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  1. Article: OTWorldNews. Auf nach Leipzig, auf nach Hause! Interview mit Prof. Dr. Thomas Wirth und Dipl.-Ing.(FH) Ingo Pfefferkorn

    Wirth, Thomas / Pfefferkorn, Ingo

    Orthopädie-Technik

    2023  Volume 74, Issue 9, Page(s) 32

    Language German
    Document type Article
    ZDB-ID 207441-2
    ISSN 0340-5591
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Clinical applications of circulating HBV RNA as a potential surrogate biomarker for intrahepatic cccDNA transcriptional activity.

    Yu, Xiaoqi / Pfefferkorn, Maria / van Bömmel, Florian / Zhang, Xinxin / Berg, Thomas

    Gut

    2024  Volume 73, Issue 4, Page(s) 563–566

    MeSH term(s) Humans ; Hepatitis B virus/genetics ; Hepatitis B Surface Antigens ; Hepatitis B e Antigens ; Biomarkers ; RNA ; DNA, Viral/genetics ; DNA, Circular ; Liver
    Chemical Substances Hepatitis B Surface Antigens ; Hepatitis B e Antigens ; Biomarkers ; RNA (63231-63-0) ; DNA, Viral ; DNA, Circular
    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2023-331217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Reinigung von tumorzellkontaminiertem Operationsblut mit Leukozytendepletionsfiltern im Hinblick auf die autologe Transfusion in der Tumorchirurgie

    Pfefferkorn, Thomas

    1996  

    Author's details vorgelegt von Thomas Pfefferkorn
    Language German
    Size 52 S. : Ill.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Univ., Diss., 1996
    HBZ-ID HT007370227
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    96 D 3711 order for loan Magazin

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  4. Article: CME Zertifizierte Fortbildung. Sinus-Venen-Thrombose. Bei Verdacht gezielt nach venösem Verschluss fahnden / CME-Fragen

    Pfefferkorn, Thomas

    InFo Neurologie & Psychiatrie

    2018  Volume 20, Issue 12, Page(s) 28/34

    Language German
    Document type Article
    ZDB-ID 2008542-4
    ISSN 1437-062X
    Database Current Contents Medicine

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    Zs.A 5176: Show issues Location:
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  5. Article ; Online: Weight Loss After Bariatric Surgery in Different Age Groups.

    Pfefferkorn, Urs / Hort, Sabrina / Beluli, Melika / La Vista, Monica / Züger, Thomas

    Obesity surgery

    2023  Volume 33, Issue 4, Page(s) 1154–1159

    Abstract: Purpose: Weight loss after bariatric operations may be reduced in older patients due to changes in metabolism. Some studies showed inferior weight loss in older patients compared to younger ones while others showed no such difference. In order to ... ...

    Abstract Purpose: Weight loss after bariatric operations may be reduced in older patients due to changes in metabolism. Some studies showed inferior weight loss in older patients compared to younger ones while others showed no such difference. In order to counsel patients about the expected weight loss after bariatric surgery, recommendations stratified by age are important.
    Methods: This study encompasses a retrospective analysis of 500 consecutive patients with RYGB or sleeve gastrectomies from a single institution with a mean follow-up time of 3.6 years. Patients were stratified into five groups according to age at the time point of the operation: < 30 years, 30-39 years, 40-49 years, 50-59 years, and ≥ 60 years.
    Results: Weight loss expressed in percent excessive body mass index loss (%EBMIL) at nadir were 86.6, 89.5, 84.0, 77.9, and 76.4% and 75.6, 78.4, 73.3, 68.0, and 69.0% at the time of last follow-up for the five groups, respectively. Weight loss was significantly higher in younger patients than in older patients for both time points. The total number of comorbidities that showed complete remission (normal values without treatment), was also significantly higher in the younger age groups.
    Conclusions: Primary bariatric operations yield better weight loss results and remission rates of obesity related comorbidities in younger patients, but are still effective in older individuals.
    MeSH term(s) Humans ; Aged ; Obesity, Morbid/surgery ; Gastric Bypass/methods ; Retrospective Studies ; Bariatric Surgery ; Weight Loss ; Gastrectomy/methods ; Body Mass Index ; Treatment Outcome
    Language English
    Publishing date 2023-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-023-06488-4
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  6. Article ; Online: Brainstem encephalitis in neuroborreliosis: typical clinical course and distinct MRI findings.

    Pfefferkorn, Thomas / Röther, Joachim / Eckert, Bernd / Janssen, Hendrik

    Journal of neurology

    2020  Volume 268, Issue 2, Page(s) 502–505

    Abstract: Objective: In this retrospective observational study and referring to a historical case presented in 2009, we searched for typical clinical and imaging features of brainstem encephalitis in neuroborreliosis.: Methods: In addition to the historical ... ...

    Abstract Objective: In this retrospective observational study and referring to a historical case presented in 2009, we searched for typical clinical and imaging features of brainstem encephalitis in neuroborreliosis.
    Methods: In addition to the historical case we describe five affected patients.
    Results: All patients had a very similar prolonged clinical course with unspecific symptoms such as wasting, fatigue and headache. Brainstem signs were irregularly observed. MRI showed symmetrical brainstem alterations in all patients. In coronary FLAIR imaging these changes formed a figure resembling a Philippine tarsier.
    Conclusions: A subset of patients with neuroborreliosis develops a brainstem encephalitis with a typical clinical course and distinct MRI findings.
    MeSH term(s) Brain Stem/diagnostic imaging ; Encephalitis/diagnostic imaging ; Headache ; Humans ; Magnetic Resonance Imaging ; Nervous System Diseases
    Language English
    Publishing date 2020-08-28
    Publishing country Germany
    Document type Journal Article ; Observational Study
    ZDB-ID 187050-6
    ISSN 1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    ISSN (online) 1432-1459
    ISSN 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    DOI 10.1007/s00415-020-10188-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Conference proceedings: Generation of HBV DNA Plasmids of Genotype E for In Vitro Infection Model

