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  1. Article: Adenoid cystic carcinoma of the head and neck: predictors of morbidity and mortality.

    Fordice, J / Kershaw, C / El-Naggar, A / Goepfert, H

    Archives of otolaryngology--head & neck surgery

    1999  Volume 125, Issue 2, Page(s) 149–152

    Abstract: Objectives: To review 160 patients treated at a single institution for adenoid cystic carcinoma during the 20 years between 1977 and 1996, applying a consistent treatment of surgery and postoperative radiation therapy to 140 patients. To analyze factors ...

    Abstract Objectives: To review 160 patients treated at a single institution for adenoid cystic carcinoma during the 20 years between 1977 and 1996, applying a consistent treatment of surgery and postoperative radiation therapy to 140 patients. To analyze factors governing treatment failure, treatment-related morbidity, and mortality.
    Design: Retrospective review.
    Setting: Tertiary referral center.
    Patients: Seventy-seven males and 83 females aged 13 to 89 years (average age, 49.5 years).
    Results and conclusions: Combined treatment yielded an 85% locoregional freedom from relapse and disease-specific survival at 5, 10, and 15 years was 89%, 67.4%, and 39.6%, respectively. Thirty-five patients (21.9%) had distant metastases as the only site of failure. Patients treated for paranasal sinus tumor experienced the most treatment-related morbidity vs other sites. Perineural invasion of major nerves, positive margins at surgery, and solid histological features were associated with increased treatment failures. Four or more symptoms present at diagnosis, positive lymph nodes, solid histology, and perineural invasion of major nerves were associated with increased mortality from disease.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Carcinoma, Adenoid Cystic/mortality ; Carcinoma, Adenoid Cystic/pathology ; Carcinoma, Adenoid Cystic/radiotherapy ; Carcinoma, Adenoid Cystic/surgery ; Combined Modality Therapy ; Disease-Free Survival ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Otorhinolaryngologic Neoplasms/mortality ; Otorhinolaryngologic Neoplasms/pathology ; Otorhinolaryngologic Neoplasms/radiotherapy ; Otorhinolaryngologic Neoplasms/surgery ; Radiotherapy, Adjuvant ; Survival Rate ; Treatment Failure
    Language English
    Publishing date 1999-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632721-7
    ISSN 1538-361X ; 0886-4470 ; 2168-6181
    ISSN (online) 1538-361X
    ISSN 0886-4470 ; 2168-6181
    DOI 10.1001/archotol.125.2.149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Correlation of the nerve excitability test and electroneurography in acute facial paralysis.

    Coker, N J / Fordice, J O / Moore, S

    The American journal of otology

    1992  Volume 13, Issue 2, Page(s) 127–133

    Abstract: In a retrospective study of 77 patients with acute facial palsy, the results of the nerve excitability test (NET) and electroneurography (ENoG) were analyzed in order to establish a mathematic correlation and to relate the prognostic NET values to ... ...

    Abstract In a retrospective study of 77 patients with acute facial palsy, the results of the nerve excitability test (NET) and electroneurography (ENoG) were analyzed in order to establish a mathematic correlation and to relate the prognostic NET values to quantitative ENoG results. The two tests are related by exponential functions. Coefficients of correlation were higher for the results between NET and the optimized lead placement (OLP) ENoG compared to NET and standardized lead placement (SLP) ENoG. The highest correlation coefficients were demonstrated when NET was performed over the marginal and zygomatic branches of the facial nerve and OLP ENoG recorded in the nasolabial region. Good prognostic NET threshold differences in patients with a small percentage of intact motor axons, calculated by ENoG, may represent segmental demyelination or the deblocking phase of neuropraxia. The tests are complimentary in establishing the integrity of the facial nerve in acute paralysis.
    MeSH term(s) Acute Disease ; Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Electric Stimulation ; Electrodes ; Electrodiagnosis/methods ; Electrophysiology ; Facial Paralysis/diagnosis ; Facial Paralysis/physiopathology ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies
    Language English
    Publishing date 1992-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 800856-5
    ISSN 0192-9763
    ISSN 0192-9763
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  3. Article: Amelanotic melanoma presenting as inflammatory plaques.

