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  1. Article ; Online: Characteristics and analysis of right-to-left shunt-related dizziness in patients without hypoxemia.

    Cao, Liming

    The Journal of international medical research

    2019  Volume 47, Issue 7, Page(s) 2921–2928

    MeSH term(s) Aged ; Dizziness/etiology ; Dizziness/pathology ; Female ; Foramen Ovale, Patent/complications ; Humans ; Hypoxia ; Male ; Middle Aged ; Prognosis
    Language English
    Publishing date 2019-05-27
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 184023-x
    ISSN 1473-2300 ; 0300-0605 ; 0142-2596
    ISSN (online) 1473-2300
    ISSN 0300-0605 ; 0142-2596
    DOI 10.1177/0300060519850940
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 925: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Article ; Online: Post-transfusion severe headache in a patient with thalassemia with superficial siderosis of the central nervous system: a case report and literature review.

    Liu, Xudong / Jiang, Hongliang / Ren, Lijie / Cao, Liming

    BMC neurology

    2024  Volume 24, Issue 1, Page(s) 21

    Abstract: Background: Patients with severe thalassemia may experience adverse effects from transfusion such as fever, rash, and iron overload after long-term transfusion therapy. Severe headaches as a side effect of blood transfusion in patients with thalassemia ... ...

    Abstract Background: Patients with severe thalassemia may experience adverse effects from transfusion such as fever, rash, and iron overload after long-term transfusion therapy. Severe headaches as a side effect of blood transfusion in patients with thalassemia are not commonly observed, especially when combined with superficial siderosis of the central nervous system, which is easily misdiagnosed and requires excessive examination and treatment.
    Case presentation: A 31-year-old woman was admitted with severe headache and vomiting over 3 days following blood transfusion. She was diagnosed with intermediate α-thalassemia at 2 years of age and had a history of irregular blood transfusions. Physical examination revealed horizontal nystagmus with no other abnormal neurological signs. Magnetic resonance (MR) imaging, MR venography, MR arteriography, and cerebrospinal fluid analysis were normal. However, susceptibility-weighted imaging showed abnormal signals in the bilateral and fourth ventricles. Initial antibiotics, antivirals, decompression of intracranial pressure, iron chelation, and symptomatic treatments were administered; subsequently, small intermittent blood transfusions were cautiously administered for severe anemia. The patient's headache was gradually relieved, and she was discharged on day 9. At the 5-month follow-up, the patient's headache recurred following another transfusion.
    Conclusions: Severe post-transfusion headache in patients with thalassemia has not been fully recognized and is easily misdiagnosed, leading to excessive examination and treatment. Understanding the clinical features of transfusion-related headaches can help identify this complication, but the exact pathophysiological mechanism requires further research.
    MeSH term(s) Female ; Humans ; Adult ; Siderosis/complications ; Siderosis/diagnostic imaging ; Central Nervous System ; Thalassemia/complications ; Thalassemia/therapy ; Headache/etiology ; Headache/therapy ; Nystagmus, Pathologic
    Language English
    Publishing date 2024-01-06
    Publishing country England
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 2041347-6
    ISSN 1471-2377 ; 1471-2377
    ISSN (online) 1471-2377
    ISSN 1471-2377
    DOI 10.1186/s12883-024-03526-1
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  3. Article: Clinical analysis of infectious mononucleosis complicated with acute acalculous cholecystitis.

    Gao, Caijie / Cao, Liming / Mei, Xiaoli

    Frontiers in pediatrics

    2024  Volume 12, Page(s) 1339920

    Abstract: Objective: This study aimed to investigate specific clinical diagnostic methods for children with infectious mononucleosis (IM) complicated by acute acalculous cholecystitis (AAC).: Methods: We conducted a retrospective analysis of 171 cases of IM ... ...

    Abstract Objective: This study aimed to investigate specific clinical diagnostic methods for children with infectious mononucleosis (IM) complicated by acute acalculous cholecystitis (AAC).
    Methods: We conducted a retrospective analysis of 171 cases of IM diagnosed in the infectious disease ward of Children's Hospital of Nanjing Medical University between January 2020 and December 2020. All IM patients underwent abdominal ultrasound examinations to assess the liver, gallbladder, and spleen. Fourteen patients with symptoms of AAC underwent a follow-up assessment one week later.
    Results: The estimated incidence of AAC in hospitalized IM children was 8.2%. Both groups of patients presented with fever, abdominal pain, and eyelid edema upon admission. Characteristic radiological findings of AAC were observed, including gallbladder (GB) distention, increased GB wall thickness and increased common bile duct diameter. Analysis of laboratory results revealed no statistically significant differences in leukocyte, absolute lymphocyte count, CD3+, CD3 + CD4+, CD3+ CD8+, Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), or Gamma-Glutamyl Transferase (GGT) levels between the AAC(+) and AAC(-) groups on admission. However, these parameters were not significant risk factors for AAC. After discharge, relevant indicators in non-AAC patients gradually decreased to normal levels, while those in AAC(+) patients did not show a significant decrease.
    Conclusion: While cases of IM complicated by AAC are relatively uncommon, the utilization of abdominal ultrasound offers a reliable tool for confirming this diagnosis. Routine abdominal ultrasound examinations are recommended for IM patients to improve early detection and treatment of associated conditions.
    Language English
    Publishing date 2024-03-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2024.1339920
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  4. Article ; Online: A 19-Bit Small Absolute Matrix Encoder.