    Wouambo, Rodrigue Kamga / Lehmann, Felix / Pfefferkorn, Maria / Matz-Soja, Madlen / Glebe, Dieter / Berg, Thomas / van Bömmel, Florian

    Zeitschrift für Gastroenterologie

    2024  Volume 62, Issue 01

    Event/congress 40. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber, Haus der Technik e.V., Essen, 2024-01-26
    Language German
    Publishing date 2024-01-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0044-2771 ; 0172-8504
    ISSN (online) 1439-7803
    ISSN 0044-2771 ; 0172-8504
    DOI 10.1055/s-0043-1777654
    Database Thieme publisher's database

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  8. Article: Die primäre ZNS-Vaskulitis und ihre Differentialdiagnosen

    Pfefferkorn, Thomas

    Der bayerische Internist

    2014  Volume 34, Issue 3, Page(s) 30

    Language German
    Document type Article
    ZDB-ID 632522-1
    ISSN 0176-4993
    Database Current Contents Medicine

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  9. Article: The Role of NOX2-Derived Reactive Oxygen Species in the Induction of Endothelin-Converting Enzyme-1 by Angiotensin II.

    Adu-Gyamfi, Michael / Goettsch, Claudia / Kamhieh-Milz, Julian / Chen, Lei / Pfefferkorn, Anna Maria / Hofmann, Anja / Brunssen, Coy / Müller, Gregor / Walther, Thomas / Ashraf, Muhammad Imtiaz / Morawietz, Henning / Witowski, Janusz / Catar, Rusan

    Antioxidants (Basel, Switzerland)

    2024  Volume 13, Issue 4

    Abstract: Endothelin-1 is a key regulator of vascular tone and blood pressure in health and disease. We have recently found that ET-1 production in human microvascular endothelial cells (HMECs) can be promoted by angiotensin II (Ang II) through a novel mechanism ... ...

    Abstract Endothelin-1 is a key regulator of vascular tone and blood pressure in health and disease. We have recently found that ET-1 production in human microvascular endothelial cells (HMECs) can be promoted by angiotensin II (Ang II) through a novel mechanism involving octamer-binding transcription factor-1 (Oct-1), NADPH oxidase-2 (NOX2), and superoxide anions. As the formation of bioactive ET-1 also depends on endothelin-converting enzyme-1 (ECE-1), we investigated the transcriptional regulation of the
    Language English
    Publishing date 2024-04-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox13040500
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  10. Article ; Online: Telemedical stroke care significantly improves patient outcome in rural areas: Long-term analysis of the German NEVAS network.

    Masouris, Ilias / Kellert, Lars / Pradhan, Cauchy / Wischmann, Johannes / Schniepp, Roman / Müller, Robert / Fuhry, Leonard / Hamann, Gerhard F / Pfefferkorn, Thomas / Rémi, Jan M / Schöberl, Florian

    International journal of stroke : official journal of the International Stroke Society

    2024  , Page(s) 17474930241234259

    Abstract: Background: Comprehensive stroke centers (CSC) offer state-of-the-art stroke care in metropolitan centers. However, in rural areas, sufficient stroke expertise is much scarcer. Recently, telemedical stroke networks have offered instant consultation by ... ...

    Abstract Background: Comprehensive stroke centers (CSC) offer state-of-the-art stroke care in metropolitan centers. However, in rural areas, sufficient stroke expertise is much scarcer. Recently, telemedical stroke networks have offered instant consultation by stroke experts, enabling immediate administration of intravenous thrombolysis (IVT) on-site and decision on thrombectomy. While these immediate decisions are made during the consult, the impact of the network structures on stroke care in spoke hospitals is still not well described.
    Aims: This study was performed to determine if on-site performance in rural hospitals and patient outcome improve over time through participation and regular medical staff training within a telemedical stroke network.
    Methods: In this retrospective study, we analyzed data from stroke patients treated in four regional hospitals within the telemedical Neurovascular Network of Southwest Bavaria (NEVAS) between 2014 and 2019. We only included those patients that were treated in the regional hospitals until discharge at home or to neurorehabilitation. Functional outcome (modified Rankin scale) at discharge, mortality rate and periprocedural intracranial hemorrhage served as primary outcome parameters. Door-to-imaging and door-to-needle times were secondary outcome parameters.
    Results: In 2014-2019, 5,379 patients were treated for acute stroke with 477 receiving IVT. Most baseline characteristics were comparable over time. For all stroke patients, door-to-imaging times increased over the years, but significantly improved for potential IVT candidates and those finally treated with IVT. The percentage of patients with door-to-needle time <30 min increased from 10% to 25%. Clinical outcome at discharge improved for all stroke patients treated in the regional hospitals. Particularly for patients treated with IVT, good clinical outcome (modified Rankin scale 0-2) at discharge increased from 2014 to 2019 by 19% and mortality rates dropped from 13% to 5%.
    Conclusions: 24-h/7-day telemedical support and regular on-site medical staff training within a structured telemedicine stroke network such as NEVAS significantly improve on-site stroke care in rural areas, leading to a considerable benefit in clinical outcome.
    Data access statement: The data that support the findings of this study are available upon reasonable request and in compliance with the local and international ethical guidelines.
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2303728-3
    ISSN 1747-4949 ; 1747-4930
    ISSN (online) 1747-4949
    ISSN 1747-4930
    DOI 10.1177/17474930241234259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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