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  1. Article ; Online: The administration of lopinavir/ritonavir via an enteral feeding tube.

    Sirvent Segovia, Alejandro Esteban / Alfaro Martínez, José Joaquín

    Endocrinologia, diabetes y nutricion

    2021  Volume 68, Issue 8, Page(s) 596–597

    MeSH term(s) Enteral Nutrition ; HIV Infections/drug therapy ; Humans ; Lopinavir ; Ritonavir
    Chemical Substances Lopinavir (2494G1JF75) ; Ritonavir (O3J8G9O825)
    Language English
    Publishing date 2021-11-22
    Publishing country Spain
    Document type Letter
    ISSN 2530-0180
    ISSN (online) 2530-0180
    DOI 10.1016/j.endien.2020.06.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The administration of lopinavir/ritonavir via an enteral feeding tube.

    Sirvent Segovia, Alejandro Esteban / Alfaro Martínez, José Joaquín

    Endocrinologia, diabetes y nutricion

    2020  

    Title translation Administración de lopinavir/ritonavir a través de sonda de nutrición enteral.
    Keywords covid19
    Language Spanish
    Publishing date 2020-11-06
    Publishing country Spain
    Document type Letter
    ISSN 2530-0180
    ISSN (online) 2530-0180
    DOI 10.1016/j.endinu.2020.06.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Consenso del grupo de trabajo de los trastornos de la conducta alimentaria de SENPE (GTTCA-SENPE). Evaluación y tratamiento médico-nutricional en la anorexia nerviosa. Actualización 2023.

    Campos Del Portillo, Rocío / Palma Milla, Samara / Matía Martín, Pilar / Loria-Kohen, Viviana / Martínez Olmos, Miguel Ángel / Mories Álvarez, María Teresa / Castro Alija, María José / Martín Palmero, María Ángela / Carrillo Lozano, Elena / Valero-Pérez, Marlhyn / Campos Del Portillo, Isabel / Sirvent Segovia, Alejandro Esteban / Plaza Blázquez, Pilar / de la Cruz López, Diana Monserrat / Pita Gutiérrez, Francisco

    Nutricion hospitalaria

    2024  Volume 41, Issue Spec No1, Page(s) 1–60

    Abstract: Introduction: Anorexia nervosa (AN) is a multifactorial disorder. A possible role of the social network and the gut microbiota in pathogenesis has been added. Exogenous shocks such as the COVID19 pandemic have had a negative impact on patients with AN. ... ...

    Title translation A consensus report by the Working Group on Eating Disorders of Sociedad Española de Nutrición Clínica y Metabolismo (GTTCA-SENPE). Evaluation, medical and nutritional management of anorexia nervosa. Update 2023.
    Abstract Introduction: Anorexia nervosa (AN) is a multifactorial disorder. A possible role of the social network and the gut microbiota in pathogenesis has been added. Exogenous shocks such as the COVID19 pandemic have had a negative impact on patients with AN. The potential medical and nutritional impact of malnutrition and/or compensatory behaviors gives rise to a complex disease with a wide range of severity, the management of which requires a multidisciplinary team with a high level of subject matter expertise. Coordination between levels of care is necessary as well as understanding how to transition the patient from pediatric to adult care is essential. A proper clinical evaluation can detect possible complications, as well as establish the organic risk of the patient. This allows caregivers to tailor the medical-nutritional treatment for each patient. Reestablishing adequate nutritional behaviors is a fundamental pillar of treatment in AN. The design of a personalized nutritional treatment and education program is necessary for this purpose. Depending on the clinical severity, artificial nutrition may be necessary. Although the decision regarding the level of care necessary at diagnosis or during follow-up depends on a number of factors (awareness of the disease, medical stability, complications, suicidal risk, outpatient treatment failure, psychosocial context, etc.), outpatient treatment is the most frequent and most preferred choice. However, more intensive care (total or partial hospitalization) may be necessary in certain cases. In severely malnourished patients, the appearance of refeeding syndrome should be prevented during renourishment. The presence of AN in certain situations (pregnancy, vegetarianism, type 1 diabetes mellitus) requires specific care. Physical activity in these patients must also be addressed correctly.
    MeSH term(s) Adult ; Humans ; Child ; Anorexia Nervosa/complications ; Anorexia Nervosa/therapy ; Anorexia Nervosa/psychology ; Consensus ; Transition to Adult Care ; Feeding and Eating Disorders ; Malnutrition/therapy
    Language Spanish
    Publishing date 2024-01-24
    Publishing country Spain
    Document type English Abstract ; Journal Article
    ZDB-ID 1481223-x
    ISSN 1699-5198 ; 0212-1611
    ISSN (online) 1699-5198
    ISSN 0212-1611
    DOI 10.20960/nh.05175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Consenso del grupo de trabajo de los trastornos de la conducta alimentaria de SENPE (GTTCA-SENPE). Evaluación y tratamiento médico-nutricional en la anorexia nerviosa. Actualización 2023.

