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Article ; Online: Getting to the Right Place at the Right Time: Another Piece of the STEMI Puzzle.

Fiorilli, Paul N / Kolansky, Daniel M

Circulation. Cardiovascular interventions

2018 Volume 11, Issue 5, Page(s) e006700

MeSH term(s)	American Heart Association ; Humans ; Myocardial Infarction ; Percutaneous Coronary Intervention ; ST Elevation Myocardial Infarction
Language	English
Publishing date	2018-04-30
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	2450797-0
ISSN	1941-7632 ; 1941-7640
ISSN (online)	1941-7632
ISSN	1941-7640
DOI	10.1161/CIRCINTERVENTIONS.118.006700
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Article ; Online: Interventional cardiologists' attitudes towards pharmacogenetic testing and impact on antiplatelet prescribing decisions.

Hoffecker, Glenda / Kanter, Genevieve P / Xu, Yao / Matthai, William / Kolansky, Daniel M / Giri, Jay / Tuteja, Sony

Personalized medicine

2021 Volume 19, Issue 1, Page(s) 41–49

Abstract: Aim: ...

Abstract	Aim:
MeSH term(s)	Attitude ; Cardiologists ; Genotype ; Humans ; Pharmacogenetics ; Pharmacogenomic Testing
Language	English
Publishing date	2021-12-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2299146-3
ISSN	1744-828X ; 1741-0541
ISSN (online)	1744-828X
ISSN	1741-0541
DOI	10.2217/pme-2021-0088
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Zs.A 6549: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Acute coronary syndromes: morbidity, mortality, and pharmacoeconomic burden.

Kolansky, Daniel M

The American journal of managed care

2009 Volume 15, Issue 2 Suppl, Page(s) S36–41

Abstract: Acute coronary syndromes (ACS), which include unstable angina and myocardial infarction (MI) with or without ST-segment elevation, are life-threatening disorders that remain a source of high morbidity and mortality despite advances in treatment. Nearly 1. ...

Abstract	Acute coronary syndromes (ACS), which include unstable angina and myocardial infarction (MI) with or without ST-segment elevation, are life-threatening disorders that remain a source of high morbidity and mortality despite advances in treatment. Nearly 1.5 million hospital discharges involve patients with ACS. According to statistics from the American Heart Association (AHA), approximately 18% of men and 23% of women over the age of 40 will die within 1 year of having an initial recognized MI. The economic burden of ACS is also very high, costing Americans more than $150 billion, according to AHA estimates. Approximately 20% of the ACS patients are rehospitalized within 1 year, and nearly 60% of the costs related to ACS result from rehospitalization. However, the evidence-based therapeutic management of ACS remains suboptimal. An understanding of the drivers of morbidity, mortality, and costs associated with ACS will help in developing strategies to reduce the burden of the disease. The evidence regarding the effects of early revascularization and stenting on survival rates in ACS patients is discussed. Currently available evidence-based and new practice guidelines determine the pros and cons of invasive versus conservative strategies for treating ACS. By evaluating the predictors of optimal medical therapy and mortality post-discharge, healthcare providers involved in the managed care play a key role in providing efficient, safe, and cost-effective ACS treatment.
MeSH term(s)	Acute Coronary Syndrome/economics ; Acute Coronary Syndrome/epidemiology ; Acute Coronary Syndrome/therapy ; Cost of Illness ; Female ; Health Care Costs ; Humans ; Male ; Managed Care Programs ; Morbidity ; Risk Factors ; Survival Analysis ; United States
Language	English
Publishing date	2009-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2035781-3
ISSN	1936-2692 ; 1088-0224 ; 1096-1860
ISSN (online)	1936-2692
ISSN	1088-0224 ; 1096-1860
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Zs.A 5353: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Referral Rates for Cardiac Rehabilitation Among Eligible Inpatients After Implementation of a Default Opt-Out Decision Pathway in the Electronic Medical Record.

Adusumalli, Srinath / Jolly, Elizabeth / Chokshi, Neel P / Gitelman, Yevginiy / Rareshide, Charles A L / Kolansky, Daniel M / Patel, Mitesh S

JAMA network open

2021 Volume 4, Issue 1, Page(s) e2033472

MeSH term(s)	Aged ; Cardiac Rehabilitation ; Decision Support Techniques ; Electronic Health Records ; Female ; Humans ; Inpatients ; Male ; Patient Selection ; Pennsylvania ; Quality Improvement ; Referral and Consultation/statistics & numerical data ; Text Messaging
Language	English
Publishing date	2021-01-04
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ISSN	2574-3805
ISSN (online)	2574-3805
DOI	10.1001/jamanetworkopen.2020.33472
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Article ; Online: Evolution and Outcomes of Premature Coronary Artery Disease.

