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Article ; Online: Adrenal vein sampling: how to make it quick, easy, and successful.

Daunt, Nicholas

Radiographics : a review publication of the Radiological Society of North America, Inc

2005 Volume 25 Suppl 1, Page(s) S143–58

Abstract: Adrenal vein sampling has a reputation as a difficult procedure. However, it is being performed more frequently at some institutions due to the realization that primary aldosteronism is more common than previously believed. At the author's institution, ... ...

Abstract	Adrenal vein sampling has a reputation as a difficult procedure. However, it is being performed more frequently at some institutions due to the realization that primary aldosteronism is more common than previously believed. At the author's institution, adrenal vein sampling with computed tomographic (CT) and laboratory correlation has been performed more than 800 times in the past 10 years. Adrenal vein sampling is used to determine whether autonomous hormone production is unilateral or bilateral; unilateral secretion can be treated with surgery. The venous drainage of each adrenal gland is predominantly via a central vein. Recognition of the right adrenal vein is the crux of adrenal vein sampling. CT is useful in planning adrenal vein sampling by demonstrating the anatomy and positions of the adrenal veins. A small amount of contrast material is injected gently and slowly into the adrenal vein; it is not necessary to perform formal venography to outline the entire gland. To confirm that the vein is draining the majority of adrenal cortical blood, the adrenal vein sample should have a significantly higher level of cortisol than a peripheral sample. Adrenal glands that are producing aldosterone demonstrate an aldosterone-cortisol ratio that is higher than the peripheral value.
MeSH term(s)	Adrenal Glands/blood supply ; Adrenal Glands/diagnostic imaging ; Aldosterone/blood ; Humans ; Hyperaldosteronism/blood ; Phlebotomy/methods ; Radiography
Chemical Substances	Aldosterone (4964P6T9RB)
Language	English
Publishing date	2005-10
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	603172-9
ISSN	1527-1323 ; 0271-5333
ISSN (online)	1527-1323
ISSN	0271-5333
DOI	10.1148/rg.25si055514
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Article: Magnetic resonance imaging of the wrist: anatomy and pathology of interosseous ligaments and the triangular fibrocartilage complex.

Daunt, Nicholas

Current problems in diagnostic radiology

2002 Volume 31, Issue 4, Page(s) 158–176

Abstract: The complex anatomy of the radiocarpal joint and proximal carpus renders high-quality magnetic resonance imaging difficult and interpretation more problematic than in other areas of the skeleton. Added to this, the common occurrence of abnormal ... ...

Abstract	The complex anatomy of the radiocarpal joint and proximal carpus renders high-quality magnetic resonance imaging difficult and interpretation more problematic than in other areas of the skeleton. Added to this, the common occurrence of abnormal communications through the triangular fibrocartilage complex, scapholunate, and lunotriquetral ligaments often results in difficulty in assessing the importance of findings. This article reviews the anatomy, gives suggestions for protocols for scanning the wrist, and reviews the pathologic conditions that may be seen in these structures. In particular, it emphasizes the 3-dimensional nature of these structures and how best to evaluate them in axial, coronal, and sagittal planes.
MeSH term(s)	Cartilage/diagnostic imaging ; Cartilage/pathology ; Humans ; Ligaments, Articular/diagnostic imaging ; Ligaments, Articular/pathology ; Magnetic Resonance Imaging ; Radiography ; Wrist Joint/diagnostic imaging ; Wrist Joint/pathology
Language	English
Publishing date	2002-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	198954-6
ISSN	0363-0188
ISSN	0363-0188
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Article: Esophageal Dilatation Post - Gastric Banding And Catheter Ablation For Atrial Fibrillation: A Case Report.

Townsend, Simon / James, Andrew / Daunt, Nicholas / Phillips, Karen P

Journal of atrial fibrillation

2009 Volume 2, Issue 1, Page(s) 188

Abstract: Esophageal injury is a potential serious complication of catheter ablation for atrial fibrillation. We report a case of significant esophageal dilatation following previous laparascopic gastric banding in a patient with permanent atrial fibrillation ... ...