    Campos Del Portillo, Rocío / Palma Milla, Samara / Matía Martín, Pilar / Loria-Kohen, Viviana / Martínez Olmos, Miguel Ángel / Mories Álvarez, María Teresa / Castro Alija, María José / Martín Palmero, María Ángela / Carrillo Lozano, Elena / Valero-Pérez, Marlhyn / Campos Del Portillo, María Isabel / Sirvent Segovia, Alejandro Esteban / Plaza Blázquez, Pilar / de la Cruz López, Diana Monserrat / Pita, Francisco

    Nutricion hospitalaria

    2024  

    Abstract: Anorexia nervosa (AN) is a multifactorial disorder. A possible role of the social network and the gut microbiota in pathogenesis has been added. Exogenous shocks such as the COVID19 pandemic have had a negative impact on patients with AN. The potential ... ...

    Title translation Consenso del grupo de trabajo de los trastornos de la conducta alimentaria de SENPE (GTTCA-SENPE). Evaluación y tratamiento médico-nutricional en la anorexia nerviosa. Actualización 2023.
    Abstract Anorexia nervosa (AN) is a multifactorial disorder. A possible role of the social network and the gut microbiota in pathogenesis has been added. Exogenous shocks such as the COVID19 pandemic have had a negative impact on patients with AN. The potential medical and nutritional impact of malnutrition and/or compensatory behaviors gives rise to a complex disease with a wide range of severity, the management of which requires a multidisciplinary team with a high level of subject matter expertise. Coordination between levels of care is necessary as well as understanding how to transition the patient from pediatric to adult care is essential. A proper clinical evaluation can detect possible complications, as well as establish the organic risk of the patient. This allows caregivers to tailor the medical-nutritional treatment for each patient. Reestablishing adequate nutritional behaviors is a fundamental pillar of treatment in AN. The design of a personalized nutritional treatment and education program is necessary for this purpose. Depending on the clinical severity, artificial nutrition may be necessary. Although the decision regarding the level of care necessary at diagnosis or during follow-up depends on a number of factors (awareness of the disease, medical stability, complications, suicidal risk, outpatient treatment failure, psychosocial context, etc.), outpatient treatment is the most frequent and most preferred choice. However, more intensive care (total or partial hospitalization) may be necessary in certain cases. In severely malnourished patients, the appearance of refeeding syndrome should be prevented during renourishment. The presence of AN in certain situations (pregnancy, vegetarianism, type 1 diabetes mellitus) requires specific care. Physical activity in these patients must also be addressed correctly.
    Language Spanish
    Publishing date 2024-02-06
    Publishing country Spain
    Document type English Abstract ; Journal Article
    ZDB-ID 1481223-x
    ISSN 1699-5198 ; 0212-1611
    ISSN (online) 1699-5198
    ISSN 0212-1611
    DOI 10.20960/nh.05175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Analysis of the evolution of the publication of case reports in endocrinology journals.

    López García, María Carmen / Moya Moya, Antonio José / Sirvent Segovia, Alejandro Esteban / Ruiz de Assin Valverde, Andrés / García Blasco, Lourdes / Quilez Toboso, Rosa Pilar / Alfaro Martínez, José Joaquín

    Endocrinologia, diabetes y nutricion

    2022  Volume 69, Issue 3, Page(s) 189–193

    Abstract: Introduction: A case report is a scientific article describing one or more patients with unusual clinical presentations. In recent years, the number of case reports in publications has decreased. In this study, we analyze the publication of case reports ...

