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Book ; Online ; Thesis: Effect of Synthesis Conditions on the Properties of Lead Iron Niobate Ceramics and Thin Films: Possible Candidate for Photovoltaic Devices?

Bartek, Nicole [Verfasser] / Lupascu, Doru C. [Akademischer Betreuer]

2023

Author's details	Nicole Bartek ; Betreuer: Doru C. Lupascu
Keywords	Naturwissenschaften ; Science
Subject code	sg500
Language	English
Publisher	Duisburg ; Universität Duisburg-Essen
Publishing place	Essen
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

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Article ; Online: Addressing the Clinical Impact of COVID-19 on Pediatric Mental Health.

Bartek, Nicole / Peck, Jessica L / Garzon, Dawn / VanCleve, Susan

Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners

2021 Volume 35, Issue 4, Page(s) 377–386

Abstract: The COVID-19 pandemic impacts daily lives of families globally. Sequelae are not limited to physical consequences of medical complications but extend into social, emotional, spiritual, and psychological health. Interventions including mask-wearing and ... ...

Abstract	The COVID-19 pandemic impacts daily lives of families globally. Sequelae are not limited to physical consequences of medical complications but extend into social, emotional, spiritual, and psychological health. Interventions including mask-wearing and physical distancing are intended to prevent viral spread, but have unintended negative effects on mental health and child development. Although it is too early to know the full impact, practicing pediatric clinicians are well-positioned to help young people recover and thrive despite challenges presented. This article will review the impact of COVID-19 on child mental health and give practical interventions to foster resilience in youth and their families.
MeSH term(s)	COVID-19/psychology ; Child ; Child Development ; Family Health ; Female ; Humans ; Male ; Mental Health ; Pandemics ; Resilience, Psychological ; SARS-CoV-2
Language	English
Publishing date	2021-03-24
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1036356-7
ISSN	1532-656X ; 0891-5245
ISSN (online)	1532-656X
ISSN	0891-5245
DOI	10.1016/j.pedhc.2021.03.006
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Article: Reducing psychiatric illness in the perinatal period: A review and commentary.

Rohr, Jessica / Vahidy, Farhaan S / Bartek, Nicole / Bourassa, Katelynn A / Nanavaty, Namrata R / Antosh, Danielle D / Harms, Konrad P / Stanley, Jennifer L / Madan, Alok

World journal of psychiatry

2023 Volume 13, Issue 4, Page(s) 149–160

Abstract: This brief overview highlights the global crisis of perinatal psychiatric illness (PPI). PPI is a major contributor to many adverse pregnancy, childbirth, and childhood development outcomes. It contributes to billions of dollars in spending worldwide ... ...

Abstract	This brief overview highlights the global crisis of perinatal psychiatric illness (PPI). PPI is a major contributor to many adverse pregnancy, childbirth, and childhood development outcomes. It contributes to billions of dollars in spending worldwide each year and has a significant impact on the individual, their family, and their community. It is also highly preventable. Current recommendations for intervention and management of PPI are limited and vary considerably from country to country. Furthermore, there are several significant challenges asso-ciated with implementation of these recommendations. These challenges are magnified in number and consequence among women of color and/or minority populations, who experience persistent and negative health disparities during pregnancy and the postpartum period. This paper aims to provide a broad overview of the current state of recommendations and implementation challenges for PPI and layout a framework for overcoming these challenges. An equity-informed model of care that provides universal intervention for pregnant women may be one solution to address the preventable consequences of PPI on child and maternal health. Uniquely, this model emphasizes the importance of managing and eliminating known barriers to traditional health care models. Culturally and contextually specific challenges must be overcome to fully realize the impact of improved management of PPI.
Language	English
Publishing date	2023-04-19
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2220-3206
ISSN	2220-3206
DOI	10.5498/wjp.v13.i4.149
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Band Gap of Pb(Fe

Bartek, Nicole / Shvartsman, Vladimir V / Bouyanfif, Houssny / Schmitz, Alexander / Bacher, Gerd / Olthof, Selina / Sirotinskaya, Svetlana / Benson, Niels / Lupascu, Doru C

Materials (Basel, Switzerland)

2021 Volume 14, Issue 22

Abstract: Ferroelectric materials have gained high interest for photovoltaic applications due to their open-circuit voltage not being limited to the band gap of the material. In the past, different lead-based ferroelectric perovskite thin films such as Pb(Zr,Ti) ... ...

Abstract	Ferroelectric materials have gained high interest for photovoltaic applications due to their open-circuit voltage not being limited to the band gap of the material. In the past, different lead-based ferroelectric perovskite thin films such as Pb(Zr,Ti)O
Language	English
Publishing date	2021-11-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma14226841
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Article ; Online: A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.