Abstract	Esophageal injury is a potential serious complication of catheter ablation for atrial fibrillation. We report a case of significant esophageal dilatation following previous laparascopic gastric banding in a patient with permanent atrial fibrillation undergoing a pulmonary vein isolation procedure.
Language	English
Publishing date	2009-06-01
Publishing country	United States
Document type	Case Reports
ZDB-ID	2451936-4
ISSN	1941-6911
ISSN	1941-6911
DOI	10.4022/jafib.188
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Article ; Online: Hyperreninemic hypertension following presumed abdominal trauma.

Pimenta, Eduardo / Gordon, Richard D / Daunt, Nicholas / Slater, Gregory / Stowasser, Michael

Nature reviews. Nephrology

2011 Volume 7, Issue 12, Page(s) 730–734

Abstract: Background: An 18-year-old previously normotensive man was referred to a hypertension unit with blood pressure readings of 140-150/100-110 mmHg. Renal ultrasound had shown a right renal subcapsular fluid collection and an abdominal computed tomography ... ...

Abstract	Background: An 18-year-old previously normotensive man was referred to a hypertension unit with blood pressure readings of 140-150/100-110 mmHg. Renal ultrasound had shown a right renal subcapsular fluid collection and an abdominal computed tomography scan had revealed a large cystic lesion surrounding the right kidney with a thick wall and irregular peripheral calcification consistent with a long-standing traumatic perinephric hematoma. Investigations: Physical examination, renal artery duplex ultrasonography, magnetic resonance imaging of the abdomen, isotopic renography with technetium-99m diethylenetriamine pentaacetic acid, and a renal venous renin ratio study. Diagnosis: Hyperreninemic hypertension as a result of presumed abdominal trauma. Management: Removal of the affected kidney.
MeSH term(s)	Abdominal Injuries/blood ; Abdominal Injuries/complications ; Abdominal Injuries/diagnosis ; Adolescent ; Biomarkers/blood ; Blood Pressure ; Diagnosis, Differential ; Humans ; Hypertension/blood ; Hypertension/diagnosis ; Hypertension/etiology ; Magnetic Resonance Imaging ; Male ; Radioisotope Renography ; Renal Artery/injuries ; Renin/blood ; Tomography, X-Ray Computed ; Trauma Severity Indices
Chemical Substances	Biomarkers ; Renin (EC 3.4.23.15)
Language	English
Publishing date	2011-09-27
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2490366-8
ISSN	1759-507X ; 1759-5061
ISSN (online)	1759-507X
ISSN	1759-5061
DOI	10.1038/nrneph.2011.127
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Zs.A 6334: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Repeating adrenal vein sampling when neither aldosterone/cortisol ratio exceeds peripheral yields a high incidence of aldosterone-producing adenoma.

Wolley, Martin / Gordon, Richard D / Pimenta, Eduardo / Daunt, Nicholas / Slater, Gregory J / Ahmed, Ashraf H / Stowasser, Michael

Journal of hypertension

2013 Volume 31, Issue 10, Page(s) 2005–2009

Abstract: Objectives: In primary aldosteronism, adrenal vein sampling (AVS) suggests unilateral aldosterone-producing adenoma (APA) when the aldosterone/cortisol (A/F) ratio is less than or equal to peripheral on one side and at least two times peripheral on the ... ...

