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Article: R&D investments as prebargaining strategies

Pauwels, Wilfried / Kort, Peter M / Vanhaecht, Eve

International game theory review Vol. 16, No. 3 , p. 1-36

2014 Volume 16, Issue 3, Page(s) 1–36

Author's details	Wilfried Pauwels; Peter M. Kort; Eve Vanhaecht
Keywords	Nash bargaining ; R&D investments ; product differentiation ; cost asymmetry
Language	English
Size	graph. Darst.
Publisher	World Scientific
Publishing place	[River Edge], NJ [u.a.]
Document type	Article
ZDB-ID	1500913-0
ISSN	0219-1989
Database	ECONomics Information System

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Article ; Online: A new formula for converting dose-area product to effective dose in dental cone-beam computed tomography.

Pauwels, Ruben

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

2023 Volume 112, Page(s) 102639

Abstract: Purpose: The purpose of this study was to determine a dedicated conversion formula between dose-area product (DAP) and effective dose (E) for dental CBCT, which incorporates X-ray beam energy as well as geometric factors.: Methods: CBCT exposures of ... ...

Abstract	Purpose: The purpose of this study was to determine a dedicated conversion formula between dose-area product (DAP) and effective dose (E) for dental CBCT, which incorporates X-ray beam energy as well as geometric factors. Methods: CBCT exposures of an adult phantom were simulated using PCXMC 2.0 (STUK, Finland). Fifty-seven fields of view (FOV) were included, ranging from Ø4x4cm to Ø21x19cm. Six tube voltages (70 kV to 120 kV), eight combinations of Al (2.5 to 10 mm) and Cu (0 to 0.5 mm) filtration, and four source-isocentre distances (35 to 65 cm) were used, resulting in 10 896 simulated scan protocols. In addition, 10 944 random combinations of scan parameters within the aforementioned ranges were simulated, resulting in 21 840 scan protocols that were used for fitting a formula using multiple linear regression with 8 independent variables. Finally, 2304 random scan protocols were simulated as validation data to evaluate the formula's generalizability. Results: E/DAP ranged between 0.031 µSv/mGy.cm Conclusion: The new formulas allow for a straightforward, yet accurate, estimation of the effective dose for dental CBCT based on DAP. Further fine-tuning of the model could be achieved by incorporating, for example, bowtie filtration and off-axis beam geometries.
MeSH term(s)	Radiation Dosage ; Cone-Beam Computed Tomography/methods ; Finland ; Phantoms, Imaging
Language	English
Publishing date	2023-07-11
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1122650-x
ISSN	1724-191X ; 1120-1797
ISSN (online)	1724-191X
ISSN	1120-1797
DOI	10.1016/j.ejmp.2023.102639
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Article ; Online: Corrigendum to "A new formula for converting dose-area product to effective dose in dental cone-beam computed tomography" [Phys. Med. 112 (2023) 102639].

Pauwels, Ruben

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

2023 Volume 114, Page(s) 102680

Language	English
Publishing date	2023-09-13
Publishing country	Italy
Document type	Published Erratum
ZDB-ID	1122650-x
ISSN	1724-191X ; 1120-1797
ISSN (online)	1724-191X
ISSN	1120-1797
DOI	10.1016/j.ejmp.2023.102680
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Article: Airway IgG counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on Fc gamma R and IFN-gamma.

Sehra, Sarita / Pynaert, Gwenda / Tournoy, Kurt / Haegeman, Anuschka / Matthys, Patrick / Tagawa, Yohichi / Pauwels, Romain / Grooten, Johan

Journal of immunology (Baltimore, Md. : 1950)

2003 Volume 171, Issue 4, Page(s) 2080–2089

Abstract: Besides IgE, the Ab isotype that gives rise to sensitization and allergic asthma, the immune response to common inhalant allergens also includes IgG. Increased serum titers of allergen-specific IgG, induced spontaneously or by allergen vaccination, have ... ...

