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  1. Article ; Online: Direct admission to home hospitalization from the emergency department: feasible, efficient, and necessary.

    Bibiano Guillén, Carlos

    Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias

    2023  Volume 35, Issue 3, Page(s) 163–164

    Title translation Ingreso directo desde urgencias a domicilio: factible, eficiente y necesario.
    MeSH term(s) Humans ; Hospitalization ; Emergency Service, Hospital
    Language English
    Publishing date 2023-06-23
    Publishing country Spain
    Document type Editorial
    ZDB-ID 2127173-2
    ISSN 2386-5857 ; 2386-5857
    ISSN (online) 2386-5857
    ISSN 2386-5857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Acute phase characteristics and long-term complications of pulmonary embolism in COVID-19 compared to non-COVID-19 cohort: a large single-centre study.

    Franco-Moreno, A / Brown-Lavalle, D / Campos-Arenas, M / Rodríguez-Ramírez, N / Muñoz-Roldán, C / Rubio-Aguilera, A I / Muñoz-Rivas, N / de Girón, J Bascuñana-Morejón / Fernández-Vidal, E / Palma-Huerta, E / Estévez-Alonso, S / Rodríguez-Gómez, B / Manzano-Valera, S / Pedrero-Tomé, R / Casado-Suela, M / Bibiano-Guillén, C / Mir-Montero, M / Torres-Macho, J / Bustamante-Fermosel, A

    BMC pulmonary medicine

    2023  Volume 23, Issue 1, Page(s) 25

    Abstract: Background: To compare the severity of pulmonary embolism (PE) and the long-term complications between patients with and without COVID-19, and to investigate whether the tools for risk stratification of death are valid in this population.: Methods: ... ...

    Abstract Background: To compare the severity of pulmonary embolism (PE) and the long-term complications between patients with and without COVID-19, and to investigate whether the tools for risk stratification of death are valid in this population.
    Methods: We retrospectively included hospitalized patients with PE from 1 January 2016 to 31 December 2022. Comparisons for acute episode characteristics, risk stratification of the PE, outcomes, and long-term complications were made between COVID and non-COVID patients.
    Results: We analyzed 116 (27.5%) COVID patients and 305 (72.4%) non-COVID patients. In patients with COVID-19, the traditional risk factors for PE were absent, and the incidence of deep vein thrombosis was lower. COVID patients showed significantly higher lymphocyte count, lactate dehydrogenase, lactic acid, and D-dimer levels. COVID patients had PE of smaller size (12.3% vs. 25.5% main pulmonary artery, 29.8% vs. 37.1% lobar, 44.7% vs. 29.5% segmental and 13.2% vs. 7.9% subsegmental, respectively; p < 0.001), less right ventricular dysfunction (7.7% vs. 17.7%; p = 0.007) and higher sPESI score (1.66 vs. 1.11; p < 0.001). The need for mechanical ventilation was significantly higher in COVID patients (8.6% vs. 1.3%; p < 0.001); However, the in-hospital death was less (5.2% vs. 10.8%; p = 0.074). The incidence of long-term complications was lower in COVID cohort (p < 0.001). PE severity assessed by high sPESI and intermediate and high-risk categories were independently associated with in-hospital mortality in COVID patients.
    Conclusion: The risk of in-hospital mortality and the incidence of long-term complications were lower in COVID-19. The usual tools for risk stratification of PE are valid in COVID patients.
    MeSH term(s) Humans ; Hospital Mortality ; COVID-19/complications ; Retrospective Studies ; Pulmonary Embolism/complications ; Pulmonary Artery ; Risk Assessment
    Language English
    Publishing date 2023-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-023-02323-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of EARLY administration of DEXamethasone in patients with COVID-19 pneumonia without acute hypoxemic respiratory failure and risk of development of acute respiratory distress syndrome (EARLY-DEX COVID-19): study protocol for a randomized controlled trial.

    Franco-Moreno, Anabel / Acedo-Gutiérrez, María Soledad / Martín, Nicolás Labrador-San / Hernández-Blanco, Clara / Rodríguez-Olleros, Celia / Ibáñez-Estéllez, Fátima / Suárez-Simón, Ana / Balado-Rico, Mateo / Romero-Paternina, Ana Rocío / Alonso-Menchén, David / Escolano-Fernández, Belén / Piniella-Ruiz, Esther / Alonso-Monge, Ester / Notario-Leo, Helena / Bibiano-Guillén, Carlos / Peña-Lillo, Gabriela / Antiqueira-Pérez, Armando / Romero-Pareja, Rodolfo / Cabello-Clotet, Noemí /
    Estrada-Pérez, Vicente / Troya-García, Jesús / de Carranza-López, María / Escobar-Rodríguez, Ismael / Vallejo-Maroto, Nacho / Torres-Macho, Juan

    Trials

    2022  Volume 23, Issue 1, Page(s) 784

    Abstract: ... Risk for the development of ARDS is defined as levels of lactate dehydrogenase > 245 U/L, C-reactive ...