Abstract	Objectives: In primary aldosteronism, adrenal vein sampling (AVS) suggests unilateral aldosterone-producing adenoma (APA) when the aldosterone/cortisol (A/F) ratio is less than or equal to peripheral on one side and at least two times peripheral on the other. When A/F ratios are lower bilaterally than peripheral despite adequate samples (adrenal venous cortisol ≥3 times peripheral), we recommend repeat AVS. This study aimed to determine the frequency of this occurrence and outcomes in such cases. Methods: We performed a retrospective observational study of all cases of primary aldosteronism undergoing initial AVS over a 34-year period. Results: Initial AVS in 1397 patients returned satisfactory and discriminatory results in 1066 (76.3%) but 37 patients (2.6%) had adequate samples but bilateral A/F ratios no higher than peripheral. Of the 22 of these 37 who agreed to repeat AVS, 10 demonstrated unilateral aldosterone production, and eight of these had unilateral adrenalectomy disclosing APAs and resulting in cure (3) or improvement (5) in hypertension. Eight had bilateral aldosterone production. Four studies were inconclusive. Patients with initial unsatisfactory AVS because of bilaterally low A/F ratios had significantly (P=0.023) more unilateral disease [10 of 18 satisfactory repeat studies (55.6%) vs. 326 of 1066 satisfactory initial studies (30.6%)] and a significantly higher (67.6 vs. 49.9%, P=0.034) percentage of males. Conclusion: As the incidence of APAs was high in a subgroup with low A/F bilaterally on initial AVS, these patients should be offered repeat AVS. This might reflect both a greater dependence of aldosterone production on adrenocorticotrophic hormone (ACTH) in APAs and the pulsatile nature of ACTH secretion.
MeSH term(s)	Adenoma/blood ; Adenoma/diagnosis ; Adrenal Glands/blood supply ; Adrenocorticotropic Hormone/metabolism ; Adult ; Aldosterone/blood ; Female ; Hematologic Tests/methods ; Humans ; Hydrocortisone/blood ; Hyperaldosteronism/diagnosis ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; Sex Factors ; Veins ; Young Adult
Chemical Substances	Aldosterone (4964P6T9RB) ; Adrenocorticotropic Hormone (9002-60-2) ; Hydrocortisone (WI4X0X7BPJ)
Language	English
Publishing date	2013-10
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	605532-1
ISSN	1473-5598 ; 0263-6352 ; 0952-1178
ISSN (online)	1473-5598
ISSN	0263-6352 ; 0952-1178
DOI	10.1097/HJH.0b013e328362add3
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Zs.A 1885: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Esophageal Dilatation Post - Gastric Banding And Catheter Ablation For Atrial Fibrillation

Simon Townsend / Andrew James / Nicholas Daunt / Karen P. Phillips

Journal of Atrial Fibrillation, Vol 1, Iss 7, Pp 451-

A Case Report

2009 Volume 453

Abstract	Esophageal injury is a potential serious complication of catheter ablation for atrial fibrillation. We report a case of significant esophageal dilatation following previous laparascopic gastric banding in a patient with permanent atrial fibrillation undergoing a pulmonary vein isolation procedure.
Keywords	Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2009-06-01T00:00:00Z
Publisher	CardioFront
Document type	Article ; Online
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Article ; Online: North Atlantic winter cyclones starve seabirds.

Clairbaux, Manon / Mathewson, Paul / Porter, Warren / Fort, Jérôme / Strøm, Hallvard / Moe, Børge / Fauchald, Per / Descamps, Sebastien / Helgason, Hálfdán H / Bråthen, Vegard S / Merkel, Benjamin / Anker-Nilssen, Tycho / Bringsvor, Ingar S / Chastel, Olivier / Christensen-Dalsgaard, Signe / Danielsen, Jóhannis / Daunt, Francis / Dehnhard, Nina / Erikstad, Kjell Einar /

Ezhov, Alexey / Gavrilo, Maria / Krasnov, Yuri / Langset, Magdalene / Lorentsen, Svein-H / Newell, Mark / Olsen, Bergur / Reiertsen, Tone K / Systad, Geir Helge / Thórarinsson, Thorkell L / Baran, Mark / Diamond, Tony / Fayet, Annette L / Fitzsimmons, Michelle G / Frederiksen, Morten / Gilchrist, Hugh G / Guilford, Tim / Huffeldt, Nicholas P / Jessopp, Mark / Johansen, Kasper L / Kouwenberg, Amy-Lee / Linnebjerg, Jannie F / Major, Heather L / Tranquilla, Laura McFarlane / Mallory, Mark / Merkel, Flemming R / Montevecchi, William / Mosbech, Anders / Petersen, Aevar / Grémillet, David

Current biology : CB

2021 Volume 31, Issue 17, Page(s) 3964–3971.e3

Abstract: Each winter, the North Atlantic Ocean is the stage for numerous cyclones, the most severe ones leading to seabird mass-mortality events called "winter wrecks." ...