Smith, Cara Lea / Seigerman, Matthew / Adusumalli, Srinath / Giri, Jay / Fiorilli, Paul N / Kolansky, Daniel M / Kobayashi, Taisei

Current cardiology reports

2021 Volume 23, Issue 4, Page(s) 36

Abstract: Purpose of review: The purpose of this review is to explore the evolution and outcomes of premature coronary artery disease (PCAD) while reviewing strategies for effective screening of those at high risk for developing this disease.: Recent findings: ...

Abstract	Purpose of review: The purpose of this review is to explore the evolution and outcomes of premature coronary artery disease (PCAD) while reviewing strategies for effective screening of those at high risk for developing this disease. Recent findings: Premature coronary artery disease (PCAD) affects a population of patients not typically identified as high risk by current risk stratification guidelines or traditional risk calculation tools. Not only does PCAD represent a large proportion of overall cardiovascular disease, it also afflicts a population in which the rate of mortality from cardiovascular disease has plateaued despite an overall declining population-wide cardiovascular mortality rate. There is ample opportunity for behavioral change strategies, screening tools, adapted imaging modalities, and precision pharmacotherapies to be more precisely targeted toward those at highest risk for premature coronary artery disease. Premature coronary artery disease (PCAD) is pervasive and not frequently represented within contemporary risk calculation models. Providers should pursue proactive screening and aggressive risk factor modification and deploy appropriate preventative therapies in caring for younger populations.
MeSH term(s)	Cardiovascular Diseases ; Coronary Artery Disease ; Humans ; Risk Factors
Language	English
Publishing date	2021-03-08
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2055373-0
ISSN	1534-3170 ; 1523-3782
ISSN (online)	1534-3170
ISSN	1523-3782
DOI	10.1007/s11886-021-01457-8
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Zs.A 5524: Show issues

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Article ; Online: Comparison of Patients Undergoing Percutaneous Coronary Intervention in Contemporary U.S. Practice With ISCHEMIA Trial Population.

Chatterjee, Saurav / Fanaroff, Alexander C / Parzynski, Craig / Curtis, Jeptha / Kolansky, Daniel M / Maddox, Thomas M / Mukherjee, Debabrata / Yeh, Robert W / Giri, Jay

JACC. Cardiovascular interventions

2021 Volume 14, Issue 21, Page(s) 2344–2349

Abstract: Objectives: The study sought to assess the proportion of patients in modern U.S. interventional practice that fulfilled criteria for enrollment in the ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) ...

Abstract	Objectives: The study sought to assess the proportion of patients in modern U.S. interventional practice that fulfilled criteria for enrollment in the ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) trial. Background: The ISCHEMIA trial, which enrolled patients with stable ischemic heart disease (SIHD), showed that revascularization improved angina symptoms with little effect on death or myocardial infarction. Methods: A cross-sectional analysis of the National Cardiovascular Data Registry CathPCI Registry (v5.0), including 1,662 hospitals, was performed. Patients undergoing percutaneous coronary intervention (PCI) for SIHD in routine clinical practice meeting ISCHEMIA trial inclusion criteria and those that did not were evaluated. Results: During the study period, 388,212 patients underwent PCI for SIHD, comprising 41.88% of all patients undergoing PCI during the study period. Of these, 125,302 (32.28%; 13.52% of all patients undergoing PCI) met criteria for enrollment in the ISCHEMIA trial. Among SIHD patients that did not meet criteria, 71,852 (18.51%) had SIHD with high-risk features (35.2% left main disease, 43.7% left ventricular systolic dysfunction, 16.8% end-stage renal disease), 67,159 (17.3%) had SIHD with negative or low-risk functional testing, and 123,899 (31.92%) either had no stress testing or did not have ischemic burden reported. At the median hospital, 32.1% (interquartile range: 23.5%-40.6%) of SIHD patients met criteria for enrollment in the ISCHEMIA trial, with these patients experiencing lower unadjusted in-hospital mortality rate than comparator groups who met exclusion criteria for the trial (0.11%) (P < 0.01 for all comparisons). Conclusions: Among contemporary U.S. patients undergoing PCI for SIHD, 32.28% clearly met enrollment criteria for the ISCHEMIA trial. There was significant variation among individual centers in the proportion of SIHD patients meeting criteria for the ISCHEMIA trial.
MeSH term(s)	Cross-Sectional Studies ; Humans ; Ischemia ; Myocardial Ischemia/diagnostic imaging ; Myocardial Ischemia/therapy ; Percutaneous Coronary Intervention ; Treatment Outcome
Language	English
Publishing date	2021-11-04
Publishing country	United States
Document type	Clinical Trial ; Journal Article
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2021.08.047
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Zs.A 6669: Show issues