    Abstract Background: Corticosteroids are one of the few drugs that have shown a reduction in mortality in coronavirus disease 2019 (COVID-19). In the RECOVERY trial, the use of dexamethasone reduced 28-day mortality compared to standard care in hospitalized patients with suspected or confirmed COVID-19 requiring supplemental oxygen or invasive mechanical ventilation. Evidence has shown that 30% of COVID-19 patients with mild symptoms at presentation will progress to acute respiratory distress syndrome (ARDS), particularly patients in whom laboratory inflammatory biomarkers associated with COVID-19 disease progression are detected. We postulated that dexamethasone treatment in hospitalized patients with COVID-19 pneumonia without additional oxygen requirements and at risk of progressing to severe disease might lead to a decrease in the development of ARDS and thereby reduce death.
    Methods/design: This is a multicenter, randomized, controlled, parallel, open-label trial testing dexamethasone in 252 adult patients with COVID-19 pneumonia who do not require supplementary oxygen on admission but are at risk factors for the development of ARDS. Risk for the development of ARDS is defined as levels of lactate dehydrogenase > 245 U/L, C-reactive protein > 100 mg/L, and lymphocyte count of < 0.80 × 10
    Discussion: If our hypothesis is correct, the results of this study will provide additional insights into the management and progression of this specific subpopulation of patients with COVID-19 pneumonia without additional oxygen requirements and at risk of progressing to severe disease.
    Trial registration: ClinicalTrials.gov NCT04836780. Registered on 8 April 2021 as EARLY-DEX COVID-19.
    MeSH term(s) Adrenal Cortex Hormones/adverse effects ; Adult ; C-Reactive Protein ; COVID-19/complications ; COVID-19/drug therapy ; Dexamethasone/adverse effects ; Humans ; Lactate Dehydrogenases ; Multicenter Studies as Topic ; Oxygen ; Pneumonia/drug therapy ; Randomized Controlled Trials as Topic ; Respiratory Distress Syndrome/epidemiology ; Respiratory Insufficiency/epidemiology
    Chemical Substances Adrenal Cortex Hormones ; Dexamethasone (7S5I7G3JQL) ; C-Reactive Protein (9007-41-4) ; Lactate Dehydrogenases (EC 1.1.-) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2022-09-15
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-022-06722-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Adapted Diving Mask (ADM) device as respiratory support with oxygen output during COVID-19 pandemic.

    Bibiano-Guillen, C / Arias-Arcos, B / Collado-Escudero, C / Mir-Montero, M / Corella-Montoya, F / Torres-Macho, J / Buendía-Garcia, M J / Larrainzar-Garijo, R

    The American journal of emergency medicine

    2020  Volume 39, Page(s) 42–47

    MeSH term(s) Adolescent ; Adult ; COVID-19/complications ; Child ; Diving ; Female ; Humans ; Male ; Masks ; Middle Aged ; Oxygen/administration & dosage ; Printing, Three-Dimensional ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/therapy ; Respiratory Insufficiency/prevention & control ; Respiratory Insufficiency/therapy ; Respiratory Protective Devices ; SARS-CoV-2 ; Young Adult
    Chemical Substances Oxygen (S88TT14065)
    Keywords covid19
    Language English
    Publishing date 2020-10-28
    Publishing country United States
    Document type Evaluation Study ; Journal Article
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2020.10.043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Adapted Diving Mask (ADM) device as respiratory support with oxygen output during COVID-19 pandemic

    Bibiano-Guillen, C / Arias-Arcos, B / Collado-Escudero, C / Mir-Montero, M / Corella-Montoya, F / Torres-Macho, J / Buendía-Garcia, M J / Larrainzar-Garijo, R

    Am. j. emerg. med

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #919746
    Database COVID19

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  6. Article ; Online: Adapted Diving Mask (ADM) device as respiratory support with oxygen output during COVID-19 pandemic

    Bibiano-Guillen, C. / Arias-Arcos, B. / Collado-Escudero, C. / Mir-Montero, M. / Corella-Montoya, F. / Torres-Macho, J. / Buendía-Garcia, M.J. / Larrainzar-Garijo, R.

    The American Journal of Emergency Medicine ; ISSN 0735-6757

    2020  

    Keywords Emergency Medicine ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.ajem.2020.10.043
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Emergency department ultrasound screening for lung injury in patients with COVID-19 a validation study.