    Tschen, J A / Fordice, D B / Reddick, M / Stehlin, J

    Journal of the American Academy of Dermatology

    1992  Volume 27, Issue 3, Page(s) 464–465

    MeSH term(s) Aged ; Erythema/pathology ; Female ; Humans ; Inflammation ; Male ; Melanoma/complications ; Melanoma/pathology ; Middle Aged ; Skin/pathology ; Skin Neoplasms/complications ; Skin Neoplasms/pathology
    Language English
    Publishing date 1992-09
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/s0190-9622(08)80887-0
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  4. Article: Letter: Meals and antibiotic administration times.

    Johnson, T A / Fordice, J J

    American journal of hospital pharmacy

    1976  Volume 33, Issue 2, Page(s) 113

    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Drug Administration Schedule ; Eating ; Humans
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 1976-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80241-4
    ISSN 0002-9289
    ISSN 0002-9289
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  5. Article: Effects of adaptation of vestibulo-ocular reflex function on manual target localization.

    Bloomberg, J J / Merkle, L A / Barry, S R / Huebner, W P / Cohen, H S / Mueller, S A / Fordice, J

    Journal of vestibular research : equilibrium & orientation

    2000  Volume 10, Issue 2, Page(s) 75–86

    Abstract: The goal of the present study was to determine if adaptive modulation of vestibulo-ocular reflex (VOR) function is associated with commensurate alterations in manual target localization. To measure the effects of adapted VOR on manual responses we ... ...

    Abstract The goal of the present study was to determine if adaptive modulation of vestibulo-ocular reflex (VOR) function is associated with commensurate alterations in manual target localization. To measure the effects of adapted VOR on manual responses we developed the Vestibular-Contingent Pointing Test (VCP). In the VCP test, subjects pointed to a remembered target following passive whole body rotation in the dark. In the first experiment, subjects performed VCP before and after wearing 0.5X minifying lenses that adaptively attenuate horizontal VOR gain. Results showed that adaptive reduction in horizontal VOR gain was accompanied by a commensurate change in VCP performance. In the second experiment, bilaterally labyrinthine deficient (LD) subjects were tested to confirm that vestibular cues were central to the spatial coding of both eye and hand movements during VCP. LD subjects performed significantly worse than normal subjects. These results demonstrate that adaptive change in VOR can lead to alterations in manual target localization.
    MeSH term(s) Adaptation, Physiological ; Adult ; Darkness ; Eye Movements ; Female ; Hand/physiology ; Head Movements/physiology ; Humans ; Labyrinth Diseases/physiopathology ; Male ; Movement/physiology ; Psychomotor Performance ; Reference Values ; Reflex, Abnormal ; Reflex, Vestibulo-Ocular ; Rotation ; Spatial Behavior/physiology
    Language English
    Publishing date 2000
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1051840-x
    ISSN 1878-6464 ; 0957-4271
    ISSN (online) 1878-6464
    ISSN 0957-4271
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    Zs.A 3072: Show issues Location:
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  6. Article: Effect of influenza vaccination on plasma phenytoin concentrations.

    Sawchuk, R J / Rector, T S / Fordice, J J / Leppik, I E

    Therapeutic drug monitoring

    1979  Volume 1, Issue 2, Page(s) 285–288

    Abstract: A mean decrease in plasma phenytoin concentrations of 11-14% (p less than 0.005) was observed in seven patients within 4 days after influenza vaccination. Possible mechanisms are discussed. ...

    Abstract A mean decrease in plasma phenytoin concentrations of 11-14% (p less than 0.005) was observed in seven patients within 4 days after influenza vaccination. Possible mechanisms are discussed.
    MeSH term(s) Epilepsy/drug therapy ; Humans ; Influenza Vaccines ; Metabolic Clearance Rate/drug effects ; Phenytoin/blood ; Vaccination
    Chemical Substances Influenza Vaccines ; Phenytoin (6158TKW0C5)
    Language English
    Publishing date 1979
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 424443-6
    ISSN 1536-3694 ; 0163-4356
    ISSN (online) 1536-3694
    ISSN 0163-4356
    DOI 10.1097/00007691-197901020-00010
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  7. Article: Distribution of goldthioglucose in mice with and without experimental allergic encephalomyelitis.

