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  1. Article ; Online: Left ventricular aneurysm complicating apical hypertrophic cardiomyopathy.

    Toner, Liam / Koshy, Anoop / Farouque, Omar / Cotroneo, John

    BMJ case reports

    2020  Volume 13, Issue 10

    MeSH term(s) Adult ; Cardiomyopathy, Hypertrophic/complications ; Heart Aneurysm/etiology ; Heart Ventricles/pathology ; Humans ; Male
    Language English
    Publishing date 2020-10-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-238861
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  2. Article ; Online: Osteosarcoma (osteogenic sarcoma) of the jaws presenting in general dental practice - a series of four cases.

    Costello, Liam / Toner, Mary / Pierse, Dermot / Stassen, Leo F A

    British dental journal

    2021  Volume 230, Issue 9, Page(s) 583–586

    Abstract: Introduction Osteosarcoma is the most common primary malignant bone tumour, usually arising in the long bones, with occurrence in the head and neck accounting for 8% of all osteosarcomas. Clinical features include swelling, pain, facial dysesthesia and ... ...

    Abstract Introduction Osteosarcoma is the most common primary malignant bone tumour, usually arising in the long bones, with occurrence in the head and neck accounting for 8% of all osteosarcomas. Clinical features include swelling, pain, facial dysesthesia and abnormal mobility of teeth. Treatment consists of a combination of surgery, radiotherapy and chemotherapy.Case series Here, we present four cases of osteosarcoma of the jaws - two maxillary and two mandibular. All cases were initially assessed in the dental primary care setting before being referred for specialist opinion.Discussion The purpose of this paper is to present an overview of an uncommon but serious disease which can mimic common life-threatening dento-facial conditions. We discuss the diagnostic features, with an overview of clinical, histopathological and radiographic features.Conclusion These cases are important reminders of the potential clinical and radiographic appearance of a rare cause of facial swelling, and highlight the role of the general dental practitioner in early diagnosis and referral.
    MeSH term(s) Bone Neoplasms ; Dentists ; Humans ; Maxilla ; Osteosarcoma ; Professional Role
    Language English
    Publishing date 2021-05-14
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 218090-x
    ISSN 1476-5373 ; 0007-0610
    ISSN (online) 1476-5373
    ISSN 0007-0610
    DOI 10.1038/s41415-021-2943-x
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    Ul III Zs.143: Show issues Location:
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  3. Article: Late recurrence of atrial fibrillation and flutter in patients referred for elective electrical cardioversion.

    Toner, Liam / Proimos, Helena / Scully, Timothy / Ko, Jefferson / Koshy, Anoop / Horrigan, Mark / Lim, Han S / Lin, Tina / Farouque, Omar

    Kardiologiia

    2023  Volume 63, Issue 1, Page(s) 54–59

    Abstract: Aim    The primary aim was to ascertain long-term rates of atrial fibrillation (AF) recurrence in this all-comer patient population undergoing elective electrical cardioversion (DCR). Secondary aims included procedural DCR success, clinical predictors of ...

    Abstract Aim    The primary aim was to ascertain long-term rates of atrial fibrillation (AF) recurrence in this all-comer patient population undergoing elective electrical cardioversion (DCR). Secondary aims included procedural DCR success, clinical predictors of long-term maintenance of sinus rhythm (SR) and AF related hospitalizations.Material and Methods    A retrospective cohort study was conducted. Consecutive patients (n=316) undergoing elective DCR were included.Results    Successful immediate reversion to SR was attained in 266 (84 %) of patients. 224 (84 %) patients were followed up for a median period of 3.5 years (IQR 2.7-4.3). Most patients (150 [67 %]) had recurrence of AF / flutter at a median time of 240 days. Clinical predictors of AF recurrence included a history of AF (HR 0.63, p=0.038) and a dilated left atrium (HR 4.13, p=0.048). Maintenance of SR was associated with fewer unplanned hospitalizations for AF (HR 3.25, p<0.01).Conclusion    There was high procedural success post DCR. However, long-term rates of AF recurrence were high, and AF recurrences were associated with increased hospitalizations. These findings underscore the importance of clinical vigilance and multi-modal management as part of a comprehensive and effective rhythm control strategy.
    MeSH term(s) Humans ; Atrial Fibrillation ; Electric Countershock/methods ; Retrospective Studies ; Heart Atria ; Atrial Flutter ; Recurrence ; Treatment Outcome
    Language English
    Publishing date 2023-01-31
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 131029-x
    ISSN 0022-9040
    ISSN 0022-9040
    DOI 10.18087/cardio.2023.1.n2145
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  4. Article ; Online: Spontaneous reversion of paroxysmal atrial fibrillation detected by smart watch.