    Arnanz González, Irene / García Bógalo, Raúl / Mir Montero, María / Guzmán Domenech, David / Larrainzar Garijo, Ricardo / Bibiano Guillén, Carlos

    Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias

    2021  Volume 33, Issue 5, Page(s) 402–404

    Title translation Validación de la ecografía torácica como prueba de despistaje de lesiones pulmonares en pacientes con COVID-19 en un servicio de urgencias.
    MeSH term(s) COVID-19 ; Emergency Service, Hospital ; Humans ; Lung Injury ; SARS-CoV-2 ; Ultrasonography
    Language English
    Publishing date 2021-09-28
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2127173-2
    ISSN 2386-5857 ; 2386-5857
    ISSN (online) 2386-5857
    ISSN 2386-5857
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  8. Article ; Online: Performance of 3 frailty scales for predicting adverse outcomes at 30 days in older patients discharged from emergency departments.

    Fernández Alonso, Cesáreo / Del Arco Galán, Carmen / Torres Garate, Raquel / Madrigal Valdés, José Fernando / Romero Pareja, Rodolfo / Bibiano Guillén, Carlos / Rodríguez Miranda, Belén / Ruiz Grinspan, Martín S / Gutiérrez Gabriel, Sonia / Del Rey Ubago, Ana / Fuentes Ferrer, Manuel E / Martín-Sánchez, Francisco Javier

    Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias

    2023  Volume 35, Issue 3, Page(s) 196–204

    Abstract: Objectives: To compare the ability of 3 frailty scales (the Clinical Frailty Scale [CFS], the Functional Index - eMergency [FIM], and the Identification of Seniors at Risk [ISAR] scale) to predict adverse outcomes at 30 days in older patients discharged ...

    Title translation Rendimiento de tres escalas de fragilidad para predecir resultados adversos a 30 días en los pacientes mayores dados de alta en los servicios de urgencias.
    Abstract Objectives: To compare the ability of 3 frailty scales (the Clinical Frailty Scale [CFS], the Functional Index - eMergency [FIM], and the Identification of Seniors at Risk [ISAR] scale) to predict adverse outcomes at 30 days in older patients discharged from hospital emergency departments (EDs).
    Material and methods: Secondary analysis of data from the FRAIL-Madrid registry of patients aged 75 years or older who were discharged from Madrid EDs over a period of 3 months in 2018 and 2019. Frailty was defined by a CFS score over 4, a FIM score over 2, or an ISAR score over 3. The outcome variables were revisits to an ED, hospitalization, functional decline, death, and a composite variable of finding any of the previously named variables within 30 days of discharge.
    Results: A total of 619 patients were studied. The mean (SD) age was 84 (7) years, and 59.1% were women. The CFS identified as frail a total of 339 patients (54.8%), the FIM 386 (62.4%), and the ISAR 301 (48.6%). An adverse outcome occurred within 30 days in 226 patients (36.5%): 21.5% revisited, 12.6% were hospitalized, 18.4% experienced functional decline, and 3.6% died. The areas under the receiver operating characteristic curves were as follows: CFS, 0.66 (95% CI, 0.62-0.70; P = .022); FIM, 0.67 (95% CI, 0.62-0.71; P = .021), and ISAR, 0.64 (95% CI, 0.60-0.69; P = .023). Adjusted odds ratios (aOR) showed that frailty was an independent risk factor for presenting any of the named adverse outcomes: aOR for CFS >4, 3.18 (95% CI, 2.02-5.01), P .001; aOR for FIM > 2, 3.49 (95% CI, 2.15-5.66), P .001; and aOR for ISAR >3, 2.46 (95% CI, 1.60-3.79), P .001.
    Conclusion: All 3 scales studied - the CFS, the FIM and the ISAR - are useful for identifying frail older patients at high risk of developing an adverse outcome (death, functional decline, hospitalization, or revisiting the ED) within 30 days after discharge.
    MeSH term(s) Aged ; Humans ; Female ; Male ; Patient Discharge ; Frailty/diagnosis ; Frailty/epidemiology ; Geriatric Assessment ; Risk Assessment ; Emergency Service, Hospital
    Language English
    Publishing date 2023-06-23
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2127173-2
    ISSN 2386-5857 ; 2386-5857
    ISSN (online) 2386-5857
    ISSN 2386-5857
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  9. Article ; Online: Clinical features of patients inappropriately undiagnosed of pulmonary embolism.

    Torres-Macho, Juan / Mancebo-Plaza, Ana B / Crespo-Giménez, Ana / Sanz de Barros, M Rosa / Bibiano-Guillén, Carlos / Fallos-Martí, Raúl / Calderón-Parra, Jorge / de Miguel-Yanes, José M

    The American journal of emergency medicine

    2013  Volume 31, Issue 12, Page(s) 1646–1650

    Abstract: Purposes: The objective of this study was to identify clinical factors associated with delayed diagnosis of acute pulmonary embolism (PE) in the emergency department (ED).: Basic procedures: A retrospective observational study was performed at three ... ...

