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Article ; Online: m

2022 Volume 41, Issue 4, Page(s) 111546

Abstract: Human papillomavirus (HPV)-induced carcinogenesis critically depends on the viral early protein 7 (E7), making E7 an attractive therapeutic target. Here, we report that the E7 messenger RNA (mRNA)-containing oncotranscript complex can be selectively ... ...

Abstract	Human papillomavirus (HPV)-induced carcinogenesis critically depends on the viral early protein 7 (E7), making E7 an attractive therapeutic target. Here, we report that the E7 messenger RNA (mRNA)-containing oncotranscript complex can be selectively targeted by heat treatment. In HPV-infected cells, viral E7 mRNA is modified by N
MeSH term(s)	Humans ; Alphapapillomavirus/metabolism ; Carcinogenesis ; Heat-Shock Proteins ; Heat-Shock Response ; Papillomaviridae ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; Papillomavirus Infections ; Proteasome Endopeptidase Complex ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Viral/genetics ; Ubiquitin ; RNA-Binding Proteins
Chemical Substances	Heat-Shock Proteins ; Papillomavirus E7 Proteins ; Proteasome Endopeptidase Complex (EC 3.4.25.1) ; RNA, Messenger ; RNA, Viral ; Ubiquitin ; RNA-Binding Proteins
Language	English
Publishing date	2022-10-23
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2649101-1
ISSN	2211-1247 ; 2211-1247
ISSN (online)	2211-1247
ISSN	2211-1247
DOI	10.1016/j.celrep.2022.111546
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Article ; Online: The human mitochondrial 12S rRNA m

Chen, Hao / Shi, Zhennan / Guo, Jiaojiao / Chang, Kao-Jung / Chen, Qianqian / Yao, Cong-Hui / Haigis, Marcia C / Shi, Yang

The Journal of biological chemistry

2020 Volume 295, Issue 25, Page(s) 8505–8513

Abstract: Mitochondrial DNA gene expression is coordinately regulated both pre- and post-transcriptionally, and its perturbation can lead to human pathologies. Mitochondrial rRNAs (mt-rRNAs) undergo a series of nucleotide modifications after release from ... ...

Abstract	Mitochondrial DNA gene expression is coordinately regulated both pre- and post-transcriptionally, and its perturbation can lead to human pathologies. Mitochondrial rRNAs (mt-rRNAs) undergo a series of nucleotide modifications after release from polycistronic mitochondrial RNA precursors, which is essential for mitochondrial ribosomal biogenesis. Cytosine
MeSH term(s)	CRISPR-Cas Systems/genetics ; Escherichia coli Proteins/metabolism ; Evolution, Molecular ; Gene Editing ; Genome, Mitochondrial ; Glycolysis ; Humans ; Kinetics ; Methylation ; Methyltransferases/genetics ; Methyltransferases/metabolism ; Microscopy, Fluorescence ; Mitochondria/genetics ; Mitochondria/metabolism ; RNA, Messenger/metabolism ; RNA, Mitochondrial/metabolism ; RNA, Ribosomal/genetics ; RNA, Ribosomal/metabolism ; Substrate Specificity
Chemical Substances	Escherichia coli Proteins ; RNA, Messenger ; RNA, Mitochondrial ; RNA, Ribosomal ; RNA, ribosomal, 12S ; mitochondrial messenger RNA ; Methyltransferases (EC 2.1.1.-) ; RsmH protein, E coli (EC 2.1.1.-)
Language	English
Publishing date	2020-05-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2997-x
ISSN	1083-351X ; 0021-9258
ISSN (online)	1083-351X
ISSN	0021-9258
DOI	10.1074/jbc.RA119.012127
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Article ; Online: The cooperation of cis-elements during M-cadherin promoter activation.