Abstract	Besides IgE, the Ab isotype that gives rise to sensitization and allergic asthma, the immune response to common inhalant allergens also includes IgG. Increased serum titers of allergen-specific IgG, induced spontaneously or by allergen vaccination, have been implicated in protection against asthma. To verify the interference of topical IgG with the allergen-triggered eosinophilic airway inflammation that underlies asthma, sensitized mice were treated by intranasal instillation of specific IgG, followed by allergen challenge. This treatment strongly reduced eosinophilic inflammation and goblet cell metaplasia, and increased Th1 reactivity and IFN-gamma levels in bronchoalveolar lavage fluid. In contrast, inflammatory responses were unaffected in IFN-gamma-deficient mice or when applying F(ab')(2). Although dependent on specific allergen-IgG interaction, inflammation triggered by bystander allergens was similarly repressed. Perseverance of inflammation repression, apparent after secondary allergen challenge, and increased allergen capture by alveolar macrophages further characterized the consequences of topical IgG application. These results assign a novel protective function to anti-allergen IgG namely at the local level interference with the inflammatory cascade, resulting in repression of allergic inflammation through an FcgammaR- and IFN-gamma-dependent mechanism. Furthermore, these results provide a basis for topical immunotherapy of asthma by direct delivery of anti-allergen IgG to the airways.
MeSH term(s)	Administration, Intranasal ; Allergens/administration & dosage ; Allergens/immunology ; Allergens/metabolism ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Bronchoalveolar Lavage Fluid/chemistry ; Bronchoalveolar Lavage Fluid/cytology ; Bronchoalveolar Lavage Fluid/immunology ; Bystander Effect/immunology ; Cytokines/biosynthesis ; Epitopes/administration & dosage ; Epitopes/immunology ; Female ; Immunoglobulin Fc Fragments/chemistry ; Immunoglobulin Fc Fragments/physiology ; Immunoglobulin G/administration & dosage ; Immunoglobulin G/chemistry ; Immunoglobulin G/physiology ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation/prevention & control ; Injections, Intraperitoneal ; Interferon-gamma/physiology ; Lung/immunology ; Lung/metabolism ; Lung/pathology ; Mice ; Mice, Inbred BALB C ; Ovalbumin/administration & dosage ; Ovalbumin/antagonists & inhibitors ; Ovalbumin/immunology ; Ovalbumin/metabolism ; Protein Structure, Tertiary/physiology ; Receptors, IgG/physiology ; Th1 Cells/immunology ; Th1 Cells/metabolism ; Th2 Cells/immunology ; Th2 Cells/metabolism
Chemical Substances	Allergens ; Anti-Inflammatory Agents, Non-Steroidal ; Cytokines ; Epitopes ; Immunoglobulin Fc Fragments ; Immunoglobulin G ; Receptors, IgG ; Interferon-gamma (82115-62-6) ; Ovalbumin (9006-59-1)
Language	English
Publishing date	2003-07-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3056-9
ISSN	1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
ISSN (online)	1550-6606
ISSN	0022-1767 ; 1048-3233 ; 1047-7381
DOI	10.4049/jimmunol.171.4.2080
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Article ; Online: A brief introduction to concepts and applications of artificial intelligence in dental imaging.

Pauwels, Ruben

Oral radiology

2020 Volume 37, Issue 1, Page(s) 153–160

Abstract: This report aims to summarize the fundamental concepts of Artificial Intelligence (AI), and to provide a non-exhaustive overview of AI applications in dental imaging, comprising diagnostics, forensics, image processing and image reconstruction. AI has ... ...