    Geng, Liming / Cao, Guohua / Shang, Chunmin / Ding, Hongchang

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 5

    Abstract: With the application of encoders in artificial intelligence and aerospace, the demand for the miniaturization and high measurement accuracy of encoders is increasing. To solve this problem, a new absolute matrix encoder is proposed in this paper, which ... ...

    Abstract With the application of encoders in artificial intelligence and aerospace, the demand for the miniaturization and high measurement accuracy of encoders is increasing. To solve this problem, a new absolute matrix encoder is proposed in this paper, which can realize 19-bit matrix coding by engraving two circles of matrix code, and has the advantages of fewer circles of code disk engraving and higher measurement accuracy. This article mainly focuses on the design of a new matrix code disk, encoding and decoding methods, decoding circuit design, Matlab simulation analysis, and experimental error analysis. The experimental results show that the encoder designed in this paper achieves ultra-small volume Φ30 mm × 20 mm, and the angle measurement accuracy is 2.57".
    Language English
    Publishing date 2024-02-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24051400
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  5. Article: Pulmonary nocardiosis following

    Cao, Liming / Sun, Yilan / Chen, Fei

    Frontiers in medicine

    2023  Volume 10, Page(s) 1266857

    Abstract: Background: Nocardiosis is an opportunistic infection that primarily affects immunocompromised patients. Pulmonary nocardiosis is the most prevalent form, but can also spread to other organs. Potential causes contributing to opportunistic infection may ... ...

    Abstract Background: Nocardiosis is an opportunistic infection that primarily affects immunocompromised patients. Pulmonary nocardiosis is the most prevalent form, but can also spread to other organs. Potential causes contributing to opportunistic infection may include immunosuppression and disruption of tight junctions, both of which can result from
    Case presentation: We reported a case of a 68-year-old male patient who presented with a 10-day history of fever, cough, and productive sputum. Upon physical examination, velcro rales were detected in the right lung, while breath sounds in the left lung were clear. The patient had previously undergone left lung transplantation due to idiopathic pulmonary fibrosis four years ago. He was initially hospitalized and treated for
    Conclusion: This case highlights the complexity of
    Language English
    Publishing date 2023-09-12
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1266857
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  6. Article ; Online: Acute disseminated encephalomyelitis after severe acute respiratory syndrome coronavirus 2 vaccination: a case report.

    Cao, Liming / Ren, Lijie

    Acta neurologica Belgica

    2021  Volume 122, Issue 3, Page(s) 793–795

    MeSH term(s) COVID-19 ; Encephalomyelitis, Acute Disseminated/diagnostic imaging ; Encephalomyelitis, Acute Disseminated/etiology ; Humans ; SARS-CoV-2 ; Vaccination/adverse effects
    Language English
    Publishing date 2021-02-01
    Publishing country Italy
    Document type Case Reports ; Letter
    ZDB-ID 127315-2
    ISSN 2240-2993 ; 0300-9009
    ISSN (online) 2240-2993
    ISSN 0300-9009
    DOI 10.1007/s13760-021-01608-2
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    In stock of ZB MED Cologne/Königswinter

    Ui I Zs.57: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Increased Expression of

    Deng, Pengbo / Zhou, Rongrong / Zhang, Jinghui / Cao, Liming

    Journal of Cancer

    2021  Volume 12, Issue 11, Page(s) 3239–3248

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2021-04-02
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2573318-7
    ISSN 1837-9664
    ISSN 1837-9664
    DOI 10.7150/jca.51591
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  8. Article: Novel heterozygous mutation in

    Qiu, Guozhen / Cao, Liming / Chen, Yong-Jun

    Frontiers in neurology

    2023  Volume 13, Page(s) 1090900

    Abstract: Introduction: Many studies have suggested that the alpha-2-macroglobulin (: Methods: The patient in this study had progressive memory loss at the age of 60 years and underwent a series of neuropsychological tests, cranial magnetic resonance imaging ( ... ...