Lin, Yung-Jui / Kao, Chien-Han / Hsiao, Sheng-Pin / Chen, Shen-Liang

The Biochemical journal

2021 Volume 478, Issue 4, Page(s) 911–926

Abstract: M-cadherin is a skeletal muscle-specific transmembrane protein mediating the cell-cell adhesion ... boxes, 2 GC boxes, and 1 conserved downstream element (CDE) were identified in the M-cadherin proximal ... activation by MyoD, suggesting an essential collaboration between E-boxes. Stronger activation of M-cadherin ...

Abstract	M-cadherin is a skeletal muscle-specific transmembrane protein mediating the cell-cell adhesion of myoblasts during myogenesis. It is expressed in the proliferating satellite cells and highly induced by myogenic regulatory factors (MRFs) during terminal myogenic differentiation. Several conserved cis-elements, including 5 E-boxes, 2 GC boxes, and 1 conserved downstream element (CDE) were identified in the M-cadherin proximal promoter. We found that E-box-3 and -4 close to the transcription initiation site (TIS) mediated most of its transactivation by MyoD, the strongest myogenic MRF. Including of any one of the other E-boxes restored the full activation by MyoD, suggesting an essential collaboration between E-boxes. Stronger activation of M-cadherin promoter than that of muscle creatine kinase (MCK) by MyoD was observed regardless of culture conditions and the presence of E47. Furthermore, MyoD/E47 heterodimer and MyoD ∼ E47 fusion protein achieved similar levels of activation in differentiation medium (DM), suggesting high affinity of MyoD/E47 to E-boxes 3/4 under DM. We also found that GC boxes and CDE positively affected MyoD mediated activation. The CDE element was predicted to be the target of the chromatin-modifying factor Meis1/Pbx1 heterodimer. Knockdown of Pbx1 significantly reduced the expression level of M-cadherin, but increased that of N-cadherin. Using ChIP assay, we further found significant reduction in MyoD recruitment to M-cadherin promoter when CDE was deleted. Taken together, these observations suggest that the chromatin-modifying function of Pbx1/Meis1 is critical to M-cadherin promoter activation before MyoD is recruited to E-boxes to trigger transcription.
MeSH term(s)	Animals ; Base Sequence ; Cadherins/genetics ; Cells, Cultured ; Conserved Sequence ; E-Box Elements/genetics ; Fibroblasts ; Gene Expression Regulation/genetics ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Mice ; Muscle Development/genetics ; Myeloid Ecotropic Viral Integration Site 1 Protein/physiology ; MyoD Protein/metabolism ; Myoblasts ; Pre-B-Cell Leukemia Transcription Factor 1/physiology ; Promoter Regions, Genetic/genetics ; RNA Interference ; RNA, Small Interfering/genetics ; RNA, Small Interfering/pharmacology ; Recombinant Proteins/metabolism ; Sequence Alignment ; Sequence Homology, Nucleic Acid
Chemical Substances	Cadherins ; Meis1 protein, mouse ; Myeloid Ecotropic Viral Integration Site 1 Protein ; MyoD Protein ; MyoD1 myogenic differentiation protein ; Pbx1 protein, mouse ; Pre-B-Cell Leukemia Transcription Factor 1 ; RNA, Small Interfering ; Recombinant Proteins ; M-cadherin (142845-03-2)
Language	English
Publishing date	2021-02-01
Publishing country	England
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2969-5
ISSN	1470-8728 ; 0006-2936 ; 0306-3275 ; 0264-6021
ISSN (online)	1470-8728
ISSN	0006-2936 ; 0306-3275 ; 0264-6021
DOI	10.1042/BCJ20200535
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Article ; Online: Small Structural Proteins E and M Render the SARS-CoV-2 Pseudovirus More Infectious and Reveal the Phenotype of Natural Viral Variants.

Wang, Hsin-I / Chuang, Zih-Shiuan / Kao, Yu-Ting / Lin, Yi-Ling / Liang, Jian-Jong / Liao, Chun-Che / Liao, Ching-Len / Lai, Michael M C / Yu, Chia-Yi

International journal of molecular sciences

2021 Volume 22, Issue 16

Abstract: ... envelope (E), and membrane (M) proteins together wrap up the SARS-CoV-2 virion, most of the reported ... pseudotype viruses consist of only the S protein. Here, we report that the presence of E and M increased ... the virion infectivity by promoting the S protein priming. The S, E, and M (SEM)-coated pseudovirion is ...