Magkouta, Sophia / Veroutis, Dimitris / Pousias, Athanasios / Papaspyropoulos, Angelos / Pippa, Natassa / Lougiakis, Nikolaos / Kambas, Konstantinos / Lagopati, Nefeli / Polyzou, Aikaterini / Georgiou, Maria / Chountoulesi, Maria / Pispas, Stergios / Foutadakis, Spyros / Pouli, Nicole / Marakos, Panagiotis / Kotsinas, Athanassios / Verginis, Panayotis / Valakos, Dimitrios / Mizi, Athanasia /

Papantonis, Argyris / Vatsellas, Giannis / Galanos, Panagiotis / Bartek, Jiri / Petty, Russell / Serrano, Manuel / Thanos, Dimitris / Roussos, Charis / Demaria, Marco / Evangelou, Konstantinos / Gorgoulis, Vassilis G

Molecular cell

2023 Volume 83, Issue 19, Page(s) 3558–3573.e7

Abstract: Cellular senescence is a stress-response mechanism implicated in various physiological processes, diseases, and aging. Current detection approaches have partially addressed the issue of senescent cell identification in clinical specimens. Effective ... ...

Abstract	Cellular senescence is a stress-response mechanism implicated in various physiological processes, diseases, and aging. Current detection approaches have partially addressed the issue of senescent cell identification in clinical specimens. Effective methodologies enabling precise isolation or live tracking of senescent cells are still lacking. In-depth analysis of truly senescent cells is, therefore, an extremely challenging task. We report (1) the synthesis and validation of a fluorophore-conjugated, Sudan Black-B analog (GLF16), suitable for in vivo and in vitro analysis of senescence by fluorescence microscopy and flow cytometry and (2) the development and application of a GLF16-carrying micelle vector facilitating GLF16 uptake by living senescent cells in vivo and in vitro. The compound and the applied methodology render isolation of senescent cells an easy, rapid, and precise process. Straightforward nanocarrier-mediated GLF16 delivery in live senescent cells comprises a unique tool for characterization of senescence at an unprecedented depth.
MeSH term(s)	Indicators and Reagents ; Cellular Senescence ; Flow Cytometry
Chemical Substances	Indicators and Reagents
Language	English
Publishing date	2023-10-04
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1415236-8
ISSN	1097-4164 ; 1097-2765
ISSN (online)	1097-4164
ISSN	1097-2765
DOI	10.1016/j.molcel.2023.09.006
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Article ; Online: Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses.

Tas, Jeroen M J / Koo, Ja-Hyun / Lin, Ying-Cing / Xie, Zhenfei / Steichen, Jon M / Jackson, Abigail M / Hauser, Blake M / Wang, Xuesong / Cottrell, Christopher A / Torres, Jonathan L / Warner, John E / Kirsch, Kathrin H / Weldon, Stephanie R / Groschel, Bettina / Nogal, Bartek / Ozorowski, Gabriel / Bangaru, Sandhya / Phelps, Nicole / Adachi, Yumiko /

Eskandarzadeh, Saman / Kubitz, Michael / Burton, Dennis R / Lingwood, Daniel / Schmidt, Aaron G / Nair, Usha / Ward, Andrew B / Schief, William R / Batista, Facundo D

Immunity

2022 Volume 55, Issue 10, Page(s) 1856–1871.e6

Abstract: Vaccines generate high-affinity antibodies by recruiting antigen-specific B cells to germinal centers (GCs), but the mechanisms governing the recruitment to GCs on secondary challenges remain unclear. Here, using preclinical SARS-CoV and HIV mouse models, ...

Abstract	Vaccines generate high-affinity antibodies by recruiting antigen-specific B cells to germinal centers (GCs), but the mechanisms governing the recruitment to GCs on secondary challenges remain unclear. Here, using preclinical SARS-CoV and HIV mouse models, we demonstrated that the antibodies elicited during primary humoral responses shaped the naive B cell recruitment to GCs during secondary exposures. The antibodies from primary responses could either enhance or, conversely, restrict the GC participation of naive B cells: broad-binding, low-affinity, and low-titer antibodies enhanced recruitment, whereas, by contrast, the high titers of high-affinity, mono-epitope-specific antibodies attenuated cognate naive B cell recruitment. Thus, the directionality and intensity of that effect was determined by antibody concentration, affinity, and epitope specificity. Circulating antibodies can, therefore, be important determinants of antigen immunogenicity. Future vaccines may need to overcome-or could, alternatively, leverage-the effects of circulating primary antibodies on subsequent naive B cell recruitment.
MeSH term(s)	Animals ; Antibodies, Neutralizing ; Antibodies, Viral ; Antigens ; B-Lymphocytes ; Epitopes ; Germinal Center ; Immunity, Humoral ; Mice
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral ; Antigens ; Epitopes
Language	English
Publishing date	2022-08-04
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1217235-2
ISSN	1097-4180 ; 1074-7613
ISSN (online)	1097-4180
ISSN	1074-7613
DOI	10.1016/j.immuni.2022.07.020
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Zs.A 4227: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Robust, universal biomarker assay to detect senescent cells in biological specimens.

