics

2024 Volume 118, Page(s) 104290

Abstract: The growing use of digital technologies (DTs) has a myriad of implications to socio-technical systems, which are not yet fully recognised. This paper investigates the contributions and drawbacks of DTs to resilient performance (RP), an aspect that so far ...

Abstract	The growing use of digital technologies (DTs) has a myriad of implications to socio-technical systems, which are not yet fully recognised. This paper investigates the contributions and drawbacks of DTs to resilient performance (RP), an aspect that so far has received less attention in comparison to others such as efficiency. To this end, a survey questionnaire was applied to 79 academics and practitioners linked to resilience engineering. Data analysis involved descriptive statistics and a thematic analysis of the open-text responses to the survey. Mixed impacts were identified, with 10 themes related to contributions and 16 to drawbacks. Regarding the contributions, the results highlighted the use of DTs for monitoring and anticipating system performance. Machine learning seems to be the most promising approach for this purpose. A key drawback is the need for developing new skills across the workforce so that they can make sense of the outputs of DTs and are aware of their strengths and weaknesses. The human role is expected to remain crucial for RP, which makes the current coordination difficulties with DTs even more important to address. A research agenda composed of five topics is proposed, encompassing description, prescription, and assessment. The agenda emphasizes the need for mapping the attributes or functionalities of DTs onto resilience concepts, models, and frameworks.
Language	English
Publishing date	2024-04-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2003513-5
ISSN	1872-9126 ; 0003-6870
ISSN (online)	1872-9126
ISSN	0003-6870
DOI	10.1016/j.apergo.2024.104290
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Article: Variation in Exon 29 of the NOS1 Gene Does Not Contribute to Parkinson's Disease in the North Karnataka Population.

Bulagouda, Rudragouda / Hegde, Smita / Hegde, Rajat / Hiremath, Ashwini / Wali, G M / Kadakol, Gurushantappa S

Cureus

2023 Volume 15, Issue 9, Page(s) e45347

Abstract: Introduction: Nitric oxide (NO) overproduction has been found to have neurotoxic effects on the brain. Moreover, in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced, the suppression of the NO-synthesizing enzymes, such as neuronal nitric ... ...

Abstract	Introduction: Nitric oxide (NO) overproduction has been found to have neurotoxic effects on the brain. Moreover, in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced, the suppression of the NO-synthesizing enzymes, such as neuronal nitric oxide synthase (nNOS) and inducible NOS (iNOS), has neuroprotective benefits in Parkinson's disease (PD). These findings imply that NOS may have a role in regulating the nigral dopaminergic neurons' tolerance to environmental stressors in PD. Objective: In the present study, we investigated variations in the Methods: PD patients who visited the neurology departments of several medical colleges and hospitals in North Karnataka, India, between 2009 and 2011 were included in the study. The detailed clinic pathological details were obtained from 100 PD patients. Genomic DNA was isolated using the kit method followed by the evaluation of the quality and quantity of isolated gDNA. Polymerase chain reaction (PCR) amplification of exon 29 was performed, and sequencing was performed using the Applied Biosystems Results: The present study is comprised of 100 PD patients, which includes 65 males and 35 females. There were 64 sporadic, 34 idiopathic, and two familial PD cases. The majority (67.1%) of PD cases were from metropolitan areas. Community-based segregation showed that the maximum cases were from Hindu Lingayat. A proportion (90.8%) of the patients had tremors, 32.7% of them displayed slowness in their daily tasks, and 8.1% of them had dyskinesia. Molecular analysis showed two untranslated region (UTR) variations g.151787 del T (rs1434015950) and g.151745 C>T (rs2682826) in our study group. Conclusion: The absence of mutations in the targeted
Language	English
Publishing date	2023-09-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.45347
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Article ; Online: DEEP LEARNING ALGORITHMS SHOW SOME POTENTIAL AS AN ADJUNCTIVE TOOL IN CARIES DIAGNOSIS.

Hegde, Shwetha / Gao, Jinlong

The journal of evidence-based dental practice

2022 Volume 22, Issue 4, Page(s) 101772

Abstract: ... M, Krois J, Uribe SE, Mahmoudinia E, Rokhshad R, Nadimi M, Schwendicke F, Deep learning for caries ...

Abstract	Article title and bibliographic information: Mohammad-Rahimi H, Reza Motamedian S, Hossein Rohban M, Krois J, Uribe SE, Mahmoudinia E, Rokhshad R, Nadimi M, Schwendicke F, Deep learning for caries detection: A systematic review, J Dent, 2022,122, 104115. ISSN 0300-5712 https://doi.org/10.1016/j.jdent.2022.104115. Source of funding: Information not available TYPE OF STUDY/DESIGN: Systematic review.
Language	English
Publishing date	2022-08-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2056058-8
ISSN	1532-3390 ; 1532-3382
ISSN (online)	1532-3390
ISSN	1532-3382
DOI	10.1016/j.jebdp.2022.101772
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Article ; Online: Influence of wearing complete denture on the glycemic control, serum lipid, and proteins in patients with diabetes.

