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  1. Book ; Thesis: Netzhautdickenmessung mit dem Heidelberger Retina-Tomograph bei Patienten mit Makulaödem und bei Gesunden

    Ackermann, Andreas

    2013  

    Author's details von Andreas Ackermann
    Language German
    Size 79 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dresden, Techn. Univ., Diss., 2013
    HBZ-ID HT018213731
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Lehrbuch für präklinische Notfallmedizin / Band 1

    Ackermann, Ralf / Enke, Kersten / Flemming, Andreas / Hündorf, Hans-Peter / Knacke, Peer G. / Lipp, Roland / Rupp, Peter

    2019  

    Title variant LPN 1
    Author's details Herausgeber Kersten Enke, Andreas Flemming, Hans-Peter Hündorf, Peer G. Knacke, Roland Lipp, Peter Rupp
    Collection Lehrbuch für präklinische Notfallmedizin
    Language German
    Size XXIV, 716 Seiten, Illustrationen, Diagramme
    Edition 6. Auflage
    Publishing country Germany
    Document type Book
    Accompanying material Zugang zur Internetausgabe über Code
    HBZ-ID HT020193118
    ISBN 978-3-96461-011-9 ; 3-96461-011-9
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Computergestützte Detektion unerwünschter Arzneimittelwirkungen auf der Basis von Laborwerten, Medikation und Diagnosen

    Ackermann, Andreas

    2007  

    Author's details vorgelegt von Andreas Ackermann
    Language German
    Size 127 : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Erlangen, Nürnberg, Univ., Diss., 2007
    HBZ-ID HT015385253
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Umweltverträgliches Naherholungskonzept für die Burgdorfer Aue

    Ackermann, Andreas

    (Beiträge zur regionalen Entwicklung ; 102)

    2003  

    Author's details im Auftr. der Region Hannover sowie der Städte Burgdorf, Lehrte, Sehnde und der Gemeinde Uetze. Bearb.: Andreas Ackermann
    Series title Beiträge zur regionalen Entwicklung ; 102
    Collection
    Language German
    Size 51 S., Ill., Kt., 30 cm
    Publisher Region Hannover
    Publishing place Hannover
    Publishing country Germany
    Document type Book
    Accompanying material Maßnahmenpl. ([1] Bl.)
    HBZ-ID HT014126521
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  5. Book ; Thesis: Empirische Untersuchungen in der stationären Altenhilfe

    Ackermann, Andreas

    Relevanz und methodische Besonderheiten der gerontologischen Interventionsforschung mit Pflegeheimbewohnern

    (Erlanger Beiträge zur Gerontologie ; 4)

    2005  

    Institution Friedrich-Alexander-Universität Erlangen-Nürnberg
    Author's details Andreas Ackermann
    Series title Erlanger Beiträge zur Gerontologie ; 4
    Collection
    Keywords Stationäre Altenhilfe ; Empirische Forschung ; Altenheimbewohner ; Gerontologie
    Subject Altenforschung ; Alternsforschung ; Altersforschung ; Alterskunde ; Altenheim
    Language German
    Size 236 Seiten, Illustrationen, Diagramme
    Publisher Lit
    Publishing place Münster
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Erlangen-Nürnberg, 2004
    HBZ-ID HT014413568
    ISBN 3-8258-8579-8 ; 978-3-8258-8579-3
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Pleiotropic hubs drive bacterial surface competition through parallel changes in colony composition and expansion.

    van Gestel, Jordi / Wagner, Andreas / Ackermann, Martin

    PLoS biology

    2023  Volume 21, Issue 10, Page(s) e3002338

    Abstract: Bacteria commonly adhere to surfaces where they compete for both space and resources. Despite the importance of surface growth, it remains largely elusive how bacteria evolve on surfaces. We previously performed an evolution experiment where we evolved ... ...

    Abstract Bacteria commonly adhere to surfaces where they compete for both space and resources. Despite the importance of surface growth, it remains largely elusive how bacteria evolve on surfaces. We previously performed an evolution experiment where we evolved distinct Bacilli populations under a selective regime that favored colony spreading. In just a few weeks, colonies of Bacillus subtilis showed strongly advanced expansion rates, increasing their radius 2.5-fold relative to that of the ancestor. Here, we investigate what drives their rapid evolution by performing a uniquely detailed analysis of the evolutionary changes in colony development. We find mutations in diverse global regulators, RicT, RNAse Y, and LexA, with strikingly similar pleiotropic effects: They lower the rate of sporulation and simultaneously facilitate colony expansion by either reducing extracellular polysaccharide production or by promoting filamentous growth. Combining both high-throughput flow cytometry and gene expression profiling, we show that regulatory mutations lead to highly reproducible and parallel changes in global gene expression, affecting approximately 45% of all genes. This parallelism results from the coordinated manner by which regulators change activity both during colony development-in the transition from vegetative growth to dormancy-and over evolutionary time. This coordinated activity can however also break down, leading to evolutionary divergence. Altogether, we show how global regulators function as major pleiotropic hubs that drive rapid surface adaptation by mediating parallel changes in both colony composition and expansion, thereby massively reshaping gene expression.
    MeSH term(s) Mutation ; Bacteria ; Gene Expression Profiling
    Language English
    Publishing date 2023-10-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2126776-5
    ISSN 1545-7885 ; 1544-9173
    ISSN (online) 1545-7885
    ISSN 1544-9173
    DOI 10.1371/journal.pbio.3002338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Managing One-Lung Ventilation in Tracheostomized Patients: A 6-Year Retrospective Analysis.