Abstract	This report aims to summarize the fundamental concepts of Artificial Intelligence (AI), and to provide a non-exhaustive overview of AI applications in dental imaging, comprising diagnostics, forensics, image processing and image reconstruction. AI has arguably become the hottest topic in radiology in recent years owing to the increased computational power available to researchers, the continuing collection of digital data, as well as the development of highly efficient algorithms for machine learning and deep learning. It is now feasible to develop highly robust AI applications that make use of the vast amount of data available to us, and that keep learning and improving over time.
MeSH term(s)	Algorithms ; Artificial Intelligence ; Image Processing, Computer-Assisted ; Machine Learning ; Radiology
Language	English
Publishing date	2020-08-16
Publishing country	Japan
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639456-5
ISSN	1613-9674 ; 0911-6028
ISSN (online)	1613-9674
ISSN	0911-6028
DOI	10.1007/s11282-020-00468-5
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Article ; Online: How Reliable Are Impact Factors for Ranking Water Resources Journals? An Analysis of the 70,878 Citation Records of the 2002 and 2021 Top 10 Journals for the Last Two Decades

Pauwels, Valentijn R. N.

Water Resources Research. 2023 Mar., v. 59, no. 3 p.e2022WR033352-

2023

Abstract: Despite regularly being criticized, the Impact Factor (IF) remains a widely used journal analysis metric. In the Water Resources category of the Web of Science, a thorough investigation of the reliability of this metric is lacking. This study analyzed ... ...

Abstract	Despite regularly being criticized, the Impact Factor (IF) remains a widely used journal analysis metric. In the Water Resources category of the Web of Science, a thorough investigation of the reliability of this metric is lacking. This study analyzed the citation records of the top 10 journals from 2002 through 2021 for the last two decades. Important to note, there are inconsistencies in the Web of Science database. Contradictory to many fields, few papers are uncited. However, the Simpson paradox applies. More specifically, on the one hand, the correlation between citations to papers 7 years post publication and 1 or 2 years post publication (which determine the IF) has increased, which supports this metric. On the other hand, many of the most highly cited papers at the time of the IF calculation are lowly cited 5 years afterward. Additionally, most currently very highly cited papers were relatively uncited when they were used in the IF calculation. This raises doubt about the usefulness of this metric. For a limited number of journals, papers from individual nations strongly influence the IF. Also, for a few journals, the IFs are strongly influenced by review papers, but leaving these out of the IF does change the top 3 and 10 of the rankings. The general conclusion is that IFs do contain some valuable information about the journals' citation impact, but that using them to rank journals is questionable practice.
Keywords	databases ; research ; water
Language	English
Dates of publication	2023-03
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	5564-5
ISSN	1944-7973 ; 0043-1397
ISSN (online)	1944-7973
ISSN	0043-1397
DOI	10.1029/2022WR033352
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Spontaneous coronary artery dissection of two coronary arteries in a young female patient: a case report.

Lanckneus, Marie / Truyens, Marie / Pauwels, Ruben

Acta cardiologica

2024 Volume 79, Issue 2, Page(s) 254–257

MeSH term(s)	Humans ; Female ; Coronary Vessels/diagnostic imaging ; Coronary Vessels/surgery ; Vascular Diseases/diagnosis ; Vascular Diseases/etiology ; Vascular Diseases/congenital ; Coronary Vessel Anomalies/diagnostic imaging ; Coronary Vessel Anomalies/complications ; Coronary Angiography/adverse effects
Language	English
Publishing date	2024-03-05
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	390197-x
ISSN	1784-973X ; 0001-5385
ISSN (online)	1784-973X
ISSN	0001-5385
DOI	10.1080/00015385.2024.2323873
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Article ; Online: Moral Foundations Questionnaire and Moral Foundations Sacredness Scale: Assessing the Factorial Structure of the Dutch Translations.

De Buck, Ann / Pauwels, Lieven J R

Psychologica Belgica

2023 Volume 63, Issue 1, Page(s) 92–104

Abstract: The Moral Foundations Questionnaire (MFQ) and the Moral Foundations Sacredness Scale (MFSS) have been proposed to advance conceptualizations of morality. This study assesses the factor structure of the Dutch translations of the short version of the MFQ ( ... ...