    Toner, Liam / Al-Kaisey, Ahmed M / Koshy, Anoop / Lim, Han Sung

    BMJ case reports

    2020  Volume 13, Issue 2

    MeSH term(s) Aged, 80 and over ; Atrial Fibrillation/diagnosis ; Electrocardiography, Ambulatory/instrumentation ; Female ; Heart Rate ; Humans ; Monitoring, Ambulatory/instrumentation ; Remission, Spontaneous ; Tachycardia, Paroxysmal/diagnosis ; Wearable Electronic Devices
    Language English
    Publishing date 2020-02-04
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-233431
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  5. Article ; Online: Takotsubo Cardiomyopathy Complicated by Cardiogenic Shock Secondary to Left Ventricular Outflow Tract Obstruction and Severe Mitral Regurgitation.

    Toner, Liam / Rodrigues, Thalys Sampaio / Undrill, Simon / Ajani, Andrew E / Yeoh, Julian / Clark, David

    Cardiovascular revascularization medicine : including molecular interventions

    2021  Volume 28S, Page(s) 236–238

    MeSH term(s) Humans ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/etiology ; Mitral Valve Insufficiency/surgery ; Shock, Cardiogenic/diagnosis ; Shock, Cardiogenic/etiology ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/diagnostic imaging ; Ventricular Outflow Obstruction/diagnostic imaging ; Ventricular Outflow Obstruction/etiology
    Language English
    Publishing date 2021-03-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2212113-4
    ISSN 1878-0938 ; 1553-8389
    ISSN (online) 1878-0938
    ISSN 1553-8389
    DOI 10.1016/j.carrev.2021.03.009
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    Zs.A 5562: Show issues Location:
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  6. Article ; Online: Clinical Characteristics and Trends in Heart Failure Hospitalizations: An Australian Experience During the COVID-19 Lockdown.

    Toner, Liam / Koshy, Anoop N / Ko, Jefferson / Driscoll, Andrea / Farouque, Omar

    JACC. Heart failure

    2020  Volume 8, Issue 10, Page(s) 872–875

    MeSH term(s) Australia ; Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Heart Failure/epidemiology ; Hospitalization ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-11
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2020.05.014
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  7. Article ; Online: Biventricular Function is Impaired in Right Ventricular Septal Pacing-A Prospective Study Using Myocardial Strain Imaging.

    Toner, Liam / Chen, Janet X C / Ramchand, Jay / Srivastava, Piyush / O'Donnell, David / Calafiore, Paul / Jones, Elizabeth

    Heart, lung & circulation

    2022  Volume 32, Issue 3, Page(s) 373–378

    Abstract: Background: Left ventricular (LV) dysfunction is known to occur after right ventricular (RV) pacing; the effect on RV function is less well studied. The aim of this study was to assess the impact of RV mid-septal pacing upon RV function using the novel ... ...

    Abstract Background: Left ventricular (LV) dysfunction is known to occur after right ventricular (RV) pacing; the effect on RV function is less well studied. The aim of this study was to assess the impact of RV mid-septal pacing upon RV function using the novel parameters of speckle-tracking derived RV global longitudinal strain (RV GLS) and RV free wall strain (RV FWS), as well as the conventional parameters RV fractional area change (FAC), tricuspid annular plane systolic excursion (TAPSE), and tricuspid annular systolic velocity (RV S').
    Methods: Thirty-two (32) consecutive patients with normal baseline LV and RV function requiring permanent pacemaker insertion (for high-grade AV block or sinus node dysfunction) were prospectively recruited. Echocardiography was performed prior to implantation, at 1 day, 1 month and 1 year after implantation, with 29 patients completing follow-up.
    Results: After 1 year, three patients (10%) with otherwise normal RV parameters developed abnormal RV strain patterns. Compared to 1 day after implantation, at 1 year significant reductions were observed in mean RV GLS (-24.8 to -21.8%) RV S' (15.1 to 12.2 cm/s), TAPSE (24.2 to 21.9 mm), RV GLS (-24.8 to -21.8%), left ventricular ejection fraction (LVEF) (66.0 to 57.9%), LV GLS (-19.9 to 17.0), all p<0.01. There was a non-significant reduction for RV FWS (-29.0 to -26.7%, p=0.06) and there was no change in RV FAC (49.1 to 46.9%, p=0.24).
    Conclusion: We report abnormalities of RV strain developing 1 year after pacemaker insertion. Measurement of myocardial strain is emerging as an additional method to detect patients at risk of RV dysfunction in those who have undergone pacemaker implantation.
    MeSH term(s) Humans ; Prospective Studies ; Stroke Volume ; Ventricular Function, Left ; Echocardiography/methods ; Heart Ventricles/diagnostic imaging ; Ventricular Function, Right ; Ventricular Dysfunction, Right/diagnostic imaging ; Ventricular Dysfunction, Right/etiology
    Language English
    Publishing date 2022-12-20
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2022.11.004
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4988: Show issues Location:
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  8. Article ; Online: Acute coronary syndromes undergoing percutaneous coronary intervention in the COVID-19 era: comparable case volumes but delayed symptom onset to hospital presentation.