    Boehme, D H / Fordice, M W / Bykowski, J S

    Virchows Archiv. B, Cell pathology

    1974  Volume 15, Issue 4, Page(s) 323–344

    MeSH term(s) Animals ; Aurothioglucose/metabolism ; Biological Transport ; Body Weight/drug effects ; Brain Chemistry ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/metabolism ; Female ; Freund's Adjuvant/pharmacology ; Gold/analysis ; Gold/blood ; Gold/metabolism ; Gold/toxicity ; Histocytochemistry ; Immunization ; Kidney/analysis ; Kupffer Cells/analysis ; Liver/analysis ; Lysosomes/analysis ; Mice ; Organ Size ; Pertussis Vaccine/pharmacology ; Serum Albumin ; Spectrophotometry, Atomic ; Spleen/analysis ; Thymus Gland/analysis
    Chemical Substances Pertussis Vaccine ; Serum Albumin ; Aurothioglucose (2P2V9Q0E78) ; Gold (7440-57-5) ; Freund's Adjuvant (9007-81-2)
    Language English
    Publishing date 1974
    Publishing country Germany
    Document type Comparative Study ; Journal Article
    ZDB-ID 515-0
    ISSN 0042-6431 ; 0340-6075
    ISSN 0042-6431 ; 0340-6075
    DOI 10.1007/bf02889348
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  8. Article: Massive splenomegaly in sarcoidosis.

    Fordice, J / Katras, T / Jackson, R E / Cagle, P T / Jackson, D / Zaleski, H / Asimacopoulos, P J

    Southern medical journal

    1992  Volume 85, Issue 7, Page(s) 775–778

    Abstract: We have presented a case of massive splenomegaly. Our patient was initially thought to have lymphoma, but at operation she was found to have sarcoidosis with splenic involvement. At 2250 g, the spleen was one of the largest recorded in the literature on ... ...

    Abstract We have presented a case of massive splenomegaly. Our patient was initially thought to have lymphoma, but at operation she was found to have sarcoidosis with splenic involvement. At 2250 g, the spleen was one of the largest recorded in the literature on sarcoidosis. Although the spleen is frequently involved in sarcoidosis, a review of 6074 cases showed that the incidence of actual splenomegaly is only 10%. In 628 of these cases the authors described various degrees of splenomegaly, but the incidence of massive splenomegaly was only 3%. We conclude that sarcoidosis must be considered in the differential diagnosis of splenomegaly.
    MeSH term(s) Adult ; Diagnosis, Differential ; Female ; Humans ; Lymphoma/diagnosis ; Sarcoidosis/complications ; Sarcoidosis/diagnosis ; Sarcoidosis/pathology ; Splenomegaly/etiology ; Splenomegaly/pathology
    Language English
    Publishing date 1992-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 185329-6
    ISSN 1541-8243 ; 0038-4348
    ISSN (online) 1541-8243
    ISSN 0038-4348
    DOI 10.1097/00007611-199207000-00028
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  9. Article: Synthesis and analgesic-antiinflammatory activity of some 4- and 5-substituted heteroarylsalicylic acids.

    Jones, H / Fordice, M W / Greenwald, R B / Hannah, J / Jacobs, A / Ruyle, W V / Walford, G L / Shen, T Y

    Journal of medicinal chemistry

    1978  Volume 21, Issue 11, Page(s) 1100–1104

    Abstract: We have made a series of 4- and 5-aryl- and 4- and 5-heteroarylsalicylic acid derivatives with the objective of reducing gastric irritation and increasing potency. Here we describe a series of 4- and 5-heterocyclic salicylic acids and their ... ...

    Abstract We have made a series of 4- and 5-aryl- and 4- and 5-heteroarylsalicylic acid derivatives with the objective of reducing gastric irritation and increasing potency. Here we describe a series of 4- and 5-heterocyclic salicylic acids and their antiinflammatory-analgesic potencies measured in comparison to aspirin. An improvement of the therapeutic index over aspirin of 100 was achieved; however, the heterocyclic salicylic acids lacked antipyretic activity. Some physicochemical parameters which may bear on the antiinflammatory activity of these compounds are discussed.
    MeSH term(s) Animals ; Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Chemical Phenomena ; Chemistry, Physical ; Dogs ; Edema/physiopathology ; Gastrointestinal Hemorrhage/chemically induced ; Rats ; Salicylates/chemical synthesis ; Salicylates/pharmacology
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Salicylates
    Language English
    Publishing date 1978-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218133-2
    ISSN 1520-4804 ; 0022-2623
    ISSN (online) 1520-4804
    ISSN 0022-2623
    DOI 10.1021/jm00209a002
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