    Abstract Purposes: The objective of this study was to identify clinical factors associated with delayed diagnosis of acute pulmonary embolism (PE) in the emergency department (ED).
    Basic procedures: A retrospective observational study was performed at three University affiliated Hospitals; 436 consecutive patients who presented to the ED with an acute PE confirmed by chest computed tomography from 2008 to 2011 were included. Patients were divided into 3 groups: group 1, PE was diagnosed while the patient was still in the ED; group 2, PE was diagnosed during hospitalization; group 3, patients who were sent home with a wrong alternative diagnosis and returned to the ED and were diagnosed of PE.
    Main findings: One hundred forty-six patients (33.5%) had a delayed diagnosis of PE--21.5% belong to group 2 and 11.9% to Group 3. Chronic coexisting medical conditions like asthma or chronic obstructive pulmonary disease were independent predictors of a delayed diagnosis in patients who were admitted to hospital whereas non-specific and less severe symptoms like the presence of pleuro-mechanic thoracic pain, fever, hemoptysis, or the presence of a pulmonary infiltrate in chest x-ray were independent predictors of a delayed diagnosis in patients who were sent home.
    Principal conclusions: Delay in diagnosis of acute PE is frequent despite current diagnostic strategies. Patients are sent home or admitted to hospital with a wrong diagnosis depending on clinical presentation or coexisting medical conditions.
    MeSH term(s) Age Distribution ; Aged ; Aged, 80 and over ; Chest Pain/etiology ; Comorbidity ; Coronary Artery Disease/epidemiology ; Cough/etiology ; Delayed Diagnosis/statistics & numerical data ; Diabetes Mellitus/epidemiology ; Diagnostic Errors/statistics & numerical data ; Emergency Service, Hospital ; Female ; Heart Failure/epidemiology ; Hemoptysis/etiology ; Humans ; Male ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Pulmonary Embolism/complications ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/epidemiology ; Retrospective Studies ; Risk Factors ; Smoking/epidemiology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2013-12
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2013.08.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Developing modular training components to support home hospital digital solutions: Results of a Delphi panel.

    Abril-Jiménez, Patricia / Merino-Barbancho, Beatriz / Vera-Muñoz, Cecilia / Mallo de la Calle, Irene / Villanueva-Mascato, Samanta / Bibiano Guillen, Carlos / Pinuaga Orrasco, Raquel / Mallaina-García, Raúl / Teresa Arredondo Waldmeyer, María / Fico, Giuseppe

    International journal of medical informatics

    2021  Volume 158, Page(s) 104655

    Abstract: Background: Home hospitalization (HH) has demonstrated to be a cost-effective alternative with respect ti traditional hospitalization. Digital technologies, such as remote monitoring, have the potential to contribute to its expansion. Tailored ... ...

    Abstract Background: Home hospitalization (HH) has demonstrated to be a cost-effective alternative with respect ti traditional hospitalization. Digital technologies, such as remote monitoring, have the potential to contribute to its expansion. Tailored educational content is a need to ensure patient safety during the whole admission.
    Purpose: The objective of this study was to systematically obtain consensus on patients with HH using training in the digital monitoring system. The goal of this work was to develop an adaptable modular and personalized training program for patients to support quality and safety care for HH.
    Methods: The methodological approach for developing the proposed training content followed a modified Delphi technique with a multidisciplinary group of experts with significant knowledge of health informatics and HH protocols in Spain. The study comprised two rounds of training material description and gathering were completed. In Round 1, the experts received 58 predefined items obtained from the literature review and protocol selection. 20 items were rejected for different reasons and 25 new items were proposed. In Round 2, the experts selected the final items to build on the training content for every type of user and illness.
    Results: A total of 21 experts completed rounds 1 and 2. The consensus was reached at the end of Round 2 with the inclusion of 53 items to build the training material. This included 17 treatment procedures, 4 diagnosis procedures, 22 additional support content, and 10 content features that describe how to build and deliver customized training content.
    Conclusions: Participants agreed on the type of content, its structure, and delivery methods to build modular training materials that support patients when they are hospitalized at home with the help of digital monitoring tools. This information can be used to create HH training programs that support new HH protocols and provide a standard for evaluating the quality of existing educational materials and programs.
    Language English
    Publishing date 2021-12-03
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 1466296-6
    ISSN 1872-8243 ; 1386-5056
    ISSN (online) 1872-8243
    ISSN 1386-5056
    DOI 10.1016/j.ijmedinf.2021.104655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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