    Abstract Introduction: A case report is a scientific article describing one or more patients with unusual clinical presentations. In recent years, the number of case reports in publications has decreased. In this study, we analyze the publication of case reports in journals of Endocrinology during the years 2010, 2015 and 2019.
    Materials and methods: The Pubmed web was browsed for clinical journals of Endocrinology, those published in English and/or Spanish being selected, and the relevant variables analyzed.
    Results: Of 84 analyzed journals, 51 accepted cases for publication, 29 did not, and 4 did so only in exceptional cases. In 2010, 11,754 articles were published, of which 709 were clinical cases (6.9% of the total); in 2015, a total of 14,594 articles of which 655 were clinical cases (5.8% of the total); and in 2019 a total of 14,110 articles, of which 472 were clinical cases (4.6% of the total). In journals demanding payment for the publishing of clinical cases, case reports represented 9% of all articles, and in free journals, 3% (P < 0.05).
    Conclusion: There has been a decline in publication of case reports in journals of Endocrinology in recent years, both in absolute and relative terms. Even though the cases described by these reports are, by definition, exceptional, the decline of their publication implies a significant loss of scientific information and clinical knowledge regarding certain pathologies.
    MeSH term(s) Endocrinology ; Humans ; Periodicals as Topic ; Publishing
    Language English
    Publishing date 2022-02-28
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ISSN 2530-0180
    ISSN (online) 2530-0180
    DOI 10.1016/j.endien.2022.02.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Analysis of the evolution of the publication of case reports in endocrinology journals.

    López García, María Carmen / Moya Moya, Antonio José / Sirvent Segovia, Alejandro Esteban / Ruiz de Assin Valverde, Andrés / García Blasco, Lourdes / Quilez Toboso, Rosa Pilar / Alfaro Martínez, José Joaquín

    Endocrinologia, diabetes y nutricion

    2021  

    Abstract: Introduction: A case report is a scientific article describing one or more patients with unusual clinical presentations. In recent years, the number of case reports in publications has decreased. In this study, we analyze the publication of case reports ...

    Title translation Análisis de la evolución en la publicación de casos clínicos en revistas de endocrinología.
    Abstract Introduction: A case report is a scientific article describing one or more patients with unusual clinical presentations. In recent years, the number of case reports in publications has decreased. In this study, we analyze the publication of case reports in journals of Endocrinology during the years 2010, 2015 and 2019.
    Materials and methods: The Pubmed web was browsed for clinical journals of Endocrinology, those published in English and/or Spanish being selected, and the relevant variables analyzed.
    Results: Of 84 analyzed journals, 51 accepted cases for publication, 29 did not, and 4 did so only in exceptional cases. In 2010, 11,754 articles were published, of which 709 were clinical cases (6.9% of the total); in 2015, a total of 14,594 articles of which 655 were clinical cases (5.8% of the total); and in 2019 a total of 14,110 articles, of which 472 were clinical cases (4.6% of the total). In journals demanding payment for the publishing of clinical cases, case reports represented 9% of all articles, and in free journals, 3% (P<.05).
    Conclusion: There has been a decline in publication of case reports in journals of Endocrinology in recent years, both in absolute and relative terms. Even though the cases described by these reports are, by definition, exceptional, the decline of their publication implies a significant loss of scientific information and clinical knowledge regarding certain pathologies.
    Language Spanish
    Publishing date 2021-05-28
    Publishing country Spain
    Document type Journal Article
    ISSN 2530-0180
    ISSN (online) 2530-0180
    DOI 10.1016/j.endinu.2021.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Vasculopatías cerebrales por consumo de drogas de abuso en pacientes adultos

    Antonio José Moya Moya / Fátima María Madrona Marcos / Alejandro Esteban Sirvent Segovia / Ricardo Rodenas Lozano / Maria José Villar Inarejos

    Jounal of Negative and No Positive Results, Pp 197-

    A propósito de un caso

    2020  Volume 202

    Abstract: Introducción. La enfermedad de moyamoya es una enfermedad cerebrovascular que se caracteriza por la estenosis progresiva de las arterias del polígono de Willis, desarrollando una red vascular compensatoria anómala, denominada vasos moyamoya. Dichas áreas ...