Abstract	The SARS-CoV-2 pseudovirus is a commonly used strategy that mimics certain biological functions of the authentic virus by relying on biological legitimacy at the molecular level. Despite the fact that spike (S), envelope (E), and membrane (M) proteins together wrap up the SARS-CoV-2 virion, most of the reported pseudotype viruses consist of only the S protein. Here, we report that the presence of E and M increased the virion infectivity by promoting the S protein priming. The S, E, and M (SEM)-coated pseudovirion is spherical, containing crown-like spikes on the surface. Both S and SEM pseudoviruses packaged the same amounts of viral RNA, but the SEM virus bound more efficiently to cells stably expressing the viral receptor human angiotensin-converting enzyme II (hACE2) and became more infectious. Using this SEM pseudovirus, we examined the infectivity and antigenic properties of the natural SARS-CoV-2 variants. We showed that some variants have higher infectivity than the original virus and that some render the neutralizing plasma with lower potency. These studies thus revealed possible mechanisms of the dissemination advantage of these variants. Hence, the SEM pseudovirion provides a useful tool to evaluate the viral infectivity and capability of convalescent sera in neutralizing specific SARS-CoV-2 S dominant variants.
MeSH term(s)	Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Antibodies, Viral/immunology ; Antibodies, Viral/metabolism ; COVID-19/blood ; COVID-19/immunology ; COVID-19/virology ; Cell Line ; Coronavirus Envelope Proteins/genetics ; Coronavirus Envelope Proteins/immunology ; Coronavirus Envelope Proteins/metabolism ; Coronavirus Envelope Proteins/ultrastructure ; Cricetinae ; Humans ; Microscopy, Electron, Transmission ; Mutation ; Neutralization Tests ; SARS-CoV-2/genetics ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; Spike Glycoprotein, Coronavirus/immunology ; Spike Glycoprotein, Coronavirus/metabolism ; Viral Matrix Proteins/genetics ; Viral Matrix Proteins/immunology ; Viral Matrix Proteins/metabolism ; Viral Matrix Proteins/ultrastructure ; Virion/genetics ; Virion/immunology ; Virion/metabolism ; Virion/ultrastructure
Chemical Substances	Antibodies, Viral ; Coronavirus Envelope Proteins ; Spike Glycoprotein, Coronavirus ; Viral Matrix Proteins ; envelope protein, SARS-CoV-2 ; membrane protein, SARS-CoV-2 ; spike protein, SARS-CoV-2 ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
Language	English
Publishing date	2021-08-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms22169087
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Article ; Online: Baicalein Induces G 2 /M Cell Cycle Arrest Associated with ROS Generation and CHK2 Activation in Highly Invasive Human Ovarian Cancer Cells

Tzu-Chao Chuang / Wei-Syun Shao / Shih-Chung Hsu / Shou-Lun Lee / Ming-Ching Kao / Vinchi Wang

Molecules, Vol 28, Iss 1039, p

2023 Volume 1039

Abstract: ... growth inhibition is mediated by the cell cycle arrest in the G 2 /M phase. Baicalein-induced G 2 /M ... proteins and G 2 /M phase regulatory molecules. Blockade of CHK2 activation by CHK2 inhibitors ... protects cells from baicalein-mediated G 2 /M cell cycle arrest. All the results suggest that baicalein has ...