    Toner, Liam / Koshy, Anoop N / Hamilton, Garry W / Clark, David / Farouque, Omar / Yudi, Matias B

    European heart journal. Quality of care & clinical outcomes

    2020  Volume 6, Issue 3, Page(s) 225–226

    MeSH term(s) Acute Coronary Syndrome/surgery ; Aged ; Australia/epidemiology ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Emergency Service, Hospital/statistics & numerical data ; Facilities and Services Utilization ; Female ; Humans ; Male ; Middle Aged ; Pandemics ; Percutaneous Coronary Intervention/statistics & numerical data ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Time-to-Treatment
    Keywords covid19
    Language English
    Publishing date 2020-05-07
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2823451-0
    ISSN 2058-1742 ; 2058-5225
    ISSN (online) 2058-1742
    ISSN 2058-5225
    DOI 10.1093/ehjqcco/qcaa038
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  9. Article ; Online: Epicardial CRT-D in a Pacing Dependant Patient Without Transvenous Options.

    Sugumar, Hariharan / Matalanis, George / Toner, Liam / O'Donnell, David

    Heart, lung & circulation

    2017  Volume 26, Issue 8, Page(s) e48–e49

    Abstract: Implantable cardioverter-defibrillator (ICD) and cardiac resynchronisation therapy (CRT) is generally limited to transvenous techniques especially in pacing-dependant patients. We describe a novel case in which an epicardial CRT-D system was successfully ...

    Abstract Implantable cardioverter-defibrillator (ICD) and cardiac resynchronisation therapy (CRT) is generally limited to transvenous techniques especially in pacing-dependant patients. We describe a novel case in which an epicardial CRT-D system was successfully implanted with a two-year follow-up in a pacing-dependant patient.
    Language English
    Publishing date 2017-08
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2016.12.013
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    Zs.A 4988: Show issues Location:
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  10. Article ; Online: Safety and Long-Term Clinical Outcomes of Fractional Flow Reserve Guided Coronary Revascularisation.

    Scully, Timothy G / Toner, Liam / Yeoh, Julian / Farouque, Omar / Yudi, Matias B / Horrigan, Mark / Clark, David J

    Heart, lung & circulation

    2021  Volume 30, Issue 9, Page(s) 1343–1347

    Abstract: Background: Increasingly, fractional flow reserve (FFR) is employed to assess coronary artery stenoses although there is limited real world long-term outcome data with a recent report questioning its safety. This study aimed to assess the in-hospital ... ...

    Abstract Background: Increasingly, fractional flow reserve (FFR) is employed to assess coronary artery stenoses although there is limited real world long-term outcome data with a recent report questioning its safety. This study aimed to assess the in-hospital complications and clinical outcomes up to 10 years after FFR-guided revascularisation at a tertiary Australian hospital.
    Methods: The cohort comprised 274 consecutive patients undergoing FFR from 2010 to 2015 with follow-up to 2020. In-hospital complications and long-term outcomes were compared between patients with FFR≤0.80 and FFR>0.80. Major adverse cardiac events (MACE) comprised cardiac death, myocardial infarction (MI) and target vessel revascularisation (TVR).
    Results: The FFR was ≤0.80 in 166 and >0.80 in 108 patients. Stable coronary disease was present in 95%. Revascularisation was undertaken in 86.7% of the FFR≤0.80 group and in 2.8% of the group with an FFR>0.80. In-hospital adverse events were 3.3% with no pressure wire-related coronary dissection, stroke or death. At median follow-up of 5 years, patients with FFR≤0.80 and FFR>0.80 had a similar rate of cardiac death (2.6% versus 5.0%, p=0.335) and MI (2.6% versus 6.9%, p=0.154). In the FFR>0.80 group, MACE (17.8% v 7.9%; p=0.018) and TVR (12.9% v 5.3%; p=0.033) were significantly higher.
    Conclusion: This observational study highlights the safety and long-term effectiveness of FFR-guided coronary revascularisation in patients with predominantly stable disease.
    MeSH term(s) Australia ; Coronary Angiography ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/surgery ; Coronary Stenosis/diagnosis ; Coronary Stenosis/surgery ; Fractional Flow Reserve, Myocardial ; Humans ; Percutaneous Coronary Intervention ; Treatment Outcome
    Language English
    Publishing date 2021-03-26
    Publishing country Australia
    Document type Journal Article ; Observational Study
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2021.02.009
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