    Golditz, Tobias / Schmidt, Joachim / Ackermann, Andreas / Danzl, Anja / Birkholz, Torsten / Sirbu, Horia / Irouschek, Andrea

    The Thoracic and cardiovascular surgeon

    2024  

    Abstract: Background:  To ensure safe and optimal surgical conditions in thoracic surgery, one-lung ventilation is crucial. Various techniques exist to achieve one-lung ventilation. Tracheotomized patients who require one-lung ventilation represent a unique and ... ...

    Abstract Background:  To ensure safe and optimal surgical conditions in thoracic surgery, one-lung ventilation is crucial. Various techniques exist to achieve one-lung ventilation. Tracheotomized patients who require one-lung ventilation represent a unique and rare subgroup that demands specialized knowledge and skills. The very limited literature has discussed alternative methods, no randomized controlled trials have addressed this issue yet.
    Methods:  We performed a retrospective analysis of patients who underwent one-lung ventilation in the Department of Thoracic Surgery of a German University Hospital between 2016 and 2021. The study assessed patient demographics, airway management techniques, ventilation parameters, and adverse events.
    Results:  In 3,197 anesthesia procedures during the observation period, 152 patients had an existing tracheostomy, of which 56 required one-lung ventilation. Among others in 42 cases, a tracheostomy tube was combined with a bronchial blocker, and in 10 cases, a double-lumen tracheostomy tube was used. There were no severe complications. Intraoperative dislocations that required repositioning of the device occurred in six patients (13.3%) with bronchial blockers and one patient with double-lumen tracheostomy tube (10%).
    Conclusion:  The management of one-lung ventilation in tracheotomized patients presents unique challenges. While double-lumen tracheostomy tubes have specific advantages, we recommend considering their use carefully. For most tracheotomized patients, bronchial blockers in conjunction with a tracheostomy tube are used, which offers safety and practicality, irrespective of the tracheostomy's age or type. Further research and randomized controlled trials are warranted to establish best practices for one-lung ventilation in this unique patient population.
    Language English
    Publishing date 2024-04-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 800050-5
    ISSN 1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
    ISSN (online) 1439-1902
    ISSN 0171-6425 ; 0946-4778 ; 0172-6137
    DOI 10.1055/s-0044-1782684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Fate of

    Holzmann, Hannah / Claßen, Daniela / Ackermann, Juliane / Schäffer, Andreas

    Chemosphere

    2022  Volume 303, Issue Pt 1, Page(s) 134885

    Abstract: The persistence assessment of organic chemicals is based on neutral reference substances. Therefore, our study aimed at investigating the influence of a chemical charge on the degradation of organic compounds in a water-sediment system (OECD 308) and ... ...

    Abstract The persistence assessment of organic chemicals is based on neutral reference substances. Therefore, our study aimed at investigating the influence of a chemical charge on the degradation of organic compounds in a water-sediment system (OECD 308) and surface water (OECD 309). We used radiolabelled 4-n-dodecylbenzenesulfonic acid sodium salt (
    MeSH term(s) Cations ; Geologic Sediments/chemistry ; Organic Chemicals ; Water/chemistry ; Water Pollutants, Chemical/analysis
    Chemical Substances Cations ; Organic Chemicals ; Water Pollutants, Chemical ; Water (059QF0KO0R)
    Language English
    Publishing date 2022-05-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2022.134885
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online ; Thesis: Laborbasierte Analyse des Hepatitis-B- und HIV-Status der asylsuchenden Population in Bayern in den Jahren 2015 bis 2017

    Ackermann, Swetlana [Verfasser] / Sing, Andreas [Akademischer Betreuer]

    2023  

    Author's details Swetlana Ackermann ; Betreuer: Andreas Sing
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  10. Article ; Online: Pleiotropic hubs drive bacterial surface competition through parallel changes in colony composition and expansion.

    Jordi van Gestel / Andreas Wagner / Martin Ackermann

    PLoS Biology, Vol 21, Iss 10, p e

    2023  Volume 3002338

    Abstract: Bacteria commonly adhere to surfaces where they compete for both space and resources. Despite the importance of surface growth, it remains largely elusive how bacteria evolve on surfaces. We previously performed an evolution experiment where we evolved ... ...

    Abstract Bacteria commonly adhere to surfaces where they compete for both space and resources. Despite the importance of surface growth, it remains largely elusive how bacteria evolve on surfaces. We previously performed an evolution experiment where we evolved distinct Bacilli populations under a selective regime that favored colony spreading. In just a few weeks, colonies of Bacillus subtilis showed strongly advanced expansion rates, increasing their radius 2.5-fold relative to that of the ancestor. Here, we investigate what drives their rapid evolution by performing a uniquely detailed analysis of the evolutionary changes in colony development. We find mutations in diverse global regulators, RicT, RNAse Y, and LexA, with strikingly similar pleiotropic effects: They lower the rate of sporulation and simultaneously facilitate colony expansion by either reducing extracellular polysaccharide production or by promoting filamentous growth. Combining both high-throughput flow cytometry and gene expression profiling, we show that regulatory mutations lead to highly reproducible and parallel changes in global gene expression, affecting approximately 45% of all genes. This parallelism results from the coordinated manner by which regulators change activity both during colony development-in the transition from vegetative growth to dormancy-and over evolutionary time. This coordinated activity can however also break down, leading to evolutionary divergence. Altogether, we show how global regulators function as major pleiotropic hubs that drive rapid surface adaptation by mediating parallel changes in both colony composition and expansion, thereby massively reshaping gene expression.
    Keywords Biology (General) ; QH301-705.5
    Subject code 612
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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