Abstract	Ovarian cancer is a lethal gynecological cancer because drug resistance often results in treatment failure. The CHK2, a tumor suppressor, is considered to be an important molecular target in ovarian cancer due to its role in DNA repair. Dysfunctional CHK2 impairs DNA damage-induced checkpoints, reduces apoptosis, and confers resistance to chemotherapeutic drugs and radiation therapy in ovarian cancer cells. This provides a basis for finding new effective agents targeting CHK2 upregulation or activation to treat or prevent the progression of advanced ovarian cancer. Here, the results show that baicalein (5,6,7-trihydroxyflavone) treatment inhibits the growth of highly invasive ovarian cancer cells, and that baicalein-induced growth inhibition is mediated by the cell cycle arrest in the G 2 /M phase. Baicalein-induced G 2 /M phase arrest is associated with an increased reactive oxygen species (ROS) production, DNA damage, and CHK2 upregulation and activation. Thus, baicalein modulates the expression of DNA damage response proteins and G 2 /M phase regulatory molecules. Blockade of CHK2 activation by CHK2 inhibitors protects cells from baicalein-mediated G 2 /M cell cycle arrest. All the results suggest that baicalein has another novel growth inhibitory effect on highly invasive ovarian cancer cells, which is partly related to G 2 /M cell cycle arrest through the ROS-mediated DNA breakage damage and CHK2 activation. Collectively, our findings provide a molecular basis for the potential of baicalein as an adjuvant therapeutic agent in the treatment of metastatic ovarian cancer.
Keywords	baicalein ; CHK2 ; DNA damage response ; flavone ; ovarian cancer ; pro-oxidant ; Organic chemistry ; QD241-441
Subject code	616
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Small Structural Proteins E and M Render the SARS-CoV-2 Pseudovirus More Infectious and Reveal the Phenotype of Natural Viral Variants

Hsin-I Wang / Zih-Shiuan Chuang / Yu-Ting Kao / Yi-Ling Lin / Jian-Jong Liang / Chun-Che Liao / Ching-Len Liao / Michael M. C. Lai / Chia-Yi Yu

International Journal of Molecular Sciences, Vol 22, Iss 9087, p

2021 Volume 9087

Abstract	The SARS-CoV-2 pseudovirus is a commonly used strategy that mimics certain biological functions of the authentic virus by relying on biological legitimacy at the molecular level. Despite the fact that spike (S), envelope (E), and membrane (M) proteins together wrap up the SARS-CoV-2 virion, most of the reported pseudotype viruses consist of only the S protein. Here, we report that the presence of E and M increased the virion infectivity by promoting the S protein priming. The S, E, and M (SEM)-coated pseudovirion is spherical, containing crown-like spikes on the surface. Both S and SEM pseudoviruses packaged the same amounts of viral RNA, but the SEM virus bound more efficiently to cells stably expressing the viral receptor human angiotensin-converting enzyme II (hACE2) and became more infectious. Using this SEM pseudovirus, we examined the infectivity and antigenic properties of the natural SARS-CoV-2 variants. We showed that some variants have higher infectivity than the original virus and that some render the neutralizing plasma with lower potency. These studies thus revealed possible mechanisms of the dissemination advantage of these variants. Hence, the SEM pseudovirion provides a useful tool to evaluate the viral infectivity and capability of convalescent sera in neutralizing specific SARS-CoV-2 S dominant variants.
Keywords	SARS-CoV-2 ; structural protein ; E and M proteins ; pseudovirus ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	612
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Significant geometric variation of the subducted plate beneath the northernmost Cascadia subduction zone and its tectonic implications as revealed by the 2014 M 6.4 earthquake sequence

Hutchinson, Jesse / Kao, Honn / Riedel, Michael / Obana, Koichiro / Wang, Kelin / Kodaira, Shuichi / Takahashi, Tsutomo / Yamamoto, Yojiro

2020

Abstract: Highlights • Hypocenters within the subducted Explorer plate indicate slab deformation. • The oceanic slab is bending downward toward the northwest. • A complex sequence of focal mechanisms also indicates plate deformation. • Decreased seismic activity ... ...