    Abstract Introducción. La enfermedad de moyamoya es una enfermedad cerebrovascular que se caracteriza por la estenosis progresiva de las arterias del polígono de Willis, desarrollando una red vascular compensatoria anómala, denominada vasos moyamoya. Dichas áreas son más susceptibles de sufrir isquemia o hemorragia. Caso clínico. Varón de 47 años con clínica de debilidad en miembro superior izquierdo y torpeza en la marcha en miembro inferior izquierdo, de 5 días de evolución, en relación con consumo de cocaína. En arteriografía, red colateral compatible con patrón de moyamoya. Discusión. El consumo crónico de cocaína produce aumento brusco de la presión arterial, vasoconstricción cerebral, vasculitis y trombosis aguda, con el consecuente desarrollo de vasos moyamoya como mecanismo fisiológico compensatorio.
    Keywords caso clínico ; cocaína ; drogas de abuso ; síndrome de moyamoya ; ictus ; vasculopatía adquirida ; Medicine ; R ; Science ; Q
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher Asociación Para el Progreso de la Biomedicina
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Generation and validation of in-hospital mortality prediction score in COVID-19 patients: Alba-score.

    Alfaro-Martínez, José-Joaquín / Calbo Mayo, Juan / Molina Cifuentes, María / Abizanda Soler, Pedro / Guillén Martínez, Sergio / Rodríguez Marín, Yulema / Sirvent Segovia, Alejandro Esteban / Nuñez Ares, Ana / Alcaraz Barcelona, Marina / Paterna Mellinas, Gema / Cuesta Vizcaíno, Encarna / Martínez Alfaro, Elisa / Solís García Del Pozo, Julián

    Current medical research and opinion

    2021  Volume 37, Issue 5, Page(s) 719–726

    Abstract: Background: COVID-19 has a wide range of symptoms reported, which may vary from very mild cases (even asymptomatic) to deadly infections. Identifying high mortality risk individuals infected with the SARS-CoV-2 virus through a prediction instrument that ...

    Abstract Background: COVID-19 has a wide range of symptoms reported, which may vary from very mild cases (even asymptomatic) to deadly infections. Identifying high mortality risk individuals infected with the SARS-CoV-2 virus through a prediction instrument that uses simple clinical and analytical parameters at admission can help clinicians to focus on treatment efforts in this group of patients.
    Methods: Data was obtained retrospectively from the electronic medical record of all COVID-19 patients hospitalized in the Albacete University Hospital Complex until July 2020. Patients were split into two: a generating and a validating cohort. Clinical, demographical and laboratory variables were included. A multivariate logistic regression model was used to select variables associated with in-hospital mortality in the generating cohort. A numerical and subsequently a categorical score according to mortality were constructed (A: mortality from 0% to 5%; B: from 5% to 15%; C: from 15% to 30%; D: from 30% to 50%; E: greater than 50%). These scores were validated with the validation cohort.
    Results: Variables independently related to mortality during hospitalization were age, diabetes mellitus, confusion, SaFiO2, heart rate and lactate dehydrogenase (LDH) at admission. The numerical score defined ranges from 0 to 13 points. Scores included are: age ≥71 years (3 points), diabetes mellitus (1 point), confusion (2 points), onco-hematologic disease (1 point), SaFiO2 ≤ 419 (3 points), heart rate ≥ 100 bpm (1 point) and LDH ≥ 390 IU/L (2 points). The area under the curve (AUC) for the numerical and categorical scores from the generating cohort were 0.8625 and 0.848, respectively. In the validating cohort, AUCs were 0.8505 for the numerical score and 0.8313 for the categorical score.
    Conclusions: Data analysis found a correlation between clinical admission parameters and in-hospital mortality for COVID-19 patients. This correlation is used to develop a model to assist physicians in the emergency department in the COVID-19 treatment decision-making process.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Area Under Curve ; COVID-19/diagnosis ; COVID-19/mortality ; COVID-19/therapy ; Cohort Studies ; Electronic Health Records ; Emergency Service, Hospital ; Female ; Hospital Mortality ; Hospitalization ; Humans ; Logistic Models ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Risk Assessment ; SARS-CoV-2 ; Spain
    Language English
    Publishing date 2021-03-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 80296-7
    ISSN 1473-4877 ; 0300-7995
    ISSN (online) 1473-4877
    ISSN 0300-7995
    DOI 10.1080/03007995.2021.1891036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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