Abstract	Each winter, the North Atlantic Ocean is the stage for numerous cyclones, the most severe ones leading to seabird mass-mortality events called "winter wrecks."
MeSH term(s)	Animals ; Atlantic Ocean ; Birds ; Charadriiformes ; Cyclonic Storms ; Humans ; Seasons
Language	English
Publishing date	2021-09-14
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1071731-6
ISSN	1879-0445 ; 0960-9822
ISSN (online)	1879-0445
ISSN	0960-9822
DOI	10.1016/j.cub.2021.06.059
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Article ; Online: Meeting Paris agreement objectives will temper seabird winter distribution shifts in the North Atlantic Ocean.

Clairbaux, Manon / Cheung, William W L / Mathewson, Paul / Porter, Warren / Courbin, Nicolas / Fort, Jérôme / Strøm, Hallvard / Moe, Børge / Fauchald, Per / Descamps, Sebastien / Helgason, Hálfdán / Bråthen, Vegard S / Merkel, Benjamin / Anker-Nilssen, Tycho / Bringsvor, Ingar S / Chastel, Olivier / Christensen-Dalsgaard, Signe / Danielsen, Jóhannis / Daunt, Francis /

Dehnhard, Nina / Erikstad, Kjell-Einar / Ezhov, Alexeï / Gavrilo, Maria / Krasnov, Yuri / Langset, Magdalene / Lorentsen, Svein-Håkon / Newell, Mark / Olsen, Bergur / Reiertsen, Tone Kirstin / Systad, Geir / Þórarinsson, Þorkell L / Baran, Mark / Diamond, Tony / Fayet, Annette L / Fitzsimmons, Michelle G / Frederiksen, Morten / Gilchrist, Grant H / Guilford, Tim / Huffeldt, Nicholas P / Jessopp, Mark / Johansen, Kasper L / Kouwenberg, Amy L / Linnebjerg, Jannie F / McFarlane Tranquilla, Laura / Mallory, Mark / Merkel, Flemming R / Montevecchi, William / Mosbech, Anders / Petersen, Aevar / Grémillet, David

Global change biology

2021 Volume 27, Issue 7, Page(s) 1457–1469

Abstract: We explored the implications of reaching the Paris Agreement Objective of limiting global warming to <2°C for the future winter distribution of the North Atlantic seabird community. We predicted and quantified current and future winter habitats of five ... ...

Abstract	We explored the implications of reaching the Paris Agreement Objective of limiting global warming to <2°C for the future winter distribution of the North Atlantic seabird community. We predicted and quantified current and future winter habitats of five North Atlantic Ocean seabird species (Alle alle, Fratercula arctica, Uria aalge, Uria lomvia and Rissa tridactyla) using tracking data for ~1500 individuals through resource selection functions based on mechanistic modeling of seabird energy requirements, and a dynamic bioclimate envelope model of seabird prey. Future winter distributions were predicted to shift with climate change, especially when global warming exceed 2°C under a "no mitigation" scenario, modifying seabird wintering hotspots in the North Atlantic Ocean. Our findings suggest that meeting Paris agreement objectives will limit changes in seabird selected habitat location and size in the North Atlantic Ocean during the 21st century. We thereby provide key information for the design of adaptive marine-protected areas in a changing ocean.
MeSH term(s)	Animals ; Atlantic Ocean ; Climate Change ; Ecosystem ; Humans ; Paris ; Seasons
Language	English
Publishing date	2021-01-20
Publishing country	England
Document type	Journal Article
ZDB-ID	1281439-8
ISSN	1365-2486 ; 1354-1013
ISSN (online)	1365-2486
ISSN	1354-1013
DOI	10.1111/gcb.15497
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Article ; Online: Esophageal Dilatation Post – Gastric Banding And Catheter Ablation For Atrial Fibrillation

Simon Townsend / Andrew James / Nicholas Daunt MBBS / Karen P. Phillips MBBS

Journal of Atrial Fibrillation, Vol 2, Iss 1, Pp 15-

A Case Report

2009 Volume 18

Abstract	Esophageal injury is a potential serious complication of catheter ablation for atrial fibrillation. We report a case of significant esophageal dilatation following previous laparascopic gastric banding in a patient with permanent atrial fibrillation undergoing a pulmonary vein isolation procedure.
Keywords	Internal medicine ; RC31-1245 ; Medicine ; R
Language	English
Publishing date	2009-06-01T00:00:00Z
Publisher	CardioFront
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism.