Abstract	Highlights • Hypocenters within the subducted Explorer plate indicate slab deformation. • The oceanic slab is bending downward toward the northwest. • A complex sequence of focal mechanisms also indicates plate deformation. • Decreased seismic activity in the overriding plate indicates decoupling to the NW. • Deformation and decoupling could limit megathrust rupture propagation. Abstract At the northernmost extent of the Cascadia subduction zone, the Explorer plate subducts at approximately 2 cm/yr, less than half the rate of the Juan de Fuca plate to the south. The boundary between these two plates is known as the Nootka fault zone, which is one of the focuses of the Seafloor Earthquake Array Japan-Canada Cascadia Experiment (SeaJade). During this survey, an 6.4 earthquake occurred on 24 April 2014. This event and the subsequent aftershocks (referred to as the Nootka Sequence) reveal an approximately 40-km-long subducted fault within the Explorer Plate to the north of the Nootka fault zone. We infer that the fault is a subducted conjugate fault because of its nearly identical orientation to those seaward of the subduction front within the Nootka fault zone. The depth distribution and focal mechanisms of the aftershocks indicate significant margin-parallel deformation of the subducting plate. The subduction interface at the Nootka Sequence fault has been deflected downward to the northwest from a depth of approximately 15 – 25 km over a distance of 25 km. We propose two possible scenarios that are modified from previously suggested slab-tear model with induced margin-parallel mantle flow to explain the significant deformation of the young, warm subducting Explorer plate. To the northwest of this change in slab geometry, a lack of seismic activity above the plate interface indicates that the Explorer plate has partially decoupled from the overriding North America plate. We conclude that the geometric variation separating the southern Explorer plate from the north, along with decoupling and a possible intraslab ...
Subject code	550
Language	English
Publishing date	2020-12-01
Publisher	Elsevier
Publishing country	de
Document type	Article ; Online
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Article ; Online: Influence of the Metal Center in M N C Catalysts on the CO2 Reduction Reaction on Gas Diffusion Electrodes

Paul, S. / Kao, Y. L. / Ni, L. / Ehnert, R. / Herrmann Geppert, I. / van de Krol, R. / Stark, R.W. / Jaegermann, W. / Kramm, U.I. / Bogdanoff, P.

2021

Abstract: ... and nitrogen doped carbon catalysts in short M N C , where M Mn3 , Fe3 , Co2 , Ni2 , Cu2 , Zn2 , or ... in the aqueous electrolyte. The almost exclusive presence of isolated M N4 centers as catalytic sites was ... operating conditions. Our work further experimentally revealed the high affinity of M N C catalysts to convert CO2 ...

Abstract	In this work, the influences of various transition metal ions as active sites in high purity metal and nitrogen doped carbon catalysts in short M N C , where M Mn3 , Fe3 , Co2 , Ni2 , Cu2 , Zn2 , or Sn4 in the catalyst powders, were systematically investigated for the electrochemical reduction of CO2 in the aqueous electrolyte. The almost exclusive presence of isolated M N4 centers as catalytic sites was determined by X ray photoelectron spectroscopy XPS . The catalysts were electrochemically investigated in a gas diffusion electrode arrangement in bypass mode coupled in line to a mass spectrometer. This allowed for the nearly simultaneous detection of products and current densities in linear sweep voltammetry experiments, from which potential dependent specific production rates and faradaic efficiencies could be derived. Postmortem XPS analyses were performed after various stages of operation on the Cu N C catalyst, which was the only catalyst to produce hydrocarbons CH4 and C2H4 in significant amounts. The data provided insights into the potential induced electronic changes of the Cu N C catalyst occurring under operating conditions. Our work further experimentally revealed the high affinity of M N C catalysts to convert CO2 to industrially relevant carbonaceous raw materials, while effectively suppressing the competing hydrogen evolution reaction. These results led to a better understanding of the role of the active sites, especially the central metal ion, in M N C and could contribute significantly to the improvement of selectivities and activities for the CO2RR in this catalyst class through tailor made optimization strategies
Keywords	electrocatalysis ; CO2 reduction reaction ; M amp ; 8722;N amp ; 8722;C ; 8722;N4 active centers ; electrochemistry coupled to mass spectrometry ; CO formation ; hydrocarbon formation
Subject code	540 ; 660
Language	Undetermined
Publishing date	2021-01-01
Publishing country	de
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Platinum deposited on 2D and 3D mesoporous silica materials for the catalytic oxidation of volatile organic compounds: The oxidation of m-xylene and methanol