Gupte, Rishabh / Shetty, Manoj / Hegde, Chethan

Journal of Indian Prosthodontic Society

2023 Volume 23, Issue 3, Page(s) 259–265

Abstract: Aims: The aim of this study was to assess the impact of prosthodontic rehabilitation on glycemic and lipid control in functionally and completely edentulous patients with diabetes.: Setting and design: An in vivo study conducted with the intention of ...

Abstract	Aims: The aim of this study was to assess the impact of prosthodontic rehabilitation on glycemic and lipid control in functionally and completely edentulous patients with diabetes. Setting and design: An in vivo study conducted with the intention of studying the potential link between edentulism and impaired masticatory efficiency with the nutritional status in diabetic patients. Materials and methods: A total of 20 diabetic patients based on the inclusion criteria were selected. They were rehabilitated using a removable prosthesis, and observations were made across three parameters - glycosylated hemoglobin (HbA1C), serum cholesterol (S col), and serum protein (SP) at three stages - baseline, 3 months, and 6 months posttreatment. This was done to gauge the impact of the prosthetic rehabilitation on their health due to an increased masticatory efficiency potentially causing changes in dietary patterns. Statistical analysis used: •Inter group comparison (>2 groups) was done using one way ANOVA followed by pair wise comparison using post hoc test. •Intra group comparison was done using repeated measures ANOVA (for>2 observations) followed by post Hoc test. For all the statistical tests, P < 0.05 was considered to be statistically significant, keeping α error at 5% and β error ati20%, thus giving a power to the study as 80%. Results: Hba1c at the baseline had a mean value of 8.04%, which reduced to 7.87% at the 3-month stage and 7.38% at the 6-month stage. S col at the baseline had a mean of 151.6 mg/dL; at the 3-month follow-up, it was 166.5 mg/dL, and at the 6-month follow-up, it was 173.95 mg/dL. SP had a mean baseline value of 6.38 mg/dL, which progressed to 6.67 mg/dL at the 3-month stage and 6.97 at the 6-month stage. Conclusion: Within the limitations of this study, it can be concluded that after 6 months of prosthetic rehabilitation in edentulous/functionally edentulous patients: There was a reduction in HbA1c (8.04%-7.38%); however, it was found to be statistically insignificant at that stage There was an increase in S col (151.6 mg/dL-173.95 mg/dL); it was found to be statistically significant There was an increase in SP (6.38 mg/dL-6.97 mg/dL); however, it was found to be statistically insignificant at that stage.
MeSH term(s)	Humans ; Glycemic Control ; Glycated Hemoglobin ; Denture, Complete ; Mouth, Edentulous/rehabilitation ; Diabetes Mellitus ; Lipids
Chemical Substances	Glycated Hemoglobin ; Lipids
Language	English
Publishing date	2023-11-01
Publishing country	India
Document type	Journal Article
ISSN	1998-4057
ISSN (online)	1998-4057
DOI	10.4103/jips.jips_284_23
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Article: An Unusual Case of Spontaneous Fracture and Vesical Transmigration of Intrauterine Contraceptive Device.

Shah, Krupa / Bhat, Rajeshwari / Shivaramaiya, Manasa / Hegde, Padmaraj

Journal of obstetrics and gynaecology of India

2023 Volume 73, Issue 6, Page(s) 544–546

Language	English
Publishing date	2023-06-07
Publishing country	India
Document type	Case Reports
ZDB-ID	410688-x
ISSN	0971-9202 ; 0022-3190
ISSN	0971-9202 ; 0022-3190
DOI	10.1007/s13224-023-01763-x
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Article ; Online: Persistent umbilicated papules on the left ear and neck in an adolescent boy.

Hegde, Shibhani Sudheer / Srinivas, Sahana M / Tirumalae, Rajalakshmi

Pediatric dermatology

2023 Volume 40, Issue 3, Page(s) 562–564

MeSH term(s)	Male ; Humans ; Adolescent ; Neck ; Skin Abnormalities/pathology ; Face ; Hyperplasia/pathology ; Sebaceous Glands/pathology
Language	English
Publishing date	2023-05-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	605539-4
ISSN	1525-1470 ; 0736-8046
ISSN (online)	1525-1470
ISSN	0736-8046
DOI	10.1111/pde.15221
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Article: Effects of incorporation of nano particles on the mechanical properties of maxillofacial silicone elastomer subjected to outdoor weathering.