    Abstract Introduction: Many studies have suggested that the alpha-2-macroglobulin (
    Methods: The patient in this study had progressive memory loss at the age of 60 years and underwent a series of neuropsychological tests, cranial magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) biomarker analysis, and whole-exome sequencing (WES) to evaluate possible mutations. We used in silico tools and three-dimensional (3D) protein structure prediction to analyze the pathogenicity of the mutation and used a co-immunoprecipitation experiment to study the effect of mutations on amyloid-β (Aβ) binding.
    Results: Based on neuropsychological tests, cranial MRI, and CSF biomarker analysis, the patient was diagnosed with AD. WES showed that there was a missense mutation in
    Conclusions: Our results demonstrate that this novel A2M p.N410T mutation may have a pathogenic role in AD, by altering the binding interactions between A2M and Aβ.
    Language English
    Publishing date 2023-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2022.1090900
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  9. Article: Characterization of size-resolved effective density of atmospheric particles in an urban atmosphere in Southern China.

    Xie, Tingting / Cao, Liming / Zheng, Jinyi / Xuan, Peng / Huang, Xiaofeng

    Journal of environmental sciences (China)

    2023  Volume 141, Page(s) 194–204

    Abstract: Effective density ( ... ...

    Abstract Effective density (ρ
    MeSH term(s) Air Pollutants/analysis ; Particulate Matter/analysis ; Particle Size ; Aerosols/analysis ; Atmosphere ; China ; Environmental Monitoring/methods
    Chemical Substances Air Pollutants ; Particulate Matter ; Aerosols
    Language English
    Publishing date 2023-09-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1092300-7
    ISSN 1878-7320 ; 1001-0742
    ISSN (online) 1878-7320
    ISSN 1001-0742
    DOI 10.1016/j.jes.2023.09.021
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    In stock of ZB MED Bonn / Germany

    Z 7630: Show issues

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  10. Article ; Online: TECPR1 Induces Apoptosis in Non-Small Cell Lung Carcinoma via ATG5 Upregulation-Induced Autophagy Promotion.

    Cao, Liming / Lin, Fan

    Annals of clinical and laboratory science

    2022  Volume 52, Issue 4, Page(s) 580–592

    Abstract: Objective: Non-small cell lung carcinoma (NSCLC) is a subtype of lung cancer with unfavorable outcome. Autophagy, a mechanism responsible for cellular component degradation, has been recorded to play either a positive or negative regulatory role in ... ...

    Abstract Objective: Non-small cell lung carcinoma (NSCLC) is a subtype of lung cancer with unfavorable outcome. Autophagy, a mechanism responsible for cellular component degradation, has been recorded to play either a positive or negative regulatory role in apoptosis. Tectonin Beta-Propeller Repeat Containing 1 (TECPR1) is recognized relevant to autophagy. This study aimed to investigate the molecular mechanisms through which TECPR1 regulates NSCLC cell apoptosis.
    Methods: Analysis of TECPR1 expression in the subcategories of NSCLC was conducted using GEPIA. Survival analysis for NSCLC patients was performed with Kaplan-Meier's plotter. The interaction between ATG5 and TECPR1 was predicted by STRING and validated through co-immunoprecipitation. NSCLC cells were transfected with short hairpin RNA against ATG5 and/or ATG5/TECPR1 overexpression plasmids, followed by viability and apoptosis assay using CCK-8 and flow cytometry. Expressions of TECPR1, ATG5, LC3-II/LC3-I, P62, B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax) in NSCLC cells with or without transfection were assessed by qRT-PCR and/or Western blot.
    Results: TECPR1 was low-expressed in LUAD and LUSC samples as well as NSCLC cells. Higher TECPR1 expression was associated with better outcomes. TECPR1 overexpression and ATG5 overexpression both decreased viability, promoted apoptosis, upregulated Bax and LC3-II/LC3-I, and downregulated P62 and Bcl-2. TECPR1 could form a complex with ATG5 in NSCLC cells. ATG5 was upregulated by TECPR1 overexpression and could positively modulate TECPR1 expression. ATG5 knockdown induced effect oppositely to TECPR1 overexpression, and this effect reversed the TECPR1 overexpression-induced effect and vice versa.
    Conclusion: TECPR1 induces NSCLC cell apoptosis via ATG5 upregulation-induced autophagy promotion.
    MeSH term(s) Apoptosis/genetics ; Autophagy ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 5/metabolism ; Autophagy-Related Protein 5/pharmacology ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/metabolism ; Humans ; Lung Neoplasms/genetics ; Membrane Proteins/genetics ; RNA, Small Interfering ; Sincalide/genetics ; Sincalide/metabolism ; Sincalide/pharmacology ; Up-Regulation/genetics ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; bcl-2-Associated X Protein/pharmacology
    Chemical Substances ATG5 protein, human ; Autophagy-Related Protein 5 ; Membrane Proteins ; RNA, Small Interfering ; TECPR1 protein, human ; bcl-2-Associated X Protein ; Sincalide (M03GIQ7Z6P)
    Language English
    Publishing date 2022-10-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193092-8
    ISSN 1550-8080 ; 0091-7370 ; 0095-8905
    ISSN (online) 1550-8080
    ISSN 0091-7370 ; 0095-8905
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 942: Show issues Location:
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