Chen, Ching-Shiun / Chen, Tse-Ching / Wu, Hung-Chi / Huang, Pin-Hsuan / Kao, Hsien-Ming

Journal of catalysis. 2021 Oct., v. 402

2021

Abstract: ... compared for the total oxidation of m-xylene and methanol. SBA-15 effectively controls the growth of Pt ... SBA-16 mesopores. Pt particles deposited on SBA-15 provide a stronger ability to dissociate m-xylene ... in both oxidation reactions. Regarding m-xylene oxidation, the Pt particles on SBA-15 induce the breakage of the CC ...

Abstract	Pt particles deposited on 3D cage-type SBA-16 and 2D-hexagonal SBA-15 mesoporous silica are compared for the total oxidation of m-xylene and methanol. SBA-15 effectively controls the growth of Pt particles in hexagonal channels, producing a smaller particle size than the Pt particles in the cage-like SBA-16 mesopores. Pt particles deposited on SBA-15 provide a stronger ability to dissociate m-xylene and methanol molecules than those formed on SBA-16, thus leading to its high catalytic performance in both oxidation reactions. Regarding m-xylene oxidation, the Pt particles on SBA-15 induce the breakage of the CC bond between phenyl and methyl groups to form CO and carbonyl intermediates, thus enhancing catalytic activity. Methanol adsorbed on Pt catalysts undergoes competitive decomposition and dehydrogenation reactions to form CO and carbonyl species, respectively. SBA-15-supported Pt leads to notable CO formation while also exhibiting high activity for methanol oxidation.
Keywords	catalytic activity ; dehydrogenation ; methanol ; oxidation ; particle size ; platinum ; porous media ; silica ; volatile organic compounds ; xylene
Language	English
Dates of publication	2021-10
Size	p. 275-288.
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	1468993-5
ISSN	1090-2694 ; 0021-9517
ISSN (online)	1090-2694
ISSN	0021-9517
DOI	10.1016/j.jcat.2021.08.012
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Bi-functional fusion enzyme EG-M-Xyn displaying endoglucanase and xylanase activities and its utility in improving lignocellulose degradation.

Chen, Chin-Chung / Gao, Guo-Jhan / Kao, Ai-Ling / Tsai, Zheng-Chia

International journal of biological macromolecules

2018 Volume 111, Page(s) 722–729

Abstract: ... enzyme (EG-M-Xyn). Through the expression and purification by ultrafiltration and ... size-exclusion chromatography, the purified EG-M-Xyn had a molecular weight of 75.5 kDa and exhibited the specific activity ...

Abstract	In this study, the gene fusion of endoglucanase (EG, one of cellulases) from Teleogryllus emma and xylanase (Xyn, one of hemicellulases) from Thermomyces lanuginosus was constructed to generate a fusion enzyme (EG-M-Xyn). Through the expression and purification by ultrafiltration and size-exclusion chromatography, the purified EG-M-Xyn had a molecular weight of 75.5 kDa and exhibited the specific activity of CMCase and xylanase as 306.8 U/mg and 1227.3 U/mg, respectively. The K
MeSH term(s)	Animals ; Biofuels ; Cellulase/chemistry ; Cellulase/genetics ; Cellulases/chemistry ; Cellulases/genetics ; Fermentation ; Gene Fusion ; Gryllidae/enzymology ; Gryllidae/genetics ; Hydrolysis ; Lignin/chemistry ; Lignin/genetics ; Spiroplasma/enzymology ; Spiroplasma/genetics ; Substrate Specificity ; Temperature
Chemical Substances	Biofuels ; lignocellulose (11132-73-3) ; Lignin (9005-53-2) ; Cellulases (EC 3.2.1.-) ; Cellulase (EC 3.2.1.4) ; carboxymethylcellulase (EC 3.2.1.4)
Language	English
Publishing date	2018-02-19
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2018.01.080
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