Anjali, Anjali / Chethan, Hegde

Heliyon

2024 Volume 10, Issue 3, Page(s) e25039

Abstract: ... weathering by R.N Akash et al. in the year 2015 [(Akash and Guttal, 2015). The samples were divided ... The tear strength of silicone specimens with 1.5 % zirconium silicate it was found to be 5.37 kN/m ...

Abstract	Statement of problem: Natural weathering has varied effects on the service life of maxillofacial silicones due to its direct implications on the tear strength and hardness of the material. Purpose: The purpose of this study was to evaluate the effect of incorporation of nano oxides on the mechanical properties of maxillofacial silicone elastomer subjected to outdoor weathering. Material and methods: This in-vitro study was conducted in the Department of Prosthodontics, on maxillofacial silicone elastomer samples incorporated with nano particles subjected to outdoor weathering for a time period of 6 months. Sample size of eighty-four was determined using the results of the article studying the effects of incorporation of nano oxides on the colour stability of maxillofacial silicone elastomer subjected to outdoor weathering by R.N Akash et al. in the year 2015 [(Akash and Guttal, 2015). The samples were divided into three groups. Control group comprised of 14, maxillofacial silicone elastomer without nano particles, the second group, ZnO Results: The hardness values for maxillofacial silicone in group 3 (with zirconium silicate) was found to be 38.74 which was the lowest in comparison to control and zinc oxide groups. The tear strength of silicone specimens with 1.5 % zirconium silicate it was found to be 5.37 kN/m, which was the highest in comparison to the zinc oxide and the control groups. Conclusions: The difference in mean hardness and mean tear strength of silicone elastomer with 1.5 % zirconium silicate was found to be, statistically significant. This study suggests that, even after being exposed to the effects of natural weathering, zirconium silicate nano particles may keep the tear strength and hardness of medical grade maxillofacial silicone elastomer up to acceptable ISO criteria.
Language	English
Publishing date	2024-01-21
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e25039
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Article ; Online: Migration of Iophendylate Myelography Contrast to the Brain With Successful Thrombectomy.

Tu, Long / Hegde, Rahul G / Prust, Morgan / Mageid, Razaz / Hebert, Ryan / Jasne, Adam S

Neurology

2024 Volume 102, Issue 8, Page(s) e209314

MeSH term(s)	Humans ; Iophendylate ; Myelography ; Contrast Media ; Brain/diagnostic imaging ; Head
Chemical Substances	Iophendylate (99-79-6) ; Contrast Media
Language	English
Publishing date	2024-03-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	207147-2
ISSN	1526-632X ; 0028-3878
ISSN (online)	1526-632X
ISSN	0028-3878
DOI	10.1212/WNL.0000000000209314
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Article ; Online: Imaging in international sporting event: experience from the Birmingham Commonwealth Games 2022.

Pillai, J K / Chari, B / Hegde, G / Chapman, P / Halls, M / Botchu, R

Clinical radiology

2023 Volume 78, Issue 6, Page(s) e477–e485

Abstract: Aim: To explain the design and delivery of diagnostic imaging and image-guided intervention services for an international games. The authors share their experiences from the Birmingham Commonwealth Games 2022.: Materials and methods: A retrospective ... ...

Abstract	Aim: To explain the design and delivery of diagnostic imaging and image-guided intervention services for an international games. The authors share their experiences from the Birmingham Commonwealth Games 2022. Materials and methods: A retrospective analysis was undertaken of anonymised data from the Zillion, Easyvision (RIS and PACS), and Encounter platforms for image viewing, interpretation and reporting during the Games. The data collected included age and gender, type of sport, nature of the injury, and imaging findings with diagnoses. Results: The number of individuals who had radiological investigations at the Birmingham Commonwealth Games was 518 and the vast majority of them were athletes (90 %). The average age of athletes who had imaging was 28 years and that of non-athletes who accessed imaging services was 46.4 years with male predominance. Magnetic resonance imaging was the most frequently used imaging technique and the lower limb was the most frequently imaged body part. Athletes playing netball and beach volleyball had the highest percentage of injuries. Conclusion: The authors share their experience from the Birmingham Commonwealth Games 2022 regarding the nuances and challenges in radiology service provision for an international sports event that would be helpful for musculoskeletal radiologists in the design and delivery of similar international events in the future.
MeSH term(s)	Male ; Humans ; Adult ; Female ; Athletic Injuries ; Retrospective Studies ; Sports ; Athletes ; Magnetic Resonance Imaging
Language	English
Publishing date	2023-03-10
Publishing country	England
Document type	Journal Article
ZDB-ID	391227-9
ISSN	1365-229X ; 0009-9260
ISSN (online)	1365-229X
ISSN	0009-9260
DOI	10.1016/j.crad.2023.02.014
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