Evangelou, Konstantinos / Lougiakis, Nikolaos / Rizou, Sophia V / Kotsinas, Athanassios / Kletsas, Dimitris / Muñoz-Espín, Daniel / Kastrinakis, Nikolaos G / Pouli, Nicole / Marakos, Panagiotis / Townsend, Paul / Serrano, Manuel / Bartek, Jiri / Gorgoulis, Vassilis G

Aging cell

2016 Volume 16, Issue 1, Page(s) 192–197

Abstract: Cellular senescence contributes to organismal development, aging, and diverse pathologies, yet available assays to detect senescent cells remain unsatisfactory. Here, we designed and synthesized a lipophilic, biotin-linked Sudan Black B (SBB) analogue ... ...

Abstract	Cellular senescence contributes to organismal development, aging, and diverse pathologies, yet available assays to detect senescent cells remain unsatisfactory. Here, we designed and synthesized a lipophilic, biotin-linked Sudan Black B (SBB) analogue suitable for sensitive and specific, antibody-enhanced detection of lipofuscin-containing senescent cells in any biological material. This new hybrid histo-/immunochemical method is easy to perform, reliable, and universally applicable to assess senescence in biomedicine, from cancer research to gerontology.
MeSH term(s)	Animals ; Biological Assay/methods ; Biomarkers/analysis ; Biotin/metabolism ; Cell Line, Tumor ; Cellular Senescence ; Humans ; Mice
Chemical Substances	Biomarkers ; Biotin (6SO6U10H04)
Language	English
Publishing date	2016-11-17
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2113083-8
ISSN	1474-9726 ; 1474-9718
ISSN (online)	1474-9726
ISSN	1474-9718
DOI	10.1111/acel.12545
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Article ; Online: Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity.

Strauss, Robert / Li, Zong-Yi / Liu, Ying / Beyer, Ines / Persson, Jonas / Sova, Pavel / Möller, Thomas / Pesonen, Sari / Hemminki, Akseli / Hamerlik, Petra / Drescher, Charles / Urban, Nicole / Bartek, Jiri / Lieber, André

PloS one

2011 Volume 6, Issue 1, Page(s) e16186

Abstract: In our studies of ovarian cancer cells we have identified subpopulations of cells that are in a transitory E/M hybrid stage, i.e. cells that simultaneously express epithelial and mesenchymal markers. E/M cells are not homogenous but, in vitro and in vivo, ...

Abstract	In our studies of ovarian cancer cells we have identified subpopulations of cells that are in a transitory E/M hybrid stage, i.e. cells that simultaneously express epithelial and mesenchymal markers. E/M cells are not homogenous but, in vitro and in vivo, contain subsets that can be distinguished based on a number of phenotypic features, including the subcellular localization of E-cadherin, and the expression levels of Tie2, CD133, and CD44. A cellular subset (E/M-MP) (membrane E-cadherin(low)/cytoplasmic E-cadherin(high)/CD133(high), CD44(high), Tie2(low)) is highly enriched for tumor-forming cells and displays features which are generally associated with cancer stem cells. Our data suggest that E/M-MP cells are able to differentiate into different lineages under certain conditions, and have the capacity for self-renewal, i.e. to maintain a subset of undifferentiated E/M-MP cells during differentiation. Trans-differentiation of E/M-MP cells into mesenchymal or epithelial cells is associated with a loss of stem cell markers and tumorigenicity. In vivo xenograft tumor growth is driven by E/M-MP cells, which give rise to epithelial ovarian cancer cells. In contrast, in vitro, we found that E/M-MP cells differentiate into mesenchymal cells, in a process that involves pathways associated with an epithelial-to-mesenchymal transition. We also detected phenotypic plasticity that was dependent on external factors such as stress created by starvation or contact with either epithelial or mesenchymal cells in co-cultures. Our study provides a better understanding of the phenotypic complexity of ovarian cancer and has implications for ovarian cancer therapy.
MeSH term(s)	Biomarkers, Tumor/analysis ; Carcinoma, Ovarian Epithelial ; Cell Transdifferentiation ; Epithelial Cells/pathology ; Epithelial-Mesenchymal Transition ; Female ; Humans ; Mesenchymal Stem Cells/pathology ; Neoplasms, Glandular and Epithelial/pathology ; Neoplastic Stem Cells/pathology ; Ovarian Neoplasms/pathology ; Phenotype
Chemical Substances	Biomarkers, Tumor
Language	English
Publishing date	2011-01-14
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0016186
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Correction

Robert Strauss / Zong-Yi Li / Ying Liu / Ines Beyer / Jonas Persson / Pavel Sova / Thomas Möller / Sari Pesonen / Akseli Hemminki / Petra Hamerlik / Charles Drescher / Nicole Urban / Jiri Bartek / André Lieber

PLoS ONE, Vol 6, Iss

Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity.

2011 Volume 2

Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2011-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Correction

PLoS ONE, Vol 6, Iss

Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity

2011 Volume 2

Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2011-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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