Abstract	The Moral Foundations Questionnaire (MFQ) and the Moral Foundations Sacredness Scale (MFSS) have been proposed to advance conceptualizations of morality. This study assesses the factor structure of the Dutch translations of the short version of the MFQ (20 items) and the full MFSS. The five-factor model posited by Moral Foundations Theory (MFT) is compared against alternative models of morality. Correlational analyses are performed between the best-fitting models. A multi-group confirmatory factor analysis of the optimal model is tested across gender. Data are taken from an online survey of a student sample (
Language	English
Publishing date	2023-07-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2634810-X
ISSN	2054-670X ; 2054-670X
ISSN (online)	2054-670X
ISSN	2054-670X
DOI	10.5334/pb.1188
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: Strategic R&D and patent behaviour in some EU-countries

Plasmans, Joseph E. J / Pauwels, Wilfried / Thewys, Theo

(Research paper / University of Antwerp ; 99,42)

1999

Author's details	Joseph E. J. Plasmans; Wilfried Pauwels; Theo Thewys
Series title	Research paper / University of Antwerp ; 99,42
Keywords	Industrieforschung ; Patent ; Innovation ; Spillover-Effekt ; Spieltheorie ; EU-Staaten
Language	English
Size	23 Bl, graph. Darst
Publishing place	Antwerp
Document type	Book
Database	ECONomics Information System

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Article ; Online: Accuracy of Intra-Oral Radiography and Cone Beam Computed Tomography in the Diagnosis of Buccal Bone Loss.

Christiaens, Véronique / Pauwels, Ruben / Mowafey, Bassant / Jacobs, Reinhilde

Journal of imaging

2023 Volume 9, Issue 8

Abstract: Background: The use of cone beam computed tomography (CBCT) in dentistry started in the maxillofacial field, where it was used for complex and comprehensive treatment planning. Due to the use of reduced radiation dose compared to a computed tomography ( ... ...

Abstract	Background: The use of cone beam computed tomography (CBCT) in dentistry started in the maxillofacial field, where it was used for complex and comprehensive treatment planning. Due to the use of reduced radiation dose compared to a computed tomography (CT) scan, CBCT has become a frequently used diagnostic tool in dental practice. However, published data on the accuracy of CBCT in the diagnosis of buccal bone level is lacking. The aim of this study was to compare the accuracy of intra-oral radiography (IOR) and CBCT in the diagnosis of the extent of buccal bone loss. Methods: A dry skull was used to create a buccal bone defect at the most coronal level of a first premolar; the defect was enlarged apically in steps of 1 mm. After each step, IOR and CBCT were taken. Based on the CBCT data, two observers jointly selected three axial slices at different levels of the buccal bone, as well as one transverse slice. Six dentists participated in the radiographic observations. First, all observers received the 10 intra-oral radiographs, and each observer was asked to rank the intra-oral radiographs on the extent of the buccal bone defect. Afterwards, the procedure was repeated with the CBCT scans based on a combination of axial and transverse information. For the second part of the study, each observer was asked to evaluate the axial and transverse CBCT slices on the presence or absence of a buccal bone defect. Results: The percentage of buccal bone defect progression rankings that were within 1 of the true rank was 32% for IOR and 42% for CBCT. On average, kappa values increased by 0.384 for CBCT compared to intra-oral radiography. The overall sensitivity and specificity of CBCT in the diagnosis of the presence or absence of a buccal bone defect was 0.89 and 0.85, respectively. The average area under the curve (AUC) of the receiver operating curve (ROC) was 0.892 for all observers. Conclusion: When CBCT images are available for justified indications, other than bone level assessment, such 3D images are more accurate and thus preferred to 2D images to assess periodontal buccal bone. For other clinical applications, intra-oral radiography remains the standard method for radiographic evaluation.
Language	English
Publishing date	2023-08-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2824270-1
ISSN	2313-433X ; 2313-433X
ISSN (online)	2313-433X
ISSN	2313-433X
DOI	10.3390/jimaging9080164
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