Mulatero, Paolo / Bertello, Chiara / Sukor, Norlela / Gordon, Richard / Rossato, Denis / Daunt, Nicholas / Leggett, David / Mengozzi, Giulio / Veglio, Franco / Stowasser, Michael

Hypertension (Dallas, Tex. : 1979)

2010 Volume 55, Issue 3, Page(s) 667–673

Abstract: In patients with primary aldosteronism, adrenal vein sampling (AVS) is considered the only reliable technique to distinguish between unilateral and bilateral autonomous production of aldosterone, but agreement is lacking on the best criteria indicating ... ...

Abstract	In patients with primary aldosteronism, adrenal vein sampling (AVS) is considered the only reliable technique to distinguish between unilateral and bilateral autonomous production of aldosterone, but agreement is lacking on the best criteria indicating successful cannulation and lateralization. The objective of this study was to assess the impact of differing criteria for the successful cannulation and lateralization on the reproducibility of subtype diagnosis. Sixty-two patients with confirmed primary aldosteronism underwent AVS on 2 separate occasions, because the first was unsatisfactory. We compared the different diagnoses of primary aldosteronism subtype reached using AVS data assessed by permissive (type 1), intermediate (type 2), and strict (type 3) criteria. Although 91.1% of all of the (both first and second) AVSs were "successful" by type 1 criteria (50.8% by type 2 and 33.9% by type 3), in only 35.3% of patients was the diagnosis concordant between the first and second AVS. Type 1 criteria also led to a higher rate of diagnosis of unilateral primary aldosteronism (67.3% of successful procedures) than type 2 (36.5%) or type 3 (26.2%). There was considerable disparity in the diagnosis reached using the 3 different criteria, with concordance in only 32.2%. Using either type 1 or 2 criteria, the minimal adrenal/peripheral vein cortisol ratio necessary to obtain the same diagnosis in the first and second AVS procedures was >/=2.75. In conclusion, permissive criteria for successful cannulation and lateralization on AVS achieve poor diagnostic reproducibility and should be avoided.
MeSH term(s)	Adenoma/blood ; Adenoma/diagnosis ; Adrenal Gland Neoplasms/blood ; Adrenal Gland Neoplasms/complications ; Adrenal Gland Neoplasms/diagnosis ; Adrenal Glands/blood supply ; Adrenal Hyperplasia, Congenital/blood ; Adrenal Hyperplasia, Congenital/complications ; Adrenal Hyperplasia, Congenital/diagnosis ; Aldosterone/blood ; Catheterization/standards ; Diagnostic Techniques, Cardiovascular/standards ; Diagnostic Techniques, Endocrine/standards ; Female ; Humans ; Hydrocortisone/blood ; Hyperaldosteronism/blood ; Hyperaldosteronism/diagnosis ; Hyperaldosteronism/etiology ; Hypertension/blood ; Hypertension/diagnosis ; Hypertension/etiology ; Male ; Middle Aged ; Reproducibility of Results ; Veins
Chemical Substances	Aldosterone (4964P6T9RB) ; Hydrocortisone (WI4X0X7BPJ)
Language	English
Publishing date	2010-03
Publishing country	United States
Document type	Clinical Trial ; Journal Article ; Validation Studies
ZDB-ID	423736-5
ISSN	1524-4563 ; 0194-911X ; 0362-4323
ISSN (online)	1524-4563
ISSN	0194-911X ; 0362-4323
DOI	10.1161/HYPERTENSIONAHA.109.146613
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