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  1. Article: Disruptive or disabled? An interview with Dr. Alexis Polles, about the Professional Enhancement Program.

    Polles, Alexis

    Nursing economic$

    2004  Volume 22, Issue 4, Page(s) 205–207

    MeSH term(s) Attitude of Health Personnel ; Clinical Competence/standards ; Disability Evaluation ; Humans ; Physician-Nurse Relations ; Professional Staff Committees/standards ; United States ; Workplace
    Language English
    Publishing date 2004-07
    Publishing country United States
    Document type Interview
    ZDB-ID 639341-x
    ISSN 0746-1739
    ISSN 0746-1739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Adaptations to substance use disorder monitoring by physician health programs in response to COVID-19.

    Polles, Alexis / Bundy, Christopher / Jacobs, William / Merlo, Lisa J

    Journal of substance abuse treatment

    2021  Volume 125, Page(s) 108281

    MeSH term(s) COVID-19 ; Humans ; Physicians ; Substance-Related Disorders/therapy ; Telemedicine
    Language English
    Publishing date 2021-01-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605923-5
    ISSN 1873-6483 ; 0740-5472
    ISSN (online) 1873-6483
    ISSN 0740-5472
    DOI 10.1016/j.jsat.2021.108281
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Role of Alcohol Biomarkers in Detecting a Physician's COVID-19-Related Acute Stress Response: A Case Report.

    Polles, Alexis G / Jacobs, William S / Brazle, Chad / Merlo, Lisa J

    Journal of addiction medicine

    2021  Volume 16, Issue 1, Page(s) e62–e65

    Abstract: Objectives: Alcohol biomarkers are used to detect alcohol exposure in clinical and forensic settings. This includes professional health program (PHP) monitoring of healthcare workers in recovery from substance use disorders. Here we present the case of ... ...

    Abstract Objectives: Alcohol biomarkers are used to detect alcohol exposure in clinical and forensic settings. This includes professional health program (PHP) monitoring of healthcare workers in recovery from substance use disorders. Here we present the case of a physician whose positive alcohol biomarker test result was complicated by a traumatic stress response to frontline work during COVID-19.
    Methods: An anesthesiologist under PHP monitoring for substance use disorder and depression was interviewed extensively, urine and blood biomarkers were obtained, and longitudinal structured and semi-structured interviews related to anxiety, depression, posttraumatic stress, and cravings were used to monitor responses to the unanticipated death of a patient who succumbed to COVID-19.
    Results: After an initial positive ethylglucuronide (EtG) and ethylsulfate (EtS) toxicology test result, all subsequent testing was negative. The physician described compulsive sanitizing hands/arms and mask with highly concentrated ethanol-based products. Standardized assessments and clinical interviews provided documentation of a COVID-19-related post-traumatic stress response. He was connected to additional therapeutic support services and monitoring continued.
    Conclusions: Inhalation of ethanol vapors was initially accepted as a possible explanation for the positive EtG/EtS results, though the physician later acknowledged that limited alcohol beverage consumption occurred 6 days prior to the positive test, further complicating its interpretation. Detection of aberrant behavior through ongoing monitoring helps to protect both healthcare workers and the patients they serve.
    MeSH term(s) Alcohol Drinking ; Biomarkers ; COVID-19 ; Ethanol ; Glucuronates ; Humans ; Male ; Physicians ; SARS-CoV-2 ; Substance Abuse Detection ; Sulfuric Acid Esters
    Chemical Substances Biomarkers ; Glucuronates ; Sulfuric Acid Esters ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2021-04-29
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ISSN 1935-3227
    ISSN (online) 1935-3227
    DOI 10.1097/ADM.0000000000000865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: PATHOS: a brief screening application for assessing sexual addiction.

    Carnes, Patrick J / Green, Bradley A / Merlo, Lisa J / Polles, Alexis / Carnes, Stefanie / Gold, Mark S

    Journal of addiction medicine

    2007  Volume 6, Issue 1, Page(s) 29–34

    Abstract: Unlabelled: Sexual addiction is estimated to afflict up to 3% to 6% of the population. However, many clinicians lack clear criteria for detecting potential cases.: Objectives: The present studies were conducted to assess the effectiveness of a brief ... ...

    Abstract Unlabelled: Sexual addiction is estimated to afflict up to 3% to 6% of the population. However, many clinicians lack clear criteria for detecting potential cases.
    Objectives: The present studies were conducted to assess the effectiveness of a brief sexual addiction screening instrument (ie, PATHOS Questionnaire) to correctly classify patients being treated for sex addiction and healthy volunteers.
    Methods: In study 1, a 6-item questionnaire, which utilizes the mnemonic "PATHOS," was examined in regard to sensitivity and specificity using a sample combining patients being treated for sex addiction and healthy volunteers (970 men/80.2% patients; 938 women/63.8% patients). In study 2, a cross-validation sample of 672 men (93% patients) and 241 women (35.3% patients) completed the PATHOS screener.
    Results: Results of receiver operating characteristics analyses in study 1 demonstrated that the PATHOS captured 92.6% of the area under the curve and achieved 88.3% sensitivity and 81.6% specificity for classifying the male sample (n = 963) as patients and healthy subjects using a cutoff score of 3. Similarly, the PATHOS captured 90.2% of the area under the curve and, with a cutoff of 3, achieved 80.9% sensitivity and 87.2% specificity for the female sample (n = 808). In study 2, results of receiver operating characteristics analyses indicated that the PATHOS captured 85.1% of the area under the curve, with sensitivity of 70.7% and specificity of 86.9% for men (cutoff of 3). For women, the PATHOS captured 80.9% of the area under the curve and achieved 69.7% sensitivity and 85.1% specificity with the cutoff of 3.
    Conclusions: These studies provide support for the use of the PATHOS as a screening instrument to detect potential sexual addiction cases in clinical settings.
    MeSH term(s) Adolescent ; Adult ; Aged ; Behavior, Addictive/diagnosis ; Behavior, Addictive/psychology ; Behavior, Addictive/therapy ; Female ; Humans ; Male ; Mass Screening ; Middle Aged ; Psychometrics/statistics & numerical data ; Reference Values ; Reproducibility of Results ; Residential Treatment ; Sexual Behavior ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2007-12-13
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Validation Study
    ISSN 1932-0620
    ISSN 1932-0620
    DOI 10.1097/ADM.0b013e3182251a28
    Database MEDical Literature Analysis and Retrieval System OnLINE

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