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Article ; Online: Trends in Coded Indications for Percutaneous Coronary Interventions in Medicare and the Veterans Affairs After Implementation of Hospital-Level Reporting of Appropriate Use Criteria.

Dayoub, Elias J / Nathan, Ashwin S / Khatana, Sameed Ahmed M / Wadhera, Rishi K / Kolansky, Daniel M / Yeh, Robert W / Giri, Jay / Groeneveld, Peter W

Circulation. Cardiovascular quality and outcomes

2021 Volume 14, Issue 4, Page(s) e006887

Abstract: Background: In 2009, the American College of Cardiology and American Heart Association published Appropriate Use Criteria for Coronary Revascularization (AUC) to aid patient selection for percutaneous coronary intervention (PCI). The subsequent decline ... ...

Abstract	Background: In 2009, the American College of Cardiology and American Heart Association published Appropriate Use Criteria for Coronary Revascularization (AUC) to aid patient selection for percutaneous coronary intervention (PCI). The subsequent decline in inappropriate PCIs was interpreted as a success of AUC. However, there are concerns clinicians reclassify nonacute PCIs to acute indications to fulfill AUC. Methods: A longitudinal, observational difference-in-differences analysis was performed using administrative claims from US Department of Veterans Affairs (VA) beneficiaries coenrolled in Medicare and from a national random sample of Medicare beneficiaries, undergoing PCI from September 30, 2009, to December 31, 2013. Non-VA hospitals participating in the American College of Cardiology CathPCI registry began receiving AUC reports in 2011, while VA hospitals did not receive reports, serving as quasiexperimental and control cohorts, respectively. We measured the proportion of PCIs coded for acute myocardial infarction, unstable angina, and nonacute coronary syndrome indications by quarter. Results: There were 87 464 and 30 251 PCIs performed in the Medicare and VA cohorts, respectively. In Medicare, proportion of PCIs coded for acute myocardial infarction and unstable angina changed from 31.9% and 12.6% in quarter 4 2009 to 41.0% and 10.5% in quarter 4 2013, an associated 2.00% (95% CI, 1.56%-2.44%; Conclusions: After introduction of AUC assessments and reporting, we observed comparable increases in coding for acute myocardial infarction and corresponding decreases in coding for unstable angina and nonacute coronary syndrome indications among national cohorts of Medicare and VA enrollees. The provision of appropriate use reporting did not appear to have a substantial impact on the proportion of PCIs coded for acute indications during this study period.
MeSH term(s)	Aged ; Hospitals, Veterans ; Humans ; Medicare ; Myocardial Infarction ; Percutaneous Coronary Intervention/adverse effects ; Registries ; United States/epidemiology ; Veterans
Language	English
Publishing date	2021-03-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2483197-9
ISSN	1941-7705 ; 1941-7713
ISSN (online)	1941-7705
ISSN	1941-7713
DOI	10.1161/CIRCOUTCOMES.120.006887
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Article ; Online: Attitudes toward pharmacogenetics in patients undergoing

Lee, Grace / Varughese, Lisa A / Conway, Laura / Stojinski, Carol / Ashokkumar, Sandhya / Monono, Karen / Matthai, William / Kolansky, Daniel M / Giri, Jay / Tuteja, Sony

Personalized medicine

2022 Volume 19, Issue 2, Page(s) 93–101

Abstract: Aim: ...

Abstract	Aim:
MeSH term(s)	Attitude ; Cytochrome P-450 CYP2C19/genetics ; Humans ; Percutaneous Coronary Intervention ; Pharmacogenetics/methods ; Pharmacogenomic Testing
Chemical Substances	CYP2C19 protein, human (EC 1.14.14.1) ; Cytochrome P-450 CYP2C19 (EC 1.14.14.1)
Language	English
Publishing date	2022-01-05
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2299146-3
ISSN	1744-828X ; 1741-0541
ISSN (online)	1744-828X
ISSN	1741-0541
DOI	10.2217/pme-2021-0064
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Zs.A 6549: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Safety of Intravenous Cangrelor Administration for Antiplatelet Bridging in Hospitalized Patients: A Retrospective Study.

Johnson, Bryce V / Horton, Edward R / Domenico, Christopher / Nathan, Ashwin S / Fanaroff, Alexander C / Acker, Michael A / Kolansky, Daniel M

The Journal of invasive cardiology

2021 Volume 33, Issue 12, Page(s) E998–E1003

Abstract: Objective: We aimed to characterize outcomes associated with cangrelor administration used in an antiplatelet bridging strategy in real-world clinical scenarios within a large academic medical system.: Background: Cangrelor has been used for ... ...

Abstract	Objective: We aimed to characterize outcomes associated with cangrelor administration used in an antiplatelet bridging strategy in real-world clinical scenarios within a large academic medical system. Background: Cangrelor has been used for antiplatelet bridging in perioperative settings or for patients unable to take oral medications. Prior studies in these settings have reported bleeding rates from 0%-40%. Methods: Patients were retrospectively identified via chart review and included if they were over 18 years old, had coronary or peripheral arterial stents, and had received at least 1 hour of cangrelor infusion during inpatient admission. The primary endpoint was Bleeding Academic Research Consortium (BARC) 3-5 bleeding during cangrelor infusion or within 48 hours of discontinuation; secondary endpoints were bleeding events defined by Thrombolysis in Myocardial Infarction (TIMI), Global Use of Strategies to Open Occluded Arteries (GUSTO), and International Society on Thrombosis and Hemostasis (ISTH) criteria, as well as BARC 2 bleeding. Results: Thirty-one patients met the inclusion criteria. Cangrelor indications were bridging to procedure in 22 patients (71.0%) and inability to take oral P2Y12 inhibitors in 9 patients (29.0%). Twenty-three patients (74.2%) were men, 11 patients (35.5%) were in cardiogenic shock, and 4 patients (12.9%) were on extracorporeal membrane oxygenation (ECMO) at the time of administration. No patients received cangrelor for routine percutaneous coronary intervention. Of the 31 patients, 13 (41.9%) had BARC 3-5 bleeding and 7 (22.6%) expired during hospitalization. All 4 patients on ECMO suffered BARC 3-5 bleeding. Conclusions: We reviewed the use of cangrelor for antiplatelet bridging in real-world clinical scenarios and observed higher rates of clinically significant bleeding than seen in other similar studies. Our study suggests careful consideration when using cangrelor in a sick patient population.
MeSH term(s)	Adenosine Monophosphate/administration & dosage ; Adenosine Monophosphate/adverse effects ; Adenosine Monophosphate/analogs & derivatives ; Adolescent ; Blood Platelets/drug effects ; Humans ; Infusions, Intravenous ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/adverse effects ; Retrospective Studies
Chemical Substances	Platelet Aggregation Inhibitors ; Adenosine Monophosphate (415SHH325A) ; cangrelor (6AQ1Y404U7)
Language	English
Publishing date	2021-11-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	1154372-3
ISSN	1557-2501 ; 1042-3931
ISSN (online)	1557-2501
ISSN	1042-3931
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Zs.A 3701: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Use of Intracardiac Echocardiography During Transvenous Lead Extraction to Avoid a Catastrophic Injury.

Maheshwari, Ankit / Desai, Nimesh D / Giri, Jay / Kobayashi, Taisei / Kolansky, Daniel M / Schaller, Robert D

JACC. Clinical electrophysiology

2019 Volume 5, Issue 6, Page(s) 744–745

MeSH term(s)	Cardiac Imaging Techniques/methods ; Cardiac Resynchronization Therapy Devices ; Device Removal/methods ; Echocardiography/methods ; Electrodes, Implanted/adverse effects ; Humans ; Male ; Middle Aged ; Papillary Muscles/diagnostic imaging ; Postoperative Complications/surgery ; Superior Vena Cava Syndrome/surgery ; Tissue Adhesions/diagnostic imaging ; Tissue Adhesions/etiology ; Tricuspid Valve
Language	English
Publishing date	2019-03-04
Publishing country	United States
Document type	Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't ; Video-Audio Media
ZDB-ID	2846739-5
ISSN	2405-5018 ; 2405-500X ; 2405-500X
ISSN (online)	2405-5018 ; 2405-500X
ISSN	2405-500X
DOI	10.1016/j.jacep.2019.01.013
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